Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride ionophore complex

Neuroscience & Biobehavioral Reviews - Tập 14 Số 3 - Trang 315-322 - 1990
Delia Belelli1, Nancy C. Lan2, Kelvin W. Gee2
1Division of Biological Sciences, School of Pharmacy, University of Southern California, Los Angeles 90033.
2Division of Biological Sciences, School of Pharmacy University of Southern California, Los Angeles, CA 90033, USA

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Almqvist, 1955, The rhythm of epileptic attacks and its relationship to the menstrual cycle, Acta Psychiatr., 30, 1

Backstrom, 1976, Epileptic seizures in women related to plasma estrogen and progesterone during the menstrual cycle, Acta Neurol. Scand., 54, 321, 10.1111/j.1600-0404.1976.tb04363.x

Backstrom, 1985, Ovarian steroid hormones: effects of mood, behavior and brain excitability, Acta Obstet. Gynecol. Scand. Suppl., 130, 19, 10.3109/00016348509157142

Barker, 1986, Voltage clamp studies of the potentiation of GABA-activated chloride conductance by alphaxalone and a reduced metabolite of progesterone, J. Physiol., 355, 838

Barker, 1981, GABA analogs activate channels of different duration on cultured mouse spinal neurons, Science, 212, 358, 10.1126/science.6259733

Belelli, 1989, Anticonvulsant profile of the progesterone metabolite 5α-pregnan-3α-ol-20-one, Eur. J. Pharmacol., 166, 325, 10.1016/0014-2999(89)90077-0

Belelli, 1989, 5α-pregnan-3α,20α-diol behaves like a partial agonist in the modulation of GABA-stimulated chloride ion uptake by synaptoneurosomes, Eur. J. Pharmacol., 167, 173, 10.1016/0014-2999(89)90760-7

Belelli, 1990, Heterotropic cooperativity between putative recognition sites for progesterone metabolites and the atypical benzodiazepine Ro5 4864, J. Neurochem., 10.1111/j.1471-4159.1990.tb08824.x

Bellville, 1956, Comparison of the electroencephalographic patterns during steroid and barbiturate narcosis, Br. J. Anesth., 28, 50, 10.1093/bja/28.2.50

Blackham, 1970, Response of female mice to anticonvulsants after pretreatment with sex steroids, J. Pharm. Pharmacol., 22, 304, 10.1111/j.2042-7158.1970.tb08524.x

Canick, 1986, Localization of aromatose and 5α-reductase to neuronal and non-neuronal cells in the fetal rat hypothalamus, Brain Res., 372, 277, 10.1016/0006-8993(86)91135-2

Casalotti, 1986, Separate subunits for agonist and benzodiazepine binding in the γ-aminobutyric acidA receptor oligomer, J. Biol. Chem., 261, 15013, 10.1016/S0021-9258(18)66821-8

Cottrell, 1987, Alphaxalone potentiates GABA and activates the GABAA receptor of mouse spinal neurones in culture, J. Physiol., 382

Cottrell, 1987, Modulation of GABAA receptor activity by alphaxalone, Br. J. Pharmacol., 90, 491, 10.1111/j.1476-5381.1987.tb11198.x

Craig, 1966, Anticonvulsant activity of steroids: separability of anticonvulsant from hormonal effects, J. Pharmacol. Exp. Ther., 153, 337

Crawley, 1986, Anxiolytic activity of an endogenous adrenal steroid, Brain Res., 398, 382, 10.1016/0006-8993(86)91500-3

Dalton, 1984

Fesik, 1986, Geometric requirements for membrane perturbation and anesthetic activity: conformational analysis of alphaxalone and delta-16-alphaxalone and HNMR studies on their interactions with model membranes, Mol. Pharmacol., 27, 624

Fuchs, 1988, Various proteins from rat brain, specifically and irreversibly labeled by [3H]flunitrazepam, are distinct α-subunits of the GABA-benzodiazepine receptor complex, Neurosci. Lett., 90, 314, 10.1016/0304-3940(88)90208-X

