Nonalcoholic fatty liver disease

Gastroenterology - Tập 122 - Trang 1649-1657 - 2002
Jeanne M. Clark1, Frederick L. Brancati1, Anna Mae Diehl1
1Departments of Medicine and Epidemiology, The Johns Hopkins University, Baltimore, Maryland

Tài liệu tham khảo

Ludwig, 1980, Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease, Mayo Clin Proc, 55, 342 Yano, 2001, Test validity of periodic liver function tests in a population of Japanese male bank employees, J Clin Epidemiol, 54, 945, 10.1016/S0895-4356(01)00355-9 Bellentani, 1994, Prevalence of chronic liver disease in the general population of northern Italy: the Dyonisos study, Hepatology, 20, 1442, 10.1002/hep.1840200611 Bellentani, 2000, Prevalence of and risk factors for hepatic steatosis in Northern Italy, Ann Intern Med, 132, 112, 10.7326/0003-4819-132-2-200001180-00004 Ratziu, 2000, Liver fibrosis in overweight patients, Gastroenterology, 118, 1117, 10.1016/S0016-5085(00)70364-7 Skelly, 2001, Findings on liver biopsy to investigate abnormal liver function tests in the absence of diagnostic serology, J Hepatol, 35, 195, 10.1016/S0168-8278(01)00094-0 Braillon, 1985, Liver in obesity, Gut, 26, 133, 10.1136/gut.26.2.133 Nomura, 1986, Liver function in moderate obesity: study in 534 moderately obese subjects among 4613 male company employees, Int J Obes, 10, 349 Silverman, 1990, Liver pathology in morbidly obese patients with and without diabetes, Am J Gastroenterol, 85, 1345 Adinolfi, 2001, Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity, Hepatology, 33, 1358, 10.1053/jhep.2001.24432 Ong, 2001, Chronic hepatitis C and superimposed nonalcoholic fatty liver disease, Liver, 21, 266, 10.1034/j.1600-0676.2001.021004266.x George, 1998, Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis, Gastroenterology, 114, 311, 10.1016/S0016-5085(98)70482-2 Mendler, 1999, Insulin resistance-associated hepatic iron overload, Gastroenterology, 117, 1155, 10.1016/S0016-5085(99)70401-4 Fargion, 2001, Hyperferritinemia, iron overload, and multiple metabolic alterations identify patients at risk for nonalcoholic steatohepatitis, Am J Gastroenterol, 96, 2448, 10.1111/j.1572-0241.2001.04052.x Graif, 2000, Quantitative estimation of attenuation in ultrasound video images: correlation with histology in diffuse liver disease, Invest Radiol, 35, 319, 10.1097/00004424-200005000-00006 Mendler, 1998, Dual-energy CT in the diagnosis and quantification of fatty liver limited clinical value in comparison to ultrasound scan and single-energy CT, with special reference to iron overload, J Hepatol, 28, 785, 10.1016/S0168-8278(98)80228-6 Ricci, 1997, Noninvasive in vivo quantitative assessment of fat content in human liver, J Hepatol, 27, 108, 10.1016/S0168-8278(97)80288-7 Szczepaniak, 1999, Measurement of intracellular triglyceride stores by H spectroscopy and validation in vivo, Am J Physiol, 276, E977 Bravo, 2001, Liver biopsy, N Engl J Med, 344, 495, 10.1056/NEJM200102153440706 Sheth, 1997, Nonalcoholic steatohepatitis, Ann Intern Med, 126, 137, 10.7326/0003-4819-126-2-199701150-00008 Falck-Ytter, 2001, Clinical features and natural history of nonalcoholic steatosis syndromes, Semin Liver Dis, 21, 71, 10.1055/s-2001-12926 National Center for Statistics, 1994, vol 1 Clark JM, Brancati FL, Diehl AM. Nonalcoholic fatty liver disease and its correlates in the United States. In review. Pratt, 2000, Evaluation of abnormal liver enzyme results in asymptomatic patients, N Engl J Med, 342, 1266, 10.1056/NEJM200004273421707 Bacon, 1994, Nonalcoholic steatohepatitis: an expanded clinical entity, Gastroenterology, 107, 1103, 10.1016/0016-5085(94)90235-6 Powell, 1989, Steatohepatitis associated with limb