Improving the Pipeline for Developing and Testing Pharmacological Treatments in Pregnancy

S Ito, 2016, Pregnancy-associated changes in pharmacokinetics: a systematic review, PLoS Med

C Therapontos, 2009, Thalidomide induces limb defects by preventing angiogenic outgrowth during early limb formation, Proceedings of the National Academy of Sciences of the United States of America, 106, 8573, 10.1073/pnas.0901505106

A Goodman, 2011, The long-term effects of in utero exposures—the DES story, The New England journal of medicine, 364, 2083, 10.1056/NEJMp1104409

NM Fisk, 2008, Market failure and the poverty of new drugs in maternal health, PLoS Med, 5, e22, 10.1371/journal.pmed.0050022

DD Glover, 2003, Prescription, over-the-counter, and herbal medicine use in a rural, obstetric population, American journal of obstetrics and gynecology, 188, 1039, 10.1067/mob.2003.223

C Herring, 2010, Off-label prescribing during pregnancy in the UK: an analysis of 18,000 prescriptions in Liverpool Women's Hospital, The International journal of pharmacy practice, 18, 226, 10.1211/ijpp.18.04.0007

EO van Vliet, 2014, Preterm labor: current pharmacotherapy options for tocolysis, Expert opinion on pharmacotherapy, 15, 787, 10.1517/14656566.2014.889684

UK Teratology Information Service. <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://www.uktis.org/" xlink:type="simple">http://www.uktis.org/</ext-link> (accessed 8 September 2016)

C Chambers, 2011, The role of teratology information services in screening for teratogenic exposures: challenges and opportunities, American journal of medical genetics Part C, Seminars in medical genetics, 157C, 195, 10.1002/ajmg.c.30303

KM Godfrey, 2001, Fetal programming and adult health, Public health nutrition, 4, 611, 10.1079/PHN2001145

DA Van Riet-Nales, 2016, Paediatric Drug Development and Formulation Design-a European Perspective, AAPS PharmSciTech

Food U.S. and Drug Administration. Pregnancy and Lactation Labeling (Drugs) Final Rule. <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://www.fda.gov/Drugs/DevelopmentApprovalProcess/DevelopmentResources/Labeling/ucm093307.htm" xlink:type="simple">http://www.fda.gov/Drugs/DevelopmentApprovalProcess/DevelopmentResources/Labeling/ucm093307.htm</ext-link> (accessed 8 September 2016)

David AL, Thornton S, Sutcliffe A, Williams P. Developing New Pharmaceutical Treatments for Obstetric Conditions: Scientific Impact Paper No. 50. Royal College of Obstetricians and Gynaecologists, 2015. <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="https://www.rcog.org.uk/globalassets/documents/guidelines/scientific-impact-papers/sip-50.pdf" xlink:type="simple">https://www.rcog.org.uk/globalassets/documents/guidelines/scientific-impact-papers/sip-50.pdf</ext-link>