Genetic Disruption of Circadian Rhythms in the Suprachiasmatic Nucleus Causes Helplessness, Behavioral Despair, and Anxiety-like Behavior in Mice

Biological Psychiatry - Tập 80 - Trang 827-835 - 2016
Dominic Landgraf1,2, Jaimie E. Long1,2, Christophe D. Proulx3, Rita Barandas1,2,4,5, Roberto Malinow3, David K. Welsh1,2
1Veterans Affairs San Diego Healthcare System, San Diego
2Department of Psychiatry and Center for Circadian Biology, University of California, San Diego, La Jolla, California
3Department of Neurosciences, University of California, San Diego, La Jolla, California
4Department of Psychiatry, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, University of Lisbon, Lisbon, Portugal
5Faculty of Medicine, University of Lisbon, Lisbon, Portugal

Tài liệu tham khảo

Welsh, 2010, Suprachiasmatic nucleus: Cell autonomy and network properties, Annu Rev Physiol, 72, 551, 10.1146/annurev-physiol-021909-135919 Hattar, 2006, Central projections of melanopsin-expressing retinal ganglion cells in the mouse, J Comp Neurol, 497, 326, 10.1002/cne.20970 Husse, 2014, The light-dark cycle controls peripheral rhythmicity in mice with a genetically ablated suprachiasmatic nucleus clock, FASEB J, 28, 4950, 10.1096/fj.14-256594 Kiessling, 2014, Light stimulates the mouse adrenal through a retinohypothalamic pathway independent of an effect on the clock in the suprachiasmatic nucleus, PloS One, 9, e92959, 10.1371/journal.pone.0092959 Oster, 2006, The circadian rhythm of glucocorticoids is regulated by a gating mechanism residing in the adrenal cortical clock, Cell Metab, 4, 163, 10.1016/j.cmet.2006.07.002 Ishida, 2005, Light activates the adrenal gland: timing of gene expression and glucocorticoid release, Cell Metab, 2, 297, 10.1016/j.cmet.2005.09.009 Boyce, 2010, Circadian rhythms and depression, Aust Fam Physician, 39, 307 Schnell, 2014, Rhythm and mood: Relationships between the circadian clock and mood-related behavior, Behav Neurosci, 128, 326, 10.1037/a0035883 McCarthy, 2012, Cellular circadian clocks in mood disorders, J Biol Rhythms, 27, 339, 10.1177/0748730412456367 McClung, 2007, Circadian genes, rhythms and the biology of mood disorders, Pharmacol Ther, 114, 222, 10.1016/j.pharmthera.2007.02.003 Kronfeld-Schor, 2012, Circadian rhythms and depression: Human psychopathology and animal models, Neuropharmacology, 62, 101, 10.1016/j.neuropharm.2011.08.020 Li, 2013, Circadian patterns of gene expression in the human brain and disruption in major depressive disorder, Proc Natl Acad Sci U S A, 110, 9950, 10.1073/pnas.1305814110 Landgraf, 2014, The role of the circadian clock in animal models of mood disorders, Behav Neurosci, 128, 344, 10.1037/a0036029 Ushijima, 2006, Chronobiological disturbances with hyperthermia and hypercortisolism induced by chronic mild stress in rats, Behav Brain Res, 173, 326, 10.1016/j.bbr.2006.06.038 Gorka, 1996, Effect of chronic mild stress on circadian rhythms in the locomotor activity in rats, Pharmacol Biochem Behav, 54, 229, 10.1016/0091-3057(95)02173-6 Logan, 2015, Chronic stress induces brain region-specific alterations of molecular rhythms that correlate with depression-like behavior in mice, Biol Psychiatry, 78, 249, 10.1016/j.biopsych.2015.01.011 Savalli, 2014, Diurnal oscillation of amygdala clock gene expression and loss of synchrony in a mouse model of depression, Int J Neuropsychopharmacol. Dec 11, 18 Rosenberg, 2011, Is shift work making your patient sick? Emerging theories and therapies for treating shift work