lipodystrophy, Gastroenterology, 97, 1022, 10.1016/0016-5085(89)91513-8 Giraud, 1997, Excess weight risk factor for alcoholic liver disease, Hepatology, 25, 108, 10.1002/hep.510250120 Cope, 2000, Increased gastrointestinal ethanol production in obese mice: implications for fatty liver disease pathogenesis, Gastroenterology, 119, 1340, 10.1053/gast.2000.19267 Nair, 2001, Obesity and female gender increase breath ethanol concentration: potential implications for the pathogenesis of nonalcoholic steatohepatitis, Am J Gastroenterol, 96, 1200, 10.1111/j.1572-0241.2001.03702.x Rolla, 2000, Detection of circulating antibodies against malondialdehyde-acetaldehyde adducts in patients with alcohol-induced liver disease, Hepatology, 31, 878, 10.1053/he.2000.5373 Hodgson, 1991, Obesity and hepatotoxin risk factors for fatty liver disease, Br J Industr Med, 48, 690 Cotrim, 1999, Nonalcoholic steatohepatitis: a toxic liver disease in industrial workers, Liver, 19, 299, 10.1111/j.1478-3231.1999.tb00053.x Assy, 2000, Fatty infiltration of liver inhyperlipidemic patients, Dig Dis Sci, 45, 1929, 10.1023/A:1005661516165 Cortez-Pinto, 1999, Nonalcoholic fatty liver: another feature of the metabolic syndrome?, Clin Nutr, 18, 10.1016/S0261-5614(99)80015-6 Marceau, 1999, Liver pathology and the metabolic syndrome X in severe obesity, J Clin Endocrinol Metab, 84, 1513, 10.1210/jc.84.5.1513 Marchesini, 1999, Association of nonalcoholic fatty liver disease with insulin resistance, Am J Med, 107, 450, 10.1016/S0002-9343(99)00271-5 Kim, 2001, Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance, Proc Natl Acad Sci U S A, 98, 7522, 10.1073/pnas.121164498 Yuan, 2001, Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IKKbeta, Science, 293, 1673, 10.1126/science.1061620 Kim, 2001, Prevention of fat-induced insulin resistance by salicylate, J Clin Invest, 108, 437, 10.1172/JCI11559 Ni, 2001, Hepatitis B virus infection in children and adolescents in a hyperendemic area: 15 years after mass hepatitis B vaccination, Ann Intern Med, 135, 796, 10.7326/0003-4819-135-9-200111060-00009 Moss, 1991, Cause-specific mortality in a population-based study of diabetes, Am J Public Health, 81, 1158, 10.2105/AJPH.81.9.1158 Alter, 1999, The prevalence of hepatitis C virus infection in the United States: 1988–1994, N Engl J Med, 341, 556, 10.1056/NEJM199908193410802 Nomura, 1988, Prevalence of fatty liver in a general population of Okinawa, Japan, Jpn J Med, 27, 142, 10.2169/internalmedicine1962.27.142 Galambos, 1972, Natural history of alcoholic hepatitis III: histologic changes, Gastroenterology, 56, 515 Pares, 1986, Histologic course of alcoholic hepatitis: influence of abstinence, sex, and extent of hepatic damage, J Hepatol, 2, 33, 10.1016/S0168-8278(86)80006-X Gines, 1987, Compensated cirrhosis: natural history and prognostic factors, Hepatology, 7, 122, 10.1002/hep.1840070124 1993, MMWR Weekly, 41, 969 Poupon, 1999, Combination of steatosis and alcohol intake is the main determinant of fibrosis progression in patients with hepatitis C, Hepatology, 30, 406A Diehl, 1989, Alcohol-like liver disease in nonalcoholics: a clinical and histopathological comparison with alcohol-induced liver injury, Gastroenterology, 95, 1056, 10.1016/0016-5085(88)90183-7 Powell, 1990, The natural history of nonalcoholic steatohepatitis: a follow-up study of 42 patients followed for up to 21 years, Hepatology, 11, 74, 10.1002/hep.1840110114 Matteoni, 1999, Nonalcoholic fatty liver disease: a spectrum of clinical pathological severity, Gastroenterology, 116, 1413, 10.1016/S0016-5085(99)70506-8 Caldwell, 1999, Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease, Hepatology, 29, 