Hedgehog signaling plays a conserved role in inhibiting fat formation
Tài liệu tham khảo
Ashrafi, 2003, Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes, Nature, 421, 268, 10.1038/nature01279
Bak, 2003, The Hedgehog signaling pathway–implications for drug targets in cancer and neurodegenerative disorders, Pharmacogenomics, 4, 411, 10.1517/phgs.4.4.411.22751
Brand, 1994, Ectopic expression in Drosophila, Methods Cell Biol., 44, 635, 10.1016/S0091-679X(08)60936-X
Buhman, 2004, Inhibition of Hedgehog signaling protects adult mice from diet-induced weight gain, J. Nutr., 134, 2979, 10.1093/jn/134.11.2979
Cadigan, 1997, Wnt signaling: a common theme in animal development, Genes Dev., 11, 3286, 10.1101/gad.11.24.3286
Chen, 2002, Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened, Genes Dev., 16, 2743, 10.1101/gad.1025302
Chen, 1996, Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs, Genes Dev., 10, 2794, 10.1101/gad.10.21.2794
Cinti, 2000, Anatomy of the adipose organ, Eat. Weight Disord., 5, 132, 10.1007/BF03354443
Craven, 2004, Gata2 specifies serotonergic neurons downstream of sonic hedgehog, Development, 131, 1165, 10.1242/dev.01024
Duman-Scheel, 2002, Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E, Nature, 417, 299, 10.1038/417299a
Fajas, 2002, The retinoblastoma-histone deacetylase 3 complex inhibits PPARgamma and adipocyte differentiation, Dev. Cell, 3, 903, 10.1016/S1534-5807(02)00360-X
Gering, 2005, Hedgehog signaling is required for adult blood stem cell formation in zebrafish embryos, Dev. Cell, 8, 389, 10.1016/j.devcel.2005.01.010
Graff, 1997, Embryonic patterning: To BMP or not to BMP that is the question, Cell, 89, 171, 10.1016/S0092-8674(00)80196-8
Gratzner, 1982, Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication, Science, 218, 474, 10.1126/science.7123245
Hansen, 2004, Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation, Proc. Natl. Acad. Sci. USA, 101, 4112, 10.1073/pnas.0301964101
Hoshizaki, 1994, Embryonic fat-cell lineage in Drosophila melanogaster, Development, 120, 2489, 10.1242/dev.120.9.2489
Ingham, 2001, Hedgehog signaling in animal development: paradigms and principles, Genes Dev., 15, 3059, 10.1101/gad.938601
Ingram, 2002, Novel genes regulated by Sonic Hedgehog in pluripotent mesenchymal cells, Oncogene, 21, 8196, 10.1038/sj.onc.1205975
Karsenty, 1998, Transcriptional regulation of osteoblast differentiation during development, Front. Biosci., 3, d834, 10.2741/A326
Kenney, 2000, Sonic hedgehog promotes G(1) cyclin expression and sustained cell cycle progression in mammalian neuronal precursors, Mol. Cell. Biol., 20, 9055, 10.1128/MCB.20.23.9055-9067.2000
Li, 2004, Hedgehog can drive terminal differentiation of amniote slow skeletal muscle, BMC Dev. Biol., 4, 9, 10.1186/1471-213X-4-9
MacDougald, 1995, Transcriptional regulation of gene expression during adipocyte differentiation, Annu. Rev. Biochem., 64, 345, 10.1146/annurev.bi.64.070195.002021
Marigo, 1996, Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development, Dev. Biol., 180, 273, 10.1006/dbio.1996.0300
Martin, 2002, Increase in adipose and total body weight, but not in lean body mass, associated with subcutaneous administration of sonic hedgehog-Ig fusion protein to mice, Drug Dev. Res., 57, 107, 10.1002/ddr.10115
McKay, 2003, C. elegans. A Model for Exploring the Genetics of Fat Storage, Dev. Cell, 4, 131, 10.1016/S1534-5807(02)00411-2
