Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade
Tài liệu tham khảo
Burnstock, 1972, Purinergic nerves, Pharmacol. Rev., 24, 509
Ralevic, 1998, Receptors for purines and pyrimidines, Pharmacol. Rev., 50, 413
Burnstock, 2007, Physiology and pathophysiology of purinergic neurotransmission, Physiol. Rev., 87, 659, 10.1152/physrev.00043.2006
Vassort, 2001, Adenosine 5'-triphosphate: a P2-purinergic agonist in the myocardium, Physiol. Rev., 81, 767, 10.1152/physrev.2001.81.2.767
Roman, 1999, Emerging roles of purinergic signaling in gastrointestinal epithelial secretion and hepatobiliary function, Gastroenterology, 116, 964, 10.1016/S0016-5085(99)70081-8
Schwiebert, 2003, Extracellular ATP as a signaling molecule for epithelial cells, Biochim. Biophys. Acta, 1615, 7, 10.1016/S0005-2736(03)00210-4
Bucheimer, 2004, Purinergic regulation of epithelial transport, J. Physiol., 555, 311, 10.1113/jphysiol.2003.056697
Gonzalez-Alonso, 2002, Erythrocyte and the regulation of human skeletal muscle blood flow and oxygen delivery: role of circulating ATP, Circ. Res., 91, 1046, 10.1161/01.RES.0000044939.73286.E2
Sprague, 2007, Red not dead: signaling in and from erythrocytes, Trends Endocrinol. Metab., 18, 350, 10.1016/j.tem.2007.08.008
Bours, 2006, Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation, Pharmacol. Ther., 112, 358, 10.1016/j.pharmthera.2005.04.013
Salmi, 2005, Cell-surface enzymes in control of leukocyte trafficking, Nat. Rev. Immunol., 5, 760, 10.1038/nri1705
Marcus, 2003, Heterologous cell–cell interactions: thromboregulation, cerebroprotection and cardioprotection by CD39 (NTPDase-1), J. Thromb. Haemost., 1, 2497, 10.1111/j.1538-7836.2003.00479.x
Gachet, 2006, Regulation of platelet functions by P2 receptors, Annual Rev. Pharmacol. Toxicol., 46, 277, 10.1146/annurev.pharmtox.46.120604.141207
Burnstock, 2006, Pathophysiology and therapeutic potential of purinergic signaling, Pharmacol. Rev., 58, 58, 10.1124/pr.58.1.5
White, 2006, P2 receptors and cancer, Trends Pharmacol. Sci., 27, 211, 10.1016/j.tips.2006.02.004
Di Virgilio, 2002, P2 receptors: new potential players in atherosclerosis, Br. J. Pharmacol., 135, 831, 10.1038/sj.bjp.0704524
Hoebertz, 2003, Regulation of bone resorption and formation by purines and pyrimidines, Trends Pharmacol. Sci., 24, 290, 10.1016/S0165-6147(03)00123-8
North, 2002, Molecular physiology of P2X receptors, Physiol. Rev., 82, 1013, 10.1152/physrev.00015.2002
Abbracchio, 2006, International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy, Pharmacol. Rev., 58, 281, 10.1124/pr.58.3.3
Lazarowski, 2003, Mechanisms of release of nucleotides and integration of their action as P2X- and P2Y-receptor activating molecules, Mol. Pharmacol., 64, 785, 10.1124/mol.64.4.785
Zimmermann, 2000, Extracellular metabolism of ATP and other nucleotides, Naunyn Schmiedebergs Arch. Pharmacol., 362, 299, 10.1007/s002100000309
Robson, 2006, The E-NTPDase family of ectonucleotidases: structure function relationship and pathophysiological significance, Purinergic Signal., 2, 409, 10.1007/s11302-006-9003-5
Goding, 2003, Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/phosphodiesterase family, Biochim. Biophys. Acta, 1638, 1, 10.1016/S0925-4439(03)00058-9
Stefan, 2006, Modulation of purinergic signaling by NPP-type ectophosphodiesterases, Purinergic Signal., 2, 361, 10.1007/s11302-005-5303-4
Zimmermann, 1992, 5'-Nucleotidase: molecular structure and functional aspects, Biochem. J., 285, 345, 10.1042/bj2850345
Hunsucker, 2005, The 5'-nucleotidases as regulators of nucleotide and drug metabolism, Pharmacol. Ther., 107, 1, 10.1016/j.pharmthera.2005.01.003
Colgan, 2006, Physiological roles for ecto-5'-nucleotidase (CD73), Purinergic Signal., 2, 351, 10.1007/s11302-005-5302-5
Millan, 2006
Lazarowski, 1997, Identification of an ecto-nucleoside diphosphokinase and its contribution to interconversion of P2 receptor agonists, J. Biol. Chem., 272, 20402, 10.1074/jbc.272.33.20402
Yegutkin, 2002, The evidence for two opposite, ATP-generating and ATP-consuming, extracellular pathways on endothelial and lymphoid cells, Biochem. J., 367, 121, 10.1042/bj20020439
Shryock, 1997, Adenosine and adenosine receptors in the cardiovascular system: biochemistry, physiology, and pharmacology, Am. J. Cardiol., 79, 2, 10.1016/S0002-9149(97)00256-7
Spychala, 2000, Tumor-promoting functions of adenosine, Pharmacol. Ther., 87, 161, 10.1016/S0163-7258(00)00053-X
Jacobson, 2006, Adenosine receptors as therapeutic targets, Nat. Rev. Drug Discov., 5, 247, 10.1038/nrd1983
King, 2006, Nucleoside transporters: from scavengers to novel therapeutic targets, Trends Pharmacol. Sci., 27, 416, 10.1016/j.tips.2006.06.004
