Stress myocardial perfusion single-photon emission computed tomography is clinically effective and cost effective in risk stratification of patients with a high likelihood of coronary artery disease (CAD) but no known CAD

Diamond, 1983, Computer-assisted diagnosis in the noninvasive evaluation of patients with suspected coronary artery disease, J Am Coll Cardiol, 1, 444, 10.1016/S0735-1097(83)80072-2 Scanlon, 1999, ACC/AHA guidelines for coronary angiography, J Am Coll Cardiol, 33, 1756, 10.1016/S0735-1097(99)00126-6 Gibbons, 1999, ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina, J Am Coll Cardiol, 33, 2092, 10.1016/S0735-1097(99)00150-3 Gibbons, 1997, ACC/AHA guidelines for exercise testing, J Am Coll Cardiol, 30, 260 Ritchie, 1995, Guidelines for clinical use of cardiac radionuclide imaging, J Am Coll Cardiol, 25, 521, 10.1016/0735-1097(95)90027-6 Kaul, 1988, Prognostic utility of the exercise thallium-201 test in ambulatory patients with chest pain, Circulation, 77, 745, 10.1161/01.CIR.77.4.745 Marie, 1995, Long-term prediction of major ischemic events by exercise thallium-201 single-photon emission computed tomography, J Am Coll Cardiol, 26, 879, 10.1016/0735-1097(95)00243-9 Mattera, 1998, Exercise testing with myocardial perfusion imaging in patients with normal baseline electrocardiograms, J Nucl Cardiol, 5, 498, 10.1016/S1071-3581(98)90181-7 Pollock, 1992, Independent and incremental prognostic value of tests performed in hierarchical order to evaluate patients with suspected coronary artery disease, Circulation, 85, 237, 10.1161/01.CIR.85.1.237 Stratmann, 1994, Exercise technetium-99m sestamibi tomography for cardiac risk stratification of patients with stable chest pain, Circulation, 89, 615, 10.1161/01.CIR.89.2.615 Bairey, 1989, Exercise thallium-201 scintigraphy and prognosis in typical angina pectoris and negative exercise electrocardiography, Am J Cardiol, 64, 282, 10.1016/0002-9149(89)90520-1 Hachamovitch, 1996, Exercise myocardial perfusion SPECT in patients without known coronary artery disease, Circulation, 93, 905, 10.1161/01.CIR.93.5.905 Ladenheim, 1987, Incremental prognostic power of clinical history, exercise electrocardiography and myocardial perfusion scintigraphy in suspected coronary artery disease, Am J Cardiol, 59, 270, 10.1016/0002-9149(87)90798-3 Staniloff, 1986, Prediction of death, myocardial infarction, and worsening chest pain using thallium scintigraphy and exercise electrocardiography, J Nucl Med, 27, 1842 Berman, 1993, Separate acquisition rest thallium-201/stress technetium-99m sestamibi dual-isotope myocardial perfusion single-photon emission computed tomography, J Am Coll Cardiol, 22, 1455, 10.1016/0735-1097(93)90557-H Mark, 1987, Exercise treadmill score for predicting prognosis in coronary artery disease, Ann Intern Med, 106, 793, 10.7326/0003-4819-106-6-793 Hachamovitch, 1995, Gender-related differences in clinical management after exercise nuclear testing, J Am Coll Cardiol, 26, 1457, 10.1016/0735-1097(95)00356-8 Ladenheim, 1986, Extent and severity of myocardial hypoperfusion as predictors of prognosis in patients with suspected coronary artery disease, J Am Coll Cardiol, 7, 464, 10.1016/S0735-1097(86)80454-5 Cox, 1972, Regression models and life tables (with discussion), J R Stat Soc Ser B Methodol, 34, 187 Greenland, 1989, Modeling and variable selection in epidemiologic analysis, Am J Public Health, 79, 340, 10.2105/AJPH.79.3.340 Harrell, 1996, Multivariable prognostic models, Stat Med, 15, 361, 10.1002/(SICI)1097-0258(19960229)15:4<361::AID-SIM168>3.0.CO;2-4 Hachamovitch, 2002, Value of stress myocardial perfusion single photon emission computed tomography in patients with normal resting electrocardiograms, Circulation, 105, 823, 10.1161/hc0702.103973 Christian, 1994, Exercise tomographic thallium-201 imaging in patients with severe coronary artery disease and normal electrocardiograms, Ann Intern Med, 121, 825, 10.7326/0003-4819-121-11-199412010-00001 Berman, 1995, Incremental value of prognostic testing in patients with known or suspected ischemic heart disease, J Am Coll Cardiol, 26, 639, 10.1016/0735-1097(95)00218-S Hachamovitch, 2003, Determinants of risk and its temporal variation in patients with normal stress myocardial perfusion scans, J Am Coll Cardiol, 41, 1329, 10.1016/S0735-1097(03)00125-6 Matching the intensity of risk factor management with the hazard for coronary disease events. Presented at the 27th Bethesda Conference, September 14–15, 1995. J Am Coll Cardiol 1996;27:957–1047 Califf, 1996, Task Force 5, J Am Coll Cardiol, 27, 1007, 10.1016/0735-1097(96)87733-3 Hachamovitch, 2000, Methodological considerations in the assessment of noninvasive testing using outcomes research, Prog Cardiovasc Dis, 43, 215, 10.1053/pcad.2000.19313 Berman DS, Germano G, Shaw LJ. Nuclear cardiology. In: Fuster V, Alexander R, King S, O'Rourke RA, Wellens HJJ, editors. Hurst's The Heart. New York, NY: McGraw-Hill, 2000:525–65 Van Train, 1994, Multicenter trial validation for quantitative analysis of same-day rest-stress technetium-99m-sestamibi myocardial tomograms, J Nucl Med, 35, 609 Berman, 1998, Comparative prognostic value of automatic quantitative analysis versus semiquantitative visual analysis of exercise myocardial perfusion single-photon emission computed tomography, J Am Coll Cardiol, 32, 1987, 10.1016/S0735-1097(98)00501-4