Neuroprotective pathways: lifestyle activity, brain pathology, and cognition in cognitively normal older adults

Neurobiology of Aging - Tập 35 - Trang 1873-1882 - 2014
Miranka Wirth1, Claudia M. Haase2, Sylvia Villeneuve1, Jacob Vogel1, William J. Jagust1,3,4
1Helen Wills Neuroscience Institute, University of California, Berkeley, CA USA
2School of Education and Social Policy, Northwestern University, Evanston, IL, USA
3Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA
4School of Public Health, University of California, Berkeley, CA, USA

Tài liệu tham khảo

Aizenstein, 2008, Frequent amyloid deposition without significant cognitive impairment among the elderly, Arch. Neurol., 65, 1509, 10.1001/archneur.65.11.1509 Arenaza-Urquijo, 2013, Relationships between years of education and gray matter volume, metabolism and functional connectivity in healthy elders, Neuroimage, 83C, 450, 10.1016/j.neuroimage.2013.06.053 Barnes, 2011, The projected effect of risk factor reduction on Alzheimer's disease prevalence, Lancet Neurol., 10, 819, 10.1016/S1474-4422(11)70072-2 Bentler, 1987, Practical issues in structural modeling, Sociol. Methods Res., 16, 78, 10.1177/0049124187016001004 Bero, 2011, Neuronal activity regulates the regional vulnerability to amyloid-beta deposition, Nat. Neurosci., 14, 750, 10.1038/nn.2801 Bollen, 1993 Braak, 2011, Stages of the pathologic process in Alzheimer disease: age categories from 1 to 100 years, J. Neuropathol. Exp. Neurol., 70, 960, 10.1097/NEN.0b013e318232a379 Brody, 2008, Amyloid-beta dynamics correlate with neurological status in the injured human brain, Science, 321, 1221, 10.1126/science.1161591 Byrne, 1998 Cardenas, 2012, Associations among vascular risk factors, carotid atherosclerosis, and cortical volume and thickness in older adults, Stroke, 43, 2865, 10.1161/STROKEAHA.112.659722 Carlson, 2008, Midlife activity predicts risk of dementia in older male twin pairs, Alzheimers Dement., 4, 324, 10.1016/j.jalz.2008.07.002 Christensen, 1996, Activity levels and cognitive functioning in an elderly community sample, Age Ageing, 25, 72, 10.1093/ageing/25.1.72 Conover, 1981, Rank transformations as a bridge between parametric and nonparametric statistics, Am. Stat., 35, 124 Conover, 1982, Analysis of covariance using the rank transformation, Biometrics, 38, 715, 10.2307/2530051 Costa, 2007, Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms, Neurobiol. Aging, 28, 831, 10.1016/j.neurobiolaging.2006.04.009 Dale, 1999, Cortical surface-based analysis. I. Segmentation and surface reconstruction, Neuroimage, 9, 179, 10.1006/nimg.1998.0395 de Groot, 2013, Changes in normal-appearing white matter precede development of white matter lesions, Stroke, 44, 1037, 10.1161/STROKEAHA.112.680223 DeCarli, 2005, Anatomical mapping of white matter hyperintensities (WMH): exploring the relationships between periventricular WMH, deep WMH, and total WMH burden, Stroke, 36, 50, 10.1161/01.STR.0000150668.58689.f2 Desikan, 2012, Amyloid-beta-associated clinical decline occurs only in the presence of elevated p-tau, Arch. Neurol., 69, 709, 10.1001/archneurol.2011.3354 Desikan, 2006, An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest, Neuroimage, 31, 968, 10.1016/j.neuroimage.2006.01.021 Dickerson, 2009, The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals, Cereb. Cortex, 19, 497, 10.1093/cercor/bhn113 Erickson, 2010, Physical activity predicts gray matter volume in late adulthood: the Cardiovascular Health Study, Neurology, 75, 1415, 10.1212/WNL.0b013e3181f88359 Erickson, 2011, Exercise training increases size of hippocampus and improves memory, Proc. Natl. Acad. Sci. U.S.A, 108, 3017, 10.1073/pnas.1015950108 Ewers, 2011, Neuroimaging markers for the prediction and early diagnosis of Alzheimer's disease dementia, Trends Neurosci., 34, 430, 10.1016/j.tins.2011.05.005 