Toxicology of nanoparticles

Borzelleca, 2000, Paracelsus: herald of modern toxicology, Toxicol. Sci., 53, 2, 10.1093/toxsci/53.1.2 Rozman, 2001, Paracelsus, Haber and Arndt, Toxicology, 160, 191, 10.1016/S0300-483X(00)00447-9 Donaldson, 2004, Nanotoxicology, Occup. Environ. Med., 61, 727, 10.1136/oem.2004.013243 Jefferson, 2000, The surface activity of ultrafine particles, Philosophical Transactions of the Royal Society of London, Series A: Mathematical, Phys. Eng. Sci., 358, 2683, 10.1098/rsta.2000.0677 Stone, 2006, Nanotoxicology: signs of stress, Nat. Nanotechnol., 1, 23, 10.1038/nnano.2006.69 Kane, 2008, Nanotoxicology: the asbestos analogy revisited, Nat. Nanotechnol., 3, 378, 10.1038/nnano.2008.182 Dockery, 1993, An association between air pollution and mortality in six U.S. cities, N. Engl. J. Med., 329, 1753, 10.1056/NEJM199312093292401 Donaldson, 2005, Combustion-derived nanoparticles: a review of their toxicology following inhalation exposure, Part. Fibre Toxicol., 2, 10, 10.1186/1743-8977-2-10 Hansen, 2008, Categorization framework to aid exposure assessment of nanomaterials in consumer products, Ecotoxicology, 17, 438, 10.1007/s10646-008-0210-4 Kunzli, 2000, Public-health impact of outdoor and traffic-related air pollution: a European assessment, Lancet, 356, 795, 10.1016/S0140-6736(00)02653-2 Kunzli, 2005, Ambient air pollution and atherosclerosis in Los Angeles, Environ. Health Perspect., 113, 201, 10.1289/ehp.7523 Oberdorster, 2002, Ultrafine particles in the urban air: to the respiratory tract—and beyond?, Environ. Health Perspect., 110, A440, 10.1289/ehp.110-a440 Wichmann, 2000, Epidemiological evidence of the effects of ultrafine particle exposure, Philosophical Transactions of the Royal Society of London, Series A: Mathematical, Phys. Eng. Sci., 358, 2751, 10.1098/rsta.2000.0682 Burleson, 2004, On the characterization of environmental nanoparticles, J. Environ. Sci. Health A Tox. Hazard. Subst. Environ. Eng., 39, 2707, 10.1081/ESE-200027029 Sayes, 2009, Characterization of nanomaterials for toxicity assessment, Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol., 1, 660, 10.1002/wnan.58 Park, 2010, Commercially manufactured engineered nanomaterials for environmental and health studies: important insights provided by independent characterization, Environ. Toxicol. Chem., 29, 715, 10.1002/etc.72 Tomalia, 2009, In quest of a systematic framework for unifying and defining nanoscience, J. Nanopart. Res., 11, 1251, 10.1007/s11051-009-9632-z Brown, 2010, Nanoparticle characterization for cancer nanotechnology and other biological applications, Methods Mol. Biol., 624, 39, 10.1007/978-1-60761-609-2_4 Donaldson, 2000, Ultrafine particles: mechanisms of lung injury, Philosophical Transactions of the Royal Society of London, Series A: Mathematical, Phys. Eng. Sci., 358, 2741, 10.1098/rsta.2000.0681 Oberdürster, 2000, Toxicology of ultrafine particles: in vivo studies, Philosophical Transactions of the Royal Society of London, Series A: Mathematical, Phys. Eng. Sci., 358, 2719, 10.1098/rsta.2000.0680 Song, 2009, Exposure to nanoparticles is related to pleural effusion, pulmonary fibrosis and granuloma, Eur. Respir. J., 34, 559, 10.1183/09031936.00178308 Oberdorster, 2010, Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology, J. Intern. Med., 267, 89, 10.1111/j.1365-2796.2009.02187.x Wittmaack, 2007, In search of the most relevant parameter for quantifying lung inflammatory response to nanoparticle exposure: particle number, surface area, or what?, Environ. Health Perspect., 115, 187, 10.1289/ehp.9254 Oberdörster, 2010, Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology, J. Intern. Med., 267, 89, 10.1111/j.1365-2796.2009.02187.x Elsaesser, 2010, Quantification of nanoparticle uptake by cells using microscopical and analytical