Determination of Helicobacter pylori CagA EPIYA types in Iranian isolates with different gastroduodenal disorders

Acosta, 2010, Helicobacter pylori CagA protein polymorphisms and their lack of association with pathogenesis, World J. Gastroenterol., 16, 3936, 10.3748/wjg.v16.i31.3936 Atherton, 2006, The pathogenesis of Helicobacter pylori-induced gastro-duodenal diseases, Annu. Rev. Pathol., 1, 63, 10.1146/annurev.pathol.1.110304.100125 Backert, 2010, The versatility of Helicobacter pylori CagA effector protein functions: the master key hypothesis, Helicobacter, 15, 163, 10.1111/j.1523-5378.2010.00759.x Batista, 2011, Higher number of Helicobacter pylori CagA EPIYA C phosphorylation sites increases the risk of gastric cancer, but not duodenal ulcer, BMC Microbiol., 11, 61, 10.1186/1471-2180-11-61 Björkholm, 2001, Mutation frequency and biological cost of antibiotic resistance in Helicobacter pylori, Proc. Natl. Acad. Sci. USA, 98, 14607, 10.1073/pnas.241517298 Chattopadhyay, 2012, Distinct repeat motifs at the C-terminal region of CagA of Helicobacter pylori strains isolated from diseased patients and asymptomatic individuals in West Bengal, India, Gut. Pathog., 4, 4, 10.1186/1757-4749-4-4 Choi, 2007, Analysis of the 3’ variable region of the cagA gene of Helicobacter pylori isolated in Koreans, Dig. Dis. Sci., 52, 960, 10.1007/s10620-005-9030-z Cortes, 2010, Diversity of the cagA gene of Helicobacter pylori strains from patients with gastroduodenal diseases in the Philippines, FEMS Immunol. Med. Microbiol., 60, 90, 10.1111/j.1574-695X.2010.00722.x Dixon, 1996, Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994, Am. J. Surg. Pathol., 20, 1161, 10.1097/00000478-199610000-00001 Duncan, 2012, J-Western forms of Helicobacter pylori cagA constitute a distinct phylogenetic group with a widespread geographic distribution, J. Bacteriol., 194, 1593, 10.1128/JB.06340-11 Furuta, 2011, Evolution of cagA oncogene of Helicobacter pylori through recombination, PLoS ONE, 6, e23499, 10.1371/journal.pone.0023499 Hatakeyama, 2004, Oncogenic mechanisms of the Helicobacter pylori CagA protein, Nat. Rev. Cancer, 4, 688, 10.1038/nrc1433 Hatakeyama, 2005, Helicobacter pylori CagA: a new paradigm for bacterial carcinogenesis, Cancer Sci., 96, 835, 10.1111/j.1349-7006.2005.00130.x Hatakeyama, 2008, SagA of CagA in Helicobacter pylori pathogenesis, Curr. Opin. Microbiol., 11, 30, 10.1016/j.mib.2007.12.003 Hatakeyama, 2009, Helicobacter pylori and gastric carcinogenesis, J. Gastroenterol., 44, 239, 10.1007/s00535-009-0014-1 Hatakeyama, 2011, Anthropological and clinical implications for the structural diversity of the Helicobacter pylori CagA oncoprotein, Cancer Sci., 102, 36, 10.1111/j.1349-7006.2010.01743.x Hayashi, 2012, Bacterial EPIYA effectors – where do they come from? What are they? Where are they going?, Cell. Microbiol. Higashi, 2002, Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites, Proc. Natl. Acad. Sci. USA, 99, 14428, 10.1073/pnas.222375399 Ikenoue, 2001, Determination of Helicobacter pylori virulence by simple gene analysis of the cag pathogenicity island, Clin. Diagn. Lab. Immunol., 8, 181, 10.1128/CDLI.8.1.181-186.2001 Jang, 2010, Epidemiological link between gastric disease and polymorphisms in VacA and CagA, J. Clin. Microbiol., 48, 559, 10.1128/JCM.01501-09 Jones, 2010, A Tale of Two Toxins: Helicobacter pylori CagA and VacA Modulate Host Pathways that Impact Disease, Front. Microbiol., 1, 115, 10.3389/fmicb.2010.00115 Karlsson, 2012, Variation in number of cagA EPIYA-C phosphorylation motifs between cultured Helicobacter pylori and biopsy strain DNA, Infect. Genet. Evol., 12, 175, 10.1016/j.meegid.2011.10.025 Kauser, 2005, Comparing genomes of Helicobacter pylori strains from the high-altitude desert of Ladakh, India, J. Clin. Microbiol., 43, 1538, 10.1128/JCM.43.4.1538-1545.2005 Lu, 2008, Structural and functional