The Relation of Dosing to Clopidogrel Responsiveness and the Incidence of High Post-Treatment Platelet Aggregation in Patients Undergoing Coronary Stenting

Journal of the American College of Cardiology - Tập 45 - Trang 1392-1396 - 2005
Paul A. Gurbel1, Kevin P. Bliden1, Kevin M. Hayes1, Jason A. Yoho1, William R. Herzog1, Udaya S. Tantry1
1Sinai Center for Thrombosis Research, Baltimore, Maryland.

Tài liệu tham khảo

Gurbel, 2003, Clopidogrel for coronary stenting, Circulation, 107, 2908, 10.1161/01.CIR.0000072771.11429.83 Jaremo, 2002, Individual variations of platelet inhibition after loading doses of clopidogrel, J Intern Med, 252, 233, 10.1046/j.1365-2796.2002.01027.x Muller, 2003, Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement, Thromb Haemost, 89, 783, 10.1055/s-0037-1613462 Matetzky, 2004, Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction, Circulation, 109, 3171, 10.1161/01.CIR.0000130846.46168.03 Gurbel, 2004, Clopidogrel response variability and resistance, Haematologica, 89, 9 Lau, 2004, Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance, Circulation, 109, 166, 10.1161/01.CIR.0000112378.09325.F9 Taubert, 2004, Pharmacokinetics of clopidogrel after administration of a high loading dose, Thromb Haemost, 92, 311, 10.1160/TH04-02-0105 Muller, 2001, Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement, Heart, 85, 92, 10.1136/heart.85.1.92 Angiolillo, 2004, High clopidogrel loading dose during coronary stenting, Eur Heart J, 25, 1903, 10.1016/j.ehj.2004.07.036 Kastrati, 2004, Loading with 600 mg clopidogrel in patients with coronary artery disease with and without chronic clopidogrel therapy, Circulation, 110, 1916, 10.1161/01.CIR.0000137972.74120.12 Gurbel, 2004, Failure of clopidogrel to reduce platelet reactivity and activation following standard dosing in elective stenting, Platelets, 15, 95, 10.1080/09537100310001646950 Barragan, 2003, Resistance to thienopyridines, Catheter Cardiovasc Interv, 59, 295, 10.1002/ccd.10497 Bliden, 2005, High platelet reactivity is a risk factor for post-discharge ischemic complications following elective coronary stenting, J Am Coll Cardiol, 45, 33A Gurbel, 2005, The Clopidogrel Resistance and Stent Thrombosis (CREST) study, J Am Coll Cardiol, 45, 34A Gurbel, 2003, The early antiplatelet effects of clopidogrel loading for coronary stenting and the long-term stability of inhibition, J Thromb Haemost, 1, 1319, 10.1046/j.1538-7836.2003.00184.x Gurbel, 2003, A new method of representing drug-induced platelet inhibition, Platelets, 14, 481, 10.1080/02697450310001632588 Cutlip, 2001, Stent thrombosis in the modern era, Circulation, 103, 1967, 10.1161/01.CIR.103.15.1967 Samara, 2005, The difference between clopidogrel responsiveness and post-treatment platelet reactivity, Thromb Res, 115, 89, 10.1016/j.thromres.2004.07.002