Drug-Loaded Nanoparticles Targeted to the Colon With Polysaccharide Hydrogel Reduce Colitis in a Mouse Model

Gastroenterology - Tập 138 - Trang 843-853.e2 - 2010
Hamed Laroui1, Guillaume Dalmasso1, Hang Thi Thu Nguyen1, Yutao Yan1, Shanthi V. Sitaraman1, Didier Merlin1
1Division of Digestive Diseases, Department of Medicine, Emory University, Atlanta, Georgia

Tài liệu tham khảo

Ballinger, 2008, Adverse effects of nonsteroidal anti-inflammatory drugs on the colon, Curr Gastroenterol Rep, 10, 485, 10.1007/s11894-008-0089-5 Langan, 2007, Ulcerative colitis: diagnosis and treatment, Am Fam Physician, 76, 1323 Truelove, 1960, Systemic and local corticosteroid therapy in ulcerative colitis, Br Med J, 1, 464, 10.1136/bmj.1.5171.464 Reshef, 1992, Systemic effects of rectally administered corticosteroids, Isr J Med Sci, 28, 98 Hebrard, 2009, Investigation of coated whey protein/alginate beads as sustained release dosage form in simulated gastrointestinal environment, Drug Dev Ind Pharm, 14, 1 Lamprecht, 2005, A pH-sensitive microsphere system for the colon delivery of tacrolimus containing nanoparticles, J Control Release, 104, 337, 10.1016/j.jconrel.2005.02.011 Lamprecht, 2005, Nanoparticles enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats, J Pharmacol Exp Ther, 315, 196, 10.1124/jpet.105.088146 Leserman, 1981, Cell-specific drug transfer from liposomes bearing monoclonal antibodies, Nature, 293, 226, 10.1038/293226a0 Laroui, 2007, Hyaluronate-covered nanoparticles for the therapeutic targeting of cartilage, Biomacromolecules, 8, 3879, 10.1021/bm700836y Makhlof, 2009, pH-sensitive nanospheres for colon-specific drug delivery in experimentally induced colitis rat model, Eur J Pharm Biopharm, 72, 1, 10.1016/j.ejpb.2008.12.013 Meissner, 2006, Nanoparticles in inflammatory bowel disease: particle targeting versus pH-sensitive delivery, Int J Pharm, 316, 138, 10.1016/j.ijpharm.2006.01.032 Feng, 2009, Poly(lactide)-vitamin E derivative/montmorillonite nanoparticle formulations for the oral delivery of Docetaxel, Biomaterials, 30, 3297, 10.1016/j.biomaterials.2009.02.045 Yang, 2009, Poly(D,L-lactide-co-glycolide) nanoparticles encapsulated fluorescent isothiocyanate and paclitaxol: preparation, release kinetics and anticancer effect, J Nanosci Nanotechnol, 9, 282, 10.1166/jnn.2009.J065 Fukui, 1987, Studies on the promoting effect of lipid-surfactant mixed micelles (MM) on intestinal absorption of colloidal particles, J Pharmacobiodyn, 10, 236, 10.1248/bpb1978.10.236 Kitajima, 1999, Changes in colonic mucosal permeability in mouse colitis induced with dextran sulfate sodium, Exp Anim, 48, 137, 10.1538/expanim.48.137 Lamprecht, 2001, Size-dependent bioadhesion of micro- and nanoparticulate carriers to the inflamed colonic mucosa, Pharm Res, 18, 788, 10.1023/A:1011032328064 Bachmanov, 2002, Food intake, water intake, and drinking spout side preference of 28 mouse strains, Behav Genet, 32, 435, 10.1023/A:1020884312053 Dalmasso, 2008, PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation, Gastroenterology, 134, 166, 10.1053/j.gastro.2007.10.026 Brzoska, 2008, Alpha-melanocyte-stimulating hormone and related tripeptides: biochemistry, antiinflammatory and protective effects in vitro and in vivo, and future perspectives for the treatment