Quiescence: Good and Bad of Stem Cell Aging
Tài liệu tham khảo
Morrison, 1994, The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype, Immunity, 1, 661, 10.1016/1074-7613(94)90037-X
Cotsarelis, 1990, Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis, Cell, 61, 1329, 10.1016/0092-8674(90)90696-C
Codega, 2014, Prospective identification and purification of quiescent adult neural stem cells from their in vivo niche, Neuron, 82, 545, 10.1016/j.neuron.2014.02.039
Basak, 2017, Induced quiescence of Lgr5+ stem cells in intestinal organoids enables differentiation of hormone-producing enteroendocrine cells, Cell Stem Cell, 20, 177, 10.1016/j.stem.2016.11.001
Buczacki, 2013, Intestinal label-retaining cells are secretory precursors expressing Lgr5, Nature, 495, 65, 10.1038/nature11965
Tian, 2011, A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable, Nature, 478, 255, 10.1038/nature10408
Cheung, 2012, Maintenance of muscle stem-cell quiescence by microRNA-489, Nature, 482, 524, 10.1038/nature10834
Hosoyama, 2011, Rb1 gene inactivation expands satellite cell and postnatal myoblast pools, J. Biol. Chem., 286, 19556, 10.1074/jbc.M111.229542
Chakkalakal, 2012, The aged niche disrupts muscle stem cell quiescence, Nature, 490, 355, 10.1038/nature11438
Kippin, 2005, p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity, Genes Dev., 19, 756, 10.1101/gad.1272305
Matsumoto, 2011, p57 is required for quiescence and maintenance of adult hematopoietic stem cells, Cell Stem Cell, 9, 262, 10.1016/j.stem.2011.06.014
Furutachi, 2013, p57 controls adult neural stem cell quiescence and modulates the pace of lifelong neurogenesis, EMBO J., 32, 970, 10.1038/emboj.2013.50
Liu, 2009, p53 regulates hematopoietic stem cell quiescence, Cell Stem Cell, 4, 37, 10.1016/j.stem.2008.11.006
Flamini, 2018, The satellite cell niche regulates the balance between myoblast differentiation and self-renewal via p53, Stem Cell Rep., 10, 970, 10.1016/j.stemcr.2018.01.007
Kim, 2017, Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression, J. Exp. Med., 214, 1901, 10.1084/jem.20160719
Gil-Perotin, 2006, Loss of p53 induces changes in the behavior of subventricular zone cells: implication for the genesis of glial tumors, J. Neurosci., 26, 1107, 10.1523/JNEUROSCI.3970-05.2006
Cheung, 2013, Molecular regulation of stem cell quiescence, Nat. Rev. Mol. Cell Biol., 14, 329, 10.1038/nrm3591
Walter, 2015, Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells, Nature, 520, 549, 10.1038/nature14131
Kalamakis, 2019, Quiescence modulates stem cell maintenance and regenerative capacity in the aging brain, Cell, 176, 1407, 10.1016/j.cell.2019.01.040
Tomasetti, 2015, Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions, Science, 347, 78, 10.1126/science.1260825
Flach, 2014, Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells, Nature, 512, 198, 10.1038/nature13619
Beerman, 2014, Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle, Cell Stem Cell, 15, 37, 10.1016/j.stem.2014.04.016
Sotiropoulou, 2010, Bcl-2 and accelerated DNA repair mediates resistance of hair follicle bulge stem cells to DNA-damage-induced cell death, Nat. Cell Biol., 12, 572, 10.1038/ncb2059
Mohrin, 2010, Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis, Cell Stem Cell, 7, 174, 10.1016/j.stem.2010.06.014
Coppe, 2008, Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor, PLoS Biol., 6, 2853, 10.1371/journal.pbio.0060301
Wyss-Coray, 2006, Inflammation in Alzheimer disease: driving force, bystander or beneficial response?, Nat. Med., 12, 1005
Franceschi, 2017, Inflammaging and ‘garb-aging’, Trends Endocrinol. Metab., 28, 199, 10.1016/j.tem.2016.09.005
Baker, 2016, Naturally occurring p16Ink4a-positive cells shorten healthy lifespan, Nature, 530, 184, 10.1038/nature16932
Campisi, 2011, Cellular senescence: a link between cancer and age-related degenerative disease?, Semin. Cancer Biol., 21, 354
Sousa-Victor, 2014, Geriatric muscle stem cells switch reversible quiescence into senescence, Nature, 506, 316, 10.1038/nature13013
Garcia-Prat, 2016, Autophagy maintains stemness by preventing senescence, Nature, 529, 37, 10.1038/nature16187
Janzen, 2006, Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a, Nature, 443, 421, 10.1038/nature05159
Choudhury, 2007, Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation, Nat. Genet., 39, 99, 10.1038/ng1937
Chang, 2016, Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice, Nat. Med., 22, 78, 10.1038/nm.4010
De Cecco, 2019, L1 drives IFN in senescent cells and promotes age-associated inflammation, Nature, 566, 73, 10.1038/s41586-018-0784-9
