Chitosan as a starting material for wound healing applications

Barrientos, 2008, Growth factors and cytokines in wound healing, Wound Repair Regen., 16, 585, 10.1111/j.1524-475X.2008.00410.x Dreifke, 2015, Current wound healing procedures and potential care, Mater. Sci. Eng. C, 48, 651, 10.1016/j.msec.2014.12.068 Hynes, 2009, The extracellular matrix: not just pretty fibrils, Science, 326, 1216, 10.1126/science.1176009 Folkman, 2007, Angiogenesis: an organizing principle for drug discovery?, Nat. Rev. Drug. Discov., 6, 273, 10.1038/nrd2115 Glim, 2014, Extracellular matrix components of oral mucosa differ from skin and resemble that of foetal skin, Arch. Oral Biol., 59, 1048, 10.1016/j.archoralbio.2014.05.019 Boateng, 2008, Wound healing dressings and drug delivery systems: a review, J. Pharm. Sci., 97, 2892, 10.1002/jps.21210 U. Kyriacos, R. de Swardt, F. Mtshali, T. Khanyile, J. van Heerden, S. Duma, L. Maree, T. Puoane, Fresh perspectives: fundamentals of nursing, in: I. Parsons (Ed.), Pearson South, Africa, 2008, pp. 167–190. Ninan, 2014, Wound healing analysis of pectin/carboxymethyl cellulose/microfibrillated cellulose based composite scaffolds, Mater. Lett., 132, 34, 10.1016/j.matlet.2014.06.056 Muzzarelli, 2009, Chitins and chitosans for the repair of wounded skin, nerve, cartilage and bone, Carbohydr. Polym., 76, 167, 10.1016/j.carbpol.2008.11.002 Ulubayram, 2001, EGF containing gelatin-based wound dressings, Biomaterials, 22, 1345, 10.1016/S0142-9612(00)00287-8 Bui, 2014, Fabrication and characterization of electrospun curcumin-loaded polycaprolactone-polyethylene glycol nanofibers for enhanced wound healing, Macromol. Res., 22, 1288, 10.1007/s13233-014-2179-6 Estes, 1993, Hyaluronate metabolism undergoes and ontogenic transition during fetal development: Implications for Scar-free wound healing, J. Pediat. Surg., 28, 1227, 10.1016/S0022-3468(05)80303-3 Baldrick, 2010, The safety of chitosan as a pharmaceutical excipient, Regul. Toxicol. Pharmacol., 56, 290, 10.1016/j.yrtph.2009.09.015 Muzzarelli, 1999, Biochemistry, histology and clinical uses of chitins and chitosans in wound healing, EXS, 87, 251 Yilmaz, 2004, Chitosan: a versatile biomaterial, Adv. Exp. Med. Biol., 553, 59, 10.1007/978-0-306-48584-8_5 Senel, 2004, Potential applications of chitosan in veterinary medicine, Adv. Drug Deliv. Rev., 56, 1467, 10.1016/j.addr.2004.02.007 Berger, 2005, Pseudo-thermosetting chitosan hydrogels for biomedical application, Int. J. Pharm., 288, 197, 10.1016/j.ijpharm.2004.07.037 Florea, 2006, Enhancement of bronchial octreotide absorption by chitosan and N-trimethyl chitosan shows linear in vitro/in vivo correlation, J. Control. Release, 110, 353, 10.1016/j.jconrel.2005.10.001 Delgadillo-Armendariz, 2014, Interactions of chitosan/genipin hydrogels during drug delivery: a QSPR approach, Quím. Nova, 37, 1503 Chemical Carcinogenesis Research Information System,(CCRIS), <http://toxnet.nlm.nih.gov> (accessed 26.11.14). Alves, 2008, Chitosan derivatives obtained by chemical modifications for biomedical and environmental applications, Int. J. Biol. Macromol., 43, 401, 10.1016/j.ijbiomac.2008.09.007 Berger, 2004, Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications, Eur. J. Pharm. Biopharm., 57, 19, 10.1016/S0939-6411(03)00161-9 Patois, 2009, Novel thermosensitive chitosan hydrogels: in vivo evaluation, J. Biomed. Mater. Res. A, 91, 324, 10.1002/jbm.a.32211 Schuetz, 2008, A novel thermoresponsive hydrogel based on chitosan, Eur. J. Pharm. Biopharm., 68, 19, 10.1016/j.ejpb.2007.06.020 Thanou, 2002, Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell lines, Biomaterials, 23, 153, 10.1016/S0142-9612(01)00090-4 Hansson, 2012, Preparation and evaluation of nanoparticles for directed