techniques, Nanomedicine (Lond.), 5, 1447, 10.2217/nnm.10.118 Nel, 2009, Understanding biophysicochemical interactions at the nano-bio interface, Nat. Mater., 8, 543, 10.1038/nmat2442 Navarro, 2008, Environmental behavior and ecotoxicity of engineered nanoparticles to algae, plants, and fungi, Ecotoxicology, 17, 372, 10.1007/s10646-008-0214-0 Lynch, 2007, The nanoparticle-protein complex as a biological entity; a complex fluids and surface science challenge for the 21st century, Adv. Colloid Interface Sci., 134–135, 167, 10.1016/j.cis.2007.04.021 Cedervall, 2007, Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles, Proc. Natl. Acad. Sci. U.S.A., 104, 2050, 10.1073/pnas.0608582104 Lynch, 2009, Protein–nanoparticle interactions: what does the cell see?, Nat Nano, 4, 546, 10.1038/nnano.2009.248 Handy, 2008, The ecotoxicology and chemistry of manufactured nanoparticles, Ecotoxicology, 17, 287, 10.1007/s10646-008-0199-8 Quik, 2010, Effect of natural organic matter on cerium dioxide nanoparticles settling in model fresh water, Chemosphere, 81, 711, 10.1016/j.chemosphere.2010.07.062 Kiser, 2010, Biosorption of nanoparticles to heterotrophic wastewater biomass, Water Res., 44, 4105, 10.1016/j.watres.2010.05.036 Nowack, 2009, The behavior and effects of nanoparticles in the environment, Environ. Pollut., 157, 1063, 10.1016/j.envpol.2008.12.019 Wiesner, 2008, Nanomaterials as possible contaminants: the fullerene example, Water Sci. Technol., 57, 305, 10.2166/wst.2008.800 Garnett, 2006, Nanomedicines and nanotoxicology: some physiological principles, Occup Med (Lond), 56, 307, 10.1093/occmed/kql052 Yacobi, 2010, Mechanisms of alveolar epithelial translocation of a defined population of nanoparticles, Am. J. Respir. Cell Mol. Biol., 42, 604, 10.1165/rcmb.2009-0138OC Greulich, 2011, Uptake and intracellular distribution of silver nanoparticles in human mesenchymal stem cells, Acta Biomater., 7, 347, 10.1016/j.actbio.2010.08.003 Nel, 2006, Toxic potential of materials at the nanolevel, Science, 311, 622, 10.1126/science.1114397 Xia, 2008, Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties, ACS Nano, 2, 2121, 10.1021/nn800511k Auffan, 2008, Relation between the redox state of iron-based nanoparticles and their cytotoxicity toward Escherichia coli, Environ. Sci. Technol., 42, 6730, 10.1021/es800086f Foley, 2002, Cellular localisation of a water-soluble fullerene derivative, Biochem. Biophys. Res. Commun., 294, 116, 10.1016/S0006-291X(02)00445-X Kamat, 2000, Reactive oxygen species mediated membrane damage induced by fullerene derivatives and its possible biological implications, Toxicology, 155, 55, 10.1016/S0300-483X(00)00277-8 Cottingham, 2002, Amyloid fibril formation by a synthetic peptide from a region of human acetylcholinesterase that is homologous to the Alzheimer's amyloid-beta peptide, Biochemistry, 41, 13539, 10.1021/bi0260334 Gou, 2010, Mechanistic toxicity assessment of nanomaterials by whole-cell-array stress genes expression analysis, Environ. Sci. Technol., 44, 5964, 10.1021/es100679f Elaine, 1996, Inflammation, free radicals, and antioxidants, Nutrition, 12, 274, 10.1016/S0899-9007(96)00000-8 Li, 2008, The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles, Free Radic. Biol. Med., 44, 1689, 10.1016/j.freeradbiomed.2008.01.028 Li, 2003, Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage, Environ. Health Perspect., 111, 455, 10.1289/ehp.6000 Uchino, 2002, Quantitative determination of OH radical generation and its cytotoxicity induced by TiO2-UVA treatment, Toxicol. Vitr., 16, 629, 10.1016/S0887-2333(02)00041-3 Walczyk, 2010, What the Cell “Sees” in Bionanoscience, J. Am. Chem. Soc., 132, 5761, 10.1021/ja910675v Leroueil, 2008, Wide varieties of cationic nanoparticles induce defects in supported lipid bilayers, Nano Lett., 8, 420, 10.1021/nl0722929 