McMahon, 2003, Developmental roles and clinical significance of hedgehog signaling, Curr. Top. Dev. Biol., 53, 1, 10.1016/S0070-2153(03)53002-2
Mikkola, 2002, The search for the hemangioblast, J. Hematother. Stem Cell Res., 11, 9, 10.1089/152581602753448504
Molkentin, 1996, Defining the regulatory networks for muscle development, Curr. Opin. Genet. Dev., 6, 445, 10.1016/S0959-437X(96)80066-9
Ramirez-Zacarias, 1992, Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O, Histochemistry, 97, 493, 10.1007/BF00316069
Rosen, 2000, Molecular regulation of adipogenesis, Annu. Rev. Cell Dev. Biol., 16, 145, 10.1146/annurev.cellbio.16.1.145
Rosenfeld, 1998, HLH106, a Drosophila sterol regulatory element-binding protein in a natural cholesterol auxotroph, J. Biol. Chem., 273, 16112, 10.1074/jbc.273.26.16112
Ross, 2000, Inhibition of adipogenesis by Wnt signaling, Science, 289, 950, 10.1126/science.289.5481.950
Sasaki, 1999, Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling, Development, 126, 3915, 10.1242/dev.126.17.3915
Shi, 2003, A glucocorticoid-induced leucine-zipper protein, GILZ, inhibits adipogenesis of mesenchymal cells, EMBO Rep., 4, 374, 10.1038/sj.embor.embor805
Smith, 1995, Gata-3 dominant negative mutant, J. Biol. Chem., 270, 1515, 10.1074/jbc.270.4.1515
Sottile, 2000, Bone morphogenetic protein-2 stimulates adipogenic differentiation of mesenchymal precursor cells in synergy with BRL 49653 (rosiglitazone), FEBS Lett., 475, 201, 10.1016/S0014-5793(00)01655-0
Spiegelman, 2001, Obesity and the regulation of energy balance, Cell, 104, 531, 10.1016/S0092-8674(01)00240-9
Spinella-Jaegle, 2001, Sonic hedgehog increases the commitment of pluripotent mesenchymal cells into the osteoblastic lineage and abolishes adipocytic differentiation, J. Cell Sci., 114, 2085, 10.1242/jcs.114.11.2085
Sul, 2000, Function of pref-1 as an inhibitor of adipocyte differentiation, Int. J. Obes. Relat. Metab. Disord., 24, S15, 10.1038/sj.ijo.0801494
Sweet, 1996, Mesenchymal dysplasia: a recessive mutation on chromosome 13 of the mouse, J. Hered., 87, 87, 10.1093/oxfordjournals.jhered.a022981
Taipale, 2000, Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine, Nature, 406, 1005, 10.1038/35023008
Tang, 2003, Mitotic clonal expansion: a synchronous process required for adipogenesis, Proc. Natl. Acad. Sci. USA, 100, 44, 10.1073/pnas.0137044100
Taylor, 1979, Multiple phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine, Cell, 17, 771, 10.1016/0092-8674(79)90317-9
Tong, 2000, Function of GATA transcription factors in preadipocyte-adipocyte transition, Science, 290, 134, 10.1126/science.290.5489.134
van der Horst, 2003, Hedgehog stimulates only osteoblastic differentiation of undifferentiated KS483 cells, Bone, 33, 899, 10.1016/j.bone.2003.07.004
Wang, 2000, Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus, Genes Dev., 14, 2893, 10.1101/gad.843900
Wang, 2004, Multiple Cos2/Ci interactions regulate Ci subcellular localization through microtubule dependent and independent mechanisms, Dev. Biol., 268, 493, 10.1016/j.ydbio.2004.01.008
Wang, 2002, Disruption of hedgehog signaling reveals a novel role in intestinal morphogenesis and intestinal-specific lipid metabolism in mice, Gastroenterology, 122, 469, 10.1053/gast.2002.31102
Wu, 2004, Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway, Chem. Biol., 11, 1229, 10.1016/j.chembiol.2004.06.010