Prevalence of obstructive sleep apnea among patients with chronic obstructive pulmonary disease

Springer Science and Business Media LLC - Tập 15 - Trang 1-8 - 2021
Osama Ibrahim Mohammad1, Ahmed Gouda Elgazzar1, Shymaa Mohammad Mahfouz1, Marwa Elsayed Elnaggar1
1Faculty of Medicine, Benha University, Benha, Egypt

Tóm tắt

The conjunction of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) is known as overlap syndrome (OS). The coexistence of these diseases has cardiovascular morbidity and mortality. The aim of this study is to assess the prevalence of OSA in COPD patients. One hundred COPD patients (obese and non-obese) performed sleep questionnaires and polysomnograms. OSA prevalence in COPD was 50% and it increases with increasing disease severity (P < 0.001). The highest prevalence of OSA was found in obese patients with severe COPD; 90.5% of these patients have OSA. In the OSA group, obese patients were found to have significantly higher STOP-Bang Questionnaire (SBQ), Epworth Sleep Scale (ESS), modified medical research council (mMRC) dyspnea scale, apnea-hypopnea index (AHI), respiratory disturbance index (RDI), and oxygen desaturation index (ODI). Both obese and non-obese COPD patients showed significant positive correlations between AHI and smoking index (SI), SBQ, ESS, mMRC, ODI, and neck circumference (NC). From this study, it can be concluded that moderate and severe COPD patients had a higher diagnosis of sleep-disordered breathing. Also, obese-COPD patients are more susceptible to develop OSA. Name of the registry: Benha University Protocol Record Benha U123, Obstructive Sleep Apnea Prevalence in Patients With Chronic Obstructive Pulmonary Diseases. Trial registration number: NCT04903639 . Date of registry: 5/22/2021 (retrospective study).

