Polymorphism of interleukin-1 receptor antagonist gene and obesity

Bouchard, 1988, Heredity and body fat, Annu. Rev. Nutr., 8, 259, 10.1146/annurev.nu.08.070188.001355 Price, 1990, Common major gene inheritance of extreme overweight, Hum. Biol., 62, 747 Stunkard, 1990, The body-mass index of twins who have been reared apart, N. Engl. J. Med., 322, 1483, 10.1056/NEJM199005243222102 Bouchard, 1993, Genetics of obesity, Annu. Rev. Nutr., 13, 337, 10.1146/annurev.nu.13.070193.002005 Bouchard, 1996, Current status of the human obesity gene map, Obes. Res., 4, 81, 10.1002/j.1550-8528.1996.tb00516.x Hotamisligil, 1995, Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance, J. Clin. Invest., 95, 2409, 10.1172/JCI117936 Fernandez-Real, 1997, The TNF-alpha gene NcoI polymorphism influences the relationship among insulin resistance, percent body fat, and increased serum leptin concentrations, Diabetes, 46, 1468, 10.2337/diabetes.46.9.1468 Herrmann, 1998, Polymorphisms of the tumour necrosis factor-alpha gene, coronary heart disease and obesity, Eur. J. Clin. Invest., 28, 59, 10.1046/j.1365-2362.1998.00244.x Stylianou, 1998, Interleukin-1, Int. J. Biochem. Cell Biol., 30, 1075, 10.1016/S1357-2725(98)00081-8 Price, 1986, Regulation of lipoprotein lipase synthesis and 3T3-L1 adipocyte metabolism by recombinant interleukin 1, Biochim. Biophys. Acta, 889, 374, 10.1016/0167-4889(86)90201-6 Memon, 1998, Regulation of fatty acid transport protein and fatty acid translocase mRNA concentrations by endotoxin and cytokines, Am. J. Physiol., 274, E210 Sonti, 1996, Anorexia induced by cytokine interactions at pathophysiological concentrations, Am. J. Physiol., 270, R1394 Plata-Salaman, 1997, Differential responsiveness of obese (fa/fa) and lean (Fa/Fa) Zucker rats to cytokine-induced anorexia, Obes. Res., 5, 36, 10.1002/j.1550-8528.1997.tb00281.x Dinarello, 1994, The interleukin-1 family: 10 years of discovery, FASEB J., 8, 1314, 10.1096/fasebj.8.15.8001745 Meier, 2002, IL-1 receptor antagonist serum concentrations are increased in human obesity: a possible link to the resistance to leptin?, J. Clin. Endocrinol. Metab., 87, 1184, 10.1210/jc.87.3.1184 Tarlow, 1993, Polymorphism in human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeat, Hum. Genet., 91, 403, 10.1007/BF00217368 Santtila, 1998, Presence of the IL-1RA allele 2 (IL1RN*2) is associated with enhanced IL-1beta production in vitro, Scand. J. Immunol., 47, 195, 10.1046/j.1365-3083.1998.00300.x Hurme, 1998, IL-1 receptor antagonist (IL-1Ra) plasma concentrations are co-ordinately regulated by both IL-1Ra and IL-1beta genes, Eur. J. Immunol., 28, 2598, 10.1002/(SICI)1521-4141(199808)28:08<2598::AID-IMMU2598>3.0.CO;2-K Miller, 1988, A simple salting out procedure for extracting DNA from human nucleated cells, Nucleic Acids Res., 16, 1215, 10.1093/nar/16.3.1215 Danis, 1995, Cytokine production by normal human monocytes: inter-subject variation and relationship to an IL-1 receptor antagonist (IL-1Ra) gene polymorphism, Clin. Exp. Immunol., 99, 303, 10.1111/j.1365-2249.1995.tb05549.x Sciacca, 1999, Relevance of interleukin 1 receptor antagonist intron 2 polymorphism in Italian MS patients, Neurology, 52, 1896, 10.1212/WNL.52.9.1896 Nishimura, 2002, Contribution of the interleukin-1beta gene polymorphism in multiple system atrophy, Mov. Disord., 17, 808, 10.1002/mds.10124 Tseng, 2001, Single nucleotide polymorphisms in intron 2 of the human interleukin-1 receptor antagonist (IL-1Ra) gene: further definition of the IL-1 beta and IL-1Ra polymorphisms in North American Caucasians and Taiwanese Chinese, Tissue Antigens, 57, 318, 10.1034/j.1399-0039.2001.057004318.x Arner, 2000, Obesity—a genetic disease of adipose tissue?, Br. J. Nutr., 83, S9, 10.1017/S0007114500000891 Um, 2003, Polymorphism of angiotensin-converting enzyme gene and BMI in obese Korean women, Clin. Chim. Acta, 328, 173, 10.1016/S0009-8981(02)00428-X Um JY, Mun KS, An NH, Song YS, Lee KM, Kim HM. Gene polymorphisms in tumor necrosis factor locus and waist–hip ratio in obese Koreans. Clin Chim Acta [in press]. Nicklin, 2000, Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene, J. Exp. Med., 191, 303, 10.1084/jem.191.2.303 Horai, 2000, Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice, J. Exp. Med., 191, 313, 10.1084/jem.191.2.313 Hirsch, 1996, Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice, Proc. Natl. Acad. Sci. U. S. A., 93, 11008, 10.1073/pnas.93.20.11008 Arend, 1998, Interleukin-1 receptor antagonist: role in biology, Annu. Rev. Immunol., 16, 27, 10.1146/annurev.immunol.16.1.27 Luheshi, 1999, Leptin actions on food intake and body temperature are mediated by IL-1, Proc. Natl. Acad. Sci. U. S. A., 96, 7047, 10.1073/pnas.96.12.7047