of immune-mediated inflammatory diseases, Endocr Rev, 29, 581, 10.1210/er.2007-0027 Kannengiesser, 2008, Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease, Inflamm Bowel Dis, 14, 324, 10.1002/ibd.20334 Burd, 1991, Hyaluronan and wound healing: a new perspective, Br J Plast Surg, 44, 579, 10.1016/0007-1226(91)90093-Y Yotsuyanagi, 1987, Calcium-induced gelation of alginic acid and pH-sensitive reswelling of dried gels, Chem Pharm Bull, 35, 1555, 10.1248/cpb.35.1555 Garcia, 1996, Preliminary spherical agglomerates of water soluble drug using natural polymer and cross-linked technique, J Control Release, 40, 179, 10.1016/0168-3659(95)00179-4 Clayton, 1991, The effect of capsule composition on the biocompatibility of alginate-poly-l-lysine capsules, J Microencapsul, 8, 221, 10.3109/02652049109071490 Azab, 2006, Crosslinked chitosan implants as potential degradable devices for brachytherapy: in vitro and in vivo analysis, J Control Release, 111, 281, 10.1016/j.jconrel.2005.12.014 Tozaki, 2002, Chitosan capsules for colon-specific drug delivery: enhanced localization of 5-aminosalicylic acid in the large intestine accelerates healing of TNBS-induced colitis in rats, J Control Release, 82, 51, 10.1016/S0168-3659(02)00084-6 Mladenovska, 2007, Colon-specific delivery of 5-aminosalicylic acid from chitosan-Ca-alginate microparticles, Int J Pharm, 342, 124, 10.1016/j.ijpharm.2007.05.028 Shi, 2006, Therapeutic potential of chitosan and its derivatives in regenerative medicine, J Surg Res, 133, 185, 10.1016/j.jss.2005.12.013 Xiao, 2005, Assessment of cytotoxicity by emerging impedance spectroscopy, Toxicol Appl Pharmacol, 206, 102, 10.1016/j.taap.2004.10.025 Jain, 2005, The role of nanobiotechnology in drug discovery, Drug Discov Today, 10, 1435, 10.1016/S1359-6446(05)03573-7 Lamprecht, 2003, Multiparticulate systems in the treatment of inflammatory bowel disease, Curr Drug Targets Inflamm Allergy, 2, 137, 10.2174/1568010033484188 Bertholon, 2006, Bioadhesive properties of poly(alkylcyanoacrylate) nanoparticles coated with polysaccharide, J Nanosci Nanotechnol, 6, 3102, 10.1166/jnn.2006.418 Hillaireau, 2007, Encapsulation of mono- and oligo-nucleotides into aqueous-core nanocapsules in presence of various water-soluble polymers, Int J Pharm, 331, 148, 10.1016/j.ijpharm.2006.10.031 Nugent, 2001, Intestinal luminal pH in inflammatory bowel disease: possible determinants and implications for therapy with aminosalicylates and other drugs, Gut, 48, 571, 10.1136/gut.48.4.571 Luger, 2003, New insights into the functions of alpha-MSH and related peptides in the immune system, Ann N Y Acad Sci, 994, 133, 10.1111/j.1749-6632.2003.tb03172.x Sogias, 2008, Why is chitosan mucoadhesive?, Biomacromolecules, 9, 1837, 10.1021/bm800276d Laroui, 2007, Hyaluronate-covered nanoparticles for the therapeutic targeting of cartilage, Biomacromolecules, 8, 3879, 10.1021/bm700836y Ngamwongsatit, 2008, WST-1-based cell cytotoxicity assay as a substitute for MTT-based assay for rapid detection of toxigenic Bacillus species using CHO cell line, J Microbiol Methods, 73, 211, 10.1016/j.mimet.2008.03.002 Charrier, 2005, ADAM-15 inhibits wound healing in human intestinal epithelial cell monolayers, Am J Physiol Gastrointest Liver Physiol, 288, G346, 10.1152/ajpgi.00262.2004