Feasibility of [18F]-RGD for ex vivo imaging of atherosclerosis in detection of αvβ3 integrin expression

Naghavi, 2003, From vulnerable plaque to vulnerable patient: A call for new definitions and risk assessment strategies: Part I, Circulation, 108, 1664, 10.1161/01.CIR.0000087480.94275.97

Virmani, 2005, Atherosclerotic plaque progression and vulnerability to rupture: Angiogenesis as a source of intraplaque hemorrhage, Arterioscler Thromb Vasc Biol, 25, 2054, 10.1161/01.ATV.0000178991.71605.18

Nagengast, 2007, In vivo VEGF imaging with radiolabeled bevacizumab in a human ovarian tumor xenograft, J Nucl Med, 48, 1313, 10.2967/jnumed.107.041301

Cai, 2006, PET of vascular endothelial growth factor receptor expression, J Nucl Med, 47, 2048

Lam, 2013, Single-chain VEGF/Cy5.5 targeting vegf receptors to indicate atherosclerotic plaque instability, Mol Imaging Biol, 15, 250, 10.1007/s11307-012-0594-7

Schnell, 2009, Imaging of integrin alpha(v)beta(3) expression in patients with malignant glioma by [18F] galacto-RGD positron emission tomography, Neuro Oncol, 11, 861, 10.1215/15228517-2009-024

Hoshiga, 1995, Alpha-v beta-3 integrin expression in normal and atherosclerotic artery, Circ Res, 77, 1129, 10.1161/01.RES.77.6.1129

Liu, 2006, Radiolabeled multimeric cyclic RGD peptides as integrin alphavbeta3 targeted radiotracers for tumor imaging, Mol Pharm, 3, 472, 10.1021/mp060049x

McParland, 2008, The biodistribution and radiation dosimetry of the Arg-Gly-Asp peptide 18F-AH111585 in healthy volunteers, J Nucl Med, 49, 1664, 10.2967/jnumed.108.052126

Beer, 2008, Comparison of integrin alphaVbeta3 expression and glucose metabolism in primary and metastatic lesions in cancer patients: A PET study using 18F-galacto-RGD and 18F-FDG, J Nucl Med, 49, 22, 10.2967/jnumed.107.045864

Razavian, 2011, Integrin-targeted imaging of inflammation in vascular remodeling, Arterioscler Thromb Vasc Biol, 31, 2820, 10.1161/ATVBAHA.111.231654

Laitinen, 2009, Evaluation of alphavbeta3 integrin-targeted positron emission tomography tracer 18F-galacto-RGD for imaging of vascular inflammation in atherosclerotic mice, Circ Cardiovasc Imaging, 2, 331, 10.1161/CIRCIMAGING.108.846865

Masteling, 2011, High-resolution imaging of human atherosclerotic carotid plaques with micro18F-FDG PET scanning exploring plaque vulnerability, J Nucl Cardiol, 18, 1066, 10.1007/s12350-011-9460-2

Golestani, 2013, Feasibility of vascular endothelial growth factor imaging in human atherosclerotic plaque using (89)Zr-bevacizumab positron emission tomography, Mol Imaging, 12, 235, 10.2310/7290.2012.00034

Gaertner, 2012, Radiolabelled RGD peptides for imaging and therapy, Eur J Nucl Med Mol Imaging, 39, S126, 10.1007/s00259-011-2028-1

Narula, 2013, Histopathologic characteristics of atherosclerotic coronary disease and implications of the findings for the invasive and noninvasive detection of vulnerable plaques, J Am Coll Cardiol, 61, 1041, 10.1016/j.jacc.2012.10.054

Ribatti, 2008, Inflammatory angiogenesis in atherogenesis—A double-edged sword, Ann Med, 40, 606, 10.1080/07853890802186913

Kenny, 2008, Phase I trial of the positron-emitting Arg-Gly-Asp (RGD) peptide radioligand 18F-AH111585 in breast cancer patients, J Nucl Med, 49, 879, 10.2967/jnumed.107.049452

Haubner, 2005, Noninvasive visualization of the activated alphavbeta3 integrin in cancer patients by positron emission tomography and [18F]galacto-RGD, PLoS Med, 2, e70, 10.1371/journal.pmed.0020070

Doss, 2012, Biodistribution and radiation dosimetry of the integrin marker 18F-RGD-K5 determined from whole-body PET/CT in monkeys and humans, J Nucl Med, 53, 787, 10.2967/jnumed.111.088955

Verjans, 2010, Early molecular imaging of interstitial changes in patients after myocardial infarction: Comparison with delayed contrast-enhanced magnetic resonance imaging, J Nucl Cardiol, 17, 1065, 10.1007/s12350-010-9268-5

Haubner, 2001, Noninvasive imaging of alpha(v)beta3 integrin expression using 18F-labeled RGD-containing glycopeptide and positron emission tomography, Cancer Res, 61, 1781

Meerwaldt, 2010, PET/SPECT imaging: From carotid vulnerability to brain viability, Eur J Radiol, 74, 104, 10.1016/j.ejrad.2009.01.034

West, 2010, Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands, Nature, 467, 972, 10.1038/nature09421

Holm, 2009, Atherosclerotic plaque development and instability: A dual role for VEGF, Ann Med, 41, 257, 10.1080/07853890802516507

Chen, 2009, Emerging role of FDG-PET/CT in assessing atherosclerosis in large arteries, Eur J Nucl Med Mol Imaging, 36, 144, 10.1007/s00259-008-0947-2

Razavian, 2011, Atherosclerosis plaque heterogeneity and response to therapy detected by in vivo molecular imaging of matrix metalloproteinase activation, J Nucl Med, 52, 1795, 10.2967/jnumed.111.092379

Razansky, 2012, Multispectral optoacoustic tomography of matrix metalloproteinase activity in vulnerable human carotid plaques, Mol Imaging Biol, 14, 277, 10.1007/s11307-011-0502-6