Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament

Altmuller, 2001, Genomewide scans of complex human diseases: true linkage is hard to find., Am J Hum Genet, 69, 936, 10.1086/324069 Averbook, 2002, A long-term analysis of 1018 patients with melanoma by classic Cox regression and tree-structured survival analysis at a major referral center: Implications on the future of cancer staging., Surgery, 132, 589, 10.1067/msy.2002.127546 Bhavnani, 2000, A nationwide, multicenter, case-control study comparing risk factors, treatment, and outcome for vancomycin-resistant and -susceptible enterococcal bacteremia., Diagn Microbiol Infect Dis, 36, 145, 10.1016/S0732-8893(99)00136-4 Buckner, 2001, A phase III study of radiation therapy plus carmustine with or without recombinant interferon-alpha in the treatment of patients with newly diagnosed high-grade glioma., Cancer, 92, 420, 10.1002/1097-0142(20010715)92:2<420::AID-CNCR1338>3.0.CO;2-3 Cardon, 2001, Association study designs for complex diseases., Nat Rev, 2, 91, 10.1038/35052543 Carlson, 2003, Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans., Nat Genet, 33, 518, 10.1038/ng1128 Cartegni, 2002, Listening to silence and understanding nonsense: exonic mutations that affect splicing., Nat Rev Genet, 3, 285, 10.1038/nrg775 Caterina, 1997, The capsaicin receptor: a heat-activated ion channel in the pain pathway., Nature, 389, 816, 10.1038/39807 Caterina, 2000, Impaired nociception and pain sensation in mice lacking the capsaicin receptor., Science, 288, 306, 10.1126/science.288.5464.306 Chesler, 2002, Influences of laboratory environment on behavior., Nat Neurosci, 5, 1101, 10.1038/nn1102-1101 Death, 2000, Classification and regression trees: a powerful yet simple technique for ecological data analysis., Ecology, 81, 3178, 10.1890/0012-9658(2000)081[3178:CARTAP]2.0.CO;2 Dennis, 2003, Epigenetics and disease: altered states., Nature, 421, 686, 10.1038/421686a Edwards, 1999, Ethnic differences in thermal pain responses., Psychosom Med, 61, 346, 10.1097/00006842-199905000-00014 Edwards, 2000, Sex-specific effects of pain-related anxiety on adjustment to chronic pain., Clin J Pain, 16, 46, 10.1097/00002508-200003000-00008 Edwards, 2001, Race, ethnicity and pain., Pain, 94, 133, 10.1016/S0304-3959(01)00408-0 Faucett, 1994, Differences in postoperative pain severity among four ethnic groups., J Pain Symptom Manage, 9, 383, 10.1016/0885-3924(94)90175-9 Fillingim, 1997, Ischemic but not thermal pain sensitivity varies across the menstrual cycle., Psychosom Med, 59, 512, 10.1097/00006842-199709000-00008 Franke, 1999, Human d-opioid receptor gene and susceptibility to heroin and alcohol dependence., Am J Med Genet, 88, 462, 10.1002/(SICI)1096-8628(19991015)88:5<462::AID-AJMG4>3.0.CO;2-S Gelernter, 2000, Variant detection at the d opioid receptor (OPRD1) locus and population genetics of a novel variant affecting protein sequence., Hum Genet, 107, 86, 10.1007/s004390000340 Giles, 2000, Sex differences in pain and analgesia., Pain Rev, 7, 181 Gomes, 2000, Heterodimerization of m and d opioid receptors: a role in opiate synergy., J Neurosci, 20, 1 Guzick, 2001, Sperm morphology, motility, and concentration in fertile and infertile men., N Engl J Med, 345, 1388, 10.1056/NEJMoa003005 Hayes, 2000, Cloning and functional expression of a human orthologue of rat vanilloid receptor-1., Pain, 88, 205, 10.1016/S0304-3959(00)00353-5 Heath, 1994, Testing a model for the genetic structure of personality: a comparison of the personality systems of Cloninger and Eysenck., J Pers Soc Psychol, 66, 762, 10.1037/0022-3514.66.4.762 Jordt, 2004, Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1., Nature, 427, 260, 10.1038/nature02282 Keogh, 2001, Investigating the effects of anxiety sensitivity and coping on the perception of cold pressor pain in healthy women., Eur J Pain, 5, 11, 10.1053/eujp.2000.0210 Korshunov, 2000, Immunohistochemical markers for intracranial ependymoma recurrence. An analysis of 88 cases., J Neurol Sci, 177, 72, 10.1016/S0022-510X(00)00347-6 Kupers, 1997, Sex differences in pain: and now for something completely different., Behav Brain Sci, 20, 455, 10.1017/S0140525X97391493 LaForge, 2000, Opioid receptor and peptide gene polymorphisms: potential implications for addictions., Eur J Pharm, 410, 249, 10.1016/S0014-2999(00)00819-0 Lachman, 1996, Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders., Pharmacogenetics, 6, 243, 10.1097/00008571-199606000-00007 Lariviere, 2002, Heritability of nociception. III. Genetic