Fischl, 2000, Measuring the thickness of the human cerebral cortex from magnetic resonance images, Proc. Natl. Acad. Sci. U.S.A, 97, 11050, 10.1073/pnas.200033797 Fischl, 2002, Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain, Neuron, 33, 341, 10.1016/S0896-6273(02)00569-X Fischl, 1999, Cortical surface-based analysis. II: inflation, flattening, and a surface-based coordinate system, Neuroimage, 9, 195, 10.1006/nimg.1998.0396 Floel, 2010, Physical activity and memory functions: are neurotrophins and cerebral gray matter volume the missing link?, Neuroimage, 49, 2756, 10.1016/j.neuroimage.2009.10.043 Folstein, 1975, “Mini-mental state”: a practical method for grading the cognitive state of patients for the clinicians, J. Psychiatr. Res., 12, 189, 10.1016/0022-3956(75)90026-6 Friedland, 2001, Patients with Alzheimer's disease have reduced activities in midlife compared with healthy control-group members, Proc. Natl. Acad. Sci. U.S.A, 98, 3440, 10.1073/pnas.061002998 Geffken, 2001, Association between physical activity and markers of inflammation in a healthy elderly population, Am. J. Epidemiol., 153, 242, 10.1093/aje/153.3.242 Gold, 2013, Lifelong bilingualism maintains neural efficiency for cognitive control in aging, J. Neurosci., 33, 387, 10.1523/JNEUROSCI.3837-12.2013 Gons, 2013, Physical activity is related to the structural integrity of cerebral white matter, Neurology, 81, 971, 10.1212/WNL.0b013e3182a43e33 Gow, 2012, Neuroprotective lifestyles and the aging brain: activity, atrophy, and white matter integrity, Neurology, 79, 1802, 10.1212/WNL.0b013e3182703fd2 Hauser, 1997, Socioeconomic indexes for occupations: a review, update, and critique, Sociological Methodol., 27, 177, 10.1111/1467-9531.271028 Hayes, A.F. 2013. Introduction to mediation, moderation, and conditional process analysis: a regression-based approach. Hayes, 2013, The relative trustworthiness of inferential tests of the indirect effect in statistical mediation analysis: does method really matter?, Psychol. Sci., 24, 1918, 10.1177/0956797613480187 Hedden, 2012, Cognitive profile of amyloid burden and white matter hyperintensities in cognitively normal older adults, J. Neurosci., 32, 16233, 10.1523/JNEUROSCI.2462-12.2012 Hedden, 2013, Meta-analysis of amyloid-cognition relations in cognitively normal older adults, Neurology, 80, 1341, 10.1212/WNL.0b013e31828ab35d Hedden, 2012, Failure to modulate attentional control in advanced aging linked to white matter pathology, Cereb. Cortex, 22, 1038, 10.1093/cercor/bhr172 Herring, 2011, Preventive and therapeutic types of environmental enrichment counteract beta amyloid pathology by different molecular mechanisms, Neurobiol. Dis., 42, 530, 10.1016/j.nbd.2011.03.007 Hertzog, 2008, Enrichment effects on adult cognitive development: can the functional capacity of older adults be preserved and enhanced?, Psychol. Sci. Public Interest, 9, 1, 10.1111/j.1539-6053.2009.01034.x Ho, 2011, The effects of physical activity, education, and body mass index on the aging brain, Hum. Brain Mapp., 32, 1371, 10.1002/hbm.21113 Hultsch, 1993, Age differences in cognitive performance in later life: relationships to self-reported health and activity life style, J. Gerontol., 48, P1, 10.1093/geronj/48.1.P1 Hultsch, 1999, Use it or lose it: engaged lifestyle as a buffer of cognitive decline in aging?, Psychol. Aging, 14, 245, 10.1037/0882-7974.14.2.245 Jack, 2010, Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade, Lancet Neurol., 9, 119, 10.1016/S1474-4422(09)70299-6 Jack, 2012, An operational approach to National Institute on Aging-Alzheimer's Association criteria for preclinical Alzheimer disease, Ann. Neurol., 71, 765, 10.1002/ana.22628 Jagust, 2011, Lifespan brain activity, beta-amyloid, and Alzheimer's disease, Trends Cogn. Sci., 15, 520, 10.1016/j.tics.2011.09.004 