Tacrolimus (FK506) prevents early retinal neovascularization in streptozotocin-induced diabetic mice

International Immunopharmacology - Tập 14 - Trang 606-612 - 2012
Landi Su1,2, Jing Ji2, Jieyu Bian2, Yuxuan Fu2, Yingbin Ge2, Zhilan Yuan3
1Medicine Division, Yangzhou Vocational College of Environment Resources, Yangzhou 225127, China
2Department of Physiology, Nanjing Medical University, Nanjing 210029, China
3Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China

Tài liệu tham khảo

Wild, 2004, Global prevalence of diabetes: estimates for the year 2000 and projections for 2030, Diabetes Care, 27, 1047, 10.2337/diacare.27.5.1047 Watkins, 2003, ABC of diabetes-retinopathy, BMJ, 326, 924, 10.1136/bmj.326.7395.924 Murdoch, 2005, Hypoxia regulates macrophage functions in inflammation, J Immunol, 175, 6257, 10.4049/jimmunol.175.10.6257 Tang, 2011, Inflammation in diabetic retinopathy, Prog Retin Eye Res, 30, 343, 10.1016/j.preteyeres.2011.05.002 Adamis, 2008, Immunological mechanisms in the pathogenesis of diabetic retinopathy, Semin Immunopathol, 30, 65, 10.1007/s00281-008-0111-x Joussen, 2004, A central role for inflammation in the pathogenesis of diabetic retinopathy, FASEB J, 18, 1450, 10.1096/fj.03-1476fje Adamis, 1999, Angiogenesis and ophthalmic disease, Angiogenesis, 3, 9, 10.1023/A:1009071601454 Ishida, 2003, VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization, J Exp Med, 198, 483, 10.1084/jem.20022027 Nagai, 2007, Suppression of diabetes-induced retinal in flammation by blocking the angiotensin II type 1 receptor or its downstream nuclear factor-kappaB pathway, Invest Ophthalmol Vis Sci, 48, 4342, 10.1167/iovs.06-1473 Todo, 1990, Liver, kidney, and thoracic organ transplantation under FK 506, Ann Surg, 212, 295, 10.1097/00000658-199009000-00008 Baumgart, 2006, Tacrolimus is safe and effective in patients with severe steroid-refractory or steroid-dependent inflammatory bowel disease—a long-term follow-up, Am J Gastroenterol, 101, 1048, 10.1111/j.1572-0241.2006.00524.x Thestrup-Pedersen, 2003, Tacrolimus treatment of atopic eczema/dermatitis syndrome, Curr Opin Allergy Clin Immunol, 3, 359, 10.1097/00130832-200310000-00007 Zeyda, 2007, Impairment of T cell interactions with antigen-presenting cells by immunosuppressive drugs reveals involvement of calcineurin and NF-kappaB in immunological synapse formation, J Leukoc Biol, 81, 319, 10.1189/jlb.0606378 Du, 2009, Suppression of NF-kappaB by cyclosporin a and tacrolimus (FK506) via induction of the C/EBP family: implication for unfolded protein response, J Immunol, 182, 7201, 10.4049/jimmunol.0801772 Yoshino, 2010, Immunosuppressive effects of tacrolimus on macrophages ameliorate experimental colitis, Inflamm Bowel Dis, 16, 2022, 10.1002/ibd.21318 Nakamura-Yanagidaira, 2011, Development of spontaneous neuropathy in NF-κBp50-deficient mice by calcineurin-signal involving impaired NF-κB activation, Mol Vis, 17, 2157 Sharma, 1985, A morphologic and autoradiographic study of cell death and regeneration in the retinal microvasculature of normal and diabetic rats, Am J Ophthalmol, 100, 51, 10.1016/S0002-9394(14)74982-7 Mizutani, 1996, Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy, J Clin Invest, 97, 2883, 10.1172/JCI118746 Oh-i, 2007, Intravitreal injection of Tacrolimus (FK506) suppresses ongoing experimental autoimmune uveoretinitis in rats, Br J Ophthalmol, 91, 237, 10.1136/bjo.2006.103168 Spierer, 2005, An increase in superoxide dismutase ameliorates oxygen-induced retinopathy, Eye (Lond), 19, 86, 10.1038/sj.eye.6701424 Otani, 2004, Rescue of retinal degeneration by intravitreally injected adult bone marrow-derived lineage-negative hematopoietic stem cells, J Clin Invest, 114, 765, 10.1172/JCI200421686 Jockovich, 2008, Heterogeneous tumor vasculature in retinoblastoma: implications for vessel targeting therapy, Retina, 28, S81, 10.1097/IAE.0b013e318150d6f0 Tsai, 2009, Effect of N-acetylcysteine on the early expression of inflammatory markers in the retina and plasma of diabetic rats, Clin Experiment Ophthalmol, 37, 223, 10.1111/j.1442-9071.2009.02000.x Schnedl, 1994, STZ transport and cytotoxicity: specific enhancement in GLUT2-expressing cells, Diabetes, 43, 1326, 10.2337/diab.43.11.1326 Satofuka, 2009, (Pro)renin receptor-mediated signal transduction and tissue renin–angiotensin system contribute to diabetes-induced retinal inflammation, Diabetes, 58, 1625, 10.2337/db08-0254 Brockman, 1995, Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation, Mol Cell Biol, 15, 2809, 10.1128/MCB.15.5.2809 Brown, 1995, Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation, Science, 267, 1485, 10.1126/science.7878466 DiDonato, 1996, Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation, Mol Cell Biol, 16, 1295, 10.1128/MCB.16.4.1295 Baldwin, 1996, The NF-kappa B and I kappa B proteins: new discoveries and insights, Annu Rev Immunol, 14, 649, 10.1146/annurev.immunol.14.1.649 Yoshida, 1999, Suppression of retinal neovascularization by the NF-kappaB inhibitor pyrrolidine dithiocarbamate in mice, Invest Ophthalmol Vis Sci, 40, 1624 Krady, 2005, Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy, Diabetes, 54, 1559, 10.2337/diabetes.54.5.1559 Wang, 2006, Nuclear factor-kappaB p65 and upregulation of interleukin-6 in retinal ischemia/reperfusion injury in rats, Brain Res, 1081, 211, 10.1016/j.brainres.2006.01.077