Synthesis of 2,4,5-trisubstituted imidazoles catalyzed by [Hmim]HSO4 as a powerful Brönsted acidic ionic liquid

Canadian Science Publishing - Tập 86 Số 3 - Trang 264-269 - 2008
Ahmad Reza Khosropour

Tóm tắt

An efficient and green procedure for the synthesis of 2,4,5-trisubstituted imidazoles with various aldehydes using a catalytic amount of 1-methylimidazolium hydrogenesulfate as an active and low cost Brönsted acidic room temperature ionic liquid has been developed. The ionic liquid was easily separated from the reaction mixture and was recycled five times without any loss in activity.Key words: ionic liquid, 2,4,5-trisubstituted imidazoles, [Hmim]HSO4, aldehyde, benzil.

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