Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects

Immunity - Tập 45 - Trang 931-943 - 2016
Romain Daillère1,2,3, Marie Vétizou1,2,3, Nadine Waldschmitt4, Takahiro Yamazaki1,2, Christophe Isnard5,6, Vichnou Poirier-Colame1,2,3, Connie P.M. Duong1,2,7, Caroline Flament1,2,7, Patricia Lepage8, Maria Paula Roberti1,2,7, Bertrand Routy1,2,3, Nicolas Jacquelot1,2,3, Lionel Apetoh9,10,11, Sonia Becharef1,2,7, Sylvie Rusakiewicz1,2,7, Philippe Langella8, Harry Sokol8,12,13, Guido Kroemer14,15,16,17,18,19, David Enot1,15, Antoine Roux1,2,3,18
1Institut de Cancérologie Gustave Roussy Cancer Campus (GRCC), 114 rue Edouard Vaillant, Villejuif, 94805, France
2Institut National de la Santé Et de la Recherche Medicale (INSERM), U1015, GRCC, Villejuif, 94805, France
3University of Paris-Saclay, Kremlin Bicêtre, 94270, France
4University Lille, CNRS, Inserm, CHRU Lille, Institut Pasteur de Lille, U1019-UMR 8204-CIIL, Centre d’Infection et d’Immunité de Lille, 59000 Lille, France
5Université de Caen Basse-Normandie, EA4655 U2RM (Équipe Antibio-Résistance), Caen, 14033, France
6CHU de Caen, Service de Microbiologie, Caen, 14033, France
7Center of Clinical Investigations in Biotherapies of Cancer (CICBT) 1428, Villejuif, 94805, France
8Micalis Institute, INRA, AgroParisTech, Université Paris-Saclay, 78350, Jouy-en-Josas, France
9Lipids, Nutrition, Cancer, INSERM, U866, Dijon, 21078, France
10Department of Medicine, Université de Bourgogne Franche-Comté, Dijon, 21078, France
11Department of Oncology, Centre Georges François Leclerc, Dijon, 21000, France
12AVENIR Team Gut Microbiota and Immunity, ERL, INSERM U 1157/UMR 7203, Faculté de Médecine, Saint-Antoine, Université Pierre et Marie Curie (UPMC), Paris, 75012, France
13Service de Gastroentérologie, Hôpital Saint-Antoine, Assistance Publique—Hôpitaux de Paris (APHP), Paris, 75012, France
14INSERM, U848, 94805 Villejuif, France
15Metabolomics Platform, Institut Gustave Roussy, Villejuif, 94805, France
16Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM U 1138, Paris, 75006, France
17Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, 75015, France
18Université Paris Descartes, Sorbonne Paris Cité, Paris 75006, France
19Karolinska Institute, Department of Women’s and Children’s Health, Karolinska University Hospital, Stockholm 17176, Sweden

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