TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis

Cancer Cell - Tập 20 - Trang 25-38 - 2011
Cyril Quivoron1,2,3, Lucile Couronné1,2,3, Véronique Della Valle1,2,3, Cécile K. Lopez1,2,3, Isabelle Plo2,3,4, Orianne Wagner-Ballon4,5, Marcio Do Cruzeiro6, Francois Delhommeau4,7, Bertrand Arnulf8, Marc-Henri Stern9, Lucy Godley10, Paule Opolon3, Hervé Tilly11, Eric Solary2,3,4, Yannis Duffourd3, Philippe Dessen1,2,3, Hélène Merle-Beral12, Florence Nguyen-Khac12, Michaëla Fontenay13, William Vainchenker2,3,4
1INSERM, U985, Villejuif 94805, France
2Université Paris-Sud, Orsay 91400, France
3Institut Gustave Roussy, Villejuif 94805, France
4INSERM, U1009, Villejuif 94805, France
5Hôpital Henri Mondor, Créteil 94000, France
6Plateforme de Recombinaison Homologue, Institut Cochin, INSERM U1016; Centre National de la Recherche Scientifique (CNRS) Unité Mixte de Recherche (UMR) 8104; Université Paris Descartes, Faculté de Médecine Paris Descartes, 75014, Paris, France
7Université Pierre et Marie Curie, Hôpital Saint Antoine, Paris 75005, France
8A 3963, Université Paris VII, Hôpital Saint-Louis, Paris 75010, France
9INSERM, U830, Institut Curie, Paris 75005, France
10Department of Medicine, The University of Chicago, Chicago, IL 60637, USA
11INSERM, U918, Université de Rouen, Centre Henri Becquerel, Rouen 76038, France
12Service d'Hématologie Biologique, Hôpital Pitié-Salpêtrière, APHP; Université Pierre et Marie Curie-Paris 6; INSERM U872, Paris 75005, France
13Assistance Publique-Hôpitaux de Paris, Service d'Hématologie Biologique, Groupe Hospitalier Broca-Cochin-Hôtel-Dieu; Institut Cochin, Département d'Immuno-Hématologie, INSERM U1016, Centre National de la Recherche Scientifique (CNRS) Unité Mixte de Recherche (UMR) 8104, Université Paris Descartes, Faculté de Médecine Paris Descartes, Paris 75014, France

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