The Diagnosis, Management, and Postnatal Prevention of Intraventricular Hemorrhage in the Preterm Neonate

McCormick, 1990, Very low birth weight children: behavior problems and school difficulty in a national sample, J Pediatr, 117, 687, 10.1016/S0022-3476(05)83322-0 Whitaker, 1996, Neonatal cranial ultrasound abnormalities in low birth weight infants: Relation to cognitive outcomes at six years of age, Pediatrics, 98, 719, 10.1542/peds.98.4.719 Anderson, 1999, Modeling analysis of change of neurologic abnormalities in children born prematurely: a novel approach, J Child Neurol, 14, 502, 10.1177/088307389901400804 Hansen, 2002, Intelligence in preterm children at four years of age as a predictor of school function: a longitudinal controlled study, Dev Med Child Neurol, 44, 517, 10.1111/j.1469-8749.2002.tb00322.x Koller, 1997, Patterns of cognitive development in very low birth weight children during the first six years of life, Pediatrics, 99, 383, 10.1542/peds.99.3.383 Ment, 2003, Change in cognitive function over time in very low-birth-weight infants, JAMA, 289, 705, 10.1001/jama.289.6.705 Morris, 2002, Patterns of physical and neurologic development in preterm children, J Perinatol, 22, 31, 10.1038/sj.jp.7210590 Tommiska, 2003, A national two year follow up of extremely low birthweight infants born in 1996-1997, Arch Dis Child Fetal Neonatal Ed, 88, F29, 10.1136/fn.88.1.F29 Vollmer, 2003, Predictors of long-term outcome in very preterm infants: gestational age versus neonatal cranial ultrasound, Pediatrics, 112, 1108, 10.1542/peds.112.5.1108 Papile, 1978, Incidence and evolution of the subependymal intraventricular hemorrhage: a study of infants with weights less than 1500 grams, J Pediatr, 92, 529, 10.1016/S0022-3476(78)80282-0 Volpe, 2001 Whitelaw, 2001, Intraventricular haemorrhage and posthaemorrhagic hydrocephalus: pathogenesis, prevention and future interventions, Semin Neonatol, 6, 135, 10.1053/siny.2001.0047 Arzoumanian, 2003, Diffusion tensor brain imaging findings at term-equivalent age may predict neurologic abnormalities in low birth weight preterm infants, AJNR Am J Neuroradiol, 24, 1646 de Vries, 2001, Unilateral parenchymal haemorrhagic infarction in the preterm infant, Eur J Paediatr Neurol, 5, 139, 10.1053/ejpn.2001.0494 Krishnamoorthy, 1979, Neurologic sequelae in the survivors of neonatal intraventricular hemorrhage, Pediatrics, 64, 233, 10.1542/peds.64.2.233 Ment, 2002, Practice parameter: neuroimaging of the neonate, Neurology, 58, 1726, 10.1212/WNL.58.12.1726 Pinto-Martin, 1999, Relation of cranial ultrasound abnormalities in low-birthweight infants to motor or cognitive performance at ages 2, 6 and 9 years, Dev Med Child Neurol, 41, 826, 10.1017/S0012162299001644 Szymonowicz, 1986, Neurodevelopmental outcome of periventricular hemorrhage and leukomalacia in infants, Early Hum Dev, 14, 1, 10.1016/0378-3782(86)90164-7 Vohr, 1992, Effects of intraventricular hemorrhage and socioeconomic status of perceptual cognitive and neurologic status of low birth weight infants at 5 years of age, J Pediatr, 121, 280, 10.1016/S0022-3476(05)81204-1 Vohr, 2003, School age outcomes of very low birth weight infants in the indomethacin intraventricular hemorrhage prevention trial, Pediatrics, 111, e340, 10.1542/peds.111.4.e340 Ancel, 2005, Are maternal hypertension and small-for-gestational age risk factors for severe intraventricular hemorrhage and