Tài liệu tham khảo

Global Initiative for Chronic Obstructive Lung Disease (GOLD 2020); Global strategy for the diagnosis, management and prevention of COPD.NHLB/WHO global initiative for chronic obstructive pulmonary disease.http://goldcopd.org/gold-reports/. Accessed on 12 Dec.2020 Stöwhas AC, Lichtblau M, Bloch KE (2019) Obstructive Sleep Apnea Syndrome. Praxis (Bern 1994) 108(2):111–117 Flenley DC (1985) Sleep in chronic obstructive lung disease. Clin Chest Med 6:651–661 Mathers CD, Loncar D (2006) Projection of global mortality and burden of disease from 2002 to 2003. PLoS Med 3:442 Sanders MH, Newman AB, Haggerty CL et al (2003) Sleep and sleep disordered breathing in adults with predominantly mild obstructive airway disease. Am J Respir Crit Care Med 167:7–14 McNicholas WT (2016) Chronic obstructive pulmonary disease and obstructive sleep apnoea—the overlap syndrome. J Thorac dis. 8(2):236–242) Lavie P, Herer P, Lavie L (2007) Mortality risk factors in sleep apnoea: a matched case-control study. J Sleep Res 16:128–134 Mokhlesi B (2010) Obesity hypoventilation syndrome: a state-of-the-art review. Respir Care 55:1347–1362 Global Initiative for Chronic Obstructive Lung Disease (GOLD 2017); Global Strategy for the Diagnosis , Management and prevention of COPD.NHLB/WHO Global initiative for chronic obstructive pulmonary disease Anwar E, Abdulhamid F, AbdullahAl H, Abdullah A, Yosra Z, Salim B et al (2014) Validation of the Arabic version of the Epworth sleepiness scale. J Epidemiology Global Health 2014:297–302 Chung F, Yegneswaran B, Liao P, Chung SA, Vairavanathan S, Islam S et al (2008) (2008). STOP questionnaire: a tool to screen patients for obstructive sleep apnea. Anesthesiology. 108:812–821 Alyami M, Jenkins S, Lababidi H, Hill K (2015) Reliability and validity of an Arabic version of dyspnea −12 questionnaire for Saudi nationals with chronic obstructive pulmonary disease. Ann Thoracic Med 10(2):112–117 (Memon J, Manganaro SN. Obstructive Sleep-disordered Breathing. [Updated 2020 Aug 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK441909/) Kothari CR (2004). Research methodology: methods and techniques.2nd ed. New Delhi: new age international publishers; 2004 Kumar A, Gautam AK, Gautam V, Gupta AK, Yadav P, Singh NP et al (2020) Prevalence of obstructive sleep apnoea in chronic obstructive pulmonary disease patients. IJMSCR 3:370–377 Sleep Quality in COPD. [Last accessed on 31 May 2019 ]. Available from:http://www.thoracic.org/copd-guidelines/for-health professionals/management-of-stable-copd/sleep/sleep-problems-in-copd.php Gharib A (2020) The deleterious effects of chronic obstructive pulmonary disease and obstructive sleep apnea: pathophysiology and implications on treatment. Egypt J Bronchol 14:24. https://doi.org/10.1186/s43168-020-00026-x Jehan S, Zizi F, Pandi-Perumal SR, Wall S, Auguste E, Myers AK, Jean-Louis G, McFarlane SI (2017) Obstructive sleep apnea and obesity: implications for public health. Sleep Med Disord 1(4):00019 Qinhan W, Liang X, Wenjing L, Guiling X, Weiping H, Hong J, et aL. Pulmonary function influences the performance of Berlin questionnaire, modified Berlin questionnaire, and STOP-bang score for screening obstructive sleep apnea in subjects with chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis, 2020;15:1207–1216 Soler X, Gaio Eo, Frank L P, Joe W R , Jose S L , Atul M et al. High Prevalence of Obstructive Sleep Apnea in Patients with Moderate to Severe COPD. Annals ATS. 14-April-2015. as 10.1513/ 201407-336OC Gunduz C, Basoglu OK, Tasbakan MS (2018) Prevalence of overlap syndrome in chronic obstructive pulmonary disease patients without sleep apnea symptoms. Clin Respir J 12(1):105–112. https://doi.org/10.1111/crj.12493 Pissulin FDM, Pacagnelli FL, Aldá MA, Beneti R, Barros JL, Minamoto ST, Weber SAT (2018) The triad of obstructive sleep apnea syndrome, COPD, and obesity: sensitivity of sleep scales and respiratory questionnaires. J Bras Pneumol 44(3):202–206 Watson L, Vonk JM, Lofdahl CG, Schouten JP, Postma DS, Pride NB et al (2006) Predictors of lung function and its decline in mild to moderate COPD in association with gender: results from the Euroscop study. Respir Med 100:746–753 Zhu J, Zhao Z, Nie Q, Wang Y, Fu Z, Guo X et al (2020) Effect of lung function on the apnea-hypopnea index in patients with overlap syndrome: a multicenter cross-sectional study. Sleep Breath 24:1059–1066. https://doi.org/10.1007/s11325-019-01961-w Buket A, Gökşen K, Esen K (2018) (2017). Sleep quality and quality of life in patients with moderate to very severe chronic obstructive pulmonary disease. Clin Respir J 12(4):1739–1746 Nakano H, Ikeda T, Hayashi M, Ohshima E, Itoh M, Nishikata N et al (2004) Effect of boby mass index on overnight oximetry for the diagnosis of sleep apnea. Respir Med 98:421–427 Turcania P, Skrickova J, Pavlik T, Janousova E, Orban M (2015) The prevalence of obstructive sleep apnea in patients hospitalized for COPD exacerbation. