Identification and Characterization of Prokaryotic Dipeptidyl-peptidase 5 from Porphyromonas gingivalis

Journal of Biological Chemistry - Tập 289 - Trang 5436-5448 - 2014
Yuko Ohara-Nemoto1, Shakh M.A. Rouf1, Mariko Naito2, Amie Yanase1, Fumi Tetsuo1, Toshio Ono1, Takeshi Kobayakawa1, Yu Shimoyama3, Shigenobu Kimura3, Koji Nakayama2, Keitarou Saiki4, Kiyoshi Konishi4, Takayuki K. Nemoto1
1Department of Oral Molecular Biology, Course of Medical and Dental Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588
2Division of Microbiology and Oral Infection, Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588
3Division of Molecular Microbiology, Iwate Medical University, Iwate 028-3694
4Department of Microbiology, Nippon Dental University School of Life Dentistry at Tokyo, Tokyo 102-8159, Japan

Tài liệu tham khảo

Lamont, 1998, Life below the gum line. Pathogenic mechanisms of Porphyromonas gingivalis, Microbiol. Mol. Biol. Rev, 62, 1244, 10.1128/MMBR.62.4.1244-1263.1998 Holt, 2005, Porphyromonas gingivalis Treponema denticola Tanneralla forsythia. The “red complex”, a prototype polybacterial pathogenic consortium in periodontitis, Periodontology 2000, 38, 72, 10.1111/j.1600-0757.2005.00113.x Eke, 2012, Prevalence of periodontitis in adults in the United States, 2009 and 2010, J. Dent. Res, 91, 914, 10.1177/0022034512457373 Iwai, 2005, Oral bacteria in the occluded arteries of patients with Buerger disease, J. Vasc. Surg, 42, 107, 10.1016/j.jvs.2005.03.016 Kshirsagar, 2007, Antibodies to periodontal organisms are associated with decreased kidney function. The Dental atherosclerosis risk in communities study, Blood Purif, 25, 125, 10.1159/000096411 Detert, 2010, The association between rheumatoid arthritis and periodontal disease, Arthritis Res. Ther, 12, 218, 10.1186/ar3106 Takahashi, 2000, Metabolic pathways for cytotoxic end product formation from glutamate- and aspartate-containing peptides by Porphyromonas gingivalis, J. Bacteriol, 182, 4704, 10.1128/JB.182.17.4704-4710.2000 Takahashi, 2001, Preferential utilization of dipeptides by Porphyromonas gingivalis, J. Dent. Res, 80, 1425, 10.1177/00220345010800050801 Nelson, 2003, Complete genome sequence of the oral pathogenic Bacterium Porphyromonas gingivalis strain W83, J. Bacteriol, 185, 5591, 10.1128/JB.185.18.5591-5601.2003 Naito, 2008, Determination of the genome sequence of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalis, DNA Res, 15, 215, 10.1093/dnares/dsn013 Høvik, 2012, Comprehensive transcriptome analysis of the periodontopathogenic bacterium Porphyromonas gingivalis W83, J. Bacteriol, 194, 100, 10.1128/JB.06385-11 Mazumdar, 2009, Metabolic network model of a human oral pathogen, J. Bacteriol, 191, 74, 10.1128/JB.01123-08 Meuric, 2010, Putative respiratory chain of Porphyromonas gingivalis, Future Microbiol, 5, 717, 10.2217/fmb.10.32 Tsuda, 2010, Butyrate, a bacterial metabolite, induces apoptosis and autophagic cell death in gingival epithelial cells, J. Periodont. Res, 45, 626, 10.1111/j.1600-0765.2010.01277.x Niederman, 1997, Short-chain carboxylic acid concentration in human gingival crevicular fluid, J. Dent. Res, 76, 575, 10.1177/00220345970760010801 Pöllänen, 2000, Effect of short chain fatty acids on human gingival epithelial cell keratins in vitro, Eur. J. Oral Sci, 108, 523, 10.1034/j.1600-0722.2000.00881.x Chen, 1992, Purification and characterization of a 50-kDa cysteine proteinase (gingipain) from Porphyromonas gingivalis, J. Biol. Chem, 267, 18896, 10.1016/S0021-9258(19)37045-0 Fujimura, 1992, Comparative studies of three proteases of Porphyromonas gingivalis, Oral Microbiol. Immunol, 7, 212, 10.1111/j.1399-302X.1992.tb00027.x Pike, 1994, Lysine- and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with hemagglutinins, J. Biol. Chem, 269, 406, 10.1016/S0021-9258(17)42365-9 Kadowaki, 1994, Purification and characterization of a novel arginine-specific cysteine proteinase (argingipain) involved in the pathogenesis of periodontal disease from the culture supernatant of Porphyromonas gingivalis, J. Biol. Chem, 269, 21371, 10.1016/S0021-9258(17)31972-5 Banbula, 2000, Emerging family of proline-specific peptidases of Porphyromonas gingivalis. Purification and characterization of serine dipeptidyl peptidase, a structural and functional homologue of mammalian prolyl dipeptidyl peptidase IV, Infect. Immun, 68, 1176, 10.1128/IAI.68.3.1176-1182.2000 Banbula, 2001, Porphyromonas gingivalis DPP-7 represents a novel type of dipeptidylpeptidase, J. Biol. Chem, 276, 6299, 10.1074/jbc.M008789200 