cystic periventricular leukomalacia? Results of the EPIPAGE cohort study, Am J Obstet Gynecol, 193, 178, 10.1016/j.ajog.2004.11.057 Hall, 2005, Morphine, hypotension, and adverse outcomes among preterm neonates: who's to blame? Secondary results from the NEOPAIN Trial, Pediatrics, 115, 1351, 10.1542/peds.2004-1398 Kaiser, 2006, Hypercapnia during the first 3 days of life is associated with severe intraventricular hemorrhage in very low birth weight infants, J Perinatol, 26, 279, 10.1038/sj.jp.7211492 Kluckow, 2005, Low systemic blood flow and pathophysiology of the preterm transitional circulation, Early Hum Dev, 81, 429, 10.1016/j.earlhumdev.2005.03.006 Linder, 2003, Risk factors for intraventricular hemorrhage in very low birth weight premature infants: a retrospective case-control study, Pediatrics, 111, e590, 10.1542/peds.111.5.e590 Osborne, 2004, Early volume expansion for prevention of morbidity and mortality in very preterm infants, Cochrane Database Syst Rev, 2, 10.1002/14651858.CD002055.pub2 Synnes, 2001, Variations in intraventricular hemorrhage incidence rates among Canadian neonatal intensive care units, J Pediatr, 138, 525, 10.1067/mpd.2001.111822 Leffler, 1986, Effects of Indomethacin on cardiac outcome distribution in normal and asphyxiated piglets, Prostaglandins, 31, 183, 10.1016/0090-6980(86)90045-6 Leffler, 1985, Effects of indomethacin upon cerebral hemodynamics of newborn pigs, Pediatr Res, 19, 1160, 10.1203/00006450-198511000-00009 Ment, 1983, Beagle puppy model of intraventicular hemorrhage. Effect of indomethacin on cerebral blood flow, J Neurosurg, 58, 857, 10.3171/jns.1983.58.6.0857 Ackerman, 2004, Epidermal growth factor and interleukin-1 (beta) utilize divergent signaling pathways to synergistically upregulate cyclooxygenase-2 gene expression in human amnion-derived WISH cells, Biol Reprod, 71, 2079, 10.1095/biolreprod.104.030841 Dammann, 2004, Inflammatory brain damage in preterm newborns - dry numbers, wet lab, and causal inferences, Early Hum Dev, 79, 1, 10.1016/j.earlhumdev.2004.04.009 Hedtjarn, 2004, Global gene expression in the immature brain after hypoxia-ischemia, J Cereb Blood Flow Metab, 24, 1317, 10.1097/01.WCB.0000141558.40491.75 Heep, 2003, Increased serum levels of interleukin 6 are associated with severe intraventricular haemorrhage in extremely premature infants, Arch Dis Child Fetal Neonatal Ed, 88, F501, 10.1136/fn.88.6.F501 Kuwano, 2004, Cyclooxygenase 2 is a key enzyme for inflammatory cytokine-induced angiogenesis, FASEB J, 18, 300, 10.1096/fj.03-0473com Pan, 2004, Screening anti-inflammatory compounds in injured spinal cord with microarrays: a comparison of bioinformatics analysis approaches, Physiol Genomics, 17, 201, 10.1152/physiolgenomics.00177.2003 Parfenova, 2002, COX-1 and COX-2 contributions to basal and IL-1 beta-stimulated prostanoid synthesis in human neonatal microvascular endothelial cells, Pediatr Res, 52, 342 Ribeiro, 2004, Epidermal growth factor modulation of prostaglandins and nitrite biosynthesis in rat fetal membranes, Prostaglandins Leukot Essent Fatty Acids, 70, 33, 10.1016/j.plefa.2003.08.003 Richardson, 2003, Epidermal growth factor receptors and cyclooxygenase-2 in the pathogenesis of non-small cell lung cancer: potential targets for chemoprevention and systemic therapy, Lung Cancer, 39, 1, 10.1016/S0169-5002(02)00382-3 Seibert, 1995, Mediation of inflammation by cyclooxygenase-2, Agents