A bone-targeted engineered exosome platform delivering siRNA to treat osteoporosis
Tài liệu tham khảo
1993, Consensus development conference: diagnosis, prophylaxis, and treatment of osteoporosis, Am. J. Med., 94, 646, 10.1016/0002-9343(93)90218-E
Compston, 2019, Osteoporosis, Lancet, 393, 364, 10.1016/S0140-6736(18)32112-3
Black, 2016, Clinical practice. Postmenopausal osteoporosis, N. Engl. J. Med., 374, 254, 10.1056/NEJMcp1513724
Brown, 2017, Osteoporosis: staying strong, Nature, 550, s15, 10.1038/550S15a
Luhmann, 2012, Bone targeting for the treatment of osteoporosis, J. Contr. Release, 161, 198, 10.1016/j.jconrel.2011.10.001
Kusumbe, 2014, Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone, Nature, 507, 323, 10.1038/nature13145
Yang, 2017, MiR-497 approximately 195 cluster regulates angiogenesis during coupling with osteogenesis by maintaining endothelial Notch and HIF-1alpha activity, Nat. Commun., 8, 16003, 10.1038/ncomms16003
Wang, 2017, Human type H vessels are a sensitive biomarker of bone mass, Cell Death Dis., 8, 10.1038/cddis.2017.36
Song, 2020, Nuciferine prevents bone loss by disrupting multinucleated osteoclast formation and promoting type H vessel formation, Faseb. J., 34, 4798, 10.1096/fj.201902551R
Yang, 2020, Ophiopogonin D promotes bone regeneration by stimulating CD31hi EMCNhi vessel formation, Cell Prolif, 53, 10.1111/cpr.12784
Shim, 2013, Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts, J. Clin. Invest., 123, 4010, 10.1172/JCI69443
Jones, 2006, Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3, Science, 312, 1223, 10.1126/science.1126313
Wein, 2012, Control of bone resorption in mice by Schnurri-3, Proc. Natl. Acad. Sci. U. S. A., 109, 8173, 10.1073/pnas.1205848109
Xu, 2018, Targeting skeletal endothelium to ameliorate bone loss, Nat. Med., 24, 823, 10.1038/s41591-018-0020-z
Yang, 2019, Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis, Nat. Commun., 10, 2958, 10.1038/s41467-019-10809-6
Lu, 2020, Bioinspired exosome-like therapeutics and delivery nanoplatforms, Biomaterials, 242, 119925, 10.1016/j.biomaterials.2020.119925
Liu, 2020, The application of MSCs-derived extracellular vesicles in bone disorders: novel cell-free therapeutic strategy, Front. Cell. Dev. Biol., 8, 619, 10.3389/fcell.2020.00619
Phinney, 2017, Concise review: MSC-derived exosomes for cell-free therapy, Stem Cell., 35, 851, 10.1002/stem.2575
Fan, 2020, Generation of small RNA-modulated exosome mimetics for bone regeneration, ACS Nano, 14, 11973, 10.1021/acsnano.0c05122
Brennan, 2020, Biomaterials functionalized with MSC secreted extracellular vesicles and soluble factors for tissue regeneration, Adv. Funct. Mater., 30, 1909125, 10.1002/adfm.201909125
Zhang, 2015, Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis, J. Transl. Med., 13, 49, 10.1186/s12967-015-0417-0
Hu, 2015, Exosomes secreted by human-induced pluripotent stem cell-derived mesenchymal stem cells attenuate limb ischemia by promoting angiogenesis in mice, Stem Cell Res. Ther., 6, 10, 10.1186/scrt546
Alvarez-Erviti, 2011, Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes, Nat. Biotechnol., 29, 341, 10.1038/nbt.1807
Wang, 2017, Nucleolin-targeted extracellular vesicles as a versatile platform for biologics delivery to breast cancer, Theranostics, 7, 1360, 10.7150/thno.16532
Jiang, 2020, Dying tumor cell-derived exosomal miR-194-5p potentiates survival and repopulation of tumor repopulating cells upon radiotherapy in pancreatic cancer, Mol. Canc., 19, 68, 10.1186/s12943-020-01178-6
Nakashima, 2011, Evidence for osteocyte regulation of bone homeostasis through RANKL expression, Nat. Med., 17, 1231, 10.1038/nm.2452
Yan, 2019, Vascularized 3D printed scaffolds for promoting bone regeneration, Biomaterials, 190–191, 97, 10.1016/j.biomaterials.2018.10.033
Zhai, 2020, Human mesenchymal stem cell derived exosomes enhance cell‐free bone regeneration by altering their miRNAs profiles, Adv. Sci., 2001334, 10.1002/advs.202001334
Xia, 2020, Small extracellular vesicles secreted by human iPSC-derived MSC enhance angiogenesis through inhibiting STAT3-dependent autophagy in ischemic stroke, Stem Cell Res. Ther., 11, 313, 10.1186/s13287-020-01834-0
Zou, 2019, Aptamer-functionalized exosomes: elucidating the cellular uptake mechanism and the potential for cancer-targeted chemotherapy, Anal. Chem., 91, 2425, 10.1021/acs.analchem.8b05204
Guo, 2015, Erythrocyte membrane-enveloped polymeric nanoparticles as nanovaccine for induction of antitumor immunity against melanoma, ACS Nano, 9, 6918, 10.1021/acsnano.5b01042
