Ultrasound-accelerated catheter-directed thrombolysis versus anticoagulation for the prevention of post-thrombotic syndrome (CAVA): a single-blind, multicentre, randomised trial

Browse, 1999, Deep vein thrombosis: pathology, diagnosis and treatment, 443 White, 2003, The epidemiology of venous thromboembolism, Circulation, 107, I4 Kahn, 2008, Determinants and time course of the postthrombotic syndrome after acute deep venous thrombosis, Ann Intern Med, 149, 698, 10.7326/0003-4819-149-10-200811180-00004 Schulman, 2006, Post-thrombotic syndrome, recurrence, and death 10 years after the first episode of venous thromboembolism treated with warfarin for 6 weeks or 6 months, J Thromb Haemost, 4, 734, 10.1111/j.1538-7836.2006.01795.x Kahn, 2008, Determinants of health-related quality of life during the 2 years following deep vein thrombosis, J Thromb Haemost, 6, 1105, 10.1111/j.1538-7836.2008.03002.x Ten Cate-Hoek, 2009, Cost-effectiveness of ruling out deep venous thrombosis in primary care versus care as usual, J Thromb Haemost, 7, 2042, 10.1111/j.1538-7836.2009.03627.x Kearon, 2016, Antithrombotic therapy for VTE disease: CHEST guideline and expert panel report, Chest, 149, 315, 10.1016/j.chest.2015.11.026 Appelen, 2017, Compression therapy for prevention of post-thrombotic syndrome, Cochrane Database Syst Rev, 9 Amin, 2018, Reduced incidence of vein occlusion and postthrombotic syndrome after immediate compression for deep vein thrombosis, Blood, 132, 2298, 10.1182/blood-2018-03-836783 Tick, 2010, Predictors of the post-thrombotic syndrome with non-invasive venous examinations in patients 6 weeks after a first episode of deep vein thrombosis, J Thromb Haemost, 8, 2685, 10.1111/j.1538-7836.2010.04065.x Strijkers, 2015, Validation of the LET classification, Phlebology, 30, 14, 10.1177/0268355515569133 Elsharawy, 2002, Early results of thrombolysis vs anticoagulation in iliofemoral venous thrombosis. A randomised clinical trial, Eur J Vasc Endovasc Surg, 24, 209, 10.1053/ejvs.2002.1665 Comerota, 2007, Treatment of acute iliofemoral deep venous thrombosis: a strategy of thrombus removal, Eur J Vasc Endovasc Surg, 33, 351, 10.1016/j.ejvs.2006.11.013 Enden, 2012, Long-term outcome after additional catheter-directed thrombolysis versus standard treatment for acute iliofemoral deep vein thrombosis (the CaVenT study): a randomised controlled trial, Lancet, 379, 31, 10.1016/S0140-6736(11)61753-4 Haig, 2016, Post-thrombotic syndrome after catheter-directed thrombolysis for deep vein thrombosis (CaVenT): 5-year follow-up results of an open-label, randomised controlled trial, Lancet Haematol, 3, e64, 10.1016/S2352-3026(15)00248-3 Vedantham, 2017, Pharmacomechanical catheter-directed thrombolysis for deep-vein thrombosis, N Engl J Med, 377, 2240, 10.1056/NEJMoa1615066 Comerota, 2019, Endovascular thrombus removal for acute iliofemoral deep vein thrombosis, Circulation, 139, 1162, 10.1161/CIRCULATIONAHA.118.037425 Porter, 1995, Reporting standards in venous disease: an update, J Vasc Surg, 21, 635, 10.1016/S0741-5214(95)70195-8 Villalta, 1994, Assessment of validity and reproducibility of a clinical scale for the post-thrombotic syndrome, Haemostasis, 24, 158a Kahn, 2009, Definition of post-thrombotic syndrome of the leg for use in clinical investigations: a recommendation for standardization, J Thromb Haemost, 7, 879, 10.1111/j.1538-7836.2009.03294.x Rutherford, 2000, Venous severity scoring: an adjunct to venous outcome assessment, J Vasc Surg, 31, 1307, 10.1067/mva.2000.107094 Aaronson, 1998, Translation, validation, and norming of the Dutch language version of the SF-36 health survey in community and chronic disease populations, J Clin Epidemiol, 51, 1055, 10.1016/S0895-4356(98)00097-3 Brooks, 1996, EuroQol: the current state of play, Health Policy, 37, 53, 10.1016/0168-8510(96)00822-6 van der Velden, 2014, Translation and validation of the Dutch VEINES-QOL/Sym in varicose vein patients, Phlebology, 29, 227, 10.1177/0268355513476279 Lamping, 2003, Evaluation of outcomes in chronic venous disorders of the leg: development of a scientifically rigorous, patient-reported measure of symptoms and quality of life, J Vasc Surg, 37, 410, 10.1067/mva.2003.152 Bland, 2015, Validation of the VEINES-QOL quality of life instrument in venous leg ulcers: repeatability and validity study embedded in a randomised clinical trial, BMC Cardiovasc Disord, 15, 85, 10.1186/s12872-015-0080-7 Pollard, 1984, Preliminary validity study of the pain disability index, Percept Mot Skills, 59, 974, 10.2466/pms.1984.59.3.974 Schulman, 2005, Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients, J Thromb Haemost, 3, 692, 10.1111/j.1538-7836.2005.01204.x Prandoni, 2004, Below-knee elastic compression stockings to prevent the post-thrombotic syndrome: a randomized, controlled trial, Ann Intern Med, 141, 249, 10.7326/0003-4819-141-4-200408170-00004 Brandjes, 1997, Randomised trial of effect of compression stockings in patients with symptomatic proximal-vein thrombosis, Lancet, 349, 759, 10.1016/S0140-6736(96)12215-7 Arnoldussen, 2012, An imaging approach to deep vein thrombosis and the lower extremity thrombosis classification, Phlebology, 27, 143, 10.1258/phleb.2012.012s25 Engelberger, 2015, Ultrasound-assisted versus conventional catheter-directed thrombolysis for acute iliofemoral deep vein thrombosis, Circ Cardiovasc Interv, 8, 10.1161/CIRCINTERVENTIONS.114.002027 Prandoni, 1996, The long-term clinical course of acute deep venous thrombosis, Ann Intern Med, 125, 1, 10.7326/0003-4819-125-1-199607010-00001 Prandoni, 2005, Vein abnormalities and the post-thrombotic syndrome, J Thromb Haemost, 3, 401, 10.1111/j.1538-7836.2004.01106.x Bouman, 2016, Clot structure and fibrinolytic potential in patients with post thrombotic syndrome, Thromb Res, 137, 85, 10.1016/j.thromres.2015.11.013 Eijgenraam, 2014, Venous stenting after deep venous thrombosis and antithrombotic therapy: a systematic review, Rev Vasc Med 2, 2, 88, 10.1016/j.rvm.2014.03.001