Knockdown of cZNF292 suppressed hypoxic human hepatoma SMMC7721 cell proliferation, vasculogenic mimicry, and radioresistance

Cellular Signalling - Tập 60 - Trang 122-135 - 2019
Wei Yang1, Yingying Liu1,2, Ruoling Gao1, Zenghe Xiu1, Ting Sun3,4
1State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, Jiangsu, China
2Isotopic Laboratory of Nuclear Medicine, Xi'an Central Hospital, Xi'an, Shaanxi, China
3Neurosurgery and Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
4Division of Surgical Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

Tài liệu tham khảo

Mcglynn, 2015, Global epidemiology of hepatocellular carcinoma: an emphasis on demographic and regional variability, Clinics in Liver Disease, 19, 223, 10.1016/j.cld.2015.01.001 2017, The burden of primary liver Cancer and underlying etiologies from 1990 to 2015 at the global, regional, and National Level: results from the global burden of disease study 2015, JAMA Oncology, 3, 1683, 10.1001/jamaoncol.2017.3055 Okushin, 2018, Helicobacter pylori infection and liver diseases: epidemiology and insights into pathogenesis, World Journal of Gastroenterology, 24, 3617, 10.3748/wjg.v24.i32.3617 DiStefano, 2017, Long noncoding RNAs in the initiation, progression, and metastasis of hepatocellular carcinoma, Noncoding RNA Res., 2, 129, 10.1016/j.ncrna.2017.11.001 Pavel, 2018, Expansion of the hepatocellular carcinoma Milan criteria in liver transplantation: future directions, World Journal of Gastroenterology, 24, 3626, 10.3748/wjg.v24.i32.3626 Lau, 2008, Hepatocellular carcinoma. Current management and recent advances, Hepatobiliary & Pancreatic Diseases International, 7, 237 Harris, 2002, Hypoxia--a key regulatory factor in tumour growth, Nature Reviews. Cancer, 2, 38, 10.1038/nrc704 Wilde, 2017, Metabolic coupling and the reverse Warburg effect in cancer: implications for novel biomarker and anticancer agent development, Seminars in Oncology, 44, 198, 10.1053/j.seminoncol.2017.10.004 Semenza, 2003, Targeting HIF-1 for cancer therapy, Nature Reviews. Cancer, 3, 721, 10.1038/nrc1187 Laitala, 2018, Hypoxic Signalling in tumour stroma, Frontiers in Oncology, 8, 189, 10.3389/fonc.2018.00189 Choudhry, 2018, Advances in hypoxia-inducible factor biology, Cell Metabolism, 27, 281, 10.1016/j.cmet.2017.10.005 Grimes, 2017, Hypoxia imaging and radiotherapy: bridging the resolution gap, The British Journal of Radiology, 90, 10.1259/bjr.20160939 Horsman, 2012, Imaging hypoxia to improve radiotherapy outcome, Nature Reviews. Clinical Oncology, 9, 674, 10.1038/nrclinonc.2012.171 Rey, 2017, Molecular targeting of hypoxia in radiotherapy, Advanced Drug Delivery Reviews, 109, 45, 10.1016/j.addr.2016.10.002 Sun, 2018, Emerging role of exosome-derived long non-coding RNAs in tumor microenvironment, Molecular Cancer, 17, 82, 10.1186/s12943-018-0831-z Liu, 2018, Nuclear functions of mammalian MicroRNAs in gene regulation, immunity and cancer, Molecular Cancer, 17, 64, 10.1186/s12943-018-0765-5 Hou, 2018, Circular RNAs and exosomes in cancer: a mysterious connection, Clin. Transl.Oncol., 20, 1109, 10.1007/s12094-018-1839-y Xin, 2017, The understanding of circular RNAs as special triggers in carcinogenesis, Briefings in Functional Genomics, 16, 80 Li, 2015, Circular RNAs in cancer: novel insights into origins, properties, functions and implications, American Journal of Cancer Research, 5, 472 Conn, 2015, The RNA binding protein quaking regulates formation of circRNAs, Cell, 160, 1125, 10.1016/j.cell.2015.02.014 Cui, 2018, Emerging function and potential diagnostic value of circular RNAs in cancer, Molecular Cancer, 17, 123, 10.1186/s12943-018-0877-y Memczak, 2013, Circular RNAs are a large class of animal RNAs with regulatory potency, Nature, 495, 333, 10.1038/nature11928 Wang, 2016, Circular RNAs as potential biomarkers for cancer diagnosis and therapy, American Journal of Cancer Research, 6, 1167 He, 2017, Circular RNAs and cancer, Cancer Letters, 396, 138, 10.1016/j.canlet.2017.03.027 Kristensen, 2018, Circular RNAs in cancer: opportunities and challenges in the field, Oncogene, 37, 555, 10.1038/onc.2017.361 Boeckel, 2015, Identification and characterization of hypoxia-regulated endothelial circular RNA, Circulation Res, 117, 884, 10.1161/CIRCRESAHA.115.306319 Yang, 2018, HDAC6 inhibition induces glioma stem cells differentiation and enhances cellular radiation sensitivity through the SHH/Gli1 signaling pathway, Cancer Letters, 415, 164, 10.1016/j.canlet.2017.12.005 Du, 2017, Foxo3 circular RNA promotes cardiac senescence by modulating multiple factors associated with stress and