Glucocorticoid receptors: ATP-dependent cycling and hormone-dependent hyperphosphorylation

Munck, 1967, Specific metabolic and physicochemical interactions of glucocorticoids in vivo and in vitro with rat adipose tissue and thymus cells, Excerpta Med. Int. Cong. Ser., 132, 472 Munck, 1968, Specific and nonspecific physicochemical interactions of glucocorticoids and related steroids with rat thymus cells in vitro, J. Biol. Chem., 243, 5556, 10.1016/S0021-9258(18)91904-6 Bell, 1973, Steroid-binding properties and stabilization of cytoplasmic glucocorticoid receptors from rat thymus cells, Biochem. J., 136, 97, 10.1042/bj1360097 Munck, 1972, Glucocorticoid-receptor complexes and the earliest steps in the action of glucocorticoids on thymus cells, J. Steroid Biochem., 3, 567, 10.1016/0022-4731(72)90103-3 Jensen, 1972, Estrophile to nucleophile in two easy steps, J. Steroid Biochem., 3, 445, 10.1016/0022-4731(72)90091-X Munck, 1979, Activation of steroid hormone-receptor complexes in intact target cells in physiological conditions, Nature, 278, 752, 10.1038/278752a0 Wira, 1974, Glucocorticoid-receptor complexes in rat thymus cells. “Cytoplasmic”-nuclear transformations, J. Biol. Chem., 249, 5328, 10.1016/S0021-9258(19)42368-5 Samuels, 1970, Relation of steroid structure to enzyme induction in hepatoma tissue culture cells, J. Molec. Biol., 52, 57, 10.1016/0022-2836(70)90177-4 Rousseau, 1972, Glucocorticoid receptors: relations between steroid binding and biological effects, J. Molec. Biol., 67, 99, 10.1016/0022-2836(72)90389-0 Housley, 1983, Direct demonstration of glucocorticoid receptor phosphorylation by intact L-cells, J. Biol. Chem., 258, 4630, 10.1016/S0021-9258(18)32670-X Mendel, 1987, Activation of cytosolic glucocorticoid-receptor complexes in intact WEHI-7 cells does not dephosphorylate the steroid-binding protein, J. Biol. Chem., 262, 5644, 10.1016/S0021-9258(18)45622-0 Ortí, 1989, Agonist-dependent phosphorylation and nuclear dephosphorylation of glucocorticoid receptors in intact cells, J. Biol. Chem., 264, 9728, 10.1016/S0021-9258(18)81715-X Hoeck, 1989, Down-regulation and phosphorylation of glucocorticoid receptors in cultured cells. Investigations with a monospecific antiserum against a bacterially expressed receptor fragment, J. Biol. Chem., 264, 14396, 10.1016/S0021-9258(18)71692-X Höck, 1989, Regulation of glucocorticoid receptor activity, J. Steroid Biochem., 34, 71, 10.1016/0022-4731(89)90067-8 Hoeck, 1990, Hormone-dependent phosphorylation of the glucocorticoid receptor occurs mainly in the amino-terminal transactivation domain, J. Biol. Chem., 265, 5403, 10.1016/S0021-9258(19)39373-1 Ortí, 1993, Kinetics of glucocorticoid receptor phosphorylation in intact cells. Evidence for hormone-induced hyperphosphorylation after activation and recycling of hyperphosphorylated receptors, J. Biol. Chem., 268, 7779, 10.1016/S0021-9258(18)53026-X Ortí, 1992, Phosphorylation of steroid hormone receptors, Endocrine Rev., 13, 105 Hirst, 1990, High level expression of wild type and variant mouse glucocorticoid receptors in chinese hamster ovary cells, Molec. Endocr., 4, 162, 10.1210/mend-4-1-162 Bodwell, 1991, Identification of phosphorylated sites in the mouse glucocorticoid receptor, J. Biol. Chem., 266, 7549, 10.1016/S0021-9258(20)89482-4 Denner, 1990, Hormonal regulation and identification of chicken progesterone receptor phosphorylation sites, J. Biol. Chem., 265, 16548, 10.1016/S0021-9258(17)46258-2 Ali, 1993, Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region, EMBO J, 12, 1153, 10.1002/j.1460-2075.1993.tb05756.x Mendel, 1986, Glucocorticoid receptors lacking hormone-binding activity are bound in nuclei of ATP-depleted cells, Nature, 324, 478, 10.1038/324478a0 Mendel, 1986, Molybdate-stabilized nonactivated glucocorticoid-receptor complexes contain a 90-kDa non-steroid-binding phosphoprotein that is lost on activation, J. Biol. Chem., 261, 3758, 10.1016/S0021-9258(17)35712-5 Mendel, 1988, Isoform composition and stoichiometry of the ∼90-kDa heat shock protein associated with glucocorticoid receptors, J. Biol. Chem., 263, 6695, 10.1016/S0021-9258(18)68698-3 Scherrer, 1992, A heat shock protein complex isolated from rabbit reticulocyte lysate can reconstitute a functional glucocorticoid receptor-Hsp90 complex, Biochemistry, 31, 7325, 10.1021/bi00147a017 von Hippel, 1989, Facilitated target location in biological systems, J. Biol. Chem., 264, 