Loffler, 2007, Physiological roles of vascular nucleoside transporters, arteriosclerosis, Thromb. Vasc. Biol., 27, 1004, 10.1161/ATVBAHA.106.126714
Blackburn, 2005, Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammation, Adv. Immunol., 86, 1, 10.1016/S0065-2776(04)86001-2
Zimmermann, 1996, Biochemistry, localization and functional roles of ecto-nucleotidases in the nervous system, Prog. Neurobiol., 49, 589, 10.1016/0301-0082(96)00026-3
Sorensen, 2001, Visualization of ATP release in pancreatic acini in response to cholinergic stimulus. Use of fluorescent probes and confocal microscopy, J. Biol. Chem., 276, 32925, 10.1074/jbc.M103313200
Homolya, 2000, Cell to cell communication in response to mechanical stress via bilateral release of ATP and UTP in polarized epithelia, J. Cell Biol., 150, 1349, 10.1083/jcb.150.6.1349
Lazarowski, 2000, Constitutive release of ATP and evidence for major contribution of ecto-nucleotide pyrophosphatase and nucleoside diphosphokinase to extracellular nucleotide concentrations, J. Biol. Chem., 275, 31061, 10.1074/jbc.M003255200
Okada, 2006, Physiological regulation of ATP release at the apical surface of human airway epithelia, J. Biol. Chem., 281, 22992, 10.1074/jbc.M603019200
Bodin, 2001, Evidence that release of adenosine triphosphate from endothelial cells during increased shear stress is vesicular, J. Cardiovasc. Pharmacol., 38, 900, 10.1097/00005344-200112000-00012
Yegutkin, 2000, Effect of shear stress on the release of soluble ecto-enzymes ATPase and 5'-nucleotidase along with endogenous ATP from vascular endothelial cells, Br. J. Pharmacol., 129, 921, 10.1038/sj.bjp.0703136
Buxton, 2001, Evidence supporting the nucleotide axis hypothesis: ATP release and metabolism by coronary endothelium, Am. J. Physiol. Heart Circ. Physiol., 281, H1657, 10.1152/ajpheart.2001.281.4.H1657
Gerasimovskaya, 2002, Extracellular ATP is an autocrine/paracrine regulator of hypoxia-induced adventitial fibroblast growth. Signaling through extracellular signal-regulated kinase-1/2 and the Egr-1 transcription factor, J. Biol. Chem., 277, 44638, 10.1074/jbc.M203012200
Fabre, 2006, Cell surface adenylate kinase activity regulates the F(1)-ATPase/P2Y(13)-mediated HDL endocytosis pathway on human hepatocytes, Cell. Mol. Life Sci., 63, 2829, 10.1007/s00018-006-6325-y
Burrell, 2005, Human keratinocytes release ATP and utilize three mechanisms for nucleotide interconversion at the cell surface, J. Biol. Chem., 280, 29667, 10.1074/jbc.M505381200
Eltzschig, 2006, ATP release from activated neutrophils occurs via connexin 43 and modulates adenosine-dependent endothelial cell function, Circ. Res., 99, 1100, 10.1161/01.RES.0000250174.31269.70
Wong, 2006, Connexin37 protects against atherosclerosis by regulating monocyte adhesion, Nat. Med., 12, 950, 10.1038/nm1441
Madara, 1993, 5'-adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers.[see comment], J. Clin. Invest., 91, 2320, 10.1172/JCI116462
Strohmeier, 1997, Surface expression, polarization, and functional significance of CD73 in human intestinal epithelia, J. Clin. Invest., 99, 2588, 10.1172/JCI119447
Lennon, 1998, Neutrophil-derived 5'-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A2B receptor activation, J. Exp. Med., 188, 1433, 10.1084/jem.188.8.1433
Chen, 2006, ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors, Science, 314, 1792, 10.1126/science.1132559
Dale, 2000, Direct measurement of adenosine release during hypoxia in the CA1 region of the rat hippocampal slice, J. Physiol. 526 Pt, 1, 143, 10.1111/j.1469-7793.2000.00143.x
Martin, 2007, Adenosine released by asrocytes contributes to hypoxia-induced modulation of synaptic transmission, Glia, 55, 36, 10.1002/glia.20431
Bekar, 2008, Adenosine is crucial for deep brain stimulation-mediated attenuation of tremor, Nat. Medicine, 14, 75, 10.1038/nm1693
Lazarowski, 2004, Nucleotide release provides a mechanism for airway surface liquid homeostasis, J. Biol. Chem., 279, 36855, 10.1074/jbc.M405367200
Kreda, 2007, Coordinated release of nucleotides and mucin from human airway epithelial Calu-3 cells, J. Physiol., 584, 245, 10.1113/jphysiol.2007.139840
Koszalka, 2004, Targeted disruption of cd73/ecto-5'-nucleotidase alters thromboregulation and augments vascular inflammatory response.[see comment], Circ. Res., 95, 814, 10.1161/01.RES.0000144796.82787.6f
Zernecke, 2006, CD73/ecto-5'-nucleotidase protects against vascular inflammation and neointima formation, Circulation, 113, 2120, 10.1161/CIRCULATIONAHA.105.595249
Eckle, 2007, Cardioprotection by ecto-5'-nucleotidase (CD73) and A2B adenosine receptors, Circulation, 115, 1581, 10.1161/CIRCULATIONAHA.106.669697
Lazarowski, 1997, Direct demonstration of mechanically induced release of cellular UTP and its implication for uridine nucleotide receptor activation, J. Biol. Chem., 272, 24348, 10.1074/jbc.272.39.24348