senescence responses, European Heart Journal, 38, 1402 Du, 2016, Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2, Nucleic Acids Research, 44, 2846, 10.1093/nar/gkw027 Liu, 2018, In vitro and in vivo apatinib inhibits vasculogenic mimicry in melanoma MUM2B cells, PLoS One, 13 Trautmann, 2014, SS18-SSX fusion protein-induced Wnt/β-catenin signaling is a therapeutic target in synovial sarcoma, Oncogene, 33, 5006, 10.1038/onc.2013.443 Mao, 2017, UBR2 enriched in p53 deficient mouse bone marrow mesenchymal stem cell-exosome promoted gastric Cancer progression via Wnt/β-catenin pathway, Stem Cells, 35, 2267, 10.1002/stem.2702 Yang, 2016, Silencing of cZNF292 circular RNA suppresses human glioma tube formation via the Wnt/β-catenin signaling pathway, Oncotarget, 7, 63449, 10.18632/oncotarget.11523 Liu, 2015, Hypoxia induced epithelial-mesenchymal transition and vasculogenic mimicry formation by promoting Bcl-2/Twist1 cooperation, Experimental and Molecular Pathology, 99, 383, 10.1016/j.yexmp.2015.08.009 Georg, 2014, Endothelial cadherins in cancer, Cell and Tissue Research, 355, 523, 10.1007/s00441-014-1851-7 Qi, 2015, Wnt3a promotes the Vasculogenic mimicry formation of Colon Cancer via Wnt/β-catenin signaling, International Journal of Molecular Sciences, 16, 18564, 10.3390/ijms160818564 Qi, 2014, Wnt3a expression is associated with epithelial-mesenchymal transition and promotes colon cancer progression, Journal of Experimental & Clinical Cancer Research, 33, 107, 10.1186/s13046-014-0107-4 Cui, 2015, The involvement of c-Myc in the DNA double-strand break repair via regulating radiation-induced phosphorylation of ATM and DNA-PKcs activity, Molecular and Cellular Biochemistry, 406, 43, 10.1007/s11010-015-2422-2 Chan, 1996, The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit, The Journal of Biological Chemistry, 271, 8936, 10.1074/jbc.271.15.8936 Akiyama, 2004, Interactions between Sox9 and beta-catenin control chondrocyte differentiation, Genes & Development, 18, 1072, 10.1101/gad.1171104 Bernard, 2010, Acquisition of SOX transcription factor specificity through protein-protein interaction, modulation of Wnt signalling and post-translational modification, The International Journal of Biochemistry & Cell Biology, 42, 400, 10.1016/j.biocel.2009.10.017 Lin, 2018, Long non-coding RNA UBE2CP3 enhances HCC cell secretion of VEGFA and promotes angiogenesis by activating ERK1/2/HIF-1α/VEGFA signalling in hepatocellular carcinoma, Journal of Experimental & Clinical Cancer Research, 37, 113, 10.1186/s13046-018-0727-1 Xiong, 2017, Advances in hypoxia-mediated mechanisms in hepatocellular carcinoma, Molecular Pharmacology, 92, 246, 10.1124/mol.116.107706 Ewing, 1998, The oxygen fixation hypothesis: a reevaluation, American Journal of Clinical Oncology, 21, 355, 10.1097/00000421-199808000-00008 Grimes, 2015, A mechanistic investigation of the oxygen fixation hypothesis and oxygen enhancement ratio, Biomed. Phys. Eng. Express, 1, 045209, 10.1088/2057-1976/1/4/045209 Mistry, 2017, Clinical advances of hypoxia-activated prodrugs in combination with radiation therapy, International Journal of Radiation Oncology, Biology, Physics, 98, 1183, 10.1016/j.ijrobp.2017.03.024 Harada, 2011, How can we overcome tumor hypoxia in radiation therapy?, Journal of Radiation Research, 52, 545, 10.1269/jrr.11056 Yang, 2012, Downregulation of miR-210 expression inhibits proliferation, induces apoptosis and enhances radiosensitivity in hypoxic human hepatoma cells in vitro, Experimental Cell Research, 318, 944, 10.1016/j.yexcr.2012.02.010 Liu, 2015, Cellular and molecular mechanisms underlying oxygen-dependent radiosensitivity, Radiation Research, 183, 487, 10.1667/RR13959.1 Rankin, 2016, Hypoxic control of metastasis, Science, 352, 175, 10.1126/science.aaf4405 Bahn, 2015, The landscape of microRNA, Piwi-interacting RNA, and circular RNA in human saliva, Clinical Chemistry, 61, 221, 10.1373/clinchem.2014.230433 Li, 2015, Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis, Cell Research, 25, 981, 10.1038/cr.2015.82 Dong, 2016, Identification and characterization of human testis derived circular RNAs and their existence in seminal plasma, Scientific Reports, 6, 39080, 10.1038/srep39080 Wang, 2017, Circular RNA in cardiovascular disease, Non-coding. RNA Investig., 1, 5, 10.21037/ncri.2017.08.04 Liu, 2013, Mechano-regulation of alternative splicing, Current Genomics, 14, 49 Boeckel, 2011, Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1, Proceedings of the National Academy of Sciences of the United States of America, 108, 3276, 10.1073/pnas.1008098108