Induction of micronuclei by Zearalenone in Vero monkey kidney cells and in bone marrow cells of mice: protective effect of Vitamin E

Tanaka, 1988, Worldwide contamination of cereals by the Fusarium mycotoxins, Nivalenol, Deoxynivalnol, and Zearalenone. 1. Survey of 19 countries, J. Agric. Food Chem., 36, 979, 10.1021/jf00083a019 Placinta, 1999, A review of worldwide contamination of cereal grains and animal feed with Fusarium mycotoxins, Anim. Feed Sci. Technol., 78, 21, 10.1016/S0377-8401(98)00278-8 D’Mello, 1999, Fusarium mycotoxins: a review of global animal health, welfare and reproductivity, Anim. Feed Sci. Technol., 80, 183, 10.1016/S0377-8401(99)00059-0 Kuiper-Goodman, 1987, Risk assessment of the mycotoxin Zearalenone, Regul. Toxicol. Pharmacol., 7, 253, 10.1016/0273-2300(87)90037-7 Etienne, 1982, Effects of Zearalenone (F2) on oestrus activity and reproduction in gilts, J. Anim. Sci., 55, 1, 10.2527/jas1982.5511 Dacto, 1995, Zearalenone mycotoxicosis in piglets sucking sows fed contaminated grain, Vet. Hum. Toxicol., 37, 359 Hussein, 2001, Toxicity, metabolism and impact of mycotoxins on humans and animals, Toxicology, 167, 101, 10.1016/S0300-483X(01)00471-1 Saenz de Rodriguez, 1985, An epedemic of precocious development in Puerto Rican children, J. Pediatr., 107, 393, 10.1016/S0022-3476(85)80513-8 Tomaszewski, 1998, Tissue Zearalenone concentration in normal, hyperplastic and neoplastic human endometrium, Ginekol. Pol., 69, 363 M. Etienne, J.Y. Dourmand, Effects of Zearalenone or glucosinolates in the diet on reproduction in sows: a review, Livest. Prod. Sci. 40 (1994) 99–113. Ito, 1994, Effects of administration of Zearalenone on the reproductive physiology of female mice, J. Vet. Sci., 56, 1155, 10.1292/jvms.56.1155 H. Bacha, L. Chekir, F. Ellouz, R. Hadidane, E.E. Creppy, Effect of Zearalenone on fertilisation and gestation in rats. In: K.A. Scudamore (Ed.), Proceeding of UK Workshop on Occurrence in Significance of Mycotoxins, Central Science Laboratory, London, 1993, pp. 258–262. Kaliamurthy, 1997, Effects of Zearalenone on food consumption, growth, organ weight and serum testosterone level in male rats, J. Environ. Biol., 18, 115 Maaroufi, 1996, Zearalenone induces modifications of haematological and biochemical parameters in rats, Toxicon, 34, 535, 10.1016/0041-0101(96)00008-6 IARC. Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins, in: IARC (Ed.), IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol. 56, Lyon, France, 1993, pp. 397–444. Ahmed, 2001, Signal transduction through the ras/Erk pathway is essential for the mycoestrogen Zearalenone induced cell-cycle progression in MCF-7 cells, Mol. Carcinogen., 30, 88, 10.1002/1098-2744(200102)30:2<88::AID-MC1017>3.0.CO;2-E Withanage, 2001, Agonistic and antagonistic effects of Zearalenone, an estrogenic mycotoxin, on SKN, HHUA, and Hep G2 human cancer cell lines, Vet. Hum. Toxicol., 43, 6 Wehner, 1978, Lack of mutagenicity to Salmonella typhimurium of some Fusarium mycotoxins, Appl. Environ. Microbiol., 35, 659, 10.1128/AEM.35.4.659-662.1978 Ingerowski, 1981, Mutagenicity studies on veterinary anabolic drugs with Salmonella microsome test, Mutat. Res., 91, 93, 10.1016/0165-7992(81)90078-6 Krivobock, 1987, Study of the genotoxic potential of 17 mycotoxins with the SOS chromotest, Mutagenesis, 2, 433, 10.1093/mutage/2.6.433 Kuczuk, 1978, Risk assessment of the mycotoxins using Salmonella thyphimurium and Saccharomyces cerevisiae, Mutat. Res., 53, 11, 10.1016/0165-1161(78)90375-8 McGregor, 1988, Responses of the L5178YTK+/TK− mouse lymphoma cell forward mutation assay. III. 72 coded chemicals, Environ. Mol. Mutagen., 12, 85, 10.1002/em.2860120111 Galloway, 1987, Chromosome abberations and sister chromatid exchanges in Chinese hamster ovary cells: evaluation of 108 chemicals, Environ. Mol. Mutagen., 10, 1, 10.1002/em.2850100502 El Makawy, 2001, Genotoxic evaluation for the estrogenic mycotoxin Zearalenone, Reprod. Nutr. Dev., 41, 79, 10.1051/rnd:2001114 Ueno, 1976, DNA-attacking ability of carcinogenic mycotoxins in recombination-deficient mutant cells of Bacillus subtilis, Cancer Res., 36, 445 Chekir-Ghedira, 1998, Induction of SOS repair system in lysogenic bacteria by Zearalenone and its prevention by Vitamin E, Chem. Biol. Interact., 113, 15, 10.1016/S0009-2797(98)00013-1 Pfohl-Leszkowicz, 1995, Genotoxicity of Zearalenone, an oestrogenic mycotoxin: DNA adducts formation in female mouse tissues, Carcinogenesis, 16, 2315, 10.1093/carcin/16.10.2315 Gross, 1997, Retinol, ascorbic acid and α-tocopherol prevent DNA adduct formation in mice treated with the mycotoxins ochratoxin A and Zearalenone, Cancer Lett., 114, 225, 10.1016/S0304-3835(97)04669-7 Eastmond, 1989, Identification of aneuploidy inducing agents using cytokinesis-blocked human lymphocytes and an antikinetochore antibody, Environ. Mol. Mutagen., 13, 34, 10.1002/em.2850130104 Fenech, 1993, The cytokinesis-block micronucleus technique: a detailed description of the method and its application to genotoxicity studies in human postulations, Mutat. Res., 285, 35, 10.1016/0027-5107(93)90049-L Hayashi, 1983, An application of Acridine Orange fluorescent staining to micronucleus test, Mutat. Res., 120, 241, 10.1016/0165-7992(83)90096-9 Kirsch-Volders, 1997, The in vitro micronucleus test: a multi-endpoint assay to detect simultaneously mitotic delay, apoptosis, chromosome breakage, chromosome loss and non-disjunction, Mutat. Res., 392, 19, 10.1016/S0165-1218(97)00042-6 Metzler, 2001, Genotoxic potential of xenobiotic growth promoters and their metabolites, APMIS, 109, 89, 10.1034/j.1600-0463.2001.d01-108.x Bettershill, 1998, Mouse-specific carcinogens: an assessment of hazard and significance for validation of short-term carcinogenicity bioassays in transgenic mice, Hum. Exp. Toxicol., 17, 93