Changes in the distribution of endothelial surface glycoconjugates associated with altered permeability of brain micro-blood vessels

A Vorbrodt1
1Institute for Basic Research in Developmental Disabilities, Staten Island, USA

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Betz AL, Goldstein GW (1978) Polarity of the blood-brain barrier: neutral amino acid transport into isolated brain capillaries. Science 202:225?227

Betz AL, Firth TA, Goldstein GW (1980) Polarity of the blood-brain barrier: distribution of enzymes between the luminal and antiluminal membranes of brain capillary endothelial cells. Brain Res 192:17?28

Frens G (1973) Controlled nucleation for the regulation of the particle size in monodisperse gold suspensions. Nat Phys Sci 241:20?22

Hughes RC (1976) Membrane glycoproteins. A review of structure and function. Butterworths, London, pp 1?5

Lucocq JM, Roth J (1984) Application of immunocolloids in light microscopy. III. Demonstration of antigenic and lectin-binding sites in semithin resin sections. J Histochem Cytochem 32:1075?1083

Nag S (1985) Alteration of surface charge on cerebral endothelium in acute hypertension. J Neuropathol Exp Neurol 42:339 [Abstr]

Nag S (1985) Ultrastructural localization of lectin receptors on cerebral endothelium. Acta Neuropathol (Berl) 66:105?110

Nag S, Arseneau R (1983) Alteration of endothelial surface charge in hypertension. J Cereb Blood Flow Metabol [Suppl] 3:24?25

Palade GE, Simionescu M, Simionescu N (1982). Differentiated microdomains in the vascular endothelium. In: Nossel HL, Vogel HJ (eds) Pathobiology of the endothelial cell. Academic Press, New York London, pp 23?33

Pino RM (1984) Ultrastructural localization of lectin receptors on the bone-marrow sinusoidal endothelium of the rat. Am J Anat 169:259?272

Roth J (1983) Application of lectin-gold complexes for electron microscopic localization of glycoconjugates on thin sections. J Histochem Cytochem 31:987?999

Roth J (1984) Cytochemical localization of terminalN-acetyl-d-galactosamine residues in cellular compartments of intestinal goblet cells: implications for the topology ofO-glycosylation. J Cell Biol 98:399?406

Roth J, Lucocq JM, Charest PM (1984) Light and electron microscopic demonstration of sialic acid residues with the lectin fromLimax flavus: a cytochemical affinity technique with the use of fetnin-gold complexes. J Histochem Cytochem 32:1167?1176

Schulte BA, Spicer SS (1985) Histochemical methods for characterizing secretory and cell surface sialoglycoconjugates. J Histochem Cytochem 33:427?438

Simionescu N, Simionescu M, Palade GE (1981) Differentiated microdomains on the luminal surface of the capillary endothelium. I. Preferential distribution of anionic sites. J Cell Biol 90:605?613

Simionescu M, Simionescu N,Silbert JE, Palade GE (1981) Differentiated microdomains on the luminal surface of the capillary endothelium. II. Partial characterization of their anionic sites. J Cell Biol 90:614?621

Simionescu M, Simionescu N, Palade GE (1982) Differentiated microdomains on the luminal surface of the capillary endothelium: distribution of lectin receptors. J Cell Biol 94:406?413

Simionescu M, Simionescu N, Palade GE (1982) Preferential distribution of anionic sites on the basement membrane and the abluminal aspect of the endothelium in fenestrated capillaries. J Cell Biol 95:425?434

Skutelsky E, Danon D (1976) Redistribution of surface anionic sites on the luminal front of blood vessel endothelium after interaction with polycationic ligand. J Cell Biol 71:232?241

Skutelsky E, Farquhar MG (1976) Variations in distribution of Con A-receptor sites and anionic groups during red blood cell differentiation in the rat. J Cell Biol 71:218?231

Soda R, Tavassoli M (1983) Mapping of the bone marrow sinus endothelium with lectins and glycosylated ferritins: identification of differentiated microdomains and their functional significance. J Ultrastruct Res 84:299?310

Van Deurs B (1977) Vesicular transport of horseradish peroxidase from brain to blood in segments of the cerebral microvasculature in adult mice. Brain Res 124:1?8

Vorbrodt AW, Lossinsky AS, Wisniewski HM (1983) Enzyme cytochemistry of blood-brain barrier (BBB) disturbances. Acta Neuropathol [Suppl] (Berl) VIII:43?57

Vorbrodt AW, Lossinsky AS, Wisniewski HM (1984) Ultrastructural studies of concanavalin A receptors and 5?-nucleotidase localization in normal and injured mouse cerebral microvasculature. Acta Neuropathol (Berl) 63: 210?217

Vorbrodt AW, Lossinsky AS, Wisniewski HM, Suzuki R, Yamaguchi T, Masaoka H, Klatzo I (1985) Ultrastructural observations on the transvascular route of protein removal in vasogenic brain edema. Acta Neuropathol (Berl) 66: 265?273

Vorbrodt AW, Dobrogowska DH, Lossinsky AS, Wisniewski HM (1986) Ultrastructural localization of lectin receptors on the luminal and abluminal aspects of brain micro-blood vessels. J Histochem Cytochem (in press)