Actions Suppl, 46, 41 Stanimirovic, 2000, Inflammatory mediators of cerebral endothelium, Brain Pathol, 10, 113, 10.1111/j.1750-3639.2000.tb00248.x Takada, 2004, Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expresion cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation, Oncogene, 23, 9247, 10.1038/sj.onc.1208169 Smith, 1994, Interactions of PGH synthase isozymes-1 and -2 with NSAIDs, Ann N Y Acad Sci, 774, 50, 10.1111/j.1749-6632.1994.tb52723.x Chao, 1992, Activated microglia mediate neuronal cell injury via a nitric oxide mechanism, J Immunol, 149, 2736, 10.4049/jimmunol.149.8.2736 Colton, 1993, Microglia, an in vivo source of reactive oxygen species in the brain, Adv Neurol, 59, 321 Possel, 2000, Selective upregulation of inducible nitric oxide synthase (INOS) by lipopolysaccharide (LPS) and cytokines in microglia: in vitro and in vivo studies, Glia, 32, 51, 10.1002/1098-1136(200010)32:1<51::AID-GLIA50>3.0.CO;2-4 Rezaie, 2005, Microglia in the cerebral wall of the human telencephalon at second trimester, Cereb Cortex, 15, 938, 10.1093/cercor/bhh194 Akundi, 2005, Signal transduction pathways regulating cyclooxygenase-2 in lipopolysaccharide-actived primary rat microglia, Glia, 51, 199, 10.1002/glia.20198 Folkert, 2004, Developmental lag in superoxide dismutases relative to other antioxidant enzymes in premyelinated telencephalic white matter, J Neuropathol Exp Neurol, 63, 990, 10.1093/jnen/63.9.990 Debus, 1998, Factor V Leiden and genetic defects of thrombophilia in childhoold porencephaly, Arch Dis Child Fetal Neonatal Ed, 78, 121, 10.1136/fn.78.2.F121 Gopel, 2001, Low prevalence of large intraventricular haemorrhage in very low birthweight infants carrying the factor V Leiden or prothrombin G20210A mutation, Acta paediatr, 90, 1021, 10.1111/j.1651-2227.2001.tb01358.x Gopel, 2002, The effect of the Val37Leu polymorphism in the factor XIII gene in infants with a birth weight below 1500 g, J Pediatr, 140, 688, 10.1067/mpd.2002.123666 Petaaja, 2001, Increased risk of intraventricular hemorrhage in preterm infants with thrombophilia, Pediatr Res, 49, 643, 10.1203/00006450-200105000-00006 Adcock, 2003, The TNF-alpha - 308, MCP - 1-2518 and TGF - beta 1 + 915 polymorphisms are not associated with the development of chronic lung disease in very low birth weight infants, Genes Immun, 4, 420, 10.1038/sj.gene.6363986 Alberts, 2005, Update on the genetics of stroke and cerebrovascular disease 2005, Stroke, 36, 179, 10.1161/01.STR.0000153066.74217.31 Gould, 2005, Mutations in Col4a1 cause perinatal cerebral hemorrhage and porencephaly, Science, 308, 1167, 10.1126/science.1109418 Gould, 2006, Role of COL4A1 in small-vessel disease and hemorrhagic stroke, N Engl J Med, 354, 1489, 10.1056/NEJMoa053727 Woo, 2002, Genetic and environmental risk factors for intracerebral hemorrhage: preliminary results of a population-based study, Stroke, 33, 1190, 10.1161/01.STR.0000014774.88027.22 Gopel, 2006, Interleukin-6-174-genotype, sepsis and cerebral injury in very low birth weight infants, Genes Immun, 7, 65, 10.1038/sj.gene.6364264 Harding, 2004, Does interleukin-6 genotype influence cerebral injury or developmental progress after preterm birth?, Pediatrics, 114, 941, 10.1542/peds.2003-0494-F Harding, 2005, Variation in the interleukin-6 gene is associated with impaired cognitive development in children born prematurely: a preliminary study, Pediatr