Behçet’s Syndrome

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Diri E, Mat C, Hamuryudan V, et al.: Papulopustular skin lesions are seen more frequently in patients with Behçet’s syndrome who have arthritis: a controlled and masked study. Ann Rheum Dis 2001, 60:1074–1076. Muftuoglu AU, Yurdakul S, Yazici H, et al.: Vascular involvement in Behçet disease: a review of 129 cases. In Recent Advances in Behcet Disease. Edited by Lehner T, Barnes CG. London: Royal Society of Medicine Services; 1986:255–260. Lie JT: Vascular involvement in Behçet’s disease: arterial and venous and vessels of all sizes. J Rheumatol 1992, 19:341–343. Hamuryudan V, Yurdakul S, Moral F, et al.: Pulmonary arterial aneurysms in Behçet’s syndrome: a report of 24 cases. Br J Rheumatol 1994, 33:48–51. Seyahi E, Melikoglu M, Akman C, et al.: Pulmonary vascular involvement in Behçet’s syndrome (BS) [abstract]. Arthritis Rheum 2007, 56(Suppl):853. Seyahi E, Ugurlu S, Cumali R, et al.: Atherosclerosis in Behçet’s syndrome. Semin Arthritis Rheum 2008, 38:1–12. 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Clin Exp Rheumatol 2005, 23(4 Suppl 38):S1–S2. Tunc R, Saip S, Siva A, et al.: Cerebral venous thrombosis is associated with major vessel disease in Behçet’s syndrome. Ann Rheum Dis 2004, 63:1693–1694. Hatemi G, Bahar H, Uysal S, et al.: The pustular skin lesions in Behcet’s syndrome are not sterile. Ann Rheum Dis 2004, 63:1450–1452. Fresko I, Ugurlu S, Ozbakir F, et al.: Anti-Saccharomyces cerevisiae antibodies (ASCA) in Behçet’s syndrome. Clin Exp Rheumatol 2005, 23(4 Suppl 38):S67–S70. Muftuoglu AU, Yazici H, Yurdakul S, et al.: Behçet’s disease. Relation of serum C-reactive protein and erythrocyte sedimentation rates to disease activity. Int J Dermatol 1986, 25:235–239. Criteria for diagnosis of Behçet’s disease. International Study Group for Behçet’s Disease. Lancet 1990, 335:1078–1080. O’Neill TW, Rigby AS, Silman AJ, et al.: Validation of the International Study Group criteria for Behcet’s disease. Br J Rheumatol 1994, 33:115–117. Yazici H, Seyahi E, Yurdakul S: Behçet’s syndrome is not so rare: why do we need to know? Arthritis Rheum 2008, 58:3640–3643. • Kural-Seyahi E, Fresko I, Seyahi N, et al.: The long-term mortality and morbidity of Behçet syndrome: a 2-decade outcome survey of 387 patients followed at a dedicated center. Medicine (Baltimore) 2003, 82:60–76. Aktulga E, Altac M, Muftuoglu A, et al.: A double blind study of colchicine in Behçet’s disease. Haematologica 1980, 65:399–402. Yurdakul S, Mat C, Tuzun Y, et al.: A double-blind trial of colchicine in Behçet’s syndrome. Arthritis Rheum 2001, 44:2686–2692. Yazici H, Pazarli H, Barnes CG, et al.: A controlled trial of azathioprine in Behçet’s syndrome. N Engl J Med 1990, 322:281–285. Hamuryudan V, Ozyazgan Y, Hizli N, et al.: Azathioprine in Behçet’s syndrome: effects on long-term prognosis. Arthritis Rheum 1997, 40:769–774. Masuda K, Nakajima A, Urayama A, et al.: Double-masked trial of cyclosporin versus colchicine and long-term open study of cyclosporin in Behçet’s disease. Lancet 1989, 333:1093–1096. Hamuryudan V, Mat C, Saip S, et al.: Thalidomide in the treatment of the mucocutaneous lesions of the Behçet syndrome. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 1998, 128:443–450. Alpsoy E, Durusoy C, Yilmaz E, et al.: Interferon alfa-2a in the treatment of Behçet disease: a randomized placebo-controlled and double-blind study. Arch Dermatol 2002, 138:467–471. Gueudry J, Wechsler B, Terrada C, et al.: Long-term efficacy and safety of low-dose interferon alpha2a therapy in severe uveitis associated with Behçet disease. Am J Ophthalmol 2008, 146:837.e1–844.e1. Sfikakis PP, Markomichelakis N, Alpsoy E, et al.: Anti-TNF therapy in the management of Behcet’s disease—review and basis for recommendations. Rheumatology (Oxford) 2007, 46:736–741. Melikoglu M, Fresko I, Mat C, et al.: Short-term trial of etanercept in Behçet’s disease: a double blind, placebo controlled study. J Rheumatol 2005, 32:98–105. • Hatemi G, Silman A, Bang D, et al.: EULAR recommendations for the management of Behçet’s disease: report of a task force of the European Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis 2008, 67:1656–1662. This is a very good review of the current information on treatment of BS.