Depletion of Three BMP Antagonists from Spemann's Organizer Leads to a Catastrophic Loss of Dorsal Structures

Developmental Cell - Tập 8 - Trang 401-411 - 2005
Mustafa K. Khokha1,2, Joanna Yeh1, Timothy C. Grammer1, Richard M. Harland1
1Department of Molecular and Cell Biology, University of California, Berkeley, 142 LSA, Berkeley, California 94720
2Department of Pediatrics, School of Medicine, University of California, San Francisco, 505 Parnassus Avenue, San Francisco, California 94143

Tài liệu tham khảo

Agius, 2000, Endodermal Nodal-related signals and mesoderm induction in Xenopus, Development, 127, 1173, 10.1242/dev.127.6.1173 Amaya, 1998, Frog genetics: Xenopus tropicalis jumps into the future, Trends Genet., 14, 253, 10.1016/S0168-9525(98)01506-6 Bachiller, 2000, The organizer factors Chordin and Noggin are required for mouse forebrain development, Nature, 403, 658, 10.1038/35001072 Bachiller, 2003, The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome, Development, 130, 3567, 10.1242/dev.00581 Baker, 1999, Wnt signaling in Xenopus embryos inhibits bmp4 expression and activates neural development, Genes Dev., 13, 3149, 10.1101/gad.13.23.3149 Bauer, 1998, Follistatin and noggin are excluded from the zebrafish organizer, Dev. Biol., 204, 488, 10.1006/dbio.1998.9003 Blitz, 2003, Twisted gastrulation loss-of-function analyses support its role as a BMP inhibitor during early Xenopus embryogenesis, Development, 130, 4975, 10.1242/dev.00709 Brannon, 1997, A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus, Genes Dev., 11, 2359, 10.1101/gad.11.18.2359 Chang, 2001, Twisted gastrulation can function as a BMP antagonist, Nature, 410, 483, 10.1038/35068583 Collavin, 2003, The secreted Frizzled-related protein Sizzled functions as a negative feedback regulator of extreme ventral mesoderm, Development, 130, 805, 10.1242/dev.00306 De Robertis, 2000, The establishment of Spemann's organizer and patterning of the vertebrate embryo, Nat. Rev. Genet., 1, 171, 10.1038/35042039 Feldman, 1998, Zebrafish organizer development and germ-layer formation require nodal-related signals, Nature, 395, 181, 10.1038/26013 Gimlich, 1983, Cell lineage and the induction of second nervous systems in amphibian development, Nature, 306, 471, 10.1038/306471a0 Gimlich, 1984, Early cellular interactions promote embryonic axis formation in Xenopus laevis, Dev. Biol., 104, 117, 10.1016/0012-1606(84)90042-3 Haramoto, 2004, Xenopus tropicalis nodal-related gene 3 regulates BMP signaling: an essential role for the pro-region, Dev. Biol., 265, 155, 10.1016/j.ydbio.2003.09.015 Harland, 1997, Formation and function of Spemann's organizer, Annu. Rev. Cell Dev. Biol., 13, 611, 10.1146/annurev.cellbio.13.1.611 Harland, 1991, In situ hybridization: an improved whole-mount method for Xenopus embryos, Methods Cell Biol., 36, 685, 10.1016/S0091-679X(08)60307-6 Heasman, 1994, Overexpression of cadherins and underexpression of beta-catenin inhibit dorsal mesoderm induction in early Xenopus embryos, Cell, 79, 791, 10.1016/0092-8674(94)90069-8 Heasman, 2000, Beta-catenin signaling activity dissected in the early Xenopus embryo: a novel antisense approach, Dev. Biol., 222, 124, 10.1006/dbio.2000.9720 Hirsch, 2002, Xenopus, the next generation: X. tropicalis genetics and genomics, Dev. Dyn., 225, 422, 10.1002/dvdy.10178 Khokha, 2002, Techniques and probes for the study of Xenopus tropicalis development, Dev. Dyn., 225, 499, 10.1002/dvdy.10184 Klingensmith, 1999, Neural induction and patterning in the mouse in the absence of the node and its derivatives, Dev. Biol., 216, 535, 10.1006/dbio.1999.9525 Kuroda, 2004, Neural induction in Xenopus: requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and Cerberus, PLoS Biol., 2, E92, 10.1371/journal.pbio.0020092 Lamb, 1993, Neural induction by the secreted polypeptide noggin, Science, 262, 713, 10.1126/science.8235591 Leung, 2003, bozozok directly represses bmp2b transcription and mediates the earliest dorsoventral asymmetry of bmp2b expression in zebrafish, Development, 130, 3639, 10.1242/dev.00558 Matzuk, 1995, Multiple defects and perinatal death in mice deficient in follistatin, Nature, 374, 360, 10.1038/374360a0 McKendry, 