Aurora B Phosphorylates Spatially Distinct Targets to Differentially Regulate the Kinetochore-Microtubule Interface

Molecular Cell - Tập 38 - Trang 383-392 - 2010
Julie P.I. Welburn1,2, Mathijs Vleugel1,2, Dan Liu3, John R. Yates4, Michael A. Lampson3, Tatsuo Fukagawa5, Iain M. Cheeseman1,2
1Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA
2Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA
3Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA
4Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
5Department of Molecular Genetics, National Institute of Genetics and The Graduate University for Advanced Studies (SOKENDAI), Mishima, Shizuoka 411-8540, Japan

Tài liệu tham khảo

Akiyoshi, 2009, Analysis of Ipl1-mediated phosphorylation of the Ndc80 kinetochore protein in Saccharomyces cerevisiae, Genetics, 183, 1591, 10.1534/genetics.109.109041 Cantin, 2004, Strategies for shotgun identification of post-translational modifications by mass spectrometry, J. Chromatogr. A, 1053, 7, 10.1016/S0021-9673(04)00971-9 Cheeseman, 2008, Molecular architecture of the kinetochore-microtubule interface, Nat. Rev. Mol. Cell Biol., 9, 33, 10.1038/nrm2310 Cheeseman, 2006, The conserved KMN network constitutes the core microtubule-binding site of the kinetochore, Cell, 127, 983, 10.1016/j.cell.2006.09.039 Cheeseman, 2008, KNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebrates, Mol. Biol. Cell, 19, 587, 10.1091/mbc.e07-10-1051 Ciferri, 2008, Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex, Cell, 133, 427, 10.1016/j.cell.2008.03.020 DeLuca, 2006, Kinetochore microtubule dynamics and attachment stability are regulated by Hec1, Cell, 127, 969, 10.1016/j.cell.2006.09.047 Emanuele, 2008, Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly, J. Cell Biol., 181, 241, 10.1083/jcb.200710019 Fukagawa, 2001, CENP-H, a constitutive centromere component, is required for centromere targeting of CENP-C in vertebrate cells, EMBO J., 20, 4603, 10.1093/emboj/20.16.4603 Guimaraes, 2008, Kinetochore-microtubule attachment relies on the disordered N-terminal tail domain of Hec1, Curr. Biol., 18, 1778, 10.1016/j.cub.2008.08.012 Hauf, 2003, The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint, J. Cell Biol., 161, 281, 10.1083/jcb.200208092 Hori, 2003, Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells, J. Cell Sci., 116, 3347, 10.1242/jcs.00645 Kemmler, 2009, Mimicking Ndc80 phosphorylation triggers spindle assembly checkpoint signalling, EMBO J., 28, 1099, 10.1038/emboj.2009.62 Kline, 2006, The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation, J. Cell Biol., 173, 9, 10.1083/jcb.200509158 Lampson, 2004, Correcting improper chromosome-spindle attachments during cell division, Nat. Cell Biol., 6, 232, 10.1038/ncb1102 Liu, 2009, Sensing chromosome bi-orientation by spatial separation of Aurora B kinase from kinetochore substrates, Science, 323, 1350, 10.1126/science.1167000 Miller, 2008, Kinetochore attachments require an interaction between unstructured tails on microtubules and Ndc80(Hec1), Curr. Biol., 18, 1785, 10.1016/j.cub.2008.11.007 Nash, 2001, Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication, Nature, 414, 514, 10.1038/35107009 Pinsky, 2006, The Ipl1-Aurora protein kinase activates the spindle checkpoint by creating unattached kinetochores, Nat. Cell Biol., 8, 78, 10.1038/ncb1341 Ruchaud, 2007, Chromosomal passengers: conducting cell division, Nat. Rev. Mol. Cell Biol., 8, 798, 10.1038/nrm2257 Tanaka, 2002, Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections, Cell, 108, 317, 10.1016/S0092-8674(02)00633-5 Wan, 2009, Protein architecture of the human kinetochore microtubule attachment site, Cell, 137, 672, 10.1016/j.cell.2009.03.035 Washburn, 2001, Large-scale analysis of the yeast proteome by multidimensional protein identification technology, Nat. Biotechnol., 19, 242, 10.1038/85686 Wei, 2007, The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment, Nat. Struct. Mol. Biol., 14, 54, 10.1038/nsmb1186 Welburn, 2008, Toward a molecular structure of the eukaryotic kinetochore, Dev. Cell, 15, 645, 10.1016/j.devcel.2008.10.011 Yang, 2008, Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore, J. Biol. Chem., 283, 26726, 10.1074/jbc.M804207200