Guo, 2014, PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan, Cell, 156, 109, 10.1016/j.cell.2013.12.018
Smith, 2017, Regulation of life span by the gut microbiota in the short-lived African turquoise killifish, eLife, 6, 10.7554/eLife.27014
Cesar Machado, 2010, Intestinal barrier dysfunction in human pathology and aging, Curr. Pharm. Des., 22, 4645, 10.2174/1381612822666160510125331
Esplin, 2011, Chronic exposure to a TLR ligand injures hematopoietic stem cells, J. Immunol., 186, 5367, 10.4049/jimmunol.1003438
Zhao, 2014, Conversion of danger signals into cytokine signals by hematopoietic stem and progenitor cells for regulation of stress-induced hematopoiesis, Cell Stem Cell, 14, 445, 10.1016/j.stem.2014.01.007
Chen, 2019, Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation, J. Exp. Med., 216, 152, 10.1084/jem.20181505
Chambers, 2007, Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation, PLoS Biol., 5, 10.1371/journal.pbio.0050201
Ekdahl, 2003, Inflammation is detrimental for neurogenesis in adult brain, Proc. Natl. Acad. Sci. U. S. A., 100, 13632, 10.1073/pnas.2234031100
Valerio, 2002, Soluble interleukin-6 (IL-6) receptor/IL-6 fusion protein enhances in vitro differentiation of purified rat oligodendroglial lineage cells, Mol. Cell. Neurosci., 21, 602, 10.1006/mcne.2002.1208
Covacu, 2006, Nitric oxide exposure diverts neural stem cell fate from neurogenesis towards astrogliogenesis, Stem Cells, 24, 2792, 10.1634/stemcells.2005-0640
Rudolph, 1999, Longevity, stress response, and cancer in aging telomerase-deficient mice, Cell, 96, 701, 10.1016/S0092-8674(00)80580-2
Schaetzlein, 2007, Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice, Cell, 130, 863, 10.1016/j.cell.2007.08.029
Ju, 2007, Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment, Nat. Med., 13, 742, 10.1038/nm1578
Montecino-Rodriguez, 2019, Lymphoid-biased hematopoietic stem cells are maintained with age and efficiently generate lymphoid progeny, Stem Cell Rep., 12, 584, 10.1016/j.stemcr.2019.01.016
Yamamoto, 2018, Large-scale clonal analysis resolves aging of the mouse hematopoietic stem cell compartment, Cell Stem Cell, 22, 600, 10.1016/j.stem.2018.03.013
Mann, 2018, Heterogeneous responses of hematopoietic stem cells to inflammatory stimuli are altered with age, Cell Rep., 25, 2992, 10.1016/j.celrep.2018.11.056
Simsek, 2010, The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche, Cell Stem Cell, 7, 380, 10.1016/j.stem.2010.07.011
Tang, 2014, Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation, EMBO J., 33, 2782, 10.15252/embj.201488278
Pala, 2018, Distinct metabolic states govern skeletal muscle stem cell fates during prenatal and postnatal myogenesis, J. Cell Sci., 131, 10.1242/jcs.212977
Yu, 2013, Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation, Cell Stem Cell, 12, 62, 10.1016/j.stem.2012.11.022
Maryanovich, 2015, An MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fate. Nat, Commun., 6, 7901
Ito, 2014, Metabolic requirements for the maintenance of self-renewing stem cells, Nat. Rev. Mol. Cell Biol., 15, 243, 10.1038/nrm3772
Qian, 2016, The Dlk1-Gtl2 locus preserves LT-HSC function by inhibiting the PI3K–mTOR pathway to restrict mitochondrial metabolism, Cell Stem Cell, 18, 214, 10.1016/j.stem.2015.11.001
Takubo, 2013, Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells, Cell Stem Cell, 12, 49, 10.1016/j.stem.2012.10.011
Ho, 2017, Autophagy maintains the metabolism and function of young and old stem cells, Nature, 543, 205, 10.1038/nature21388
Lozoya, 2018, Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation, PLoS Biol., 16, 10.1371/journal.pbio.2005707
Horvath, 2013, DNA methylation age of human tissues and cell types, Genome Biol., 14, R115, 10.1186/gb-2013-14-10-r115
Luchsinger, 2016, Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential, Nature, 529, 528, 10.1038/nature16500
de Almeida, 2017, Dye-independent methods reveal elevated mitochondrial mass in hematopoietic stem cells, Cell Stem Cell, 21, 725, 10.1016/j.stem.2017.11.002
Ryall, 2015, The NAD+-dependent SIRT1 deacetylase translates a metabolic switch into regulatory epigenetics in skeletal muscle stem cells, Cell Stem Cell, 16, 171, 10.1016/j.stem.2014.12.004
Pallafacchina, 2010, An adult tissue-specific stem cell in its niche: a gene profiling analysis of in vivo quiescent and activated muscle satellite cells, Stem Cell Res., 4, 77, 10.1016/j.scr.2009.10.003
Liu, 2013, Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging, Cell Rep., 4, 189, 10.1016/j.celrep.2013.05.043
Knobloch, 2017, A fatty acid oxidation-dependent metabolic shift regulates adult neural stem cell activity, Cell Rep., 20, 2144, 10.1016/j.celrep.2017.08.029