Lazarowski, 2001, UTP as an extracellular signaling molecule, News in Physiological Sciences, 16, 1
Koizumi, 2007, UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis.[see comment], Nature, 446, 1091, 10.1038/nature05704
Wihlborg, 2006, Positive inotropic effects by uridine triphosphate (UTP) and uridine diphosphate (UDP) via P2Y2 and P2Y6 receptors on cardiomyocytes and release of UTP in man during myocardial infarction, Circ. Res., 98, 970, 10.1161/01.RES.0000217402.73402.cd
Lazarowski, 2003, Release of cellular UDP-glucose as a potential extracellular signaling molecule, Mol. Pharmacol., 63, 1190, 10.1124/mol.63.5.1190
Abbracchio, 2003, Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family, Trends Pharmacol. Sci., 24, 52, 10.1016/S0165-6147(02)00038-X
Schluter, 1996, Vascular actions of diadenosine phosphates, J. Auton. Pharm., 16, 357, 10.1111/j.1474-8673.1996.tb00053.x
Miras-Portugal, 2003, Ca2+ signalling in brain synaptosomes activated by dinucleotides, J. Mem. Biol., 194, 1, 10.1007/s00232-003-2024-x
Delicado, 2006, Dinucleoside polyphosphates and their interaction with other nucleotide signaling pathways, Pflugers Arch.— Europ. J. Physiol., 452, 563, 10.1007/s00424-006-0066-5
Flores, 1999, The effects of diadenosine polyphosphates on the cardiovascular system, Cardiovasc. Res., 42, 15, 10.1016/S0008-6363(99)00004-8
Schluter, 1998, Adenosine(5') oligophospho-(5') guanosines and guanosine(5') oligophospho-(5') guanosines in human platelets, J. Clin. Invest., 101, 682, 10.1172/JCI119882
Jankowski, 2005, Uridine adenosine tetraphosphate: a novel endothelium-derived vasoconstrictive factor, Nat. Med., 11, 223, 10.1038/nm1188
Stefan, 2005, NPP-type ectophosphodiesterases: unity in diversity, Trends Biochem. Sci., 30, 542, 10.1016/j.tibs.2005.08.005
Donaldson, 2002, Secreted and cell-associated adenylate kinase and nucleoside diphosphokinase contribute to extracellular nucleotide metabolism on human airway surfaces, Am. J. Respir. Cell. Mol. Biol., 26, 209, 10.1165/ajrcmb.26.2.4650
Yegutkin, 2001, Extracellular ATP formation on vascular endothelial cells is mediated by ecto-nucleotide kinase activities via phosphotransfer reactions, Faseb J., 15, 251, 10.1096/fj.00-0268com
Yegutkin, 2003, Soluble purine-converting enzymes circulate in human blood and regulate extracellular ATP level via counteracting pyrophosphatase and phosphotransfer reactions, Faseb J., 17, 1328, 10.1096/fj.02-1136fje
Yan, 1999, Nucleoside monophosphate kinases: structure, mechanism, and substrate specificity, Adv. Enzymol. Relat. Areas Mol. Biol., 73, 103
Yegutkin, 2000, Inhibitory effects of some purinergic agents on ecto-ATPase activity and pattern of stepwise ATP hydrolysis in rat liver plasma membranes, Biochim. Biophys. Acta, 1466, 234, 10.1016/S0005-2736(00)00165-6
Schneider, 1999, Continuous detection of extracellular ATP on living cells by using atomic force microscopy, Proc. Natl. Acad. Sci. U. S. A., 96, 12180, 10.1073/pnas.96.21.12180
Corriden, 2007, A novel method using fluorescence microscopy for real-time assessment of ATP release from individual cells, Am. J. Physiol. Cell. Physiol., 293, C1420, 10.1152/ajpcell.00271.2007
Mitchell, 1998, A release mechanism for stored ATP in ocular ciliary epithelial cells, Proc. Natl. Acad. Sci. U. S. A., 95, 7174, 10.1073/pnas.95.12.7174
Yegutkin, 2006, The detection of micromolar pericellular ATP pool on lymphocyte surface by using lymphoid ecto-adenylate kinase as intrinsic ATP sensor, Mol. Biol. Cell, 17, 3378, 10.1091/mbc.e05-10-0993
Hazama, 1998, Cell surface measurements of ATP release from single pancreatic beta cells using a novel biosensor technique, Pflugers Arch., 437, 31, 10.1007/s004240050742
Hayashi, 2004, Detecting ATP release by a biosensor method, Sci. STKE 2004, pl14
Llaudet, 2005, Microelectrode biosensor for real-time measurement of ATP in biological tissue, Anal. Chem., 77, 3267, 10.1021/ac048106q
Masse, 2007, Purine-mediated signalling triggers eye development, Nature, 449, 1058, 10.1038/nature06189
Henttinen, 2003, Adherent leukocytes prevent adenosine formation and impair endothelial barrier function by ecto-5'-nucleotidase/CD73-dependent mechanism, J. Biol. Chem., 278, 24888, 10.1074/jbc.M300779200
Nakamura, 2006, Cell-surface-localized ATP detection with immobilized firefly luciferase, Anal. Biochem., 352, 61, 10.1016/j.ab.2006.02.019
Beigi, 1999, Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase, Am. J. Physiol., 276, C267, 10.1152/ajpcell.1999.276.1.C267
Joseph, 2003, Colocalization of ATP release sites and ecto-ATPase activity at the extracellular surface of human astrocytes, J. Biol. Chem., 278, 23331, 10.1074/jbc.M302680200
