On the role of polarizability in QSAR

Pauling, 1960 Kutter, 1969, Arch. Biochem. Biophys., 135, 626, 10.1016/0003-9861(69)90523-2 ClogP and C-QSAR program, BioByte Corp. 201 W. Fourth St., Suit 204, Claremont, CA 91711. www.biobyte.com Hansch, 2003, J. Chem. Inf. Comput. Sci., 43, 120, 10.1021/ci020378b Hansch, 2003, J. Chem. Inf. Comput. Sci., 43, 1647, 10.1021/ci030289e King, 1987 Vaillancourt, 2000, Bioorg. Med. Chem., 10, 2079, 10.1016/S0960-894X(00)00402-9 Schlitzer, 2000, Bioorg. Med. Chem., 8, 2399, 10.1016/S0968-0896(00)00173-5 Hanessian, 2001, J. Med. Chem., 44, 3066, 10.1021/jm010097f Szardenings, 1998, J. Med. Chem., 41, 2194, 10.1021/jm980133j Foley, 2001, Bioorg. Med. Chem., 11, 969, 10.1016/S0960-894X(01)00104-4 Kaczmarek, 1999, Bioorg. Med. Chem., 7, 2457, 10.1016/S0968-0896(99)00200-X Keller, 2001, Chem. Pharm. Bull., 49, 1009, 10.1248/cpb.49.1009 Hanessian, 2001, J. Med. Chem., 44, 3074, 10.1021/jm010096n Suzuki, 2000, J. Enzyme Inhib., 15, 357, 10.1080/14756360009040693 Venhorst, 2000, Drug Metab. Dispos., 28, 1524 Lee, 1991, J. Med. Chem., 34, 2474, 10.1021/jm00112a024 Shin, 2004, J. Med. Chem., 47, 792, 10.1021/jm020545z Darnnhardt, 2000, Eur. J. Med. Chem., 35, 499, 10.1016/S0223-5234(00)00150-1 Hirokawa, 2003, J. Med. Chem., 46, 702, 10.1021/jm020270n Gharagozloo, 2002, J. Med. Chem., 45, 1259, 10.1021/jm010946z Santini, 2003, Bioorg. Med. Chem. Lett., 13, 1277, 10.1016/S0960-894X(03)00115-X Hu, 2003, Water Res., 37, 1213, 10.1016/S0043-1354(02)00378-0 Mattson, 2003, Bioorg. Med. Chem. Lett., 13, 285, 10.1016/S0960-894X(02)00879-X Doherty, 1995, J. Med. Chem., 38, 1259, 10.1021/jm00008a002 Somanadhan, 2002, Bioorg. Med. Chem., 10, 207, 10.1016/S0968-0896(01)00267-X Meier, 2002, Bioorg. Med. Chem., 10, 2535, 10.1016/S0968-0896(02)00115-3 Street, 1993, J. Med. Chem., 36, 1529, 10.1021/jm00063a003 Kimura, 2003, Bioorg. Med. Chem., 11, 1621, 10.1016/S0968-0896(03)00061-0 Hahin, 2001, J. Membr. Biol., 180, 137, 10.1007/s002320010065 Kamlet, 1988, Quant. Struct.–Act. Relat., 7, 71, 10.1002/qsar.19880070204 Dinno, 1972, Proc. Soc. Exptl. Biol. Med., 141, 397, 10.3181/00379727-141-36784 Goldbaum, 1954, J. Pharmacol. Exp. Ther., 111, 197 Faissat, 2003, Bioorg. Med. Chem., 11, 325, 10.1016/S0968-0896(02)00458-3 Chen, 2002, Bioorg. Med. Chem., 10, 2381, 10.1016/S0968-0896(02)00067-6 Miko, 1980, Biologia (Bratislava), 35, 861 Medina, 1998, Bioorg. Med. Chem. Lett., 8, 2653, 10.1016/S0960-894X(98)00477-6 Diana, 2003, Bioorg. Med. Chem., 11, 2371, 10.1016/S0968-0896(03)00145-7 Deady, 2000, Bioorg. Med. Chem., 8, 977, 10.1016/S0968-0896(00)00039-0 Tobe, 2003, Bioorg. Med. Chem., 11, 609, 10.1016/S0968-0896(02)00338-3 Deasi, 1995, Bioorg. Med. Chem., 5, 105, 10.1016/0960-894X(94)00466-S Matsuda, 2003, Bioorg. Med. Chem., 11, 1995, 10.1016/S0968-0896(03)00067-1 Muller, 1996, J. Med. Chem., 39, 3238, 10.1021/jm9603328 Mugnaini, 2003, Bioorg. Med. Chem., 11, 357, 10.1016/S0968-0896(02)00460-1 Pernak, 2001, Eur. J. Med. Chem., 36, 899, 10.1016/S0223-5234(01)80005-2 Williamson, 1967, Science, 158, 1694, 10.1126/science.158.3809.1694 Nielsen, 2002, J. Med. Chem., 45, 4171, 10.1021/jm0208121 Guo, 1993, Carcinogenesis, 14, 1167, 10.1093/carcin/14.6.1167 Perrone, 1997, Eur. J. Med. Chem., 32, 739, 10.1016/S0223-5234(97)88916-7 Hansch, 1968, J. Med. Chem., 11, 1, 10.1021/jm00307a001 Watari, 1988, J. Pharmacokinet. Biopharm., 16, 279, 10.1007/BF01062138 Sabljic, 1983, Bull. Environ. Contam. Toxicol., 30, 80, 10.1007/BF01610102 Safwat, 1988, Egypt. J. Pharm. Sci., 29, 151