Effect of diclofenac on germ cell apoptosis following testicular ischemia-reperfusion injury in a rat

Baccetti B, Collodel G, Piomboni P (1996) Apoptosis in human ejaculated sperm cells (notulae seminologicae 9). Submicrosc Cytol Pathol 28:587–596

Bartke A (1995) Apoptosis of male germ cells, a generalized or cell type-specific phenomenon. Endocrinology 136:3–4

Bartsch G, Frank S, Marberger H, Mikuz G (1980) Testicular torsion: late results with special regard to fertility and endocrine function. J Urol 124:375–378

Cheuk BL, Chew SB, Fiscus RR, Wong PY (2002) Cyclooxygenase-2 regulates apoptosis in rat epididymis through prostaglandin D2. Biol Reprod 66:374–380

Chung CK, Koo HN, Chung KY, Shin T, Kim HR, Chae HJ, An NH, Kim CH, Kim HM (2000) Inhibitory effect of sodium salicylate on nitric oxide production from TM4 sertoli cells. Int J Immunopharmacol 22:685–692

Filho DW, Torres MA, Bordin AL, Crezcynski-Pasa TB, Boveris A (2004) Spermatic cord torsion, reactive oxygen and nitrogen species and ischemia-reperfusion injury. Mol Aspects Med 25:199–210

Harrison RG, Lewis-Jones DI, Moreno de Marval MJ, Connolly RC (1981) Mechanism of damage to the contralateral testis in rats with an ischemic testis. Lancet 2:723–725

Hikim AP, Lue Y, Yamamoto CM, Vera Y, Rodriguez S, Yen PH, Soeng K, Wang C, Swerdloff RS (2003) Key apoptotic pathways for heat-induced programmed germ cell death in the testis. Endocrinology 144:3167–3175

Johnsen SG (1970) Testicular biopsy score count—a method for registration of spermatogenesis in human testes: normal values and results in 335 hypogonadal males. Hormones 1:2–25

Keller JJ, Giardiello FM (2003) Chemoprevention strategies using NSAIDs and COX-2 inhibitors. Cancer Biol Ther 2(4 Suppl 1):S140–S149

Kimura M, Itoh N, Takagi S, Sasao T, Takahashi A, Masumori N, Tsukamoto T (2003) Balance of apoptosis and proliferation of germ cells related to spermatogenesis in aged men. J Androl 24:185–191

Lysiak JJ, Nguyen QA, Turner TT (2002) Peptide and nonpeptide reactive oxygen scavengers provide partial rescue of the testis after torsion. J Androl 23:400–409

Lysiak JJ, Nguyen QA, Kirby JL, Turner TT (2003) Ischemia-reperfusion of the murine testis stimulates the expression of proinflammatory cytokines and activation of C-Jun N-terminal kinase in a pathway to E-selectin expression. Biol Reprod 69:202–210

Miller DC, Peron SE, Keck RW, Kropp KA (1990) Effects of hypothermia on testicular ischemia. J Urol 143:1046–1048

Mirshafiey A, Khorramizadeh MR, Saadat F, Rehm BH (2004) Chemopreventive effect of M2000, a new anti-inflammatory agent. Med Sci Monit 10:PI105–PI109

Modi DN, Sane S, Bhartiya D (2003) Accelerated germ cell apoptosis in sex chromosome aneuploid fetal human gonads. Mol Hum Reprod 9:219–225

Puri P, Barton D, O’Donnell B (1985) Prepubertal testicular torsion: subsequent fertility. J Pediatr Surg 12:563–570

Smith WL, DeWitt DL, Garavito RM (2000) Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem 69:145–182

Sukhotnik I, Miselevich I, Lurie M, Nativ O, Coran AG, Mogilner G (2005) The time relationship between ipsilateral testicular ischemia-reperfusion and germ cell apoptosis in the contralateral testis in rat. Pediatr Surg Int 15:1–5

Tarnawski AS, Jones MK (2003) Inhibition of angiogenesis by NSAIDs: molecular mechanisms and clinical implications. Mol Med 81:627–636

Tomomasa H, Adachi Y, Oshio S, Umeda T, Irie H, Ishikawa H (2002) Germ cell apoptosis in undescended testis: the origin of its impaired spermatogenesis in the TS inbred rat. Urol 168:343–347

Turner TT, Tung KS, Tomomasa H, Wilson LW (1997) Acute testicular ischemia results in germ cell-specific apoptosis in the rat. Biol Reprod 57:1267–1274

Vane JR, Botting RM (1996) Mechanism of action of anti-inflammatory drugs. Scand J Rheumatol Suppl 102:9–21

Walch L, Morris PL (2002) Cyclooxygenase 2 pathway mediates IL-1beta regulation of IL-1alpha, -1beta, and IL-6 mRNA levels in Leydig cell progenitors. Endocrinology 143:3276–3283