Anglo-Saxon pharmacopoeia revisited: a potential treasure in drug discovery

Drug Discovery Today - Tập 16 - Trang 1069-1075 - 2011
Frances Watkins1, Barbara Pendry1, Olivia Corcoran1, Alberto Sanchez-Medina1
1Medicines Research Group, School of Health and Bioscience, University of East London, Romford Road, London E15 4LZ, UK

Tài liệu tham khảo

Cameron, 2008, The sources of medical knowledge in Anglo-Saxon England, Anglo-Saxon Engl., 11, 135, 10.1017/S0263675100002593 De Vos, 2010, European materia medica in historical texts: longevity of a tradition and implications for future use, J. Ethnopharmacol., 132, 28, 10.1016/j.jep.2010.05.035 Whitelock, 1961 Pettit, 2001 Voigts, 1979, Anglo-Saxon plant remedies and the Anglo-Saxons, ISIS, 70, 250, 10.1086/352199 Meaney, 1984, Variant versions of Old English Medieval Remedies and the compilation of Bald's Leechbook, Anglo-Saxon Engl., 13, 235, 10.1017/S0263675100003604 Cameron, 2006 Pollington, 2008 Cockayne, 1864 Meaney, 2000, The practice of medicine in England about the year 1000, Social Hist. Med., 13, 221, 10.1093/shm/13.2.221 Hagen, 2006 Van Arsdall, 2002 Hunt, 1989 Borchardt, 2008, Antimicrobial activity of native and naturalized plants of Minnesota and Wisconsin, J. Med. Plants Res., 2, 98 Francis, 2008, Chemiluminescence detection of opium poppy (Papaver somniferum) alkaloids, J. Pharm. Biomed. Anal., 48, 508, 10.1016/j.jpba.2008.06.022 Holland, 1996 Fazio, 2009, Tolerance, safety and efficacy of Hedera helix extract in inflammatory bronchial disease under clinical practice conditions: a prospective, open, multicentre postmarketing study in 9657 patients, Phytomedicine, 16, 17, 10.1016/j.phymed.2006.05.003 2000 Benedek, 2007, Achillea millefolium L S.I.–is the anti-inflammatory activity mediated by protease inhibition?, J. Ethnopharmacol., 113, 312, 10.1016/j.jep.2007.06.014 Burk, 2010, Aqueous extract of Achillea millefolium L. (Asteraceae) inflorescences suppresses lipopolysaccharide-induced inflammatory responses in RAW 264.7 murine macrophages, J. Med. Plants Res., 4, 225 Santos, 2010, Antileishmanial activity of an essential oil from the leaves and flowers of Achillea millefolium, Ann. Trop. Med. Parasitol., 104, 475, 10.1179/136485910X12786389891281 Pires, 2009, Antinociceptive peripheral effect of Achillea millefolium L and Artemesia vulgaris L.: both plants known popularly by brand names of analgesic drugs, Phytother. Res., 23, 212, 10.1002/ptr.2589 Ramadan, 2006, Chamazulene carboxylic acid and matricin: a natural profen and its natural prodrug, identified through similarity to synthetic drug substances, J. Nat. Prod., 69, 1041, 10.1021/np0601556 Imming, 2007, Synthesis of derivates of chamazulene carboxylic acid as potential inhibitors of inflammation via interaction with CB receptors, Planta Med., 73, 829 Choudhary, 2009, Antiinflammatory and lipoxygenase inhibitory compounds from Vitex agnus-castus, Phytother. Res., 23, 1336, 10.1002/ptr.2639 Haïdara, 2006, The flavonoid casticin has multiple mechanisms of tumor cytotoxicity action, Cancer Lett., 242, 180, 10.1016/j.canlet.2005.11.017 Quave, 2009, Anti-biofilm activity of Marrubium vulgare L (Lamiaceae) extract on MRSA, Planta Med., 75, 451, 10.1055/s-2009-1216534 Meyre-Silva, 