Immunomodulatory effects of fetal and adult mesenchymal stem cells

Friedenstein, 1968, Heterotopic transplants of bone marrow: analysis of precursor cells for osteogenic and hematopoietic tissue, Transplantation, 6, 230, 10.1097/00007890-196803000-00009 Haynesworth, 1992, Characterization of cells with osteogenic potential from human marrow, Bone, 13, 81, 10.1016/8756-3282(92)90364-3 Prockop, 1997, Marrow stromal cells as stem cells for nonhematopoietic tissues, Science, 276, 71, 10.1126/science.276.5309.71 Pittenger, 1999, Multi-lineage potential of adult human mesenchymal stem cells, Science, 284, 143, 10.1126/science.284.5411.143 Campagnoli, 2001, Identification of mesenchymal stem/progenitor cells in human first- trimester fetal blood, liver, and bone marrow, Blood, 98, 2396, 10.1182/blood.V98.8.2396 Götherström, 2003, Immunomodulatory effects of human foetal liver-derived mesenchymal stem cells, Bone Marrow Transplant, 32, 265, 10.1038/sj.bmt.1704111 Haynesworth, 1992, Cell surface antigens on human marrow-derived mesenchymal cells are detected by monoclonal antibodies, Bone, 13, 69, 10.1016/8756-3282(92)90363-2 Deans, 2000, Mesenchymal stem cells: biology and potential clinical uses, Exp Hematol, 28, 875, 10.1016/S0301-472X(00)00482-3 Majumdar, 1998, Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSC) and stromal cells, J Cell Physiol, 176, 186, 10.1002/(SICI)1097-4652(199807)176:1<57::AID-JCP7>3.0.CO;2-7 Noort, 2002, Mesenchymal stem cells promote engraftment of human umbilical cord bloodderived CD34+ cells in NOD/SCID mice, Exp Hematol, 30, 870, 10.1016/S0301-472X(02)00820-2 Angelopoulou, 2003, Cotransplantation of human mesenchymal stem cells enhances human myelopoesis and megakaryocytopoiesis in NOD/SCID mice, Exp Hematol, 31, 413, 10.1016/S0301-472X(03)00042-0 Pereira, 1995, Cultured adherent cells from marrow can serve as long-lasting precursors for bone, cartilage, and lung in irradiated mice, Proc Natl Acad Sci USA, 92, 4857, 10.1073/pnas.92.11.4857 Liechty, 2000, Human mesenchymal stem cells engraft and demonstrate site- specific differentiation after in utero transplantation in sheep, Nat Med, 6, 1282, 10.1038/81395 Devine, 2003, Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into non-human primates, Blood, 101, 2999, 10.1182/blood-2002-06-1830 Tse, 2003, Suppression of allogeneic T-cell proliferation by human marrow stromal cells: Implications in transplantation, Transplantation, 75, 389, 10.1097/01.TP.0000045055.63901.A9 Majumdar, 2003, Characterization and functionality of cell surface molecules on human mesencymal stem cells, J Biomed Sci, 10, 228, 10.1007/BF02256058 Le Blanc K, Tammik L, Zetterberg E, Rosendahl K, Ringdén O. HLA-expression and immunologic properties of undifferentiated and differentiated mesenchymal stem cells. Exp Hematol In press. Götherström, 2003, Immunological properties of human fetal mesenchymal stem cells, Am J Obst Gynecol, 31, 890 McIntosh, 2000, Stromal cell modulation of the immune system, Graft, 3, 324 Di Nicola, 2002, Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or non-specific mitogenic stimuli, Blood, 99, 3838, 10.1182/blood.V99.10.3838 Krampera, 2003, Bone marrow mesenchymal stem cells inhibit the response of naive antigen specific T-cells to their cognate peptide, Blood, 101, 3722, 10.1182/blood-2002-07-2104 Wilson, 1995, Renal allograft rejection, Tubular epithelial cells present alloantigen in the presence of costimulatory CD28 antibody. Transplantation, 59, 91 Laning, 2001, In vitro analysis of CD40- CD154 and CD28-CD80/86 interactions in the prmary T-cell response to allogeneic ‘nonprofessional’ antigen presenting cells, Transplantation, 71, 1467, 10.1097/00007890-200105270-00019 Bartholomew, 2001, Baboon mesenchymal stem cells can be genetically modified to secrete human erythropoietin in vivo, Hum Gene Therapy, 12, 1527, 10.1089/10430340152480258 Devine, 2001, Mesenchymal stem cells are capable of homing to the bone marrow of nonhuman primates following systemic infusion, Exp Hematol, 29, 244, 10.1016/S0301-472X(00)00635-4 Gurevitch, 1999, Transplantation of allogeneic or xenogenic bone marrow within the donor stromal microenvironment, Transplantation, 68, 1362, 10.1097/00007890-199911150-00024 Bingaman, 2000, Transplantation of the bone marrow microenvironment leads to hematopoietic chimerism without cytoreductive conditioning, Transplantation, 69, 2491, 10.1097/00007890-200006270-00006 Yin, 2000, Allograft tolerance induced by intact active bone cotransplantation and anti-CD40L monoclonal antibody therapy, Transplantation, 74, 345, 10.1097/00007890-200208150-00009 Bartholomew, 2002, Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo, Exp Hematol, 30, 42, 10.1016/S0301-472X(01)00769-X Le Blanc, 2003, Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex, Scand J Immunol, 57, 11, 10.1046/j.1365-3083.2003.01176.x Frassoni, 2002, Expanded mesenchymal stem cells (MSC), co-infused with HLA identical hematopoietic stem cell transplants, reduce acute and chronic graftversus- host disease: a matched pair analysis, Bone Marrow Transplant, 29, S2 Rasmusson, 2003, Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes (CTL), but not activated CTL or natural killer (NK) cells, Transplantation, 76, 1208, 10.1097/01.TP.0000082540.43730.80