Hussain, 2005, In vitro toxicity of nanoparticles in BRL 3A rat liver cells, Toxicol. In Vitro, 19, 975, 10.1016/j.tiv.2005.06.034 Øvrevik, 2004, p38 and Src-ERK1/2 pathways regulate crystalline silica-induced chemokine release in pulmonary epithelial cells, Toxicol. Sci., 81, 480, 10.1093/toxsci/kfh214 Hauck, 2008, Assessing the effect of surface chemistry on gold nanorod uptake, toxicity, and gene expression in mammalian cells, Small, 4, 153, 10.1002/smll.200700217 Billsten, 1997, Adsorption to silica nanoparticles of human carbonic anhydrase II and truncated forms induce a molten-globule-like structure, FEBS Lett., 402, 67, 10.1016/S0014-5793(96)01431-7 Chen, 2005, Formation of nucleoplasmic protein aggregates impairs nuclear function in response to SiO2 nanoparticles, Exp. Cell Res., 305, 51, 10.1016/j.yexcr.2004.12.021 Poland, 2008, Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study, Nat. Nanotechnol., 3, 423, 10.1038/nnano.2008.111 Unfried, 2007, Cellular responses to nanoparticles: target structures and mechanisms, Nanotoxicology, 1, 52, 10.1080/00222930701314932 Vasir, 2008, Quantification of the force of nanoparticle–cell membrane interactions and its influence on intracellular trafficking of nanoparticles, Biomaterials, 29, 4244, 10.1016/j.biomaterials.2008.07.020 Peetla, 2008, Biophysical characterization of nanoparticle–endothelial model cell membrane interactions, Mol. Pharm., 5, 418, 10.1021/mp700140a Ginzburg, 2007, Modeling the thermodynamics of the interaction of nanoparticles with cell membranes, Nano Lett., 7, 3716, 10.1021/nl072053l Rodea-Palomares, 2011, Physicochemical characterization and ecotoxicological assessment of CeO2 nanoparticles using two aquatic microorganisms, Toxicol. Sci., 119, 135, 10.1093/toxsci/kfq311 Zhu, 2006, The interaction and toxicity of multi-walled carbon nanotubes with Stylonychia mytilus, J. Nanosci. Nanotechnol., 6, 1357, 10.1166/jnn.2006.194 Xia, 2006, Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm, Nano Lett., 6, 1794, 10.1021/nl061025k Jia, 2005, Cytotoxicity of carbon nanomaterials: single-wall nanotube, multi-wall nanotube, and fullerene, Environ. Sci. Technol., 39, 1378, 10.1021/es048729l Al-Rawi, 2011, Uptake and intracellular localization of submicron and nano-sized SiO(2) particles in HeLa cells, Arch. Toxicol., 85, 813, 10.1007/s00204-010-0642-5 Parfenov, 2006, Aqueous diffusion pathways as a part of the ventricular cell ultrastructure, Biophys. J., 90, 1107, 10.1529/biophysj.105.071787 Godbey, 1999, Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery, Proc. Natl. Acad. Sci. U.S.A., 96, 5177, 10.1073/pnas.96.9.5177 Pante, 2002, Nuclear pore complex is able to transport macromolecules with diameters of 39nm, Mol. Biol. Cell, 13, 425, 10.1091/mbc.01-06-0308 Williams, 2009, Probing cell-type-specific intracellular nanoscale barriers using size-tuned quantum dots, Small, 5, 2581, 10.1002/smll.200900744 Nabiev, 2007, Nonfunctionalized nanocrystals can exploit a cell's active transport machinery delivering them to specific nuclear and cytoplasmic compartments, Nano Lett., 7, 3452, 10.1021/nl0719832 Hoshino, 2004, Quantum dots targeted to the assigned organelle in living cells, Microbiol. Immunol., 48, 985, 10.1111/j.1348-0421.2004.tb03621.x Dobson, 2003, Protein folding and misfolding, Nature, 426, 884, 10.1038/nature02261 Marano, 2011, Nanoparticles: molecular targets and cell signalling, Arch. Toxicol., 85, 733, 10.1007/s00204-010-0546-4 Dawson, 2009, Nanotoxicology: nanoparticles reconstruct lipids, Nat. Nanotechnol., 4, 84, 10.1038/nnano.2008.426 De, 2008, Synthetic “chaperones”: nanoparticle-mediated refolding of thermally denatured proteins, Chem. Commun., 3504, 10.1039/b805242e Shang, 2007, Unfolding of ribonuclease A on silica nanoparticle surfaces, Nano Lett., 7, 1991, 