Pellegatti, 2005, A Novel recombinant plasma membrane-targeted luciferase reveals a new pathway for ATP secretion, Mol. Biol. Cell, 16, 3659, 10.1091/mbc.e05-03-0222
Plesner, 1995, Ecto-ATPases: identities and functions, Int. Rev. Cytol., 158, 141, 10.1016/S0074-7696(08)62487-0
Zimmermann, 1996, Extracellular purine metabolism, Drug Dev. Res., 39, 337, 10.1002/(SICI)1098-2299(199611/12)39:3/4<337::AID-DDR15>3.0.CO;2-Z
Pearson, 1980, Metabolism of adenine nucleotides by ectoenzymes of vascular endothelial and smooth-muscle cells in culture, Biochem. J., 190, 421, 10.1042/bj1900421
Meghji, 1995, Kinetics of extracellular ATP hydrolysis by microvascular endothelial cells from rat heart, Biochem. J., 308, 725, 10.1042/bj3080725
Sevigny, 1997, Purification of the blood vessel ATP diphosphohydrolase, identification and localisation by immunological techniques, Biochim. Biophys. Acta, 1334, 73, 10.1016/S0304-4165(96)00079-7
Zimmermann, 2000, Proposed nomenclature for two novel nucleotide hydrolyzing enzyme families expressed on the cell surface, 1
Zimmermann, 2001, Ectonucleotidases: some recent developments and a note of nomenclature, Drug Dev. Res., 52, 44, 10.1002/ddr.1097
Maliszewski, 1994, The CD39 lymphoid cell activation antigen. Molecular cloning and structural characterization, J. Immunol., 153, 3574, 10.4049/jimmunol.153.8.3574
Handa, 1996, Purification and cloning of a soluble ATP-diphosphohydrolase (apyrase) from potato tubers (Solanum tuberosum), Biochem. Biophys. Res. Comm., 218, 916, 10.1006/bbrc.1996.0162
Kaczmarek, 1996, Identification and characterization of CD39/vascular ATP diphosphohydrolase, J. Biol. Chem., 271, 33116, 10.1074/jbc.271.51.33116
Wang, 1996, CD39 is an ecto-(Ca2+,Mg2+)-apyrase, J. Biol. Chem., 271, 9898, 10.1074/jbc.271.17.9898
Enjyoji, 1999, Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation, Nat. Med., 5, 1010, 10.1038/12447
Robson, 2005, Ectonucleotidases of CD39 family modulate vascular inflammation and thrombosis in transplantation, Semin. Thromb. Hemost., 31, 217, 10.1055/s-2005-869527
Sorensen, 2003, Rat pancreas secretes particulate ecto-nucleotidase CD39, J. Physiol., 551, 881, 10.1113/jphysiol.2003.049411
Mizumoto, 2002, CD39 is the dominant Langerhans cell-associated ecto-NTPDase: modulatory roles in inflammation and immune responsiveness, Nat. Med., 8, 358, 10.1038/nm0402-358
Deaglio, 2007, Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression, J. Exp. Med., 204, 1257, 10.1084/jem.20062512
Zimmermann, 2007, Ecto-nucleotidases, molecular properties and functional impact, Anales Real Academia Nacional Farmacia, 73, 537
Sevigny, 2002, Differential catalytic properties and vascular topography of murine nucleoside triphosphate diphosphohydrolase 1 (NTPDase1) and NTPDase2 have implications for thromboregulation, Blood, 99, 2801, 10.1182/blood.V99.8.2801
Langer, 2007, The ectonucleotidases alkaline phosphatase and nucleoside triphosphate diphosphohydrolase 2 are associated with subsets of progenitor cell populations in the mouse embryonic, postnatal and adult neurogenic zones, Neuroscience, 150, 863, 10.1016/j.neuroscience.2007.07.064
Belcher, 2006, Immunolocalization of ecto-nucleoside triphosphate diphosphohydrolase 3 in rat brain: implications for modulation of multiple homeostatic systems including feeding and sleep–wake behaviors, Neuroscience, 137, 1331, 10.1016/j.neuroscience.2005.08.086
Bigonnesse, 2004, Cloning and characterization of mouse nucleoside triphosphate diphosphohydrolase-8, Biochemistry, 43, 5511, 10.1021/bi0362222
Fausther, 2007, Cloning, purification, and identification of the liver canalicular ecto-ATPase as NTPDase8, Am. J. Physiol. — Gastrointest. Liver Physiol., 292, G785, 10.1152/ajpgi.00293.2006
Stout, 1996, Control of cell membrane ecto-ATPase by oligomerization state: intermolecular cross-linking modulates ATPase activity, Biochemistry, 35, 8289, 10.1021/bi960563g
Smith, 1999, Site-directed mutagenesis of a human brain ecto-apyrase: evidence that the E-type ATPases are related to the actin/heat shock 70/sugar kinase superfamily, Biochemistry, 38, 321, 10.1021/bi9820457
Kukulski, 2005, Comparative hydrolysis of P2 receptor agonists by NTPDases 1, 2, 3 and 8, Purinergic Signal., 1, 193, 10.1007/s11302-005-6217-x
Marcus, 1997, The endothelial cell ecto-ADPase responsible for inhibition of platelet function is CD39, J. Clin. Invest., 99, 1351, 10.1172/JCI119294
Yegutkin, 2006, ATP-consuming and ATP-generating enzymes secreted by pancreas, J. Biol. Chem., 281, 29441, 10.1074/jbc.M602480200
Wu, 2006, RanBPM associates with CD39 and modulates ecto-nucleotidase activity, Biochem. J., 396, 23, 10.1042/BJ20051568
Dombrowski, 1998, Ecto-ATPase: an activation marker necessary for effector cell function, Immunol. Rev., 161, 111, 10.1111/j.1600-065X.1998.tb01575.x
