Repression of the Heat Shock Response Is a Programmed Event at the Onset of Reproduction

Molecular Cell - Tập 59 - Trang 639-650 - 2015
Johnathan Labbadia1, Richard I. Morimoto1
1Department of Molecular Biosciences, Rice Institute for Biomedical Research, Northwestern University, Evanston, IL 60208, USA

Tài liệu tham khảo

Agger, 2007, UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development, Nature, 449, 731, 10.1038/nature06145 Akerfelt, 2010, Heat shock factors: integrators of cell stress, development and lifespan, Nat. Rev. Mol. Cell Biol., 11, 545, 10.1038/nrm2938 Arantes-Oliveira, 2002, Regulation of life-span by germ-line stem cells in Caenorhabditis elegans, Science, 295, 502, 10.1126/science.1065768 Ben-Zvi, 2009, Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging, Proc. Natl. Acad. Sci. USA, 106, 14914, 10.1073/pnas.0902882106 Brenner, 1974, The genetics of Caenorhabditis elegans, Genetics, 77, 71, 10.1093/genetics/77.1.71 David, 2010, Widespread protein aggregation as an inherent part of aging in C. elegans, PLoS Biol., 8, e1000450, 10.1371/journal.pbio.1000450 Dorschner, 2004, High-throughput localization of functional elements by quantitative chromatin profiling, Nat. Methods, 1, 219, 10.1038/nmeth721 Egelhofer, 2011, An assessment of histone-modification antibody quality, Nat. Struct. Mol. Biol., 18, 91, 10.1038/nsmb.1972 Haynes, 2013, Evaluating and responding to mitochondrial dysfunction: the mitochondrial unfolded-protein response and beyond, Trends Cell Biol., 23, 311, 10.1016/j.tcb.2013.02.002 Henis-Korenblit, 2010, Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity, Proc. Natl. Acad. Sci. USA, 107, 9730, 10.1073/pnas.1002575107 Hirsh, 1976, Development of the reproductive system of Caenorhabditis elegans, Dev. Biol., 49, 200, 10.1016/0012-1606(76)90267-0 Hoogewijs, 2008, Selection and validation of a set of reliable reference genes for quantitative sod gene expression analysis in C. elegans, BMC Mol. Biol., 9, 9, 10.1186/1471-2199-9-9 Hsu, 2003, Regulation of aging and age-related disease by DAF-16 and heat-shock factor, Science, 300, 1142, 10.1126/science.1083701 Huang, 2011, Neuronal expression of TATA box-binding protein containing expanded polyglutamine in knock-in mice reduces chaperone protein response by impairing the function of nuclear factor-Y transcription factor, Brain, 134, 1943, 10.1093/brain/awr146 Jin, 2011, Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway, Cell Metab., 14, 161, 10.1016/j.cmet.2011.07.001 Kamath, 2003, Systematic functional analysis of the Caenorhabditis elegans genome using RNAi, Nature, 421, 231, 10.1038/nature01278 Kirkwood, 1977, Evolution of ageing, Nature, 270, 301, 10.1038/270301a0 Labbadia, 2015, The biology of proteostasis in aging and disease, Annu. Rev. Biochem., 84, 435, 10.1146/annurev-biochem-060614-033955 Labbadia, 2011, Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease, J. Clin. Invest., 121, 3306, 10.1172/JCI57413 Lapierre, 2011, Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans, Curr. Biol., 21, 1507, 10.1016/j.cub.2011.07.042 Maures, 2011, The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner, Aging Cell, 10, 980, 10.1111/j.1474-9726.2011.00738.x Morimoto, 2008, Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging, Genes Dev., 22, 1427, 10.1101/gad.1657108 Morley, 2004, Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones, Mol. Biol. Cell, 15, 657, 10.1091/mbc.E03-07-0532 Morton, 2013, Caenorhabditis elegans HSF-1 is an essential nuclear protein that forms stress granule-like structures following heat shock, Aging Cell, 12, 112, 10.1111/acel.12024 Mukhopadhyay, 2008, Chromatin immunoprecipitation (ChIP) coupled to detection by quantitative real-time PCR to study transcription factor binding to DNA in Caenorhabditis elegans, Nat. Protoc., 3, 698, 10.1038/nprot.2008.38 Ntziachristos, 2014, Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia, Nature, 514, 513, 10.1038/nature13605 Olzscha, 2011, Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions, Cell, 144, 67, 10.1016/j.cell.2010.11.050 Prahlad, 2008, Regulation of the cellular heat shock response in Caenorhabditis elegans by thermosensory neurons, Science, 320, 811, 10.1126/science.1156093 Rea, 2005, A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans, Nat. Genet., 37, 894, 10.1038/ng1608 Reis-Rodrigues, 2012, Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan, Aging Cell, 11, 120, 10.1111/j.1474-9726.2011.00765.x Shemesh, 2013, Germline stem cell arrest inhibits the collapse of somatic proteostasis early in Caenorhabditis elegans adulthood, Aging Cell, 12, 814, 10.1111/acel.12110 Shore, 2012, Induction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathways, PLoS Genet., 8, e1002792, 10.1371/journal.pgen.1002792 Siebold, 2010, Polycomb Repressive Complex 2 and Trithorax modulate Drosophila longevity and stress resistance, Proc. Natl. Acad. Sci. USA, 107, 169, 10.1073/pnas.0907739107 Sykiotis, 2010, Stress-activated cap’n’collar transcription factors in aging and human disease, Sci. Signal., 3, re3, 10.1126/scisignal.3112re3 Tatum, 2015, Neuronal serotonin release triggers the heat shock response in C. elegans in the absence of temperature increase, Curr. Biol., 25, 163, 10.1016/j.cub.2014.11.040 Taylor, 2013, XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity, Cell, 153, 1435, 10.1016/j.cell.2013.05.042 Tullet, 2008, Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans, Cell, 132, 1025, 10.1016/j.cell.2008.01.030 van Oosten-Hawle, 2013, Regulation of organismal proteostasis by transcellular chaperone signaling, Cell, 153, 1366, 10.1016/j.cell.2013.05.015 Vandamme, 2012, The C. elegans H3K27 demethylase UTX-1 is essential for normal development, independent of its enzymatic activity, PLoS Genet., 8, e1002647, 10.1371/journal.pgen.1002647 Vilchez, 2012, RPN-6 determines C. elegans longevity under proteotoxic stress conditions, Nature, 489, 263, 10.1038/nature11315 Voigt, 2013, A double take on bivalent promoters, Genes Dev., 27, 1318, 10.1101/gad.219626.113 Walter, 2011, The unfolded protein response: from stress pathway to homeostatic regulation, Science, 334, 1081, 10.1126/science.1209038 Wang, 2008, Fat metabolism links germline stem cells and longevity in C. elegans, Science, 322, 957, 10.1126/science.1162011 Zuryn, 2014, Transdifferentiation. Sequential histone-modifying activities determine the robustness of transdifferentiation, Science, 345, 826, 10.1126/science.1255885