664, 10.1002/hep.510290347 Trotter, 2001, Thin chance for fat people (to become living donors), Liver Transpl, 7, 415, 10.1053/jlts.2001.24933 Chamberlain Palmer, 1990, Effect of weight reduction on hepatic abnormalities in overweight patients, Gastroenterology, 99, 1408, 10.1016/0016-5085(90)91169-7 Ueno, 1997, Therapeutic effects of restricted diet and exercise in obese patients with fatty liver, J Hepatol, 27, 103, 10.1016/S0168-8278(97)80287-5 Capron, 1982, Fasting in obesity: another cause of liver injury with alcoholic hyaline?, Dig Dis Sci, 54, 374 Novikoff, 1977, Fatty liver induced in Zucker “fatty” (ff) rats by a semisynthetic diet rich in sucrose, Proc Natl Acad Sci U S A, 74, 3550, 10.1073/pnas.74.8.3550 Poulsom, 1986, Morphological changes of organs after sucrose or fructose feeding, vol. 21, 104 Akiyama, 1996, High-fat hypercaloric diet induces obesity, glucose intolerance and hyperlipidemia in normal adult male Wistar rat, Diabetes Res Clin Pract, 31, 27, 10.1016/0168-8227(96)01205-3 Moller, 1991, Insulin resistance: mechanisms, syndromes, and implications, N Engl J Med, 325, 938, 10.1056/NEJM199109263251307 Lin, 2000, Metformin reverses nonalcoholic fatty liver disease in obese leptin-deficient mice, Nat Med, 6, 998, 10.1038/79697 Kakuma, 2000, Leptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic islets, Proc Natl Acad Sci U S A, 97, 8536, 10.1073/pnas.97.15.8536 Caldwell, 2001, A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis, Am J Gastroenterol, 96, 519, 10.1111/j.1572-0241.2001.03553.x Marchesini, 2001, Metformin in non-alcoholic steatohepatitis, Lancet, 358, 893, 10.1016/S0140-6736(01)06042-1 Kohlroser, 2000, Hepatotoxicity due to troglitazone: report of two cases and review of adverse events reported to the United States Food and Drug Administration, Am J Gastroenterol, 95, 272, 10.1111/j.1572-0241.2000.01707.x Stang, 1999, Incidence of lactic acidosis in metformin users, Diabetes Care, 22, 925, 10.2337/diacare.22.6.925 Shimomura, 1999, Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy, Nature, 401, 73, 10.1038/43448 Newberne, 1969, Effect of two synthetic antioxidants, vitamin E and ascorbic acid, on the choline-deficient rat, J Nutr, 97, 219, 10.1093/jn/97.2.219 de la Maza, 1995, Effects of long-term vitamin E supplementation in alcoholic cirrhotics, J Am Coll Nutr, 14, 192, 10.1080/07315724.1995.10718493 Nanji, 1996, Medium chain triglycerides and vitamin E reduce the severity of established experimental alcoholic liver disease, J Pharmacol Exp Ther, 277, 1694 Lavine, 2000, Vitamin E treatment of non-alcoholic steatohepatitis in children: a pilot study, J Pediatr, 136, 734, 10.1016/S0022-3476(00)05040-X Barak, 1997, The effect of betaine in reversing alcoholic steatosis, Alcohol Clin Exp Res, 21, 1100, 10.1111/j.1530-0277.1997.tb04259.x Abdelmalek, 2001, Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study, Am J Gastroenterol, 96, 2711, 10.1111/j.1572-0241.2001.04129.x Purrello, 1988, Metformin enhances certain insulin actions in cultured rat hepatoma cells, Diabetologia, 31, 385, 10.1007/BF02341508 Solomon, 1997, Pioglitazone and metformin reverse insulin resistance induced by tumor necrosis factor-alpha in liver cells, Horm Metab Res, 29, 379, 10.1055/s-2007-979059 Laurin, 1996, Ursodeoxycholic acid or clofibrate in the treatment of non-alcohol-induced steatohepatitis: a pilot study, Hepatology, 23, 1464, 10.1002/hep.510230624 Basaranoglu, 1999, A controlled trial of gemfibrozil in the treatment of patients with noalcoholic steatohepatitis, J Hepatol, 31, 384, 10.1016/S0168-8278(99)80243-8 Harlander, 2001, Atorvastin for the treatment of NASH, Gastroenterology, 120A, 2767