Ocular Surface Membrane-Associated Mucins

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salivary mucin (MG1) as tracheobronchial mucin MUC5B, Glycobiology, 7, 413, 10.1093/glycob/7.3.413 Jumblatt, 2003, MUC7 expression in the human lacrimal gland and conjunctiva, Cornea, 22, 41, 10.1097/00003226-200301000-00010 Argueso, 2003, MUC16 mucin is expressed by the human ocular surface epithelia and carries the H185 carbohydrate epitope, Invest Ophthalmol Vis Sci, 44, 2487, 10.1167/iovs.02-0862 Woodward, 2014, Expression analysis of the transmembrane mucin MUC20 in human corneal and conjunctival epithelia, Invest Ophthalmol Vis Sci, 55, 6132, 10.1167/iovs.14-15269 Gipson, 2004, Character of ocular surface mucins and their alteration in dry eye disease, Ocul Surf, 2, 131, 10.1016/S1542-0124(12)70149-0 Danjo, 1998, Alteration of mucin in human conjunctival epithelia in dry eye, Invest Ophthalmol Vis Sci, 39, 2602 Moniaux, 2001, Structural organization and classification of the human mucin genes, Front Biosci, 6, D1192, 10.2741/Moniaux Gendler, 1995, Epithelial mucin genes, Ann Rev 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airways disease, Cell, 95, 1005, 10.1016/S0092-8674(00)81724-9 Derichs, 2011, Hyperviscous airway periciliary and mucous liquid layers in cystic fibrosis measured by confocal fluorescence photobleaching, FASEB J, 25, 2325, 10.1096/fj.10-179549 Kesimer, 2013, Molecular organization of the mucins and glycocalyx underlying mucus transport over mucosal surfaces of the airways, Mucosal Immunol, 379, 10.1038/mi.2012.81 Lan, 1990, Cloning and sequencing of a human pancreatic tumor mucin cDNA, J Biol Chem, 265, 15294, 10.1016/S0021-9258(18)77255-4 Jonckheere, 2013, Membrane-bound mucin modular domains: From structure to function, Biochimie, 95, 1077, 10.1016/j.biochi.2012.11.005 Macao, 2006, Autoproteolysis coupled to protein folding in the SEA domain of the membrane-bound MUC1 mucin, Nat Struct Mol Biol, 13, 71, 10.1038/nsmb1035 Blalock, 2008, Release of membrane-associated mucins from ocular surface epithelia, Invest Ophthalmol Vis Sci, 49, 1864, 10.1167/iovs.07-1081 Alam, 2014, Targeting the MUC1-C oncoprotein inhibits self-renewal capacity of breast cancer cells, Oncotarget, 5, 2622, 10.18632/oncotarget.1848 Hanisch, 2000, MUC1: the polymorphic appearance of a human mucin, Glycobiology, 10, 439, 10.1093/glycob/10.5.439 Hilkens, 1992, Cell membrane-associated mucins and their adhesion-modulating property, Trends Biochem Sci, 17, 359, 10.1016/0968-0004(92)90315-Z Premaratne, 2011, O-glycosylation of MUC1 mucin in prostate cancer and the effects of its expression on tumor growth in a prostate cancer xenograft model, Tumour Biol, 32, 203, 10.1007/s13277-010-0114-9 Banerjee, 2015, Epithelial MUC1 promotes cell migration, reduces apoptosis and affects levels of mucosal modulators during acetylsalicylic acid (aspirin)-induced gastropathy, Biochem J, 465, 423, 10.1042/BJ20140617 Horm, 2013, MUC1 and metastatic cancer: expression, function and therapeutic targeting, Cell Adhesion Migration, 7, 187, 10.4161/cam.23131 Lillehoj, 2004, Pseudomonas aeruginosa stimulates phosphorylation of the airway epithelial membrane glycoprotein Muc1 and activates MAP kinase, Am J Physiol Lung Cell Mol Physiol, 287, L809, 10.1152/ajplung.00385.2003 Kato, 2010, MUC1 expression by human airway epithelial cells mediates Pseudomonas aeruginosa adhesion, Front Biosci (Elite Ed), 2, 68 Lu, 2006, Cutting edge: enhanced pulmonary clearance of Pseudomonas aeruginosa by Muc1 knockout mice, J Immunol, 176, 3890, 10.4049/jimmunol.176.7.3890 Gipson, 2014, Comparison of the transmembrane mucins MUC1 and MUC16 in epithelial barrier function, PloS One, 9, e100393, 10.1371/journal.pone.0100393 Gipson, 2011, Comparison of mucin levels at the ocular surface of postmenopausal women with and without a history of dry eye, Cornea, 30, 1346, 10.1097/ICO.0b013e31820d852a Brockhausen, 1995, Mechanisms underlying aberrant glycosylation of MUC1 mucin in breast cancer cells, Eur J Biochem, 233, 607, 10.1111/j.1432-1033.1995.607_2.x Ohtsubo, 2006, Glycosylation in cellular mechanisms of health 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the pancreas, J Clin Pathol, 58, 845, 10.1136/jcp.2004.023572 Wang, 2011, Detection of the potential pancreatic cancer marker MUC4 in serum using surface-enhanced Raman scattering, Anal Chem, 83, 2554, 10.1021/ac102829b Chaturvedi, 2008, Structure, evolution, and biology of the MUC4 mucin, FASEB J, 22, 966, 10.1096/fj.07-9673rev Ordonez, 2001, Mild and moderate asthma is associated with airway goblet cell hyperplasia and abnormalities in mucin gene expression, Am J Respir Crit Care Med, 163, 517, 10.1164/ajrccm.163.2.2004039 Carraway, 2007, Contribution of membrane mucins to tumor progression through modulation of cellular growth signaling pathways, Curr Top Dev Biol, 78, 1, 10.1016/S0070-2153(06)78001-2 O'Brien, 2002, The CA 125 gene: a newly discovered extension of the glycosylated N-terminal domain doubles the size of this extracellular superstructure, Tumour Biol, 23, 154, 10.1159/000064032 Maeda, 2004, Solution structure of the SEA domain from the murine homologue of ovarian 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