2005, Analgesic potential of marrubiin derivatives, a bioactive diterpene present in Marrubium vulgare (Lamiaceae), Il Farmaco., 60, 321, 10.1016/j.farmac.2005.01.003 Nicholas, 1964, Isolation of marrubiin, a sterol, and a sesquiterpene from Marrubium vulgare, J. Pharm. Sc., 53, 895, 10.1002/jps.2600530810 Stulzer, 2006, Antioedematogenic effect of marrubiin obtained from Marrubium vulgare, J. Ethnopharmacol., 108, 379, 10.1016/j.jep.2006.05.023 El Bardai, 2004, Marrubenol interacts with the phenylalkylamine binding site of the L-type calcium channel, Eur. J. Pharmacol., 492, 269, 10.1016/j.ejphar.2004.04.007 Tas, 2003, The effects of sildenafil citrate (Viagra) in the early phase of healing process in open wounds in dogs, Acta Vet. Brno, 72, 273, 10.2754/avb200372020273 Alkhatib, 2010, Activity of ladanein on leukaemia cell lines and its occurrence in Marrubium vulgare, Plant Med., 76, 86, 10.1055/s-0029-1185972 Gupta, 2010, Integrated ligand and structure based studies of flavonoids as fatty acid biosynthesis inhibitors of Plasmodium falciparum, Bioorg. Med. Chem. Lett., 20, 4779, 10.1016/j.bmcl.2010.06.120 Pardo, 1993, Isolation of verbascoside, an antimicrobial constituent of Buddleja globosa leaves, J. Ethnopharmacol., 39, 221, 10.1016/0378-8741(93)90041-3 Rigano, 2006, Phenolic compounds of Marrubium globosum ssp libanoticum from Lebanon, Biochem. Syst. Ecol., 34, 256, 10.1016/j.bse.2005.10.006 Grieve, 1992 Saddiqe, 2010, A review of the antibacterial activity of Hypericum perforatum L, J. Ethnopharmacol., 131, 511, 10.1016/j.jep.2010.07.034 Suntar, 2010, Investigations on the in vivo wound healing potential of Hypericum perforatum L, J. Ethnopharmacol., 127, 468, 10.1016/j.jep.2009.10.011 Öztürk, 2007, Wound-healing activity of St. John's Wort (Hypericum perforatum L.) on chicken embryonic fibroblasts, J. Ethnopharmacol., 111, 33, 10.1016/j.jep.2006.10.029 Tawaha, 2010, Determination of hypericin and hyperforin content in selected Jordanian Hypericum species, Ind. Crops Prod., 32, 241, 10.1016/j.indcrop.2010.04.017 Agostinis, 2002, Hypericin in cancer treatment: more light on the way, Int. J. Biochem. Cell Biol., 34, 221, 10.1016/S1357-2725(01)00126-1 Helgason, 2000, The effects of St. John's Wort (Hypericum perforatum) on NK cell activity in vitro, Immunopharmacology, 46, 247, 10.1016/S0162-3109(99)00187-3 Galeotti, 2010, St. John's Wort reduces neuropathic pain through a hypericin-mediated inhibition of the protein kinase C gamma and epsilon activity, Biochem. Pharmacol., 79, 1327, 10.1016/j.bcp.2009.12.016 Rodríguez-Landa, 2003, A review of clinical and experimental observations about antidepressant actions and side effects produced by Hypericum perforatum extracts, Phytomedicine, 10, 688, 10.1078/0944-7113-00340 Mennini, 2004, The antidepressant mechanism of Hypericum perforatum, Life Sci., 75, 1021, 10.1016/j.lfs.2004.04.005 Hart, 2003 Buenz, 2004, Techniques: bioprospecting historical herbal texts by hunting for new leads in old tomes, Trends Pharmacol. Sci., 25, 494, 10.1016/j.tips.2004.07.003 Culpeper, 1995 James, 2009 Funes, 2010, Effects of verbascoside, a phenylpropanoid glycoside from lemon verbena, on phospholipid model membranes, Chem. Phys. Lipids., 163, 190, 