Rocheteau, 2012, A subpopulation of adult skeletal muscle stem cells retains all template DNA strands after cell division, Cell, 148, 112, 10.1016/j.cell.2011.11.049
Rodgers, 2014, mTORC1 controls the adaptive transition of quiescent stem cells from G0 to GAlert, Nature, 510, 393, 10.1038/nature13255
Wust, 2018, Metabolic maturation during muscle stem cell differentiation is achieved by miR-1/133a-mediated inhibition of the Dlk1-Dio3 mega gene cluster, Cell Metab., 27, 1026, 10.1016/j.cmet.2018.02.022
Leeman, 2018, Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging, Science, 359, 1277, 10.1126/science.aag3048
Mortensen, 2011, The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance, J. Exp. Med., 208, 455, 10.1084/jem.20101145
Mana, 2017, Dietary regulation of adult stem cells, Curr. Stem Cell Rep., 3, 1, 10.1007/s40778-017-0072-x
Mattison, 2017, Caloric restriction improves health and survival of rhesus monkeys, Nat. Commun., 8, 14063, 10.1038/ncomms14063
Cerletti, 2012, Short-term calorie restriction enhances skeletal muscle stem cell function, Cell Stem Cell, 10, 515, 10.1016/j.stem.2012.04.002
Boldrin, 2017, The effect of calorie restriction on mouse skeletal muscle is sex, strain and time-dependent, Sci. Rep., 7, 5160, 10.1038/s41598-017-04896-y
Tang, 2016, Dietary restriction improves repopulation but impairs lymphoid differentiation capacity of hematopoietic stem cells in early aging, J. Exp. Med., 213, 535, 10.1084/jem.20151100
Lazare, 2017, Lifelong dietary intervention does not affect hematopoietic stem cell function, Exp. Hematol., 53, 26, 10.1016/j.exphem.2017.06.002
Forni, 2017, Caloric restriction promotes structural and metabolic changes in the skin, Cell Rep., 20, 2678, 10.1016/j.celrep.2017.08.052
Ermolaeva, 2018, Cellular and epigenetic drivers of stem cell ageing, Nat. Rev. Mol. Cell Biol., 19, 594, 10.1038/s41580-018-0020-3
Sun, 2014, Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal, Cell Stem Cell, 14, 673, 10.1016/j.stem.2014.03.002
Schworer, 2016, Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals, Nature, 540, 428, 10.1038/nature20603
O’Sullivan, 2010, Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres, Nat. Struct. Mol. Biol., 17, 1218, 10.1038/nsmb.1897
Funayama, 2006, Loss of linker histone H1 in cellular senescence, J. Cell Biol., 175, 869, 10.1083/jcb.200604005
Takahashi, 2012, DNA damage signaling triggers degradation of histone methyltransferases through APC/CCdh1 in senescent cells, Mol. Cell, 45, 123, 10.1016/j.molcel.2011.10.018
Gomes, 2013, Declining NAD+ induces a pseudohypoxic state disrupting nuclear–mitochondrial communication during aging, Cell, 155, 1624, 10.1016/j.cell.2013.11.037
Blagosklonny, 2013, Aging is not programmed: genetic pseudo-program is a shadow of developmental growth, Cell Cycle, 12, 3736, 10.4161/cc.27188
Martin, 2014, Ageing as developmental decay: insights from p16INK4a, Trends Mol. Med., 20, 667, 10.1016/j.molmed.2014.09.008
Brack, 2007, Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis, Science, 317, 807, 10.1126/science.1144090
Carlson, 2008, Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells, Nature, 454, 528, 10.1038/nature07034
Conboy, 2003, Notch-mediated restoration of regenerative potential to aged muscle, Science, 302, 1575, 10.1126/science.1087573
Price, 2014, Inhibition of JAK–STAT signaling stimulates adult satellite cell function, Nat. Med., 20, 1174, 10.1038/nm.3655
Cosgrove, 2014, Rejuvenation of the muscle stem cell population restores strength to injured aged muscles, Nat. Med., 20, 255, 10.1038/nm.3464
Sugimura, 2012, Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche, Cell, 150, 351, 10.1016/j.cell.2012.05.041
Nemeth, 2007, Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation, Proc. Natl. Acad. Sci. U. S. A., 104, 15436, 10.1073/pnas.0704747104
Povinelli, 2014, Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor, Stem Cells, 32, 105, 10.1002/stem.1513
Florian, 2013, A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing, Nature, 503, 392, 10.1038/nature12631
Shea, 2010, Sprouty1 regulates reversible quiescence of a self-renewing adult muscle stem cell pool during regeneration, Cell Stem Cell, 6, 117, 10.1016/j.stem.2009.12.015
Bigot, 2015, Age-associated methylation suppresses SPRY1, leading to a failure of re-quiescence and loss of the reserve stem cell pool in elderly muscle, Cell Rep., 13, 1172, 10.1016/j.celrep.2015.09.067
Dou, 2017, Cytoplasmic chromatin triggers inflammation in senescence and cancer, Nature, 19, 402, 10.1038/nature24050