Gee, 1988, Steroid modulation of the GABA/benzodiazepine receptor-linked chloride ionophore, Mol. Neurobiol., 2, 291, 10.1007/BF02935636

Gee, 1988, Steroid modulation of the chloride ionophore in rat brain: Structure activity requirements, regional dependence and mechanism of action, J. Pharmacol. Exp. Ther., 246, 803

Gee, 1987, Gamma-aminobutyric acid-dependent modulation of the chloride ionophore by steroids in rat brain, Eur. J. Pharmacol., 136, 419, 10.1016/0014-2999(87)90317-7

Gyermek, 1975, Steroid anesthetics, Anesthesiology, 42, 331, 10.1097/00000542-197503000-00017

Harrison, 1984, Modulation of the GABA receptor complex by a steroid anesthetic, Brain Res., 323, 287, 10.1016/0006-8993(84)90299-3

Harrison, 1987, Structure-activity relationships for steroid interaction with the gamma-aminobutyric acid-A receptor complex, J. Pharmacol. Exp. Ther., 24, 346

Hogskilde, 1988, Anticonvulsive properties of pregnanolone emulsion compared with althesin and thiopentone in mice, Br. J. Anesth., 61, 462, 10.1093/bja/61.4.462

Holmes, 1987, Relationship of endocrine function to inhibition of kindling, Dev. Brain Res., 16, 55, 10.1016/0165-3806(84)90062-2

Holzbauer, 1975, Physiological variations in the ovarian production of 5α-pregnane derivatives with sedative properties in the rat, J. Steroid Biochem., 6, 1307, 10.1016/0022-4731(75)90357-X

Karavolas, 1984, Progesterone processing by neuroendocrine structures, 149

Krieger, 1984, 3α-hydroxy steroid oxidoreductase in rat brain, J. Neurochem., 42, 887, 10.1111/j.1471-4159.1984.tb02767.x

Krieger, 1989, Non-neuronal localization for steroid converting enzyme: 3α-hydroxy steroid oxidoreductase in olfactory tubercle of rat brain, J. Neurochem., 52, 1866, 10.1111/j.1471-4159.1989.tb07269.x

Laidlaw, 1956, Catamenial epilepsy, Lancet, 2, 1235, 10.1016/S0140-6736(56)90003-4

Lambert, 1987, Actions of synthetic and endogenous steroids on the GABAA receptor, Trends Pharmacol. Sci., 8, 224, 10.1016/0165-6147(87)90067-8

Lan, 1990, A steroid recognition site is functionally coupled to an expressed GABAA-benzodiazepine receptor, Eur. J. Pharmacol., 10.1016/0014-2999(90)92382-S

Landgren, 1987, The effect of progesterone and its metabolites on the interictal epileptiform discharge in the cat's cerebral cortex, Acta Physiol. Scand., 131, 33, 10.1111/j.1748-1716.1987.tb08202.x

Levitan, 1988, Structural and functional basis for GABAA receptor heterogeneity, Nature, 335, 76, 10.1038/335076a0

McEwen, 1988, Glucocorticoid receptors and behavior: implications for the stress response, vol. 245, 35

Majewski, 1986, Steroid metabolites are barbiturate-like modulators of the GABA receptor, Science, 232, 1004, 10.1126/science.2422758

Mamalaki, 1987, The GABAA/benzodiazepine receptor is a heterotetramer of homologous α and β subunits, EMBO J., 6, 561, 10.1002/j.1460-2075.1987.tb04791.x

Mattson, 1981, Seizure frequency and the menstrual cycle: a clinical study, Epilepsia, 22, 242

Newmark, 1980, Catamenial epilepsy: a review, Epilepsia, 21, 281, 10.1111/j.1528-1157.1980.tb04074.x

1986

Peters, 1988, Modulation of the GABAA receptor by depressant barbiturates and pregnane steroids, Br. J. Pharmacol., 94, 1257, 10.1111/j.1476-5381.1988.tb11646.x