tissue engineering, Int. J. Pharm., 439, 73, 10.1016/j.ijpharm.2012.09.053 Janvikul, 2006, In vitro comparative hemostatic studies of chitin, chitosan, and their derivatives, J. Appl. Polym. Sci., 102, 445, 10.1002/app.24192 Chen, 2006, Development of N, O-(carboxymethyl)chitosan/collagen matrixes as a wound dressing, Biomacromolecules, 7, 1058, 10.1021/bm050754b Casettari, 2012, PEGylated chitosan derivatives: Synthesis, characterizations and pharmaceutical applications, Prog. Polym. Sci., 37, 659, 10.1016/j.progpolymsci.2011.10.001 Park, 2010, Targeted delivery of low molecular drugs using chitosan and its derivatives, Adv. Drug Deliv. Rev., 62, 28, 10.1016/j.addr.2009.10.003 Francesko, 2011, Chitin, chitosan and derivatives for wound healing and tissue engineering, Adv. Biochem. Eng. Biotechnol., 125, 1 Moura, 2013, Recent advances on the development of wound dressings for diabetic foot ulcer treatment – a review, Acta Biomater., 9, 7093, 10.1016/j.actbio.2013.03.033 Moura, 2014, Chitosan-based dressings loaded with neurotensin – an efficient strategy to improve early diabetic wound healing, Acta Biomater., 10, 843, 10.1016/j.actbio.2013.09.040 Dodane, 1998, Pharmaceutical applications of chitosan, Pharm. Sci. Technol. Today, 1, 246, 10.1016/S1461-5347(98)00059-5 Irvine, 1912, CXIX. – the conversion of d-Glucosamine into d-Glucose, J. Chem. Soc. Trans., 101, 1128, 10.1039/CT9120101128 Prudden, 1970, The discovery of a potent pure chemical wound-healing accelerator, Am. J. Surg., 119, 560, 10.1016/0002-9610(70)90175-3 Kifune, 1992, Clinical application of chitin artificial skin (Beschitin W), 9 Okamoto, 1993, Application of polymeric N-acetyl-d-glucosamine (Chitin) to veterinary practice, J. Vet. Med. Sci., 55, 743, 10.1292/jvms.55.743 Azad, 2004, Chitosan membrane as a wound-healing dressing: characterization and clinical application, J. Biomed. Mater. Res. Part B Appl. Biomater., 69B, 10.1002/jbm.b.30000 Schipper, 1997, Chitosans as absorption enhancers for poorly absorbable drugs 2: mechanism of absorption enhancement, Pharm. Res., 14, 923, 10.1023/A:1012160102740 Wimardani, 2012, Cytotoxic effects of chitosan against oral cancer cell lines is molecular-weight-dependent and cell-type-specific, Int. J. Oral Res., 3, 1 Wimardhani, 2014, Chitosan exerts anticancer activity through induction of apoptosis and cell cycle arrest in oral cancer cells, J. Oral Sci., 56, 119, 10.2334/josnusd.56.119 Carreño-Gómez, 1997, Evaluation of the biological properties of soluble chitosan and chitosan microspheres, Int. J. Pharm., 148, 231, 10.1016/S0378-5173(96)04847-8 Ribeiro, 2009, Development of a new chitosan hydrogel for wound dressing, Wound Repair Regen., 17, 817, 10.1111/j.1524-475X.2009.00538.x Arai, 1968, Toxicity of chitosan, Bull. Tokai Reg. Fish. Res. Lab., 56, 89 Costa, 2014, Chitosan mouthwash: toxicity and in vivo validation, Carbohydr. Polym., 111, 385, 10.1016/j.carbpol.2014.04.046 Rao, 1997, Use of chitosan as a biomaterial: studies on its safety and hemostatic potential, J. Biomed. Mater. Res., 34, 21, 10.1002/(SICI)1097-4636(199701)34:1<21::AID-JBM4>3.0.CO;2-P Porporatto, 2005, Local and systemic activity of the polysaccharide chitosan at lymphoid tissues after oral administration, J. Leukocyte Biol., 78, 62, 10.1189/jlb.0904541 Ueno, 2001, Topical formulations and wound healing applications of chitosan, Adv. Drug Deliv. Rev., 52, 105, 10.1016/S0169-409X(01)00189-2 Gades, 2003, Chitosan supplementation and fecal fat excretion in men, Obes. Res., 11, 683, 10.1038/oby.2003.97 Ylitalo, 2002, Cholesterol-lowering properties and safety of chitosan, Arzneimittelforschung, 52, 1 Agnihotri, 2004, Recent advances on chitosan-based micro- and nanoparticles in drug delivery, J. Control. Release, 