Clinicopathologic significance of DNA mismatch repair protein defects and endometrial cancer in women 40years of age and younger

Lu, 2005, Gynecologic cancer as a “sentinel cancer” for women with hereditary nonpolyposis colorectal cancer syndrome, Obstet Gynecol, 105, 569, 10.1097/01.AOG.0000154885.44002.ae Black, 2006, Clinicopathologic significance of defective DNA mismatch repair in endometrial carcinoma, J Clin Oncol, 24, 1745, 10.1200/JCO.2005.04.1574 Zighelboim, 2007, Microsatellite instability and epigenetic inactivation of MLH1 and outcome of patients with endometrial carcinomas of the endometrioid type, J Clin Oncol, 25, 2042, 10.1200/JCO.2006.08.2107 Westin, 2008, Carcinoma of the lower uterine segment: a newly described association with Lynch syndrome, J Clin Oncol, 26, 5965, 10.1200/JCO.2008.18.6296 Garg, 2009, Lynch syndrome (hereditary non-polyposis colorectal cancer) and endometrial carcinoma, J Clin Pathol, 62, 679, 10.1136/jcp.2009.064949 Hampel, 2006, Screening for Lynch syndrome (hereditary nonpolyposis colorectal cancer) among endometrial cancer patients, Cancer Res, 66, 7810, 10.1158/0008-5472.CAN-06-1114 Berends, 2003, Toward new strategies to select young endometrial cancer patients for mismatch repair gene mutation analysis, J Clin Oncol, 21, 4364, 10.1200/JCO.2003.04.094 Broaddus, 2006, Pathologic features of endometrial carcinoma associated with HNPCC: a comparison with sporadic endometrial carcinoma, Cancer, 106, 87, 10.1002/cncr.21560 Planck, 2002, High frequency of microsatellite instability and loss of mismatch-repair protein expression in patients with double primary tumors of the endometrium and colorectum, Cancer, 94, 2502, 10.1002/cncr.10501 Soliman, 2005, Women with synchronous primary cancers of the endometrium and ovary: do they have Lynch syndrome?, J Clin Oncol, 23, 9344, 10.1200/JCO.2005.03.5915 Walsh, 2010, Lynch syndrome among gynecologic oncology patients meeting Bethesda guidelines for screening, Gynecol Oncol, 116, 516, 10.1016/j.ygyno.2009.11.021 Walsh, 2008, Molecular, pathologic, and clinical features of early-onset endometrial cancer: identifying presumptive Lynch syndrome patients, Clin Cancer Res, 14, 1692, 10.1158/1078-0432.CCR-07-1849 Manders, 2011, Young age and a positive family history of colorectal cancer are complementary selection criteria for the identification of Lynch syndrome, Eur J Cancer, 47, 1407, 10.1016/j.ejca.2010.12.024 Hampel, 2005, Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer), N Engl J Med, 352, 1851, 10.1056/NEJMoa043146 Pinol, 2005, Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer, JAMA, 293, 1986, 10.1001/jama.293.16.1986 Resnick, 2009, Current and emerging trends in Lynch syndrome identification in women with endometrial cancer, Gynecol Oncol, 114, 128, 10.1016/j.ygyno.2009.03.003 Lancaster, 2007, Society of Gynecologic Oncologists Education Committee statement on risk assessment for inherited gynecologic cancer predispositions, Gynecol Oncol, 107, 159, 10.1016/j.ygyno.2007.09.031 Evans-Metcalf, 1998, Profile of women 45years of age and younger with endometrial cancer, Obstet Gynecol, 91, 349, 10.1016/S0029-7844(97)00668-6 Soliman, 2005, Risk factors for young premenopausal women with endometrial cancer, Obstet Gynecol, 105, 575, 10.1097/01.AOG.0000154151.14516.f7 Schmeler, 2005, Endometrial cancer in young, normal-weight women, Gynecol Oncol, 99, 388, 10.1016/j.ygyno.2005.06.029 Uharcek, 2008, Prognostic factors in women 45years of age or younger with endometrial cancer, Int J Gynecol Cancer, 18, 324, 10.1111/j.1525-1438.2007.00997.x Navarria, 2009, Young patients with endometrial cancer: how many could be eligible for fertility-sparing treatment?, Gynecol Oncol, 114, 448, 10.1016/j.ygyno.2009.05.038 Ota, 2005, Clinicopathologic study of uterine endometrial carcinoma in young women aged 40years and younger, Int J Gynecol Cancer, 15, 657, 10.1111/j.1525-1438.2005.00129.x Ushijima, 2007, Multicenter phase II study of fertility-sparing treatment with medroxyprogesterone acetate for endometrial carcinoma and atypical hyperplasia in young women, J Clin Oncol, 25, 2798, 10.1200/JCO.2006.08.8344 Wang, 2002, Fertility-preserving treatment in young patients with endometrial adenocarcinoma, Cancer, 94, 2192, 10.1002/cncr.10435 Järvinen, 2009, Ten years after mutation testing for Lynch syndrome: cancer incidence and outcome in mutation-positive and mutation-negative family members, J Clin Oncol, 27, 4793, 10.1200/JCO.2009.23.7784 Garg, 2009, Endometrial carcinomas in women aged 40years and younger: tumors associated with loss of DNA mismatch repair proteins comprise a distinct clinicopathologic subset, Am J Surg Pathol, 33, 1869, 10.1097/PAS.0b013e3181bc9866 Benedet, 2000, FIGO staging classifications and clinical practice guidelines in the management of gynecologic cancers. FIGO Committee on Gynecologic Oncology, Int J Gynaecol Obstet, 70, 209, 10.1016/S0020-7292(00)90001-8 Vasen, 1999, New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC, Gastroenterology, 116, 1453, 10.1016/S0016-5085(99)70510-X Umar, 2004, Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability, J Natl Cancer Inst, 96, 261, 10.1093/jnci/djh034 Kauff, 2007, How should women with early-onset endometrial cancer be evaluated for lynch syndrome?, J Clin Oncol, 25, 5143, 10.1200/JCO.2007.13.4940 Lynch, 2009, Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications, Clin Genet, 76, 1, 10.1111/j.1399-0004.2009.01230.x Matthews, 2008, Lynch syndrome in women less than 50years of age with endometrial cancer, Obstet Gynecol, 111, 1161, 10.1097/AOG.0b013e31817051d9 Lu, 2007, Prospective determination of prevalence of lynch syndrome in young women with endometrial cancer, J Clin Oncol, 25, 5158, 10.1200/JCO.2007.10.8597 Cohn, 2006, Improved survival with an intact DNA mismatch repair system in endometrial cancer, Obstet Gynecol, 108, 1208, 10.1097/01.AOG.0000239097.42987.0c Backes, 2009, Prospective evaluation of DNA mismatch repair protein expression in primary endometrial cancer, Gynecol Oncol, 114, 486, 10.1016/j.ygyno.2009.05.026