10.1021/nl070777r Takahashi, 2011, Amphiphilic polysaccharide nanoballs: a new building block for nanogel biomedical engineering and artificial chaperones, ACS Nano, 5, 337, 10.1021/nn101447m Ishii, 2003, Chaperonin-mediated stabilization and ATP-triggered release of semiconductor nanoparticles, Nature, 423, 628, 10.1038/nature01663 Akiyoshi, 1999, Molecular chaperone-like activity of hydrogel nanoparticles of hydrophobized pullulan: thermal stabilization with refolding of carbonic anhydrase B, Bioconjug. Chem., 10, 321, 10.1021/bc9801272 Wu, 2008, TiO2 nanoparticles promote beta-amyloid fibrillation in vitro, Biochem. Biophys. Res. Commun., 373, 315, 10.1016/j.bbrc.2008.06.035 Wagner, 2010, Nanoparticle-induced folding and fibril formation of coiled-coil-based model peptides, Small, 6, 1321, 10.1002/smll.200902067 Aili, 2008, Folding induced assembly of polypeptide decorated gold nanoparticles, J. Am. Chem. Soc., 130, 5780, 10.1021/ja711330f Bucciantini, 2002, Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases, Nature, 416, 507, 10.1038/416507a Barnes, 2008, Reproducible comet assay of amorphous silica nanoparticles detects no genotoxicity, Nano Lett., 8, 3069, 10.1021/nl801661w Karlsson, 2010, The comet assay in nanotoxicology research, Anal. Bioanal. Chem., 398, 651, 10.1007/s00216-010-3977-0 Xie, 2009, Nuclear targeted nanoprobe for single living cell detection by surface-enhanced Raman scattering, Bioconjug. Chem., 20, 768, 10.1021/bc800469g Mehrabi, 2007, Intercalating gold nanoparticles as universal labels for DNA detection, Small, 3, 1491, 10.1002/smll.200700230 Bhabra, 2009, Nanoparticles can cause DNA damage across a cellular barrier, Nat Nano, 4, 876, 10.1038/nnano.2009.313 Myllynen, 2009, Nanotoxicology: damaging DNA from a distance, Nat. Nanotechnol., 4, 795, 10.1038/nnano.2009.365 Rivera Gil, 2010, Correlating physico-chemical with toxicological properties of nanoparticles: the present and the future, ACS Nano, 4, 5527, 10.1021/nn1025687 Seaton, 2010, Nanoparticles, human health hazard and regulation, J. R. Soc. Interface, 7, S119, 10.1098/rsif.2009.0252.focus Mueller, 2008, Exposure modeling of engineered nanoparticles in the environment, Environ. Sci. Technol., 42, 4447, 10.1021/es7029637 Park, 2008, Hazard and risk assessment of a nanoparticulate cerium oxide-based diesel fuel additive—a case study, Inhal. Toxicol., 20, 547, 10.1080/08958370801915309 Napierska, 2010, The nanosilica hazard: another variable entity, Part. Fibre Toxicol., 7, 39, 10.1186/1743-8977-7-39 Osmond, 2010, Zinc oxide nanoparticles in modern sunscreens: an analysis of potential exposure and hazard, Nanotoxicology, 4, 15, 10.3109/17435390903502028 Ahamed, 2010, Silver nanoparticle applications and human health, Clin. Chim. Acta, 411, 1841, 10.1016/j.cca.2010.08.016 Aitken, 2006, Manufacture and use of nanomaterials: current status in the UK and global trends, Occup Med (Lond), 56, 300, 10.1093/occmed/kql051 Sperling, 2008, Biological applications of gold nanoparticles, Chem. Soc. Rev., 37, 1896, 10.1039/b712170a Stern, 2008, Nanotechnology safety concerns revisited, Toxicol. Sci., 101, 4, 10.1093/toxsci/kfm169 Elder, 2009, Human Health Risks of Engineered Nanomaterials, 3 Donaldson, 2002, The pulmonary toxicology of ultrafine particles, J. Aerosol Med., 15, 213, 10.1089/089426802320282338 Bennett, 2002, Rapid translocation of nanoparticles from the lung to the bloodstream?, Am. J. Respir. Crit. Care Med., 165, 1671, 10.1164/rccm145 Geiser, 2010, Update on macrophage clearance of inhaled micro- and nanoparticles, J. Aerosol Med. Pulm. Drug Deliv., 23, 207, 10.1089/jamp.2009.0797 Choi, 2010, Rapid translocation of nanoparticles from the lung airspaces to the body, Nat. Biotechnol., 28, 1300, 10.1038/nbt.1696 Liu, 2009, Potential health impact on mice after nasal