relationships among commonly used assays of nociception and hypersensitivity., Pain, 97, 75, 10.1016/S0304-3959(01)00492-4 Lavrac, 1999, Selected techniques for data mining in medicine., Artif Intell Med, 16, 3, 10.1016/S0933-3657(98)00062-1 Lawlis, 1984, Ethnic and sex differences in response to clinical and induced pain in chronic spinal pain patients., Spine, 9, 751, 10.1097/00007632-198410000-00017 Lewis, 1989, GENESTAT for microcomputers., ASPT Newslett, 2, 15 MacGregor, 2002, Using twin studies to label disease as genetic or environmental is inappropriate., Br Med J, 324, 1100, 10.1136/bmj.324.7345.1100/b Marshall, 2001, The use of classification and regression trees in clinical epidemiology., J Clin Epidemiol, 54, 603, 10.1016/S0895-4356(00)00344-9 Mayer, 1997, Association between a delta opioid receptor gene polymorphism and heroin dependence in man., NeuroReport, 8, 2547, 10.1097/00001756-199707280-00025 McKemy, 2002, Identification of a cold receptor reveals a general role for TRP channels in thermosensation., Nature, 416, 52, 10.1038/nature719 Milligan, 2001, Protein-protein interactions at G-protein-coupled receptors., Trends Pharmacol Sci, 22, 513, 10.1016/S0165-6147(00)01801-0 Mitrovic, 2002, Contribution of GIRK2-mediated postsynaptic signaling to opiate and a2-adrenergic analgesia and analgesic sex differences., Proc Natl Acad Sci USA, 100, 271, 10.1073/pnas.0136822100 Mogil, 1997, Genetic sensitivity to hot-plate nociception in DBA2J and C57BL6J inbred mouse strains: possible sex-specific mediation by d2-opioid receptors., Pain, 70, 267, 10.1016/S0304-3959(97)03333-2 Mogil, 2000, Sex differences in thermal nociception and morphine antinociception in rodents depend on genotype., Neurosci Biobehav Rev, 24, 375, 10.1016/S0149-7634(00)00015-4 Munafo, 1997, Associate learning and pain? Why stop there?, Behav Brain Sci, 20, 459, 10.1017/S0140525X97441493 Mannisto, 1999, Catechol-O-methyltransferase (COMT) biochemistry, molecular biology, pharmacology, and clinical Efficacy of the new selective COMT Inhibitors., Phamarcol Rev, 51, 593 Naliboff, 2003, Sex-related differences in IBS patients: central processing of visceral stimuli., Gastroenterology, 124, 1738, 10.1016/S0016-5085(03)00400-1 Ohayon, 2003, Using chronic pain to predict depressive morbidity in the general population., Arch Gen Psychiatry, 60, 39, 10.1001/archpsyc.60.1.39 Pearson, 2003, DNA: beyond the double helix., Nature, 421, 310, 10.1038/421310a Put, 2003, Classification and regression tree analysis for molecular descriptor selection and retention prediction in chromatographic quantitative structure-retention relationship studies., J Chromatogr A, 988, 261, 10.1016/S0021-9673(03)00004-9 Rhudy, 2000, Fear and anxiety: divergent effects on human pain thresholds., Pain, 84, 65, 10.1016/S0304-3959(99)00183-9 Rosier, 2002, Reproducibility of pain measurement and pain perception., Pain, 98, 205, 10.1016/S0304-3959(02)00048-9 Scholz, 2002, Can we conquer pain?, Nat Neurosci, 5, 1062, 10.1038/nn942 Schumacher, 1984, Anxiety, pain experience, and pain report: a signal-detection study., Percept Mot Skills, 58, 339, 10.2466/pms.1984.58.2.339 Smirnov, 2001, d-opioid receptor gene: effect of Sp1 factor on transcriptional regulation in vivo., Mol Pharmacol, 60, 331, 10.1124/mol.60.2.331 Story, 2003, ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures., Cell, 112, 819, 10.1016/S0092-8674(03)00158-2 Sullivan, 2003, Fatigue in a community sample of twins., Psychol Med, 33, 263, 10.1017/S0033291702007031 Turk, 2002, Remember the distinction between malignant and benign pain? Well forget it., Clin J Pain, 18, 75, 10.1097/00002508-200203000-00001 Veith, 1984, Plasma beta-endorphin, pain thresholds and anxiety levels across the human menstrual cycle., Physiol Behav, 32, 31, 10.1016/0031-9384(84)90065-9 Viswanath, 2003, Opposite thermosensor in fruit fly and mouse., Nature, 423, 822, 10.1038/423822a Xie, 1997, GA1947 Polymorphism in catechol-O-methyltransferase(COMT) gene in Parkinsons disease., Mov Disord, 12, 426, 10.1002/mds.870120325 Xu, 2002, Relationship of the delta-opioid receptor gene to heroin abuse in a large Chinese casecontrol sample., Am J Med Genet, 110, 45, 10.1002/ajmg.10374 Zhu, 1999, Retention of supraspinal delta-like analgesia and loss of morphine tolerance in d opioid receptor knockout mice., Neuron, 24, 243, 10.1016/S0896-6273(00)80836-3 Zubieta, 2003, COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor., Science, 299, 1240, 10.1126/science.1078546