Hepatocellular Carcinoma: An Unusual Complication of Longstanding Wilson Disease

Ala, 2007, Wilson's disease, Lancet, 369, 397, 10.1016/S0140-6736(07)60196-2 Bandmann, 2015, Wilson's disease and other neurological copper disorders, Lancet Neurol, 14, 103, 10.1016/S1474-4422(14)70190-5 Frydman, 1990, Genetic aspects of Wilson's disease, J Gastroenterol Hepatol, 5, 483, 10.1111/j.1440-1746.1990.tb01427.x Sauer, 2011, Severe dysfunction of respiratory chain and cholesterol metabolism in Atp7b−/− mice as a model for Wilson disease, Biochim Biophys Acta, 1812, 1607, 10.1016/j.bbadis.2011.08.011 Zischka, 2011, Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease, J Clin Investig, 121, 1508, 10.1172/JCI45401 Roberts, 2008, Diagnosis and treatment of Wilson disease: an update, Hepatology, 47, 2089, 10.1002/hep.22261 van Meer, 2015, No increased risk of hepatocellular carcinoma in cirrhosis due to Wilson disease during long-term follow-up, J Gastroenterol Hepatol, 30, 535, 10.1111/jgh.12716 Pfeiffenberger, 2015, Hepatobiliary malignancies in Wilson disease, Liver Int, 35, 1615, 10.1111/liv.12727 Walshe, 2003, Abdominal malignancies in patients with Wilson's disease, QJM, 96, 657, 10.1093/qjmed/hcg114 Kato, 1996, Hepatic iron deprivation prevents spontaneous development of fulminant hepatitis and liver cancer in Long-Evans Cinnamon rats, J Clin Investig, 98, 923, 10.1172/JCI118875 Medici, 2007, Effect of penicillamine and zinc on iron metabolism in Wilson's disease, Scand J Gastroenterol, 42, 1495, 10.1080/00365520701514495 Sheline, 2011, Thiamine supplementation attenuated hepatocellular carcinoma in the Atp7b mouse model of Wilson's disease, Anticancer Res, 31, 3395