Intrinsic Gastrointestinal Macrophages: Their Phenotype and Role in Gastrointestinal Motility

Cellular and Molecular Gastroenterology and Hepatology - Tập 2 - Trang 120-130.e1 - 2016
Gianluca Cipriani1, Simon J. Gibbons1, Purna C. Kashyap1, Gianrico Farrugia1
1Enteric NeuroScience Program, Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, Rochester, Minnesota

Tài liệu tham khảo

Hume, 1984, The mononuclear phagocyte system of the mouse defined by immunohistochemical localisation of antigen F4/80: macrophages associated with epithelia, Anat Rec, 210, 503, 10.1002/ar.1092100311 Lee, 1985, Quantitative analysis of total macrophage content in adult mouse tissues. Immunochemical studies with monoclonal antibody F4/80, J Exp Med, 161, 475, 10.1084/jem.161.3.475 Bain, 2014, Macrophages in intestinal homeostasis and inflammation, Immunol Rev, 260, 102, 10.1111/imr.12192 Smythies, 2005, Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity, J Clin Invest, 115, 66, 10.1172/JCI200519229 Gordon, 2005, Monocyte and macrophage heterogeneity, Nat Rev Immunol, 5, 953, 10.1038/nri1733 Ginhoux, 2010, Fate mapping analysis reveals that adult microglia derive from primitive macrophages, Science, 330, 841, 10.1126/science.1194637 van Furth, 1968, The origin and kinetics of mononuclear phagocytes, J Exp Med, 128, 415, 10.1084/jem.128.3.415 Hashimoto, 2013, Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes, Immunity, 38, 792, 10.1016/j.immuni.2013.04.004 Ajami, 2007, Local self-renewal can sustain CNS microglia maintenance and function throughout adult life, Nat Neurosci, 10, 1538, 10.1038/nn2014 Rivollier, 2012, Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon, J Exp Med, 209, 139, 10.1084/jem.20101387 Bain, 2014, Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice, Nat Immunol, 15, 929, 10.1038/ni.2967 Bain, 2013, Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors, Mucosal Immunol, 6, 498, 10.1038/mi.2012.89 Mikkelsen, 1995, Macrophages in the external muscle layers of mammalian intestines, Histol Histopathol, 10, 719 Kalff, 1998, Leukocytes of the intestinal muscularis: their phenotype and isolation, J Leukoc Biol, 63, 683, 10.1002/jlb.63.6.683 Mikkelsen, 1999, Op/op mice defective in production of functional colony-stimulating factor-1 lack macrophages in muscularis externa of the small intestine, Cell Tissue Res, 295, 485, 10.1007/s004410051254 Mikkelsen, 2008, The macrophage system in the intestinal muscularis externa during inflammation: an immunohistochemical and quantitative study of osteopetrotic mice, Histochem Cell Biol, 130, 363, 10.1007/s00418-008-0423-x Mikkelsen, 1985, Macrophage-like cells in the muscularis externa of mouse small intestine, Anat Rec, 213, 77, 10.1002/ar.1092130111 Hori, 2008, MCP-1 targeting inhibits muscularis macrophage recruitment and intestinal smooth muscle dysfunction in colonic inflammation, Am J Physiol Cell Physiol, 294, C391, 10.1152/ajpcell.00056.2007 Linden, 2005, Indiscriminate loss of myenteric neurones in the TNBS-inflamed guinea-pig distal colon, Neurogastroenterol Motil, 17, 751, 10.1111/j.1365-2982.2005.00703.x Bernard, 2014, Association of low numbers of CD206-positive cells with loss of ICC in the gastric body of patients with diabetic gastroparesis, Neurogastroenterol Motil, 26, 1275, 10.1111/nmo.12389 Choi, 2010, CD206-positive M2 macrophages that express heme oxygenase-1 protect against diabetic gastroparesis in mice, Gastroenterology, 138, 2399, 10.1053/j.gastro.2010.02.014 Yoshida, 1990, The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene, Nature, 345, 442, 10.1038/345442a0 Martinez, 2013, Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences, Blood, 121, e57, 10.1182/blood-2012-06-436212 Tamoutounour, 2012, CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis, Eur J Immunol, 42, 3150, 10.1002/eji.201242847 Geissmann, 2003, Blood monocytes consist of two principal subsets with distinct migratory properties, Immunity, 19, 71, 10.1016/S1074-7613(03)00174-2 Auffray, 2009, Blood monocytes: development, heterogeneity, and relationship with dendritic cells, Annu