Joshi, 2009, Reducing between scanner differences in multi-center PET studies, Neuroimage, 46, 154, 10.1016/j.neuroimage.2009.01.057 Kang, 2009, Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle, Science, 326, 1005, 10.1126/science.1180962 Kivipelto, 2001, Midlife vascular risk factors and late-life mild cognitive impairment: a population-based study, Neurology, 56, 1683, 10.1212/WNL.56.12.1683 Klunk, 2004, Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B, Ann. Neurol., 55, 306, 10.1002/ana.20009 Knopman, 2013, Brain injury biomarkers are not dependent on beta-amyloid in normal elderly, Ann. Neurol., 73, 472, 10.1002/ana.23816 Kok, 2009, Apolipoprotein E-dependent accumulation of Alzheimer disease-related lesions begins in middle age, Ann. Neurol., 65, 650, 10.1002/ana.21696 Kramer, 2006, Exercise, cognition, and the aging brain, J. Appl. Physiol., 101, 1237, 10.1152/japplphysiol.00500.2006 Landau, 2012, Association of lifetime cognitive engagement and low beta-amyloid deposition, Arch. Neurol., 69, 623, 10.1001/archneurol.2011.2748 Launer, 2002, Demonstrating the case that AD is a vascular disease: epidemiologic evidence, Ageing Res. Rev., 1, 61, 10.1016/S0047-6374(01)00364-5 Lazarov, 2005, Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice, Cell, 120, 701, 10.1016/j.cell.2005.01.015 Liang, 2010, Exercise and Alzheimer's disease biomarkers in cognitively normal older adults, Ann. Neurol., 68, 311, 10.1002/ana.22096 Logan, 1996, Distribution volume ratios without blood sampling from graphical analysis of PET data, J. Cereb. Blood Flow Metab., 16, 834, 10.1097/00004647-199609000-00008 Lovden, 2010, Experience-dependent plasticity of white-matter microstructure extends into old age, Neuropsychologia, 48, 3878, 10.1016/j.neuropsychologia.2010.08.026 Maillard, 2012, Coevolution of white matter hyperintensities and cognition in the elderly, Neurology, 79, 442, 10.1212/WNL.0b013e3182617136 Maillard, 2012, Effects of systolic blood pressure on white-matter integrity in young adults in the Framingham Heart Study: a cross-sectional study, Lancet Neurol., 11, 1039, 10.1016/S1474-4422(12)70241-7 Marchant, 2012, Cerebrovascular disease, beta-amyloid, and cognition in aging, Neurobiol. Aging, 33, 1006.e25, 10.1016/j.neurobiolaging.2011.10.001 Marshall, 2013, Apathy is associated with increased amyloid burden in mild cognitive impairment, J. Neuropsychiatry Clin. Neurosci., 25, 302, 10.1176/appi.neuropsych.12060156 Mintun, 2006, [11C]PIB in a nondemented population: potential antecedent marker of Alzheimer disease, Neurology, 67, 446, 10.1212/01.wnl.0000228230.26044.a4 Mori, 2014, Apathy correlates with prefrontal amyloid beta deposition in Alzheimer's disease, J. Neurol. Neurosurg. Psychiatry, 85, 449, 10.1136/jnnp-2013-306110 Mormino, 2012, Not quite PIB-positive, not quite PIB-negative: slight PIB elevations in elderly normal control subjects are biologically relevant, Neuroimage, 59, 1152, 10.1016/j.neuroimage.2011.07.098 Mormino, 2009, Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects, Brain, 132, 1310, 10.1093/brain/awn320 Newson, 2005, General lifestyle activities as a predictor of current cognition and cognitive change in older adults: a cross-sectional and longitudinal examination, J Gerontol. B Psychol. Sci. Soc. Sci., 60, P113, 10.1093/geronb/60.3.P113 Park, 2006, Cortical surface-based analysis of 18F-FDG PET: measured metabolic abnormalities in schizophrenia are affected by cortical structural abnormalities, Neuroimage, 31, 1434, 10.1016/j.neuroimage.2006.02.001 Perrotin, 2012, Subjective cognition and amyloid deposition imaging: a Pittsburgh Compound B positron emission tomography study in normal elderly individuals, Arch. Neurol., 69, 223, 10.1001/archneurol.2011.666 Pike, 2007, Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease, Brain, 130, 2837, 