675, 10.1016/S0021-9258(19)84994-3 Raaka, 1983, The glucocorticoid receptor in GH1 cells: evidence from dense amino acid labeling and whole cell studies for an equilibrium model explaining the influence of hormone on the intracellular distribution of receptor, J. Biol. Chem., 258, 417, 10.1016/S0021-9258(18)33272-1 Distelhorst, 1989, Kinetic pulse-chase labeling study of the glucocorticoid receptor in mouse lymphoma cells. Effect of glucocorticoid and antiglucocorticoid hormones on intracellular receptor half-life, J. Biol. Chem., 264, 13080, 10.1016/S0021-9258(18)51598-2 Munck, 1984, Glucocorticoid-receptor complexes in rat thymus cells: Rapid kinetic behavior and a cyclic model, J. Biol. Chem., 259, 820, 10.1016/S0021-9258(17)43531-9 Housley, 1984, Inactivation, activation, and stabilization of glucocorticoid receptors, Biochem. Actions Horm., 11, 347, 10.1016/B978-0-12-452811-6.50017-7 Sanchez, 1985, Evidence that the 90-kDa phosphoprotein associated with the untransformed L-cell glucocorticoid receptor is a murine heat shock protein, J. Biol. Chem., 260, 12398, 10.1016/S0021-9258(17)38886-5 Bresnick, 1989, Evidence that the 90-kDa heat shock protein is necessary for the steroid binding conformation of the L cell glucocorticoid receptor, J. Biol. Chem., 264, 4992, 10.1016/S0021-9258(18)83689-4 Scherrer, 1990, Structural and functional reconstitution of the glucocorticoid receptor-Hsp90 complex, J. Biol. Chem., 265, 21397, 10.1016/S0021-9258(18)45746-8 Hutchison, 1992, Monovalent cation selectivity for ATP-dependent association of the glucocorticoid receptor with hsp70 and hsp90, J. Biol. Chem., 267, 14047, 10.1016/S0021-9258(19)49676-2 Danielson, 1987, Domains of the glucocorticoid receptor involved in specific and nonspecific deoxyribonucleic acid binding, hormone activation, and transcriptional enhancement, Molec. Endocr., 1, 816, 10.1210/mend-1-11-816 Madan, 1993, Bidirectional transport of glucocorticoid receptors across the nuclear envelope, 90, 3588 Smith, 1990, Reconstitution of progesterone receptor with heat shock proteins, Molec. Endocr., 4, 1704, 10.1210/mend-4-11-1704 Smith, 1992, Assembly of progesterone receptor with heat shock proteins and receptor activation are ATP mediated events, J. Biol. Chem., 267, 1350, 10.1016/S0021-9258(18)48438-4 Mendel, 1990, Evidence for a glucocorticoid receptor cycle and nuclear dephosphorylation of the steroid-binding protein, 97 Ortí, 1989, A dynamic model for glucocorticoid receptor phosphorylation and cycling in intact cells, J. Steroid Biochem., 34, 85, 10.1016/0022-4731(89)90069-1 Berezney, 1991, The nuclear matrix: a heuristic model for investigating genomic organization and function in the cell nucleus, J. Cell Biol., 47, 109 Norbury, 1992, Animal cell cycles and their control, A. Rev. Biochem., 61, 441, 10.1146/annurev.bi.61.070192.002301 Griffin, 1969, Cell cycle events in the hydrocortisone regulation of alkaline phosphatase in HeLa S3 cells, J. Cell Biol., 40, 297, 10.1083/jcb.40.2.297 Tomkins, 1969, Control of specific gene expression in higher organisms, Science, 166, 1474, 10.1126/science.166.3912.1474 Martin, 1969, Synthesis and induction of tyrosine aminotransferase in synchronized hepatoma cells in culture, 62, 248 Fanger, 1986, Regulation of epidermal growth factor receptors by glucocorticoids during the cell cycle in HeLa S3 cells, Archs Biochem. Biophys., 249, 116, 10.1016/0003-9861(86)90566-7 Hsu, 1992, Cell cycle regulation of glucocorticoid receptor function, EMBO Jl, 11, 3457, 10.1002/j.1460-2075.1992.tb05425.x Cidlowski, 1977, Alteration in glucocorticoid binding site number during the cell cycle in HeLa cells, Nature, 266, 643, 10.1038/266643a0 Distelhorst, 1984, Effect of cell cycle position on dexamethasone binding by mouse and human lymphoid cell lines: correlation between an increase in dexamethasone binding during S phase and dexamethasone sensitivity, Blood, 63, 105, 10.1182/blood.V63.1.105.105 Cidlowski, 1982, Glucocorticoid receptors and the cell cycle: evidence that the accumulation of glucocorticoid receptors during the S phase of the cell cycle is dependent on ribonucleic acid and protein synthesis, Endocrinology, 110, 1653, 10.1210/endo-110-5-1653 Currie, 1982, Identification of modified forms of human glucocorticoid receptors during the cell cycle, Endocrinology, 110, 2192, 10.1210/endo-110-6-2192 Currie, 1983, Physiological regulation of steroid hormone action, 465