MR Findings of Intrathecal Chemotherapy‐Related Myelopathy in Two Cases: Mimicker of Subacute Combined Degeneration

Journal of Neuroimaging - Tập 17 Số 2 - Trang 184-187 - 2007
C J Lu1,2, Ming Yao1,2, Hon‐Man Liu1,2, Ya‐Fang Chen1,2
1Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan (MY).
2From the Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan (C-HL, H-ML, Y-FC)

Tóm tắt

ABSTRACTWe report the findings of spinal magnetic resonance imaging (MRI) in 2 patients who had undergone intrathecal chemotherapy and presented with the subacute onset of ascending numbness and weakness. MRI revealed a symmetric hyperintensity at the posterior columns of the spinal cord from the lower cervical region down to the conus medullaris level on T2‐weighted images, and no abnormal enhancement. The imaging findings are similar to those seen in subacute combined degeneration (SCD), but the serum vitamin B12 levels were normal in these 2 cases.

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Tài liệu tham khảo

10.1002/1097-0142(19940615)73:12<3037::AID-CNCR2820731223>3.0.CO;2-6

Sherman PM, 2002, Magnetic resonance imaging findings in a case of cytarabine‐induced myelopathy, Mil Med, 167, 157, 10.1093/milmed/167.2.157

10.1200/JCO.1997.15.8.2800

10.1182/blood.V85.8.2025.bloodjournal8582025

10.1111/j.1365-2141.1981.tb07237.x

10.1212/WNL.45.8.1435

10.1002/1097-0142(197712)40:6<2817::AID-CNCR2820400611>3.0.CO;2-V

10.1177/088307380201700312

10.1054/jocn.1998.0149

Pema PJ, 1998, Myelopathy caused by nitrous oxide toxicity, Am J Neuroradiol, 19, 894

Timms SR, 1993, Subacute combined degeneration of the spinal cord: MR findings, Am J Neuroradiol, 14, 1224

10.1001/archneur.1993.00540070055015

Nagaishi A, 2003, A case of subacute combined degeneration with normal serum vitamin B12 level, Rinsho Shinkeigaku., 43, 552

10.1002/1097-0142(19941201)74:11<3034::AID-CNCR2820741122>3.0.CO;2-O

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Thông tin xuất bản

Journal of Neuroimaging

Tập 17 Số 2

184-187

Thông tin tác giả