The ice nucleation temperature determines the primary drying rate of lyophilization for samples frozen on a temperature‐controlled shelf

Journal of Pharmaceutical Sciences - Tập 90 - Trang 860-871 - 2001
James A. Searles1,2, John F. Carpenter3, Theodore W. Randolph1
1Center for Pharmaceutical Biotechnology and Department of Chemical Engineering, University of Colorado, Boulder, Colorado 80309
2Vaccine Technology and Engineering, Merck & Company, Inc., West Point, Pennsylvania 19486
3Center for Pharmaceutical Biotechnology and Department of Pharmaceutical Sciences, School of Pharmacy, University of Colorado Health Sciences Center, Denver, Colorado 80262

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Journal of Pharmaceutical Sciences

Tập 90

860-871

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