10.1093/brain/awm238 Preacher, 2004, SPSS and SAS procedures for estimating indirect effects in simple mediation models, Behav. Res. Methods Instrum. Comput., 36, 717, 10.3758/BF03206553 Preacher, 2008, Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models, Behav. Res. Methods, 40, 879, 10.3758/BRM.40.3.879 Raji, 2012, White matter lesions and brain gray matter volume in cognitively normal elders, Neurobiol. Aging, 33, 834.e7, 10.1016/j.neurobiolaging.2011.08.010 Rovio, 2010, The effect of midlife physical activity on structural brain changes in the elderly, Neurobiol. Aging, 31, 1927, 10.1016/j.neurobiolaging.2008.10.007 Rucker, 2011, Mediation analysis in social psychology: current practices and new recommendations, Soc. Personal Psychol. Compass, 5, 359, 10.1111/j.1751-9004.2011.00355.x Salthouse, 2006, Mental exercise and mental aging: evaluating the validity of the “use it or lose it” hypothesis, Perspect. Psychol. Sci., 1, 68, 10.1111/j.1745-6916.2006.00005.x Scarmeas, 2009, Physical activity, diet, and risk of Alzheimer disease, JAMA, 302, 627, 10.1001/jama.2009.1144 Schneider, 2010, Where vascular meets neurodegenerative disease, Stroke, 41, S144, 10.1161/STROKEAHA.110.598326 Shrout, 2002, Mediation in experimental and nonexperimental studies: new procedures and recommendations, Psychol. Methods, 7, 422, 10.1037/1082-989X.7.4.422 Siscovick, 1997, Exercise intensity and subclinical cardiovascular disease in the elderly. The Cardiovascular Health Study, Am. J. Epidemiol., 145, 977, 10.1093/oxfordjournals.aje.a009066 Smith, 2011, Correlations between MRI white matter lesion location and executive function and episodic memory, Neurology, 76, 1492, 10.1212/WNL.0b013e318217e7c8 Sole-Padulles, 2009, Brain structure and function related to cognitive reserve variables in normal aging, mild cognitive impairment and Alzheimer's disease, Neurobiol. Aging, 30, 1114, 10.1016/j.neurobiolaging.2007.10.008 Takeuchi, 2010, Training of working memory impacts structural connectivity, J. Neurosci., 30, 3297, 10.1523/JNEUROSCI.4611-09.2010 Taylor, 1978, A questionnaire for the assessment of leisure time physical activities, J. Chronic Dis., 31, 741, 10.1016/0021-9681(78)90058-9 Thies, 2013, 2013 Alzheimer's disease facts and figures, Alzheimers Dement., 9, 208, 10.1016/j.jalz.2013.02.003 Vemuri, 2012, Effect of lifestyle activities on Alzheimer disease biomarkers and cognition, Ann. Neurol., 72, 730, 10.1002/ana.23665 Voss, 2012, The influence of aerobic fitness on cerebral white matter integrity and cognitive function in older adults: results of a one-year exercise intervention, Hum. Brain Mapp., 34, 2972, 10.1002/hbm.22119 Wilson, 2003, Assessment of lifetime participation in cognitively stimulating activities, J. Clin. Exp. Neuropsychol., 25, 634, 10.1076/jcen.25.5.634.14572 Wilson, 2002, Cognitive activity and incident AD in a population-based sample of older persons, Neurology, 59, 1910, 10.1212/01.WNL.0000036905.59156.A1 Wilson, 2002, Participation in cognitively stimulating activities and risk of incident Alzheimer disease, JAMA, 287, 742, 10.1001/jama.287.6.742 Wirth, 2013, Alzheimer's disease neurodegenerative biomarkers are associated with decreased cognitive function but not beta-amyloid in cognitively normal older individuals, J. Neurosci., 33, 5553, 10.1523/JNEUROSCI.4409-12.2013 Wirth, 2013, The effect of amyloid beta on cognitive decline is modulated by neural integrity in cognitively normal elderly, Alzheimers Dement., 9, 687, 10.1016/j.jalz.2012.10.012 Wirth, 2013, Associations between alzheimer disease biomarkers, neurodegeneration, and cognition in cognitively normal older people, JAMA Neurol., 70, 1512 Yesavage, 1982, Development and validation of a geriatric depression screening scale: a preliminary report, J. Psychiatr. Res., 17, 37, 10.1016/0022-3956(82)90033-4