Treatment of whole blood (WB) and red blood cells (RBC) with S-303 inactivates pathogens and retains in vitro quality of stored RBC

Mohammed, 2008, Dengue virus in blood donations, Puerto Rico, 2005, Transfusion, 48, 1348, 10.1111/j.1537-2995.2008.01771.x Tambyah, 2008, Transfusion-Transmitted Dengue Infection Study Group. Dengue hemorrhagic fever transmitted by blood transfusion, N Eng J Med, 359, 1526, 10.1056/NEJMc0708673 Benjamin, 2007, The residual risk of sepsis: modeling the effect of concentration on bacterial detection in two-bottle culture systems and an estimation of false–negative culture rates, Transfusion, 47, 1381, 10.1111/j.1537-2995.2007.01326.x Yomtovian, 2007, Platelet bacterial contamination: assessing progress and identifying quandries in a rapidly evolving field, Transfusion, 47, 1340, 10.1111/j.1537-2995.2007.01402.x Leiby, 2006, Babesiosis and blood transfusion: flying under the radar, Vox Sang, 90, 157, 10.1111/j.1423-0410.2006.00740.x Triulzi, 2006, Fatal transfusion-associated graft-versus-host disease in an immunocompetent recipient of a volunteer unit of red cells, Transfusion, 6, 885, 10.1111/j.1537-2995.2006.00819.x Nichols, 2003, Transfusion-transmitted cytomegalovirus infection after receipt of leukoreduced blood products, Blood, 101, 4195, 10.1182/blood-2002-10-3143 Klein, 2007, Pathogen inactivation: making decisions about new technologies: report of a consensus conference, Transfusion, 47, 2338, 10.1111/j.1537-2995.2007.01512.x Bracey Webert KE, Cserti CM, Hannon J, Lin Y, Pavenski K, Pendergrast JM, et al. Proceedings of a consensus conference: pathogen inactivation – making decisions about new technologies. Transfusion Med Reviews 2008;22:1–34. Charrel, 2007, Chikungunya outbreaks – the globalization of vectorborne diseases, N Engl J Med, 356, 769, 10.1056/NEJMp078013 Brouard, 2008, Estimated risk of Chikungunya viremic blood donation during an epidemic on Reunion Island in the Indian Ocean, 2005 to 2007, Transfusion, 48, 1333, 10.1111/j.1537-2995.2008.01646.x Enserink, 2008, A mosquito goes global, Science, 320, 864, 10.1126/science.320.5878.864 Osselaer, 2008, An active haemovigilance programme characterizing the safety profile of 7437 platelet transfusions prepared with amotosalen photochemical treatment, Vox Sang, 94, 315, 10.1111/j.1423-0410.2007.01035.x Osselaer, 2008, A prospective observational cohort safety study of 5,106 platelet transfusions using components prepared with photochemcial pathogen inactivation treatment, Transfusion, 48, 1061, 10.1111/j.1537-2995.2008.01643.x Osselaer, 2009, Universal adoption of pathogen inactivation of platelet components: impact on platelet and red blood cell component use, Transfusion, 49, 1412, 10.1111/j.1537-2995.2009.02151.x Rasonglès, 2009, Transfusion of platelet components prepared with photochemical pathogen inactivation treatment during a Chikungunya Virus epidemic in Ile de La Reunion, Transfusion, 49, 1083, 10.1111/j.1537-2995.2009.02111.x Singh, 2006, Photochemical treatment of plasma with amotosalen and UVA light inactivates pathogens while retaining coagulation function, Transfusion, 46, 1168, 10.1111/j.1537-2995.2006.00867.x Cazenave, 2008, An active hemovigilance program utilizing and EDC system to assess safety of 2994 plasma transfusions prepared with the INTERCEPT Blood System, Transfusion, 48, 29A Bryant, 2007, Pathogen inactivation: the definitive safeguard for the blood supply, Arch Pathol Lab Med, 131, 719, 10.5858/2007-131-719-PITDSF Rios, 2006, Viability of red cells prepared with S-303 pathogen inactivation treatment, Transfusion, 46, 1778, 10.1111/j.1537-2995.2006.00973.x Benjamin, 2005, Therapeutic efficacy and safety of red blood cells treated with a chemical process (S-303) for pathogen inactivation: a Phase III clinical trial in cardiac surgery patients, Transfusion, 45, 1739, 10.1111/j.1537-2995.2005.00583.x Cancelas, 2008, A randomized, controlled, 2-period crossover study of recovery and lifespan of radiolabeled autologous 35-day-old red blood cells prepared with a modified S-303 treatment for pathogen inactivation, Vox Sang, 95, 2A Beutler, 2000, Back to the future in RBC preservation, Transfusion, 40, 893, 10.1046/j.1537-2995.2000.40080893.x Lew, 2003, Excess hemoglobin digestion and the osmotic stability of Plasmodium falciparum-infected red blood cells, Blood, 101, 4189, 10.1182/blood-2002-08-2654 Lin, 1997, Photochemical inactivation of viruses and bacteria in platelet concentrates by use of a novel psoralen and long-wavelength ultraviolet light, Transfusion, 37, 423, 10.1046/j.1537-2995.1997.37497265344.x Högman, 1985, Studies on the mechanism of human red cell loss of viability during storage at +4 degrees C in vitro. I. Cell shape and total adenylate concentration as determinant factors for posttransfusion survival, Vox Sang, 48, 257, 10.1111/j.1423-0410.1985.tb00181.x American Association of Blood Banks, 2005 Council of Europe, 2007 Clark, 1981, Separate mechanisms of deformability loss in ATP-depleted and Ca-loaded erythrocytes, J Clin Invest, 67, 531, 10.1172/JCI110063 Farges, 2002, Viscoelastic and biochemical properties of erythrocytes during storage with SAG-M at +4 degrees C, Clin Hemorheol Microcirc, 27, 1 d'Onofrio, 1995, Simultaneous measurement of reticulocyte and red blood cell indices in healthy subjects and patients with microcytic and nacrocytic anemia, Blood, 85, 818, 10.1182/blood.V85.3.818.bloodjournal853818 Gulati, 2002, Changes in automated complete blood cell count and differential leukocyte count results induced by storage of blood at room temperature, Arch Pathol Lab Med, 126, 336, 10.5858/2002-126-0336-CIACBC Wagner, 1994, Transfusion-associated bacterial sepsis, Clin Microbiol Rev, 7, 290, 10.1128/CMR.7.3.290 Hillyer, 2003, Bacterial contamination of blood components: risks, strategies, and regulation: joint ASH and AABB educational session in transfusion medicine. Hematology Am Soc Hematol Educ Program, 575