10.1016/j.chemphyslip.2009.11.004 Marioni, 2008, A straightforward procedure to biosynthesise melatonin using freshly chopped Achillea millefolium L as reagent, Chem. Lett., 1, 107 Corcoran, 2003, LC–NMR-MS in drug discovery, Drug Discov. Today, 8, 624, 10.1016/S1359-6446(03)02749-1 Gao, 2010, Secondary metabolic mapping identifies Scutellaria inhibitors of human lung cancer cells, J. Pharm. Biomed. Anal., 53, 723, 10.1016/j.jpba.2010.04.019 Kumer, 2010, Reinvestigation of structure–activity relationship of methoxylated chalcones as antimalarials: synthesis and evaluation of 2,4,5-trimethoxy substituted patterns as lead candidates derived from abundantly available natural beta-asarone, Eur. J. Med. Chem., 45, 5292, 10.1016/j.ejmech.2010.08.049 Shah, 2010, Bronchodilatory effect of Acorus calamus (Linn.) is mediated through multiple pathways, J. Ethnopharmacol., 131, 471, 10.1016/j.jep.2010.07.024 Kaminskyy, 2006, Correlation of the cytotoxic activity of four different alkaloids, from Chellidonium majus (greater celandine), with their DNA intercalating properties and ability to induce breaks in the DNA of NK/Ly murine lymphoma cells, Cent. Eur. J. Biol., 1, 2, 10.2478/s11535-006-0001-y Hillier, 1998, Antispasmodic and relaxant activity of chelidonine, protopine, coptisine, and Chelidonium majus extracts on isolated guinea-pig ileum, Planta Med., 64, 758, 10.1055/s-2006-957576 Yang, 2010, Oral colchicines (Colcrys): in the treatment and prophylaxis of gout, Drugs, 70, 1603, 10.2165/11205470-000000000-00000 Edwards, 2011, Tubulin-binding dibenz [c,e] oxepines as cochinol analogues for targeting tumour vasculature, Org. Biomol. Chem., 9, 219, 10.1039/C0OB00500B Haas, 1995, Hyoscymus niger (henbane), J. Neurol. Neurosur. Psychiatr., 59, 114, 10.1136/jnnp.59.2.114 Begum, 2010, Study of anti-inflammatory, analgesic and antipyretic activities of seeds of Hyoscymus niger and isolation of a new coumarinolignan, Fitoterapia, 81, 178, 10.1016/j.fitote.2009.08.024 Brattstrom, 2010, The plant extract Isatis tinctoria L extract (ITE) inhibits allergen-induced airway inflammation and hyperactivity in mice, Phytomedicine, 17, 551, 10.1016/j.phymed.2009.11.003 Mohn, 2009, A comprehensive metabolite profiling of Isatis tinctoria leaf extracts, Phytochemistry, 70, 924, 10.1016/j.phytochem.2009.04.019 Samuelsen, 2000, The traditional uses, chemical constituents and biological activities of Plantago major L. A review, J. Ethnopharmacol., 71, 1, 10.1016/S0378-8741(00)00212-9 Suntar, 2010, Wound healing potential of Sambucus ebulus L. leaves and isolation of an active component, quercetin 3-O-glucoside, J. Ethnopharmacol., 129, 106, 10.1016/j.jep.2010.01.051 Pieri, 2009, Iridoid glycosides from the leaves of Sambucus ebulus, J. Nat. Prod., 72, 1798, 10.1021/np900373u Citores, 2002, Targeting cancer cells with transferrin conjugates containing the non-toxic type 2 ribosome-inactivating proteins nigrin b or ebulin I, Cancer Lett., 184, 29, 10.1016/S0304-3835(02)00169-6 British Herbal Medicine Association, 1996 Alternative Medicine Review, 2002, Isatis tinctoria (Monograph), Altern. Med. Rev., 7, 523 Shorkrzadeh, 2010, The chemistry, pharmacology and clinical properties of Sambucus ebulus: a review, J. Med. Plant. Res., 4, 95