Rev Immunol, 27, 669, 10.1146/annurev.immunol.021908.132557 Muller, 2014, Crosstalk between muscularis macrophages and enteric neurons regulates gastrointestinal motility, Cell, 158, 300, 10.1016/j.cell.2014.04.050 Mills, 2000, M-1/M-2 macrophages and the Th1/Th2 paradigm, J Immunol, 164, 6166, 10.4049/jimmunol.164.12.6166 Martinez, 2014, The M1 and M2 paradigm of macrophage activation: time for reassessment, F1000Prime Rep, 6, 13, 10.12703/P6-13 Murray, 2014, Macrophage activation and polarization: nomenclature and experimental guidelines, Immunity, 41, 14, 10.1016/j.immuni.2014.06.008 Gross, 2014, Epigenetic silencing of the human NOS2 gene: rethinking the role of nitric oxide in human macrophage inflammatory responses, J Immunol, 192, 2326, 10.4049/jimmunol.1301758 Raes, 2005, Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells, J Immunol, 174, 6561, 10.4049/jimmunol.174.11.6561 Deng, 2012, IL-10 triggers changes in macrophage phenotype that promote muscle growth and regeneration, J Immunol, 189, 3669, 10.4049/jimmunol.1103180 Lee, 2002, Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice, Nat Med, 8, 240, 10.1038/nm0302-240 Grainger, 2013, Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection, Nat Med, 19, 713, 10.1038/nm.3189 Zigmond, 2012, Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells, Immunity, 37, 1076, 10.1016/j.immuni.2012.08.026 Kurihara, 1997, Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor, J Exp Med, 186, 1757, 10.1084/jem.186.10.1757 Boring, 1998, Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis, Nature, 394, 894, 10.1038/29788 Kanda, 2006, MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity, J Clin Invest, 116, 1494, 10.1172/JCI26498 Platt, 2010, An independent subset of TLR expressing CCR2-dependent macrophages promotes colonic inflammation, J Immunol, 184, 6843, 10.4049/jimmunol.0903987 Phillips, 2012, Macrophages associated with the intrinsic and extrinsic autonomic innervation of the rat gastrointestinal tract, Auton Neurosci, 169, 12, 10.1016/j.autneu.2012.02.004 Mikkelsen, 2010, Interstitial cells of Cajal, macrophages and mast cells in the gut musculature: morphology, distribution, spatial and possible functional interactions, J Cell Mol Med, 14, 818, 10.1111/j.1582-4934.2010.01025.x Nemethova, 2013, Nicotine attenuates activation of tissue resident macrophages in the mouse stomach through the beta2 nicotinic acetylcholine receptor, PLoS One, 8, e79264, 10.1371/journal.pone.0079264 Ho, 1997, Human monocytes and macrophages express substance P and neurokinin-1 receptor, J Immunol, 159, 5654, 10.4049/jimmunol.159.11.5654 Froh, 2002, Molecular evidence for a glycine-gated chloride channel in macrophages and leukocytes, Am J Physiol Gastrointest Liver Physiol, 283, G856, 10.1152/ajpgi.00503.2001 Marques-da-Silva, 2011, Purinergic receptor agonists modulate phagocytosis and clearance of apoptotic cells in macrophages, Immunobiology, 216, 1, 10.1016/j.imbio.2010.03.010 Coquenlorge, 2014, Modulation of lipopolysaccharide-induced neuronal response by activation of the enteric nervous system, J Neuroinflammation, 11, 202, 10.1186/s12974-014-0202-7 Green, 2004, Dextran sodium sulfate-induced colitis reveals nicotinic modulation of ion transport via iNOS-derived NO, Am J Physiol Gastrointest Liver Physiol, 287, G706, 10.1152/ajpgi.00076.2004 Hori, 2001, Upregulation of iNOS by COX-2 in muscularis resident macrophage of rat intestine stimulated with LPS, Am J Physiol Gastrointest Liver Physiol, 280, G930, 10.1152/ajpgi.2001.280.5.G930 Cowen, 2000, Restricted diet rescues rat enteric motor neurones from age related cell death, Gut, 47, 653, 10.1136/gut.47.5.653 Wu, 2003, Myenteric nitrergic neurons along the rat esophagus: evidence for regional and strain differences in age-related changes, Histochem Cell Biol, 119, 395, 10.1007/s00418-003-0526-3 Takahashi, 2000, Decreased expression of nitric oxide synthase in the colonic myenteric plexus of aged rats, Brain Res, 883, 15, 10.1016/S0006-8993(00)02867-5 Watkins, 2000, Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy, J Clin Invest, 