disorder, Postgrad Med, 123, 106, 10.3810/pgm.2011.09.2465 Monje, 2011, Constant darkness induces IL-6-dependent depression-like behavior through the NF-kappaB signaling pathway, J Neurosci, 31, 9075, 10.1523/JNEUROSCI.1537-11.2011 Dulcis, 2013, Neurotransmitter switching in the adult brain regulates behavior, Science, 340, 449, 10.1126/science.1234152 Gonzalez, 2008, Light deprivation damages monoamine neurons and produces a depressive behavioral phenotype in rats, Proc Natl Acad Sci U S A, 105, 4898, 10.1073/pnas.0703615105 Tataroglu, 2004, Effect of lesioning the suprachiasmatic nuclei on behavioral despair in rats, Brain Res, 1001, 118, 10.1016/j.brainres.2003.11.063 Cryan, 2004, In search of a depressed mouse: Utility of models for studying depression-related behavior in genetically modified mice, Mol Psychiatry, 9, 326, 10.1038/sj.mp.4001457 Fernandez, 2014, Circadian rhythm. Dysrhythmia in the suprachiasmatic nucleus inhibits memory processing, Science, 346, 854, 10.1126/science.1259652 Yoo, 2004, PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues, Proc Natl Acad Sci U S A, 101, 5339, 10.1073/pnas.0308709101 Welsh, 2004, Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression, Curr Biol, 14, 2289, 10.1016/j.cub.2004.11.057 Landgraf, 2015, Dissociation of learned helplessness and fear conditioning in mice: a mouse model of depression, PloS One, 10, e0125892, 10.1371/journal.pone.0125892 Landgraf, 2015, Depression-like behaviour in mice is associated with disrupted circadian rhythms in nucleus accumbens and periaqueductal gray, Eur J Neurosci, 43, 1309, 10.1111/ejn.13085 Landgraf, 2014, Circadian clock and stress interactions in the molecular biology of psychiatric disorders, Curr Psychiatry Rep, 16, 483, 10.1007/s11920-014-0483-7 Souetre, 1989, Circadian rhythms in depression and recovery: Evidence for blunted amplitude as the main chronobiological abnormality, Psychiatry Res, 28, 263, 10.1016/0165-1781(89)90207-2 Buckley, 2010, A pilot study of the phase angle between cortisol and melatonin in major depression—a potential biomarker?, J Psychiatr Res, 44, 69, 10.1016/j.jpsychires.2009.06.012 Emens, 2009, Circadian misalignment in major depressive disorder, Psychiatry Res, 168, 259, 10.1016/j.psychres.2009.04.009 Kitamura, 2010, Evening preference is related to the incidence of depressive states independent of sleep-wake conditions, Chronobiol Int, 27, 1797, 10.3109/07420528.2010.516705 Pollak, 2010, Rodent models in depression research: Classical strategies and new directions, Ann Med, 42, 252, 10.3109/07853891003769957 Henn, 2005, Stress models of depression: Forming genetically vulnerable strains, Neurosci Biobehav Rev, 29, 799, 10.1016/j.neubiorev.2005.03.019 Edwards, 1990, Effects of bilateral adrenalectomy on the induction of learned helplessness behavior, Neuropsychopharmacology, 3, 109 Chover-Gonzalez, 2000, Onset and severity of inflammation in rats exposed to the learned helplessness paradigm, Rheumatology (Oxford), 39, 764, 10.1093/rheumatology/39.7.764 Toloknov, 1999, Blood corticosterone and resistance to hypoxia during operant learning and development of learned helplessness [in Russian], Biull Eksp Biol Med, 128, 29, 10.1007/BF02433312 Liu, 2007, Intercellular coupling confers robustness against mutations in the SCN circadian clock network, Cell., 129, 605, 10.1016/j.cell.2007.02.047 Barandas, 2015, Circadian clocks as modulators of metabolic comorbidity in psychiatric disorders, Curr Psychiatry Rep, 17, 98, 10.1007/s11920-015-0637-2