Heptinstall, 2005, Adenine nucleotide metabolism in human blood—important roles for leukocytes and erythrocytes, J. Thromb. Haemost., 3, 2331, 10.1111/j.1538-7836.2005.01489.x
Borsellino, 2007, Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression, Blood, 110, 1225, 10.1182/blood-2006-12-064527
Pinsky, 2002, Elucidation of the thromboregulatory role of CD39/ectoapyrase in the ischemic brain, J. Clin. Invest., 109, 1031, 10.1172/JCI0210649
Dwyer, 2004, Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation, J. Clin. Invest., 113, 1440, 10.1172/JCI19560
Jackson, 2007, Disordered purinergic signaling inhibits pathological angiogenesis in Cd39/Entpd1-null mice, Am. J. Pathol., 171, 1395, 10.2353/ajpath.2007.070190
Eckle, 2007, Identification of ectonucleotidases CD39 and CD73 in innate protection during acute lung injury, J. Immunol., 178, 8127, 10.4049/jimmunol.178.12.8127
Grenz, 2007, Contribution of E-NTPDase1 (CD39) to renal protection from ischemia–reperfusion injury, Faseb J., 21, 2863, 10.1096/fj.06-7947com
Kohler, 2007, CD39/ectonucleoside triphosphate diphosphohydrolase 1 provides myocardial protection during cardiac ischemia/reperfusion injury, Circulation, 116, 1784, 10.1161/CIRCULATIONAHA.107.690180
Vollmayer, 2003, Hydrolysis of diadenosine polyphosphates by nucleotide pyrophosphatases/phosphodiesterases, Eur. J. Biochem., 270, 2971, 10.1046/j.1432-1033.2003.03674.x
Yegutkin, 2007, Intravascular ADP and soluble nucleotidases contribute to acute prothrombotic state during vigorous exercise in humans, J. Physiol., 579, 553, 10.1113/jphysiol.2006.119453
van Meeteren, 2006, Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development, Mol. Cell. Biol., 26, 5015, 10.1128/MCB.02419-05
Terkeltaub, 2001, Inorganic pyrophosphate generation and disposition in pathophysiology, Am. J. Physiol. Cell. Physiol., 281, C1, 10.1152/ajpcell.2001.281.1.C1
Okawa, 1998, Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine, Nat. Genet., 19, 271, 10.1038/956
Rutsch, 2001, PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification, Am. J. Pathol., 158, 543, 10.1016/S0002-9440(10)63996-X
Hessle, 2002, Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization, Proc. Natl. Acad. Sci. U.S.A., 99, 9445, 10.1073/pnas.142063399
Martinez-Martinez, 2000, The ecto-5'-nucleotidase subunits in dimers are not linked by disulfide bridges but by non-covalent bonds, Biochim. Biophys. Acta, 1478, 300, 10.1016/S0167-4838(00)00035-2
Strater, 2006, Ecto-5'-nucleotidase: structure function relationships, Purinergic Signal., 2, 343, 10.1007/s11302-006-9000-8
Thompson, 2004, Crucial role for ecto-5'-nucleotidase (CD73) in vascular leakage during hypoxia, J. Exp. Med., 200, 1395, 10.1084/jem.20040915
Moriwaki, 1999, Enzymes involved in purine metabolism—a review of histochemical localization and functional implications, Histol. Histopathol., 14, 1321
Resta, 1998, Ecto-enzyme and signaling functions of lymphocyte CD73, Immunol. Rev., 161, 95, 10.1111/j.1600-065X.1998.tb01574.x
Yamashita, 1998, CD73 expression and fyn-dependent signaling on murine lymphocytes, Eur. J. Immunol., 28, 2981, 10.1002/(SICI)1521-4141(199810)28:10<2981::AID-IMMU2981>3.0.CO;2-D
Spychala, 1999, Tissue-specific regulation of the ecto-5'-nucleotidase promoter. Role of the camp response element site in mediating repression by the upstream regulatory region, J. Biol. Chem., 274, 22705, 10.1074/jbc.274.32.22705
Kobie, 2006, T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine, J. Immunol., 177, 6780, 10.4049/jimmunol.177.10.6780
Airas, 1997, Differential regulation and function of CD73, a glycosyl-phosphatidylinositol-linked 70-kD adhesion molecule, on lymphocytes and endothelial cells, J. Cell Biol., 136, 421, 10.1083/jcb.136.2.421
Niemela, 2004, IFN-alpha induced adenosine production on the endothelium: a mechanism mediated by CD73 (ecto-5'-nucleotidase) up-regulation, J. Immunol., 172, 1646, 10.4049/jimmunol.172.3.1646
Spychala, 1997, Adenosine metabolism during phorbol myristate acetate-mediated induction of HL-60 cell differentiation: changes in expression pattern of adenosine kinase, adenosine deaminase, and 5'-nucleotidase, J. Immunol., 158, 4947, 10.4049/jimmunol.158.10.4947
Ledoux, 2002, Lovastatin enhances ecto-5'-nucleotidase activity and cell surface expression in endothelial cells: implication of rho-family GTPases, Circ. Res., 90, 420, 10.1161/hh0402.105668
Narravula, 2000, Regulation of endothelial CD73 by adenosine: paracrine pathway for enhanced endothelial barrier function, J. Immunol., 165, 5262, 10.4049/jimmunol.165.9.5262
Synnestvedt, 2002, Ecto-5'-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia, J. Clin. Invest., 110, 993, 10.1172/JCI0215337