106, 803, 10.1172/JCI8273C1 Kabouridis, 2015, Microbiota controls the homeostasis of glial cells in the gut lamina propria, Neuron, 85, 289, 10.1016/j.neuron.2014.12.037 Reigstad, 2015, Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells, FASEB J, 29, 1395, 10.1096/fj.14-259598 Round, 2009, The gut microbiota shapes intestinal immune responses during health and disease, Nat Rev Immunol, 9, 313, 10.1038/nri2515 Mortha, 2014, Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis, Science, 343, 1249288, 10.1126/science.1249288 Yano, 2015, Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis, Cell, 161, 264, 10.1016/j.cell.2015.02.047 de las Casas-Engel, 2013, Serotonin skews human macrophage polarization through HTR2B and HTR7, J Immunol, 190, 2301, 10.4049/jimmunol.1201133 Davies, 2013, Tissue-resident macrophages, Nat Immunol, 14, 986, 10.1038/ni.2705 Xue, 2014, Transcriptome-based network analysis reveals a spectrum model of human macrophage activation, Immunity, 40, 274, 10.1016/j.immuni.2014.01.006 Eskandari, 1999, LPS-induced muscularis macrophage nitric oxide suppresses rat jejunal circular muscle activity, Am J Physiol, 277, G478 Lodato, 1999, Roles of IL-1 and TNF in the decreased ileal muscle contractility induced by lipopolysaccharide, Am J Physiol, 276, G1356 Cannon, 1906, IV. The movements of the stomach and intestines in some surgical conditions, Ann Surg, 43, 512, 10.1097/00000658-190604000-00004 Bauer, 2002, Ileus in critical illness: mechanisms and management, Curr Opin Crit Care, 8, 152, 10.1097/00075198-200204000-00011 Boeckxstaens, 2009, Neuroimmune mechanisms in postoperative ileus, Gut, 58, 1300, 10.1136/gut.2008.169250 Bueno, 1978, Postoperative intestinal motility in dogs and sheep, Am J Dig Dis, 23, 682, 10.1007/BF01072352 Tache, 1993, Central action of TRH to induce vagally mediated gastric cytoprotection and ulcer formation in rats, J Clin Gastroenterol, 17, S58, 10.1097/00004836-199312001-00013 Turler, 2002, MCP-1 causes leukocyte recruitment and subsequently endotoxemic ileus in rat, Am J Physiol Gastrointest Liver Physiol, 282, G145, 10.1152/ajpgi.00263.2001 Tracey, 2007, Physiology and immunology of the cholinergic antiinflammatory pathway, J Clin Invest, 117, 289, 10.1172/JCI30555 Matteoli, 2014, A distinct vagal anti-inflammatory pathway modulates intestinal muscularis resident macrophages independent of the spleen, Gut, 63, 938, 10.1136/gutjnl-2013-304676 The, 2007, Activation of the cholinergic anti-inflammatory pathway ameliorates postoperative ileus in mice, Gastroenterology, 133, 1219, 10.1053/j.gastro.2007.07.022 Berthoud, 1991, Topography of efferent vagal innervation of the rat gastrointestinal tract, Am J Physiol, 260, R200 Stoffels, 2009, Role of interleukin 10 in murine postoperative ileus, Gut, 58, 648, 10.1136/gut.2008.153288 Motterlini, 2010, The therapeutic potential of carbon monoxide, Nat Rev Drug Discov, 9, 728, 10.1038/nrd3228 Moore, 2003, Inhaled carbon monoxide suppresses the development of postoperative ileus in the murine small intestine, Gastroenterology, 124, 377, 10.1053/gast.2003.50060 Stoffels, 2011, Anti-inflammatory role of glycine in reducing rodent postoperative inflammatory ileus, Neurogastroenterol Motil, 23, 76, 10.1111/j.1365-2982.2010.01603.x MacDonald, 2011, Regulation of homeostasis and inflammation in the intestine, Gastroenterology, 140, 1768, 10.1053/j.gastro.2011.02.047 Cader, 2013, Recent advances in inflammatory bowel disease: mucosal immune cells in intestinal inflammation, Gut, 62, 1653, 10.1136/gutjnl-2012-303955 Rutgeerts, 2009, Biological therapies for inflammatory bowel diseases, Gastroenterology, 136, 1182, 10.1053/j.gastro.2009.02.001 Vos, 2011, Anti-tumor necrosis factor-alpha antibodies induce regulatory macrophages in an Fc region-dependent manner, Gastroenterology, 140, 221, 10.1053/j.gastro.2010.10.008 Van den Brande, 2003, Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn's disease, Gastroenterology, 124, 1774, 10.1016/S0016-5085(03)00382-2 Vos, 2012, Regulatory macrophages induced by infliximab are involved in healing in vivo and in