1997, LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter, Dev. Biol., 192, 420, 10.1006/dbio.1997.8797 McMahon, 1998, Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite, Genes Dev., 12, 1438, 10.1101/gad.12.10.1438 Niehrs, 2004, Regionally specific induction by the Spemann-Mangold organizer, Nat. Rev. Genet., 5, 425, 10.1038/nrg1347 Oelgeschlager, 2003, Chordin is required for the Spemann organizer transplantation phenomenon in Xenopus embryos, Dev. Cell, 4, 219, 10.1016/S1534-5807(02)00404-5 Ohta, 2004, Tsukushi functions as an organizer inducer by inhibition of BMP activity in cooperation with chordin, Dev. Cell, 7, 347, 10.1016/j.devcel.2004.08.014 Onichtchouk, 1999, Silencing of TGF-beta signalling by the pseudoreceptor BAMBI, Nature, 401, 480, 10.1038/46794 Rastegar, 1999, Transcriptional regulation of Xvent homeobox genes, Mech. Dev., 81, 139, 10.1016/S0925-4773(98)00239-1 Ross, 2001, Twisted gastrulation is a conserved extracellular BMP antagonist, Nature, 410, 479, 10.1038/35068578 Rudnicki, 1993, MyoD or Myf-5 is required for the formation of skeletal muscle, Cell, 75, 1351, 10.1016/0092-8674(93)90621-V Sasai, 1994, Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes, Cell, 79, 779, 10.1016/0092-8674(94)90068-X Sater, 1990, The role of the dorsal lip in the induction of heart mesoderm in Xenopus laevis, Development, 108, 461, 10.1242/dev.108.3.461 Schneider, 1999, Spatially distinct head and heart inducers within the Xenopus organizer region, Curr. Biol., 9, 800, 10.1016/S0960-9822(99)80363-7 Schulte-Merker, 1997, The zebrafish organizer requires chordino, Nature, 387, 862, 10.1038/43092 Scott, 2001, Homologues of Twisted gastrulation are extracellular cofactors in antagonism of BMP signalling, Nature, 410, 475, 10.1038/35068572 Shih, 1996, Characterizing the zebrafish organizer: microsurgical analysis at the early-shield stage, Development, 122, 1313, 10.1242/dev.122.4.1313 Smith, 1983, Dorsalization and neural induction: properties of the organizer in Xenopus laevis, J. Embryol. Exp. Morphol., 78, 299 Smith, 1992, Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos, Cell, 70, 829, 10.1016/0092-8674(92)90316-5 Smith, 1993, Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm, Nature, 361, 547, 10.1038/361547a0 Smith, 1995, A nodal-related gene defines a physical and functional domain within the Spemann organizer, Cell, 82, 37, 10.1016/0092-8674(95)90050-0 Spemann, 1924, Uber induktion von Embryonalanlagen durch implantation artfremder Organisatoren. Wilhelm Roux', Arch Entwicklungsmech Org, 100, 599 Stern, 2002, Induction and initial patterning of the nervous system - the chick embryo enters the scene, Curr. Opin. Genet. Dev., 12, 447, 10.1016/S0959-437X(02)00324-6 Stern, 2004, Neural induction, 419 Streit, 1998, Chordin regulates primitive streak development and the stability of induced neural cells, but is not sufficient for neural induction in the chick embryo, Development, 125, 507, 10.1242/dev.125.3.507 Streit, 2000, Initiation of neural induction by FGF signalling before gastrulation, Nature, 406, 74, 10.1038/35017617 Suzuki, 1997, Xenopus msx1 mediates epidermal induction and neural inhibition by BMP4, Development, 124, 3037, 10.1242/dev.124.16.3037 Wessely, 2001, Neural induction in the absence of mesoderm: beta-catenin-dependent expression of secreted BMP antagonists at the blastula stage in Xenopus, Dev. Biol., 234, 161, 10.1006/dbio.2001.0258 Whitman, 2001, Nodal signaling in early vertebrate embryos: themes and variations, Dev. Cell, 1, 605, 10.1016/S1534-5807(01)00076-4 Wilson, 2001, Neural induction: toward a unifying mechanism, Nat. Neurosci., 4, 1161, 10.1038/nn747 Wilson, 2000, An early requirement for FGF signalling in the acquisition of neural cell fate in the chick embryo, Curr. Biol., 10, 421, 10.1016/S0960-9822(00)00431-0 Wylie, 1996, Maternal beta-catenin establishes a ‘dorsal signal’ in early Xenopus embryos, Development, 122, 2987, 10.1242/dev.122.10.2987 Xanthos, 2002, The roles of three signaling pathways in the formation and function of the Spemann Organizer, Development, 129, 4027, 10.1242/dev.129.17.4027 Zhang, 1998, The role of maternal VegT in establishing the primary germ layers in Xenopus embryos, Cell, 94, 515, 10.1016/S0092-8674(00)81592-5