Morabito, 1998, Methotrexate and sulfasalazine promote adenosine release by a mechanism that requires ecto-5'-nucleotidase-mediated conversion of adenine nucleotides, J. Clin. Invest., 101, 295, 10.1172/JCI1554
Cronstein, 2005, Low-dose methotrexate: a mainstay in the treatment of rheumatoid arthritis, Pharmacol. Rev., 57, 163, 10.1124/pr.57.2.3
Huang, 2006, Ecto-5'-nucleotidase (cd73)-dependent and -independent generation of adenosine participates in the mediation of tubuloglomerular feedback in vivo, Am. J. Physiol. — Renal Physiol., 291, F282, 10.1152/ajprenal.00113.2005
Castrop, 2004, Impairment of tubuloglomerular feedback regulation of GFR in ecto-5'-nucleotidase/CD73-deficient mice.[see comment], J. Clin. Invest., 114, 634, 10.1172/JCI21851
Volmer, 2006, Ecto-5'-nucleotidase (CD73)-mediated adenosine production is tissue protective in a model of bleomycin-induced lung injury, J. Immunol., 176, 4449, 10.4049/jimmunol.176.7.4449
Millan, 2006, Alkaline phosphatases. Structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes, Purinergic Signal., 2, 335, 10.1007/s11302-005-5435-6
Say, 1991, Alkaline phosphatase from rat osseous plates: purification and biochemical characterization of a soluble form, Biochim. Biophys. Acta, 1074, 256, 10.1016/0304-4165(91)90161-9
Johnson, 2000, Osteoblast tissue-nonspecific alkaline phosphatase antagonizes and regulates PC-1, Am. J. Physiol. — Regul. Integr. Comp. Physiol., 279, R1365, 10.1152/ajpregu.2000.279.4.R1365
Waymire, 1995, Mice lacking tissue non-specific alkaline phosphatase die from seizures due to defective metabolism of vitamin B-6, Nat. Genet., 11, 45, 10.1038/ng0995-45
Narisawa, 1997, Inactivation of two mouse alkaline phosphatase genes and establishment of a model of infantile hypophosphatasia, Dev. Dyn., 208, 432, 10.1002/(SICI)1097-0177(199703)208:3<432::AID-AJA13>3.0.CO;2-1
Picher, 2003, Ecto 5'-nucleotidase and nonspecific alkaline phosphatase. Two AMP-hydrolyzing ectoenzymes with distinct roles in human airways, J. Biol. Chem., 278, 13468, 10.1074/jbc.M300569200
Franco, 1998, Enzymatic and extraenzymatic role of ecto-adenosine deaminase in lymphocytes, Immunol. Rev., 161, 27, 10.1111/j.1600-065X.1998.tb01569.x
Pacheco, 2005, CD26, adenosine deaminase, and adenosine receptors mediate costimulatory signals in the immunological synapse, Proc. Natl. Acad. Sci. U.S.A., 102, 9583, 10.1073/pnas.0501050102
Desrosiers, 2007, Adenosine deamination sustains dendritic cell activation in inflammation, J. Immunol., 179, 1884, 10.4049/jimmunol.179.3.1884
Zavialov, 2005, Human ADA2 belongs to a new family of growth factors with adenosine deaminase activity, Biochem. J., 391, 51, 10.1042/BJ20050683
Martin, 1995, Expression of ecto-adenosine deaminase and CD26 in human T cells triggered by the TCR–CD3 complex. Possible role of adenosine deaminase as costimulatory molecule, J. Immunol., 155, 4630, 10.4049/jimmunol.155.10.4630
Gorrell, 2001, CD26: a multifunctional integral membrane and secreted protein of activated lymphocytes, Scand. J. Immunol., 54, 249, 10.1046/j.1365-3083.2001.00984.x
Herrera, 2001, Adenosine A2B receptors behave as an alternative anchoring protein for cell surface adenosine deaminase in lymphocytes and cultured cells, Mol. Pharmacol., 59, 127, 10.1124/mol.59.1.127
Van Linden, 2007, Role of pulmonary adenosine during hypoxia: extracellular generation, signaling and metabolism by surface adenosine deaminase/CD26, Expert. Opin. Biol. Ther., 7, 1437, 10.1517/14712598.7.9.1437
Markert, 1994, Molecular basis of adenosine deaminase deficiency, Immunodeficiency, 5, 141
Migchielsen, 1995, Adenosine-deaminase-deficient mice die perinatally and exhibit liver-cell degeneration, atelectasis and small intestinal cell death, Nat. Genet., 10, 279, 10.1038/ng0795-279
Wakamiya, 1995, Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice, Proc. Natl. Acad. Sci. U.S.A., 92, 3673, 10.1073/pnas.92.9.3673
Blackburn, 1998, Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency, J. Biol. Chem., 273, 5093, 10.1074/jbc.273.9.5093
Toro, 2006, Intracellular delivery of purine nucleoside phosphorylase (PNP) fused to protein transduction domain corrects PNP deficiency in vitro, Cell. Immunol., 240, 107, 10.1016/j.cellimm.2006.07.003
Markert, 1991, Purine nucleoside phosphorylase deficiency, Immunodefic. Rev., 3, 45
Cohen, 2000, Immunodeficiency caused by purine nucleoside phosphorylase deficiency, Vol. 20, 143
Arpaia, 2000, Mitochondrial basis for immune deficiency. Evidence from purine nucleoside phosphorylase-deficient mice, J. Exp. Med., 191, 2197, 10.1084/jem.191.12.2197
Toro, 2006, TAT-mediated intracellular delivery of purine nucleoside phosphorylase corrects its deficiency in mice, J. Clin. Invest., 116, 2717, 10.1172/JCI25052