Pritchett, 1988, Transient expression shows ligand gating and allosteric potentiation of GABAA receptor subunits, Science, 242, 1306, 10.1126/science.2848320

Pritchett, 1989, Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology, Nature, 339, 582, 10.1038/338582a0

Rainbow, 1985, Mechanisms of gonadal steroid actions on behavior, vol. 8, 29

Rosciszewska, 1986, Ovarian hormones, anticonvulsant drugs and seizures during the menstrual cycle in women with epilepsy, J. Neurol. Neurosurg. Psychiatry, 49, 47, 10.1136/jnnp.49.1.47

Schechter, 1989, Influence of the menstrual cycle on seizures, Epilepsia, 30, 704

Schoch, 1984, A GABA/benzodiazepine receptor complex from bovine brain: Purification, reconstitution and immunological characterization, J. Recept. Res., 4, 189, 10.3109/10799898409042549

Schofield, 1980, Potentiation of inhibition by general anesthetics in neurones of the olfactory cortex in vitro, Pflugers Arch., 38, 249, 10.1007/BF00587527

Schofield, 1987, Sequence and functional expression of the GABAA receptor shows a ligandgated receptor super-family, Nature, 328, 221, 10.1038/328221a0

Selye, 1942, The antagonism between anesthetic steroid hormones and pentamethylenetetrazol (metrazol), J. Lab. Clin. Med., 27, 1051

Shivers, 1989, Two novel GABAA receptor subunits exist in distinct neuronal subpopulations, Neuron, 3, 327, 10.1016/0896-6273(89)90257-2

Sigel, 1984, A γ-aminobutyric acid/benzodiazepine receptor complex from bovine cerebral cortex: Improved purification with preservation sites and their interaction, J. Biol. Chem., 259, 7219, 10.1016/S0021-9258(17)39860-5

Sigel, 1983, A γ-aminobutyric acid/benzodiazepine receptor complex of bovine cerebral cortex, J. Biol. Chem., 258, 6965, 10.1016/S0021-9258(18)32319-6

Smith, 1987, Locally applied progesterone metabolites alter neuronal responsiveness in the cerebellum, Brain Res. Bull., 18, 739, 10.1016/0361-9230(87)90209-7

Stephenson, 1988, Understanding the GABAA receptor: A chemically gated ion channel, Biochem. J., 249, 21, 10.1042/bj2490021

Stephenson, 1986, vol. 5, 261

Swinyard, 1982, General principles: experimental detection, quantification and evaluation of anticonvulsants, 111

Turner, 1989, Steroid anesthetics and naturally occurring analogs modulate the gamma-aminobutyric acid receptor complex at a site distinct from barbiturates, J. Pharmacol. Exp. Ther., 248, 960

Vincens, 1989, A progesterone metabolite enhances the activity of the GABAA receptor complex at the pituitary level, Eur. J. Pharmacol., 168, 15, 10.1016/0014-2999(89)90627-4

Werboff, 1963, Audiogenic seizures in adult male castrated rats treated with various hormones, Endocrinology, 3, 389

Woolley, 1962, The gonad-brain relationship: effects of female sex hormones on electroshock convulsions in the rat, Endocrinology, 70, 196, 10.1210/endo-70-2-196

Woolley, 1962, Estrous and circadian periodicity and electroshock convulsions in rats, Am. J. Physiol., 202, 379, 10.1152/ajplegacy.1962.202.2.379

Worms, 1982, Gamma-aminobutyric acid (GABA) receptor stimulation. I. Neuropharmacological profiles of progabide (SL 76002) and SL 75102, with emphasis on their anticonvulsant spectra, J. Pharmacol. Exp. Ther., 220, 660

Ymer, 1989, GABAA receptor β subunit heterogeneity: functional expression of cloned cDNAs, EMBO J., 8, 1665, 10.1002/j.1460-2075.1989.tb03557.x