Biomarkers of endothelial dysfunction in preeclampsia and neonatal morbidity: a case–control study

Folkman, 2007, Angiogenesis: an organizing principle for drug discovery, Nature, 6, 273 Carmeliet, 1995, Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF 164 and VEGF 188, Nat Med, 5, 495, 10.1038/8379 Moodley, 2007, Maternal deaths due to hypertensive disorders in pregnancy. Saving Mothers Report 2002–2004, Cardiovasc J Afr, 18, 358 2000, Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy, Am J Obstet Gynecol, 183, 1, 10.1067/mob.2000.107928 Merviel, 2004, Pathophysiology of preeclampsia: links with implantation disorders, Eur J Obstet Gynecol Reprod Biol, 115, 134, 10.1016/j.ejogrb.2003.12.030 Brosens, 1972, The role of the spiral arteries in the pathogenesis of preeclampsia, Obstet Gynecol Annu, 1, 177 Baumwell, 2007, Preeclampsia: clinical manifestations and molecular mechanisms, Nephron Clin Pract, 106, 72, 10.1159/000101801 Olsson, 2006, VEGF receptor signaling in control of vascular function, Nat Rev Mol Cell Biol, 7, 359, 10.1038/nrm1911 Ferrara, 2003, The biology of VEGF and its receptors, Nat Med, 9, 666, 10.1038/nm0603-669 Keck, 1989, Vascular permeability factor, an endothelial cell mitogen related to PDGF, Science, 246, 1309, 10.1126/science.2479987 Ribatti, 2008, The discovery of the placental growth factor and its role in angiogenesis: a historical review, Angiogenesis, 11, 215, 10.1007/s10456-008-9114-4 Kendal, 1993, Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor, Proc Acad Sci USA, 90, 10705, 10.1073/pnas.90.22.10705 Cebe-Suarez, 2006, The role of vascular endothelial growth factor in angiogenesis: complex partnerships, Cell Mol Life Sci, 63, 601, 10.1007/s00018-005-5426-3 Shibuya, 2005, Signal transduction by VEGF in regulation of angiogenesis and lymphangiogenesis, Exp Cell Res, 312, 549, 10.1016/j.yexcr.2005.11.012 Leanos-Miranda, 2013, Circulating angiogenic factors and urinary prolactin as predictors of adverse outcomes in women with preeclampsia, Hypertension, 61, 1118, 10.1161/HYPERTENSIONAHA.111.00754 Tjoa, 2007, Angiogenic factors and preeclampsia, Front Biosci, 12, 2395, 10.2741/2241 Moore Simas, 2007, Angiogenic factors for the prediction of preeclampsia in high risk women, Am J Obstet Gynecol, 197, 10.1016/j.ajog.2007.06.030 Wilkström, 2007, Placental growth factor and soluble FMS-like tyrosine kinase-1 in early-onset and late-onset preeclampsia, Obstet Gynecol, 109, 1368, 10.1097/01.AOG.0000264552.85436.a1 De Vivo, 2008, Endoglin, PLGF and sFLt-1 as markers for predicting pre-eclampsia, Acta Obstet Gynecol Scand, 87, 837, 10.1080/00016340802253759 Lyall, 1997, Suppression of serum vascular endothelial growth factor immunoreactivity in normal pregnancy and preeclampsia, Br J Obstet Gynecol, 104, 223, 10.1111/j.1471-0528.1997.tb11050.x Varughese, 2010, Circulating angiogenic factors in pregnancies complicated by preeclampsia, Natl Med J India, 23, 77 Maynard, 2003, Excess placental soluble Fms-like tyrosine kinase-1 (sFlt-1) may contribute to endothelial dysfunction, hypertension and proteinuria in preeclampsia, J Clin Invest, 111, 649, 10.1172/JCI17189 Maynard, 2005, Soluble fms-like tyrosine kinase-1 and endothelial dysfunction in the pathogenesis of preeclampsia, Pediatr Res, 57, 1R, 10.1203/01.PDR.0000159567.85157.B7 Alon, 1995, Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity, Nat Med, 1, 1024, 10.1038/nm1095-1024 Gerber, 1998, Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells, J Biol Chem, 273, 13313, 10.1074/jbc.273.21.13313 Benjamin, 1999, Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal, J Clin Invest, 103, 159, 10.1172/JCI5028 Yang, 1996, Effects of vascular endothelial growth factor on hemodynamics and cardiac performance, J Cardiovasc Pharmacol, 27, 838, 10.1097/00005344-199606000-00011 Auterio, 2003, Role of PLGF in the intra- and intermolecular cross talk between the VEGF receptors flt1 and flk1, Nat Med, 9, 936, 10.1038/nm884 Levine, 2004, Circulating angiogenic factors and the risk of preeclampsia, N Engl J Med, 12, 672, 10.1056/NEJMoa031884 Sibai, 1991, Hemodynamics of preeclampsia, Clin Perinatol, 18, 727, 10.1016/S0095-5108(18)30493-7 Bosio, 1999, Maternal hemodynamics in hypertensive disorders of pregnancy, Obstet Gynecol, 94, 978, 10.1016/S0029-7844(99)00430-5 Hibbard, 2004, Cardiovascular changes in preeclampsia, Semin Nephrol, 24, 580, 10.1016/j.semnephrol.2004.07.007 Masoura, 2012, Neonatal outcome of late preterm deliveries with preeclampsia, Minerva Gynecol, 64, 109 Villar, 2006, Preeclampsia, gestational hypertension and intrauterine growth restriction, related or independent conditions, Am J Obstet Gynecol, 194, 921, 10.1016/j.ajog.2005.10.813 Srinivas, 2009, Rethinking IUGR in preeclampsia: dependent or independent of maternal hypertension, J Perinatol, 29, 680, 10.1038/jp.2009.83