Dzeja, 2003, Phosphotransfer networks and cellular energetics, J. Exp. Biol., 206, 2039, 10.1242/jeb.00426
Dzeja, 2007, Integration of adenylate kinase, glycolytic and glycogenolytic circuits in cellular energetics, vol. 8, 265
Collavin, 1999, wt p53 dependent expression of a membrane-associated isoform of adenylate kinase, Oncogene, 18, 5879, 10.1038/sj.onc.1202970
Janssen, 2004, Two structurally distinct and spatially compartmentalized adenylate kinases are expressed from the AK1 gene in mouse brain, Mol. Cell. Biochem., 256–257, 59, 10.1023/B:MCBI.0000009859.15267.db
Ruan, 2002, Cellular characterization of adenylate kinase and its isoform: two-photon excitation fluorescence imaging and fluorescence correlation spectroscopy, Biophys. J., 83, 3177, 10.1016/S0006-3495(02)75320-4
Janssen, 2000, Adenylate kinase 1 gene deletion disrupts muscle energetic economy despite metabolic rearrangement, EMBO J., 19, 6371, 10.1093/emboj/19.23.6371
Dzeja, 2007, Defective metabolic signaling in adenylate kinase AK1 gene knockout hearts compromises post-ischemic coronary reflow, J. Biol. Chem., 282, 31366, 10.1074/jbc.M705268200
Carrasco, 2001, Adenylate kinase phosphotransfer communicates cellular energetic signals to ATP-sensitive potassium channels, Proc. Natl. Acad. Sci. U. S. A., 98, 7623, 10.1073/pnas.121038198
Randak, 2003, An intrinsic adenylate kinase activity regulates gating of the ABC transporter CFTR, Cell, 115, 837, 10.1016/S0092-8674(03)00983-8
Randak, 2005, Adenylate kinase activity in ABC transporters, J. Biol. Chem., 280, 34385, 10.1074/jbc.R500009200
Bhaskara, 2007, Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes.[see comment], Mol. Cell, 25, 647, 10.1016/j.molcel.2007.01.028
Dixon, 2003, ADP stimulation of inositol phosphates in hepatocytes: role of conversion to ATP and stimulation of P2Y2 receptors, Br. J. Pharmacol., 138, 272, 10.1038/sj.bjp.0705016
Picher, 2003, Human airway ecto-adenylate kinase. A mechanism to propagate atp signaling on airway surfaces, J. Biol. Chem., 278, 11256, 10.1074/jbc.M208071200
Sperlagh, 2007, Extracellular interconversion of nucleotides reveals an ecto-adenylate kinase activity in the rat hippocampus, Neurochem. Res., 32, 1978, 10.1007/s11064-007-9458-y
Quillen, 2006, Ectoadenylate kinase and plasma membrane ATP synthase activities of human vascular endothelial cells, J. Biol. Chem., 281, 20728, 10.1074/jbc.M513042200
Parks, 1973, Nucleoside diphosphokinases, vol. 8, 307
Otero, 2000, NM23/nucleoside diphosphate kinase and signal transduction, J. Bioenerg. Biomembranes, 32, 269, 10.1023/A:1005589029959
Lacombe, 2000, The human Nm23/nucleoside diphosphate kinases, J. Bioenerg. Biomembranes, 32, 247, 10.1023/A:1005584929050
Okabe-Kado, 2003, Physiological and pathological relevance of extracellular NM23/NDP kinases, J. Bioenerg. Biomembranes, 35, 89, 10.1023/A:1023402125186
Arnaud-Dabernat, 2003, Knockout mice as model systems for studying nm23/NDP kinase gene functions. Application to the nm23-M1 gene, J. Bioenerg. Biomembranes, 35, 19, 10.1023/A:1023561821551
Muimo, 2006, Nucleoside diphosphate kinase A as a controller of AMP-kinase in airway epithelia, J. Bioenerg. Biomembranes, 38, 181, 10.1007/s10863-006-9033-2
Seong, 2007, NM23-H1 tumor suppressor physically interacts with serine–threonine kinase receptor-associated protein, a transforming growth factor-beta (TGF-beta) receptor-interacting protein, and negatively regulates TGF-beta signaling, J. Biol. Chem., 282, 12075, 10.1074/jbc.M609832200
Fournier, 2002, Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha) ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement, J. Biol. Chem., 277, 20895, 10.1074/jbc.M200200200
Palacios, 2002, ARF6-GTP recruits Nm23-H1 to facilitate dynamin-mediated endocytosis during adherens junctions disassembly, Nat. Cell Biol., 4, 929, 10.1038/ncb881
Garzia, 2006, H-prune-nm23-H1 protein complex and correlation to pathways in cancer metastasis, J. Bioenerg. Biomembranes, 38, 205, 10.1007/s10863-006-9036-z
Ronquist, 1968, Formation of extracellular adenosine triphosphate by human erythrocytes, Acta Physiol. Scand., 74, 594, 10.1111/j.1748-1716.1968.tb04270.x
Еgren, 1974, Nucleoside diphosphate kinase at the cell surface of neoplastic human cells in culture, J. Cell. Physiol., 83, 91, 10.1002/jcp.1040830113
Boyer, 1997, The ATP synthase—a splendid molecular machine, Annu. Rev. Biochem., 66, 717, 10.1146/annurev.biochem.66.1.717
Yoshida, 2001, ATP synthase—a marvellous rotary engine of the cell, Nat. Rev. Mol. Cell Biol., 2, 669, 10.1038/35089509
Ko, 2003, Mitochondrial ATP synthasome. Cristae-enriched membranes and a multiwell detergent screening assay yield dispersed single complexes containing the ATP synthase and carriers for Pi and ADP/ATP, J. Biol. Chem., 278, 12305, 10.1074/jbc.C200703200
