Receptor-mediated toxicity

Toxicology Letters - Tập 82 - Trang 465-470 - 1995
Jan-Åke Gustafsson1
1Karolinska Institutet, Department of Medical Nutrition, Novum, S-141 86 Huddinge, Sweden

Tài liệu tham khảo

Härd, 1990, Solution structure of the glucocorticoid receptor DNA-binding domain, Science, 249, 157, 10.1126/science.2115209 Bourguet, 1995, Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α, Nature, 375, 377, 10.1038/375377a0 Baxter, 1995, 36 Dahlman-Wright, 1994, Delineation of a small region within the major transactivation domain of the human glucocorticoid receptor that mediates transactivation of gene expression, 91, 1619 Almlöf, T., Gustafsson, J.-Å. and Wright A.P.H. In preparation. Dahlman-Wright, 1995, Structural characterization of a minimal functional transactivation domain from the human glucocorticoid receptor, 92, 1699 Caldenhoven, 1995, Negative cross-talk between Rel A and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids, Mol. Endocrinol., 9, 401, 10.1210/me.9.4.401 Issemann, 1990, Activation of a member of the steroid hormone receptor superfamily by peroxi-some proliferators, Nature, 347, 645, 10.1038/347645a0 Göttlicher, 1992, Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor, 89, 4653 Albrektsen, L., Schrøder, T., Göttlicher, M., Elholm, M., Gustafsson, J.-Å., Kristiansen, K. and Knudsen, J. Ligand binding of the peroxisome proliferator activated receptor studied by photoaffinity labelling. Submitted for publication. Göttlicher, 1993, Structural and metabolic requirements for activators of the peroxisome proliferator activated receptor, Biochem. Pharmacol., 46, 2177, 10.1016/0006-2952(93)90607-X Treuter, E. and Gustafsson, J.-Å. Manuscript in preparation. Corton, C, Bocos C. and Gustafsson J.-Å. Manuscript in preparation. Whitelaw, 1993, Definition of a novel ligand binding domain of a nuclear bHLH receptor, co-localization of ligand and hsp90 binding activities within the regulable inactivation domain of the dioxin receptor, EMBO J, 12, 4169, 10.1002/j.1460-2075.1993.tb06101.x Whitelaw, 1995, Heat shock protein hsp90 regulates dioxin receptor function in vivo, 92, 4437 Kleman, 1992, In vitro activation of the dioxin receptor to a DNA-binding form by food-borne heterocyclic amines, Carcinogenesis, 13, 1619, 10.1093/carcin/13.9.1619 Kleman, M., Poellinger, L. and Gustafsson, J.-Å. Manuscript in preparation. Wattenberg, 1980, Inhibitors of chemical carcinogens, Vol. 7, 517 Gillner, 1985, Interactions of indoles with specific binding sites for if2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver, Mol. Pharmacol., 28, 357 Gillner, 1993, Interactions of indolo[3,2b]carbazoles and related polycyclic aromatic hydrocarbons with specific binding sites for 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver, Mol. Pharmacol., 44, 336 Kleman, 1994, Regulation of human dioxin receptor function by indolocarbazoles, receptor ligands of dietary origin, J. Biol. Chem., 269, 5137, 10.1016/S0021-9258(17)37666-4 Huikko, M.-P. and Gustafsson, J.-Å. Manuscript in preparation. Nordlund-Möller, 1990, Cloning, structure, and expression of a rat binding protein for polychlorinated biphenyls, J. Biol. Chem., 265, 12690, 10.1016/S0021-9258(19)38399-1 Härd, 1995, Solution structure of a mammalian PCB-binding protein in complex with a PCB, Nature Struct. Biol., 2, 983, 10.1038/nsb1195-983