100, 5, 10.1016/j.jconrel.2004.08.010 Felt, 2000, Chitosan as tear substitute: a wetting agent endowed with antimicrobial efficacy, J. Ocul. Pharmacol. Ther., 16, 261, 10.1089/jop.2000.16.261 Yan, 2010, Biocompatibility evaluation of chitosan-based injectable hydrogels for the culturing mice mesenchymal stem cells in vitro, J. Biomater. Appl., 24, 625, 10.1177/0885328208100536 Mizuno, 2003, Effect of chitosan film containing basic fibroblast growth factor on wound healing in genetically diabetic mice, J. Biomed. Mater. Res. Part A, 64A, 177, 10.1002/jbm.a.10396 Ishihara, 2001, Acceleration of wound contraction and healing with a photocrosslinkable chitosan hydrogel, Wound Repair Regen., 9, 513, 10.1046/j.1524-475x.2001.00513.x Shigemasa, 1996, Applications of chitin and chitosan for biomaterials, Biotechnol. Genet. Eng., 13, 383, 10.1080/02648725.1996.10647935 Ueno, 1999, Accelerating effects of chitosan for healing at early phase of experimental open wound in dogs, Biomaterials, 20, 1407, 10.1016/S0142-9612(99)00046-0 Howling, 2001, The effect of chitin and chitosan on the proliferation of human skin fibroblasts and keratinocytes in vitro, Biomaterials, 22, 2959, 10.1016/S0142-9612(01)00042-4 Simard, 2009, Neutrophils exhibit distinct phenotypes toward chitosans with different degrees of deacetylation: implications for cartilage repair, Arthritis Res. Ther., 11, 1, 10.1186/ar2703 Park, 2009, Accelerated wound closure of pressure ulcers in aged mice by chitosan scaffolds with and without bFGF, Acta Biomater., 5, 1926, 10.1016/j.actbio.2009.03.002 Baxter, 2013, Chitosan dressing promotes healing in third degree burns in mice. gene expression analysis shows biphasic effects for rapid tissue regeneration and decreased fibrotic signaling, J. Biomed. Mater. Res. A, 101, 340, 10.1002/jbm.a.34328 Luca, 2011, Injectable rhBMP-2-loaded chitosan hydrogel composite: osteoinduction at ectopic site and in segmental long bone defect, J. Biomed. Mater. Res. A, 96, 66, 10.1002/jbm.a.32957 Alemdaroğlu, 2006, An investigation on burn wound healing in rats with chitosan gel formulation containing epidermal growth factor, Burns, 32, 319, 10.1016/j.burns.2005.10.015 Obara, 2005, Acceleration of wound healing in healing-impaired db/db mice with a photocrosslinkable chitosan hydrogel containing fibroblast growth factor-2, Wound Repair Regen., 13, 390, 10.1111/j.1067-1927.2005.130406.x Gopal, 2014, Chitosan-based copper nanocomposite accelerates healing in excision wound model in rats, Eur. J. Pharm., 731, 8, 10.1016/j.ejphar.2014.02.033 Judith, 2010, Application of a PDGF-containing novel gel for cutaneous wound healing, Life Sci., 87, 1, 10.1016/j.lfs.2010.05.003 Frank, 1995, Regulation of vascular endothelial growth factor expression in cultured keratinocytes. Implications for normal and impaired wound healing, J. Biol. Chem., 270, 12607, 10.1074/jbc.270.21.12607 Obara, 2003, Photocrosslinkable chitosan hydrogel containing fibroblast growth factor-2 stimulates wound healing in healing-impaired db/db mice, Biomaterials, 24, 3437, 10.1016/S0142-9612(03)00220-5 Rossi, 2013, “Sponge-like” dressings based on biopolymers for the delivery of platelet lysate to skin chronic wounds, Int. J. Pharm., 440, 207, 10.1016/j.ijpharm.2012.07.056 Dai, 2009, Chitosan acetate bandage as a topical antimicrobial dressing for infected burns, Antimicrob. Agents Chemother., 53, 393, 10.1128/AAC.00760-08 Noel, 2010, Chitosan sponges to locally deliver amikacin and vancomycin: a pilot in vitro evaluation, Clin. Orthop. Relat. Res., 468, 2074, 10.1007/s11999-010-1324-6 Jin, 2007, Effects of chitosan and heparin on early extension of burns, Burns, 33, 1027, 10.1016/j.burns.2006.12.002 Kratz, 1997, Heparin-chitosan complexes