Das, 1994, A novel ligand in lymphocyte-mediated cytotoxicity: expression of the b subunit of H+ transporting ATP synthase on the surface of tumor cell lines, J. Exp. Med., 180, 273, 10.1084/jem.180.1.273
Moser, 2001, Endothelial cell surface F1-F0 ATP synthase is active in ATP synthesis and is inhibited by angiostatin, Proc. Natl. Acad. Sci. U. S. A., 98, 6656, 10.1073/pnas.131067798
Yamamoto, 2007, Involvement of cell-surface ATP synthase in flow-induced ATP release by vascular endothelial cells, Am. J. Physiol. Heart Circ. Physiol., 293, H1646, 10.1152/ajpheart.01385.2006
Kim, 2004, Extracellular ATP is generated by ATP synthase complex in adipocyte lipid rafts, Exp. Mol. Med., 36, 476, 10.1038/emm.2004.60
Chi, 2006, Angiostatin is directly cytotoxic to tumor cells at low extracellular pH: a mechanism dependent on cell surface-associated ATP synthase, Cancer Res., 66, 875, 10.1158/0008-5472.CAN-05-2806
Scotet, 2005, Tumor recognition following Vgamma9Vdelta2 T cell receptor interactions with a surface F1-ATPase-related structure and apolipoprotein A-I, Immunity, 22, 71, 10.1016/j.immuni.2004.11.012
Gordon, 1989, The hydrolysis of extracellular adenine nucleotides by arterial smooth muscle cells. Regulation of adenosine production at the cell surface, J. Biol. Chem., 264, 18986, 10.1016/S0021-9258(19)47255-4
Eltzschig, 2003, Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors, J. Exp. Med., 198, 783, 10.1084/jem.20030891
Pike, 2004, Lipid rafts: heterogeneity on the high seas, Biochem. J., 378, 281, 10.1042/bj20031672
Kittel, 1999, CD39 as a caveolar-associated ectonucleotidase, Biochem. Biophys. Res. Comm., 262, 596, 10.1006/bbrc.1999.1254
Koziak, 2000, Palmitoylation targets CD39/endothelial ATP diphosphohydrolase to caveolae, J. Biol. Chem., 275, 2057, 10.1074/jbc.275.3.2057
Papanikolaou, 2005, Cholesterol-dependent lipid assemblies regulate the activity of the ecto-nucleotidase CD39, J. Biol. Chem., 280, 26406, 10.1074/jbc.M413927200
Lasley, 2000, Activated cardiac adenosine A(1) receptors translocate out of caveolae, J. Biol. Chem., 275, 4417, 10.1074/jbc.275.6.4417
Kaiser, 2002, Functional compartmentation of endothelial P2Y receptor signaling, Circ. Res., 91, 292, 10.1161/01.RES.0000030711.21521.AC
Vial, 2005, Disruption of lipid rafts inhibits P2X1 receptor-mediated currents and arterial vasoconstriction, J. Biol. Chem., 280, 30705, 10.1074/jbc.M504256200
Vacca, 2004, P2X3 receptor localizes into lipid rafts in neuronal cells, J. Neurosci. Res., 76, 653, 10.1002/jnr.20069
Jorgensen, 1956, Breakdown of adenine and hypoxanthine nucleotides and nucleosides in human plasma, Acta Pharm. Toxicol., 12, 294, 10.1111/j.1600-0773.1956.tb01389.x
Ireland, 1966, Detection and determination of adenosine diphosphate and related substances in plasma, Biochem. J., 99, 283, 10.1042/bj0990283
Coade, 1989, Metabolism of adenine nucleotides in human blood, Circ. Res., 65, 531, 10.1161/01.RES.65.3.531
Birk, 2002, Role of extracellular ATP metabolism in regulation of platelet reactivity, J. Lab. Clin. Med., 140, 166, 10.1067/mlc.2002.126719
Haslam, 1967, The adenylate kinase of human plasma, erythrocytes and platelets in relation to the degradation of adenosine diphosphate in plasma, Biochem. J., 103, 773, 10.1042/bj1030773
Todorov, 1997, Neuronal release of soluble nucleotidases and their role in neurotransmitter inactivation, Nature, 387, 76, 10.1038/387076a0
Beaudoin, 1986, Microvesicular secretion, a mode of cell secretion associated with the presence of an ATP-diphosphohydrolase, FEBS Lett., 203, 1, 10.1016/0014-5793(86)81423-5
Smith, 2002, Cloning, expression, and characterization of a soluble calcium-activated nucleotidase, a human enzyme belonging to a new family of extracellular nucleotidases, Archiv. Biochem. Biophys., 406, 105, 10.1016/S0003-9861(02)00420-4
Yang, 2004, Site-directed mutagenesis of human soluble calcium-activated nucleotidase 1 (hSCAN-1): identification of residues essential for enzyme activity and the Ca(2+)-induced conformational change, Biochemistry, 43, 9185, 10.1021/bi049565o
Valenzuela, 1998, Purification, cloning, and expression of an apyrase from the bed bug Cimex lectularius. A new type of nucleotide-binding enzyme, J. Biol. Chem., 273, 30583, 10.1074/jbc.273.46.30583
Failer, 2002, Cloning, expression, and functional characterization of a Ca(2+)-dependent endoplasmic reticulum nucleoside diphosphatase, J. Biol. Chem., 277, 36978, 10.1074/jbc.M201656200
Dai, 2004, Structure and protein design of a human platelet function inhibitor.[erratum appears in Cell. 2004 Apr 30;117(3):413], Cell, 116, 649, 10.1016/S0092-8674(04)00172-2