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 159(3):422–428 Marin J, Soriano J, Carrizo S, Boldova A, Celli B (2010) Outcomes in patients with chronic obstructive pulmonary disease and obstructive sleep apnea: the overlap syndrome. Am J Respir Crit Care Med 182(3):325–331 Anisa I R, Siswantining T, Kamelia T and Sarwinda D. Risk Prediction Model Occurrence of Obstructive Sleep Apnea (OSA) Risk in Chronic Obstructive Pulmonary Disease patient. Case Study: Cipto Mangunkusumo Hospital. IOP Conf. Series: Journal of Physics: Conf. Series 1108 (2018) 012076 doi :https://doi.org/10.1088/1742-6596/1108/1/012076 Teodorescu M, Xie A, Sorkness CA, Robbins J, Reeder S, Gong Y et al (2014) Effects of inhaled fluticasone on upper airway during sleep and wakefulness in asthma: a pilot study. J Clin Sleep Medicine 10:183–193 Patil P, Jayalakshmi T, Abhay U, Girija N, Pragati A (2016) AHI and nocturnal desaturation in COPD patients: an early indicator for LTOT/CPAP therapy. International Journal of Current Research 8(06):33340–33344 Wan S , Jian W , Guo J , Wen M, Yi-Xuan L , Yong H (2019). Impact of obstructive sleep apnea on pulmonary hypertension in patients with chronic obstructive pulmonary disease. Chin med J (Engl). 2019;132(11):1272-82 Venkateswaran S, Tee A (2014) Overlap syndrome between chronic obstructive pulmonary disease and obstructive sleep apnoea in a southeast Asian teaching hospital. Singap Med J 55:488–492 Narasimhan M, Sharma R, Shanmuganathan A, Vallabhaneni V, Rajalingam R, Ganga N et al (2017) (2017). Correlation of severity of apnea hypopnea index (AHI) with forced expiratory volume 1(FEV1) in overlap syndrome. Journal of evidence based medicine and healthcare 4(69):4097–4104 McNicholas WT (2009) Chronic obstructive pulmonary disease and obstructive sleep apnea: overlaps in pathophysiology, systemic inflammation, and cardiovascular disease. Am J Respir Crit Care Med 180:692–700 Mengqing X, Weihua H, Minglin D, Meifang W, Junwen C, Hanzhong X et al (2019) The screening value of ESS, SACS, BQ, and SBQ on obstructive sleep apnea in patients with chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 14:2497–2505 Jaoude P, El-solh AA. Predictive factors for COPD exacerbation and mortality in patients with overlap syndrome. The clinical respiratory journal.2019;13:643–51 Lehrman SG, Limann B, Koshy A, Aronow WS, Ahn C, Maguire G (2008) Association of lung volumes with nocturnal oxygen saturation in obese persons: a possible role for therapeutic continuous positive airway pressure. Am J Ther 15(3):221–224 Peppard PE, Ward NR, Morrell MJ (2009) The impact of obesity on oxygen desaturation during sleep disordered breathing. Am J Respir Crit Care Med 180(8):778–793 Sreedharan S, Agrawal P, Rajith R, Nair S, Sarma S, Radhakrishnan A (2016) Clinical and polysomnographic predictors of severe obstructive sleep apnea in the south indian population. Ann indian Acad Neuroi 19(2):216–220 Sun WL, Wang JL, Jia GH, Mi WJ, Liao YX, Huang YW, et al. Impact of obstructive sleep apnea on pulmonary hypertension in patients with chronic obstructive pulmonary disease. chin Med J (Engl). 2019;132(11):1272–82 Izabella A, Sorin P, Stefan M (2014) Independent predictors for sleep apnea syndrome in a clinical prediction model. Chest Sleep disorders 145(3):587A Soler X, Liao S Y, Marin J M, Lorenzi-Filho G, Jen R, DeYoung P et al. Age, gender, neck circumference, and Epworth sleepiness scale do not predict obstructive sleep apnea (OSA) in moderate to severe chronic oAbstructive pulmonary disease (COPD): The challenge to predict OSA in advanced COPD. PloS one.2017; 12(5): e0177289 Sharma SK, Malik V, Vasudev C, Banga A, Mohan A, Handa KK et al (2006) Prediction of obstructive sleep apnea in patients presenting to a tertiary care center. Sleep Breath 10(3):147–154