diversity in the PAR1b/MARK2-binding region of Helicobacter pylori CagA, Cancer Sci., 99, 2004 Milne, 2009, TOPALi v2: a rich graphical interface for evolutionary analyses of multiple alignments on HPC clusters and multi-core desktops, Bioinformatics, 25, 126, 10.1093/bioinformatics/btn575 Murata-Kamiya, 2011, Pathophysiological functions of the CagA oncoprotein during infection by Helicobacter pylori, Microbes Infect., 13, 799, 10.1016/j.micinf.2011.03.011 Nagase, 2011, Potentiation of Helicobacter pylori CagA protein virulence through homodimerization, J. Biol. Chem., 286, 33622, 10.1074/jbc.M111.258673 Nougayrède, 2005, Cyclomodulins: bacterial effectors that modulate the eukaryotic cell cycle, Trends Microbiol., 13, 103, 10.1016/j.tim.2005.01.002 Ogorodnik, 2012, Analysis of the 3’-variable region of the cagA gene from Helicobacter pylori strains infecting patients at New York city hospitals, Microb. Pathog. Ohnishi, 2008, Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse, Proc. Natl. Acad. Sci. USA, 105, 1003, 10.1073/pnas.0711183105 Olbermann, 2010, A global overview of the genetic and functional diversity in the Helicobacter pylori cag pathogenicity island, PLoS Genet., 6, e1001069, 10.1371/journal.pgen.1001069 Panayotopoulou, 2010, CagA and VacA polymorphisms are associated with distinct pathological features in Helicobacter pylori-infected adults with peptic ulcer and non-peptic ulcer disease, J. Clin. Microbiol., 48, 2237, 10.1128/JCM.00662-10 Polk, 2010, Helicobacter pylori: gastric cancer and beyond, Nat. Rev. Cancer, 10, 403, 10.1038/nrc2857 Ren, 2006, Structural basis and functional consequence of Helicobacter pylori CagA multimerization in cells, J. Biol. Chem., 281, 32344, 10.1074/jbc.M606172200 Russo, 1999, Detection of Helicobacter pylori cagA gene by polymerase chain reaction in faecal samples, Eur. J. Gastroenterol. Hepatol., 11, 251, 10.1097/00042737-199903000-00008 Saberi, 2012, A Potential Association between Helicobacter pylori CagA EPIYA and Multimerization Motifs with Cytokeratin 18 Cleavage Rate during Early Apoptosis, Helicobacter, 17, 350, 10.1111/j.1523-5378.2012.00954.x Salih, 2010, DNA sequence analysis of cagA 3’ motifs of Helicobacter pylori strains from patients with peptic ulcer diseases, J. Med. Microbiol., 59, 144, 10.1099/jmm.0.014894-0 Schmidt, 2009, Distinct cagA EPIYA motifs are associated with ethnic diversity in Malaysia and Singapore, Helicobacter, 14, 256, 10.1111/j.1523-5378.2009.00684.x Secka, 2011, PCR-based genotyping of Helicobacter pylori of Gambian children and adults directly from biopsy specimens and bacterial cultures, Gut Pathog., 3, 5, 10.1186/1757-4749-3-5 Shokrzadeh, 2010, Analysis of 3’-end variable region of the cagA gene in Helicobacter pylori isolated from Iranian population, J. Gastroenterol. Hepatol., 25, 172, 10.1111/j.1440-1746.2009.05979.x Sicinschi, 2010, CagA C-terminal variations in Helicobacter pylori strains from Colombian patients with gastric precancerous lesions, Clin. Microbiol. Infect., 16, 369, 10.1111/j.1469-0691.2009.02811.x Tamura, 2011, MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods, Mol. Biol. Evol., 28, 2731, 10.1093/molbev/msr121 Tao, 2004, A new subtype of 3’ region of cagA gene in Helicobacter pylori strains isolated from Zhejiang Province in China, World J. Gastroenterol., 10, 3284, 10.3748/wjg.v10.i22.3284 Watada, 2011, Association between Helicobacter pylori cagA-related genes and clinical outcomes in Colombia and Japan, BMC Gastroenterol., 11, 141, 10.1186/1471-230X-11-141 Xia, 2009, A comprehensive sequence and disease correlation analyses for the C-terminal region of CagA protein of Helicobacter pylori, PLoS ONE, 4, e7736, 10.1371/journal.pone.0007736 Xu, 2010, Effector prediction in host-pathogen interaction based on a Markov model of a ubiquitous EPIYA motif, BMC Genomics, 11, S1, 10.1186/1471-2164-11-S3-S1