vitro, Inflamm Bowel Dis, 18, 401, 10.1002/ibd.21818 Maloy, 2011, Intestinal homeostasis and its breakdown in inflammatory bowel disease, Nature, 474, 298, 10.1038/nature10208 Li, 2008, Contextual regulation of inflammation: a duet by transforming growth factor-beta and interleukin-10, Immunity, 28, 468, 10.1016/j.immuni.2008.03.003 Fantini, 2009, Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression, Gastroenterology, 136, 1308, 10.1053/j.gastro.2008.12.053 Kuhn, 1993, Interleukin-10-deficient mice develop chronic enterocolitis, Cell, 75, 263, 10.1016/0092-8674(93)80068-P Huhn, 1997, Pharmacodynamics of subcutaneous recombinant human interleukin-10 in healthy volunteers, Clin Pharmacol Ther, 62, 171, 10.1016/S0009-9236(97)90065-5 Moore, 2001, Interleukin-10 and the interleukin-10 receptor, Annu Rev Immunol, 19, 683, 10.1146/annurev.immunol.19.1.683 Rakoff-Nahoum, 2006, Role of toll-like receptors in spontaneous commensal-dependent colitis, Immunity, 25, 319, 10.1016/j.immuni.2006.06.010 Hammer, 2011, Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis, Nat Immunol, 12, 1184, 10.1038/ni.2135 Siddiqui, 2010, E-cadherin marks a subset of inflammatory dendritic cells that promote T cell-mediated colitis, Immunity, 32, 557, 10.1016/j.immuni.2010.03.017 Brierley, 2014, Neuroplasticity and dysfunction after gastrointestinal inflammation, Nat Rev Gastroenterol Hepatol, 11, 611, 10.1038/nrgastro.2014.103 Crosthwaite, 1990, Jejunal circular muscle motility is decreased in nematode-infected rat, Gastroenterology, 98, 59, 10.1016/0016-5085(90)91291-D Hosseini, 1999, Progressive alterations in circular smooth muscle contractility in TNBS-induced colitis in rats, Neurogastroenterol Motil, 11, 347, 10.1046/j.1365-2982.1999.00165.x Bercik, 2004, Visceral hyperalgesia and intestinal dysmotility in a mouse model of postinfective gut dysfunction, Gastroenterology, 127, 179, 10.1053/j.gastro.2004.04.006 Shea-Donohue, 2012, Mechanisms of smooth muscle responses to inflammation, Neurogastroenterol Motil, 24, 802, 10.1111/j.1365-2982.2012.01986.x Coldwell, 2007, Increased responsiveness of rat colonic splanchnic afferents to 5-HT after inflammation and recovery, J Physiol, 579, 203, 10.1113/jphysiol.2006.123158 Zhao, 2008, Th2 cytokine-induced alterations in intestinal smooth muscle function depend on alternatively activated macrophages, Gastroenterology, 135, 217, 10.1053/j.gastro.2008.03.077 Parkman, 2011, Similarities and differences between diabetic and idiopathic gastroparesis, Clin Gastroenterol Hepatol, 9, 1056, 10.1016/j.cgh.2011.08.013 Hasler, 2013, Factors related to abdominal pain in gastroparesis: contrast to patients with predominant nausea and vomiting, Neurogastroenterol Motil, 25, 427, 10.1111/nmo.12091 Parkman, 2010, Gastroparesis and functional dyspepsia: excerpts from the AGA/ANMS meeting, Neurogastroenterol Motil, 22, 113, 10.1111/j.1365-2982.2009.01434.x Ordog, 2000, Remodeling of networks of interstitial cells of Cajal in a murine model of diabetic gastroparesis, Diabetes, 49, 1731, 10.2337/diabetes.49.10.1731 Choi, 2008, Heme oxygenase-1 protects interstitial cells of Cajal from oxidative stress and reverses diabetic gastroparesis, Gastroenterology, 135, 2055, 10.1053/j.gastro.2008.09.003 Neshatian, 2015, Macrophages in diabetic gastroparesis–the missing link?, Neurogastroenterol Motil, 27, 7, 10.1111/nmo.12418 Grover, 2011, Cellular changes in diabetic and idiopathic gastroparesis, Gastroenterology, 140, 1575, 10.1053/j.gastro.2011.01.046 Kashyap, 2010, Carbon monoxide reverses diabetic gastroparesis in NOD mice, Am J Physiol Gastrointest Liver Physiol, 298, G1013, 10.1152/ajpgi.00069.2010 Cipriani, 2016, Diabetic Csf1op/op mice lacking macrophages are protected against the development of delayed gastric emptying, Cell Mol Gastroenterol Hepatol, 2, 40, 10.1016/j.jcmgh.2015.09.001 Choi, 2012, Treatment with IL-10 reverses gastroparesis in diabetic NOD/Shiltj mice, Gastroenterology, 142, S-66, 10.1016/S0016-5085(12)60256-X Asadullah, 2003, Interleukin-10 therapy–review of a new approach, Pharmacol Rev, 55, 241, 10.1124/pr.55.2.4