instillation of nano-sized copper particles and their translocation in mice, J. Nanosci. Nanotechnol., 9, 6335, 10.1166/jnn.2009.1320 Elder, 2006, Translocation of inhaled ultrafine manganese oxide particles to the central nervous system, Environ. Health Perspect., 114, 1172, 10.1289/ehp.9030 Crosera, 2009, Nanoparticle dermal absorption and toxicity: a review of the literature, Int. Arch. Occup. Environ. Health, 82, 1043, 10.1007/s00420-009-0458-x Rouse, 2006, Effects of mechanical flexion on the penetration of fullerene amino acid-derivatized peptide nanoparticles through skin, Nano Lett., 7, 155, 10.1021/nl062464m Ryman-Rasmussen, 2006, Penetration of intact skin by quantum dots with diverse physicochemical properties, Toxicol. Sci., 91, 159, 10.1093/toxsci/kfj122 Ryman-Rasmussen, 2007, Surface coatings determine cytotoxicity and irritation potential of quantum dot nanoparticles in epidermal keratinocytes, J. Invest. Dermatol., 127, 143, 10.1038/sj.jid.5700508 Florence, 2005, Nanoparticle uptake by the oral route: fulfilling its potential?, Drug Discovery Today: Technologies, 2, 75, 10.1016/j.ddtec.2005.05.019 Jani, 1990, Nanoparticle uptake by the rat gastrointestinal mucosa: quantitation and particle size dependency, J. Pharm. Pharmacol., 42, 821, 10.1111/j.2042-7158.1990.tb07033.x Powell, 2010, Origin and fate of dietary nanoparticles and microparticles in the gastrointestinal tract, J. Autoimmun., 34, J226, 10.1016/j.jaut.2009.11.006 Hagens, 2007, What do we (need to) know about the kinetic properties of nanoparticles in the body?, Regul. Toxicol. Pharmacol., 49, 217, 10.1016/j.yrtph.2007.07.006 Yamashita, 2011, Silica and titanium dioxide nanoparticles cause pregnancy complications in mice, Nat Nano, 6, 321, 10.1038/nnano.2011.41 Hillyer, 2001, Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles, J. Pharm. Sci., 90, 1927, 10.1002/jps.1143 Nemmar, 2002, Passage of inhaled particles into the blood circulation in humans, Circulation, 105, 411, 10.1161/hc0402.104118 Ji, 2006, Biodistribution and tumor uptake of C60(OH) x in mice, J. Nanopart. Res., 8, 53, 10.1007/s11051-005-9001-5 Oberdorster, 2002, Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats, J. Toxicol. Environ. Health A, 65, 1531, 10.1080/00984100290071658 Borm, 2006, The potential risks of nanomaterials: a review carried out for ECETOC, Part. Fibre Toxicol., 3, 11, 10.1186/1743-8977-3-11 Nigavekar, 2004, 3H dendrimer nanoparticle organ/tumor distribution, Pharm. Res., 21, 476, 10.1023/B:PHAM.0000019302.26097.cc Xie, 2011, Tissue distribution and excretion of intravenously administered titanium dioxide nanoparticles, Toxicol. Lett., 10.1016/j.toxlet.2011.04.034 He, 2011, In vivo biodistribution and urinary excretion of mesoporous silica nanoparticles: effects of particle size and PEGylation, Small, 7, 271, 10.1002/smll.201001459 Longmire, 2008, Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats, Nanomedicine, 3, 703, 10.2217/17435889.3.5.703 Linse, 2007, Nucleation of protein fibrillation by nanoparticles, Proc. Natl. Acad. Sci. U.S.A., 104, 8691, 10.1073/pnas.0701250104 Oberdorster, 2009, Nanoparticles and the brain: cause for concern?, J. Nanosci. Nanotechnol., 9, 4996, 10.1166/jnn.2009.GR02 Oberdorster, 2002, Toxicokinetics and effects of fibrous and nonfibrous particles, Inhal. Toxicol., 14, 29, 10.1080/089583701753338622 Donaldson, 2010, Asbestos, carbon nanotubes and the pleural mesothelium: a review of the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma, Part. Fibre Toxicol., 7, 5, 10.1186/1743-8977-7-5 Myllynen, 2008, Kinetics of gold nanoparticles in the human placenta, Reprod. Toxicol., 26, 130, 10.1016/j.reprotox.2008.06.008 Tsuchiya, 1996, Novel harmful effects of [60]fullerene on mouse embryos in vitro and in vivo, FEBS Lett., 393, 139, 10.1016/0014-5793(96)00812-5