stimulate wound healing in human skin, Scand. J. Plast. Reconstr. Surg. Hand. Surg., 31, 119, 10.3109/02844319709085478 Chupa, 2000, Vascular cell responses to polysaccharide materials: in vitro and in vivo evaluations, Biomaterials, 21, 2315, 10.1016/S0142-9612(00)00158-7 Stone, 2000, Healing at skin graft donor sites dressed with chitosan, Brit. J. Plast. Surg., 53, 601, 10.1054/bjps.2000.3412 Ho, 2001, A prospective controlled clinical study of skin donor sites treated with a 1-4,2-acetamide-deoxy-B-d-glucan polymer: a preliminary report, Burns, 27, 759, 10.1016/S0305-4179(01)00050-X Kratz, 1998, Immobilised heparin accelerates the healing of human wounds in vivo, Scand. J. Plast. Reconstr. Surg. Hand. Surg., 32, 381, 10.1080/02844319850158462 Vescovali, 1989, Epidermalization of an artificial dermis made of collagen, Annals oj’the MBC, 2, 137 Damour, 1994, A dermal substrate made of collagen-GAG-chitosan for deep burn coverage: first clinical uses, Clin. Mater., 15, 273, 10.1016/0267-6605(94)90057-4 Chatelet, 2001, Influence of the degree of acetylation on some biological properties of chitosan films, Biomaterials, 22, 261, 10.1016/S0142-9612(00)00183-6 Ishihara, 2002, Photocrosslinkable chitosan as a dressing for wound occlusion and accelerator in healing process, Biomaterials, 23, 833, 10.1016/S0142-9612(01)00189-2 Boucard, 2007, The use of physical hydrogels of chitosan for skin regeneration following third-degree burns, Biomaterials, 28, 3478, 10.1016/j.biomaterials.2007.04.021 Boucard, 2005, New aspects of the formation of physical hydrogels of chitosan in a hydroalcoholic medium, Biomacromolecules, 6, 3227, 10.1021/bm050653d Hoemann, 2005, Tissue engineering of cartilage using an injectable and adhesive chitosan-based cell-delivery vehicle, Osteoarthr. Cartilage, 13, 318, 10.1016/j.joca.2004.12.001 Minami, 1999, Veterinary practice with chitin and chitosan, 265 Kean, 2010, Biodegradation, biodistribution and toxicity of chitosan, Adv. Drug Deliv. Rev., 62, 3, 10.1016/j.addr.2009.09.004 Sieval, 1998, Preparation and NMR characterization of highly substituted N-trimethyl chitosan chloride, Carbohydr. Polym., 36, 157, 10.1016/S0144-8617(98)00009-5 Muzzarelli, 2002, N-Carboxymethyl chitosan in innovative cosmeceutical products, J. Appl. Cosmetol., 20, 201 Borchard, 2001, Chitosans for gene delivery, Adv. Drug Deliv. Rev., 52, 145, 10.1016/S0169-409X(01)00198-3 de Britto, 2007, A novel method for obtaining a quaternary salt of chitosan, Carbohydr. Polym., 69, 305, 10.1016/j.carbpol.2006.10.007 Wolfrom, 1964, Methylation studies on carboxyl-reduced heparin. 2-Amino-2-deoxy-3,6-di-O-methyl-α-d-glucopyranose from the methylation of chitosan, J. Org. Chem., 29, 547, 10.1021/jo01026a006 Nud’ga, 1975, Cyanoethylation of chitosan, Zh. Obshch. Khim., 45, 1145 Muzzarelli, 1985, The N-permethylation of chitosan and the preparation of N-trimethyl chitosan iodide, Carbohydr. Polym., 5, 297, 10.1016/0144-8617(85)90037-2 Domard, 1986, New method for the quaternization of chitosan, Int. J. Biol. Macromol., 8, 105, 10.1016/0141-8130(86)90007-3 Verheul, 2008, Synthesis, characterization and in vitro biological properties of O-methyl free N, N,N-trimethylated chitosan, Biomaterials, 29, 3642, 10.1016/j.biomaterials.2008.05.026 Patrulea, 2015, Optimized synthesis of O-carboxymethyl-N,N,N-trimethyl chitosan, Carbohydr. Polym., 122, 46, 10.1016/j.carbpol.2014.12.014 Murata, 1996, Possibility of application of quaternary chitosan having pendant galactose residues as gene delivery tool, Carbohydr. Polym., 29, 69, 10.1016/0144-8617(95)00144-1 Kean, 2005, Trimethylated chitosans as non-viral gene delivery vectors: cytotoxicity and transfection efficiency, J. Control. Release, 103, 643, 