Rouf, 2013, Discrimination based on Gly and Arg/Ser at position 673 between dipeptidyl-peptidase (DPP) 7 and DPP11, widely distributed DPPs in pathogenic and environmental Gram-negative bacteria, Biochimie, 95, 824, 10.1016/j.biochi.2012.11.019 Ohara-Nemoto, 2011, Asp- and Glu-specific novel dipeptidyl peptidase 11 of Porphyromonas gingivalis ensures utilization of proteinaceous energy sources, J. Biol. Chem, 286, 38115, 10.1074/jbc.M111.278572 Banbula, 1999, A novel enzyme with possible pathological implications for the development of periodontitis, J. Biol. Chem, 274, 9246, 10.1074/jbc.274.14.9246 Oda, 2009, Participation of the secreted dipeptidyl and tripeptidyl aminopeptidases in asaccharolytic growth of Porphyromonas gingivalis, J. Periodontal Res, 44, 362, 10.1111/j.1600-0765.2008.01117.x Nguyen, 2007, Does the importance of the C-terminal residues in the maturation of RgpB from Porphyromonas gingivalis reveal a novel mechanism for protein export in a subgroup of Gram-negative bacteria?, J. Bacteriol, 189, 833, 10.1128/JB.01530-06 Shi, 1999, Genetic analyses of proteolysis, hemoglobin binding, and hemagglutination of Porphyromonas gingivalis. Construction of mutants with a combination of rgpA rgpB kgp hagA, J. Biol. Chem, 274, 17955, 10.1074/jbc.274.25.17955 Murakami, 2002, Separation of the outer membrane and identification of major outer membrane proteins from Porphyromonas gingivalis, Eur. J. Oral Sci, 110, 157, 10.1034/j.1600-0722.2002.11171.x Lambert, 2002, ESyPred3D. Prediction of proteins 3D structures, Bioinformatics, 18, 1250, 10.1093/bioinformatics/18.9.1250 Shoji, 2010, Characterization of hemin-binding protein 35 (HBP35) in Porphyromonas gingivalis. Its cellular distribution, thioredoxin activity and role in heme utilization, BMC Microbiol, 10, 152, 10.1186/1471-2180-10-152 Nguyen, 2009, Verification of a topology model of PorT as an integral outer-membrane protein in Porphyromonas gingivalis, Microbiology, 155, 328, 10.1099/mic.0.024323-0 Rouf, 2013, Phenylalanine 664 of dipeptidyl peptidase (DPP) 7 and phenylalanine 671 of DPP11 mediate preference for P2-position hydrophobic residues of a substrate, FEBS Open Bio, 3, 177, 10.1016/j.fob.2013.03.004 Suido, 1986, Arylaminopeptidase activities of oral bacteria, J. Dent. Res, 65, 1335, 10.1177/00220345860650111101 Rawlings, 2010, MEROPS. The peptidase database, Nucleic Acids Res, 38, D227, 10.1093/nar/gkp971 Ellis, 1967, Dipeptidyl arylamidase III of the pituitary. Purification and characterization, J. Biol. Chem, 242, 4623, 10.1016/S0021-9258(18)99503-7 Vukelić, 2012, Reactive cysteine in the active-site motif of Bacteroides thetaiotaomicron dipeptidyl peptidase III is a regulatory residue for enzyme activity, Biol. Chem, 393, 37, 10.1515/BC-2011-193 Beauvais, 1997, Biochemical and antigenic characterization of a new dipeptidyl-peptidase isolated from Aspergillus fumigatus, J. Biol. Chem, 272, 6238, 10.1074/jbc.272.10.6238 Pederson, 1998, Improved glucose tolerance in Zucker fatty rats by oral administration of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide, Diabetes, 47, 1253, 10.2337/diab.47.8.1253 Herman, 2006, Pharmacokinetics and pharmacodynamic effects of the oral DPP-4 inhibitor sitagliptin in middle-aged obese subjects, J. Clin. Pharmacol, 46, 876, 10.1177/0091270006289850 Ahrén, 2004, Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces glucagon levels in type 2 diabetes, J. Clin. Endocrinol. Metab, 89, 2078, 10.1210/jc.2003-031907 Monod, 2013, Dipeptidyl-peptidases IV and V of Aspergillus, 3392 Monera, 1995, Relationship of side chain hydrophobicity and α-helical propensity on the stability of the single-stranded amphipathic α-helix, J. Pept. Sci, 1, 319, 10.1002/psc.310010507 Nakajima, 2008, Dipeptidyl aminopeptidase IV from Stenotrophomonas maltophilia exhibits activity against a substrate containing a 4-hydroxyproline residue, J. Bacteriol, 190, 7819, 10.1128/JB.02010-07 Vermout, 2008, Secreted dipeptidyl peptidases as potential virulence factors for Microsporum canis, FEMS Immunol. Med. Microbiol, 54, 299, 10.1111/j.1574-695X.2008.00479.x Sato, 2010, A protein secretion system linked to bacteroidete gliding motility and pathogenesis, Proc. Natl. Acad. Sci. U.S.A, 107, 276, 10.1073/pnas.0912010107 Rosenblum, 2003, Prolyl peptidases. A serine protease subfamily with high potential for drug discovery, Curr. Opin. Chem. Biol, 7, 496, 10.1016/S1367-5931(03)00084-X Rasmussen, 2003, Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog, Nat. Struct. Biol, 10, 19, 10.1038/nsb882