He, 2018, Lipid-based liquid crystalline nanoparticles facilitate cytosolic delivery of siRNA via structural transformation, Nano Lett., 18, 2411, 10.1021/acs.nanolett.7b05430
Yao, 2019, Stem cell derived exosomes: microRNA therapy for age-related musculoskeletal disorders, Biomaterials, 224, 119492, 10.1016/j.biomaterials.2019.119492
Qi, 2016, Exosomes secreted by human-induced pluripotent stem cell-derived mesenchymal stem cells repair critical-sized bone defects through enhanced angiogenesis and osteogenesis in osteoporotic rats, Int. J. Biol. Sci., 12, 836, 10.7150/ijbs.14809
Tao, 2018, Modularized extracellular vesicles: the dawn of prospective personalized and precision medicine, Adv. Sci., 5, 1700449, 10.1002/advs.201700449
Li, 2017, Improved calvarial bone repair by hASCs engineered with Cre/loxP-based baculovirus conferring prolonged BMP-2 and MiR-148b co-expression, J. Tissue Eng. Regen. Med., 11, 3068, 10.1002/term.2208
Zhang, 2011, MiRNA-20a promotes osteogenic differentiation of human mesenchymal stem cells by co-regulating BMP signaling, RNA Biol., 8, 829, 10.4161/rna.8.5.16043
Sun, 2015, mir-21 overexpressing mesenchymal stem cells accelerate fracture healing in a rat closed femur fracture model, BioMed Res. Int., 2015, 412327, 10.1155/2015/412327
Yang, 2013, Tumor necrosis factor α suppresses the mesenchymal stem cell osteogenesis promoter miR-21 in estrogen deficiency-induced osteoporosis, J. Bone Miner. Res., 28, 559, 10.1002/jbmr.1798
Huang, 2012, Upregulation of miR-22 promotes osteogenic differentiation and inhibits adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells by repressing HDAC6 protein expression, Stem Cell. Dev., 21, 2531, 10.1089/scd.2012.0014
Sun, 2019, MiR-26a promotes fracture healing of nonunion rats possibly by targeting SOSTDC1 and further activating Wnt/β-catenin signaling pathway, Mol. Cell. Biochem., 460, 165, 10.1007/s11010-019-03578-9
Zhou, 2019, MicroRNA-100-5p inhibits osteoclastogenesis and bone resorption by regulating fibroblast growth factor 21, Int. J. Mol. Med., 43, 727
Guo, 2014, MiR-125a TNF receptor-associated factor 6 to inhibit osteoclastogenesis, Exp. Cell Res., 321, 142, 10.1016/j.yexcr.2013.12.001
Kim, 2015, MicroRNA-26a regulates RANKL-induced osteoclast formation, Mol. Cell., 38, 75
Nakasa, 2011, The inhibitory effect of microRNA-146a expression on bone destruction in collagen-induced arthritis, Arthritis Rheum., 63, 1582, 10.1002/art.30321
Bellera, 2014, Single intracoronary injection of encapsulated antagomir-92a promotes angiogenesis and prevents adverse infarct remodeling, J. Am. Heart Assoc., 3, 10.1161/JAHA.114.000946
Xu, 2019, Exosomal miR-423-5p mediates the proangiogenic activity of human adipose-derived stem cells by targeting Sufu, Stem Cell Res. Ther., 10, 106, 10.1186/s13287-019-1196-y
Qiao, 2019, microRNA-21-5p dysregulation in exosomes derived from heart failure patients impairs regenerative potential, J. Clin. Invest., 129, 2237, 10.1172/JCI123135
Beltrami, 2017, Human pericardial fluid contains exosomes enriched with cardiovascular-expressed MicroRNAs and promotes therapeutic angiogenesis, Mol. Ther., 25, 679, 10.1016/j.ymthe.2016.12.022
Kuehbacher, 2007, Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis, Circ. Res., 101, 59, 10.1161/CIRCRESAHA.107.153916
Sun, 2016, Osteoblast-targeting-peptide modified nanoparticle for siRNA/microRNA delivery, ACS Nano, 10, 5759, 10.1021/acsnano.5b07828
Roeder, 2016, Visual reporters for study of the osteoblast lineage, Bone, 92, 189, 10.1016/j.bone.2016.09.004
Dallas, 2013, The osteocyte: an endocrine cell and more, Endocr. Rev., 34, 658, 10.1210/er.2012-1026
Ching, 2017, Expression of odontogenic and osteogenic markers in DPSCs and SHED: a review, Curr. Stem Cell Res. Ther., 12, 71, 10.2174/1574888X11666160815095733
Li, 2020, Osteoclasts are not a source of SLIT3, Bone Res., 8, 11, 10.1038/s41413-020-0086-3
Wang, 2020, Bone-targeted extracellular vesicles from mesenchymal stem cells for osteoporosis therapy, Int. J. Nanomed., 15, 7967, 10.2147/IJN.S263756
Luo, 2019, Aptamer-functionalized exosomes from bone marrow stromal cells target bone to promote bone regeneration, Nanoscale, 11, 20884, 10.1039/C9NR02791B
Hu, 2021, Exosome-guided bone tar-geted delivery of Antagomir-188 as an anabolic therapy for bone loss, Bioact. Mater., 6, 2905, 10.1016/j.bioactmat.2021.02.014
Kimbrel, 2020, Next-generation stem cells-ushering in a new era of cell-based therapies, Nat. Rev. Drug Discov., 19, 463, 10.1038/s41573-020-0064-x
Sabapathy, 2016, hiPSC-derived iMSCs: NextGen MSCs as an advanced therapeutically active cell resource for regenerative medicine, J. Cell Mol. Med., 20, 1571, 10.1111/jcmm.12839