10.1016/j.jconrel.2005.01.001 Mao, 2005, Synthesis, characterization and cytotoxicity of poly(ethylene glycol)-graft-trimethyl chitosan block copolymers, Biomaterials, 26, 6343, 10.1016/j.biomaterials.2005.03.036 Guo, 2011, The healing of full-thickness burns treated by using plasmid DNA encoding VEGF-165 activated collagen–chitosan dermal equivalents, Biomaterials, 32, 1019, 10.1016/j.biomaterials.2010.08.087 Guo, 2010, Enhanced angiogenesis of gene-activated dermal equivalent for treatment of full thickness incisional wounds in a porcine model, Biomaterials, 31, 7308, 10.1016/j.biomaterials.2010.06.013 Pang, 2007, Preparation and rheological properties of deoxycholate-chitosan and carboxymethyl-chitosan in aqueous systems, Carbohydr. Polym., 69, 419, 10.1016/j.carbpol.2006.12.026 Chung, 1994, Biocompatibility of potential wound management products: fungal mycelia as a source of chitin/chitosan and their effect on the proliferation of human F1000 fibroblasts in culture, J. Biomed. Mater. Res., 28, 463, 10.1002/jbm.820280409 Fei Liu, 2001, Antibacterial action of chitosan and carboxymethylated chitosan, J. Appl. Polym. Sci., 79, 1324, 10.1002/1097-4628(20010214)79:7<1324::AID-APP210>3.0.CO;2-L Chen, 2002, The effect of carboxymethyl-chitosan on proliferation and collagen secretion of normal and keloid skin fibroblasts, Biomaterials, 23, 4609, 10.1016/S0142-9612(02)00207-7 Hansson, 2012, In vitro evaluation of an RGD-functionalized chitosan derivative for enhanced cell adhesion, Carbohydr. Polym., 90, 1494, 10.1016/j.carbpol.2012.07.020 Zheng, 2011, Synthesis, characterization and biological safety of O-carboxymethyl chitosan used to treat Sarcoma 180 tumor, Carbohydr. Polym., 86, 231, 10.1016/j.carbpol.2011.04.038 Yang, 2012, Acute toxicity of high dosage carboxymethyl chitosan and its effect on the blood parameters in rats, J. Mater. Sci. – Mater. Med., 23, 457, 10.1007/s10856-011-4467-4 Abdull Rasad, 2010, In vitro evaluation of novel chitosan derivatives sheet and paste cytocompatibility on human dermal fibroblasts, Carbohydr. Polym., 79, 1094, 10.1016/j.carbpol.2009.10.048 Lim, 2007, In vitro cytotoxicology model of oligo-chitosan and n, o-carboxymethyl chitosan using primary normal human epidermal keratinocyte cultures, J. Appl. Biomater. Biomech., 5, 82 Huang, 2013, Influence of radiation crosslinked carboxymethyl-chitosan/gelatin hydrogel on cutaneous wound healing, Mater. Sci. Eng. C, 33, 4816, 10.1016/j.msec.2013.07.044 Masuko, 2005, Chitosan-RGDSGGC conjugate as a scaffold material for musculoskeletal tissue engineering, Biomaterials, 26, 5339, 10.1016/j.biomaterials.2005.01.062 Chung, 2007, Surface engineered and drug releasing pre-fabricated scaffolds for tissue engineering, Adv. Drug Deliv. Rev., 59, 249, 10.1016/j.addr.2007.03.015 Johansson, 1989, A peptide containing the cell adhesion sequence RGD can mediate degranulation and cell adhesion of crayfish granular haemocytes in vitro, Insect Biochem., 19, 573, 10.1016/0020-1790(89)90022-X Ho, 2005, Preparation and characterization of RGD-immobilized chitosan scaffolds, Biomaterials, 26, 3197, 10.1016/j.biomaterials.2004.08.032 Massia, 1990, Covalent surface immobilization of Arg-Gly-Asp- and Tyr-Ile-Gly-Ser-Arg-containing peptides to obtain well-defined cell-adhesive substrates, Anal. Biochem., 187, 292, 10.1016/0003-2697(90)90459-M Karakecili, 2007, Evaluation of L929 fibroblast attachment and proliferation on Arg-Gly-Asp-Ser (RGDS)-immobilized chitosan in serum-containing/serum-free cultures, J. Biosci. Bioeng., 104, 69, 10.1263/jbb.104.69 Jansma, 2003, Preparation and characterization of 6-O-carboxymethyl-N-trimethyl chitosan derivative as a potential carrier for targeted polymeric gene and drug delivery, STP Pharm. Sci., 13, 63