Res, 58, 117, 10.1203/01.PDR.0000163523.49021.53 Choi, 2005, Thrombin-induced oxidative stress contributes to the death of hippocampal neurons in viv: role of microglial NADPH oxidase, J Neurosci, 25, 4082, 10.1523/JNEUROSCI.4306-04.2005 Dammann, 2005, Lung and brain damage in preterm newborns and their association with gestational age, prematurity subgroup, infection/inflammation and longterm outcome, BJOG, 112, 4, 10.1111/j.1471-0528.2005.00576.x Leviton, 2004, Coagulation, inflammation, and risk of neonatal white matter disease, Pediatr Res, 55, 541, 10.1203/01.PDR.0000121197.24154.82 Volpe, 1997, Brain injury in the premature infant, Clin Perinatol, 24, 567, 10.1016/S0095-5108(18)30159-3 Whitelaw, 2007, Randomized clinical trial of prevention of hydrocephalus after intraventricular hemorrhage in preterm infants: brain-washing versus tapping fluid, Pediatrics, 119, e1071, 10.1542/peds.2006-2841 Whitelaw, 2007, Intraventricular streptokinase after intraventricular hemorrhage in newborn infants, Cochrane Database Syst Rev, 4, 10.1002/14651858.CD000498.pub2 Wellons J, Shannon C, Oakes W, et al. Comparison of conversion rates from temporary CSF management to permanent shunting in premature IVH infants. Presented at the 36th Annual Meeting of the AANS/CNS Section on Pediatric Neurological Surgery. South Beach (Miami), Florida, November 26–December 1, 2007. p. 35. Banker, 1962, Periventricular leukomalacia of infancy: a form of neonatal anoxic encephalopathy, Arch Neurol, 7, 32, 10.1001/archneur.1962.04210050022004 Deguchi, 1997, Characteristic neuropathology of leukomalacia in extremely low birth weight infants, Pediatr Neurol, 16, 296, 10.1016/S0887-8994(97)00041-6 Grant, 1986, Periventricular leukomalacia in combination with intraventricular hemorrhage: sonographic features and sequelae, AJNR Am J Neuroradiol, 7, 443 Bax, 2006, Clinical and MRI correlates of cerebral palsy: the European Cerebral Palsy Study, JAMA, 296, 1602, 10.1001/jama.296.13.1602 Graham, 1987, Prediction of cerebral palsy in very low birthweight infants: prospective ultrasound study, Lancet, 2, 593, 10.1016/S0140-6736(87)92986-2 Ment, 2006, Intraventricular hemorrhage of the preterm neonate, Vol I, 309 Synnes, 2006, Neonatal intensive care unit characteristics affect the incidence of severe intraventricular hemorrhage, Med Care, 44, 754, 10.1097/01.mlr.0000218780.16064.df Whitelaw, 2007, Postnatal phenobarbital for the prevention of intraventricular hemorrhage in preterm infants, Cochrane Database Syst Rev, 4, 10.1002/14651858.CD001691.pub2 Kuban, 1986, Neonatal intracranial hemorrhage and phenobarbital, Pediatrics, 77, 443, 10.1542/peds.77.4.443 Donn, 1981, Prevention of intraventricular hemorrhage in preterm infants by phenobarbitone: a controlled trial, Lancet, 2, 215, 10.1016/S0140-6736(81)90470-0 Pourcyrous, 1999, Cerebrovascular responses to therapeutic dose of indomethacin in newborn pigs, Pediatr Res, 45, 582, 10.1203/00006450-199904010-00019 Van Bel, 1993, The influence of indomethacin on the autoregulatory ability of the cerebral vascular bed in the newborn lamb, Pediatr Res, 34, 278, 10.1203/00006450-199308000-00015 Ment, 1992, Indomethacin promotes germinal matrix microvessel maturation in the newborn beagle pup, Stroke, 23, 1132, 10.1161/01.STR.23.8.1132 Ment, 1994, Low dose indomethacin and prevention of intraventicular hemorrhage: A multicenter randomized trial, Pediatrics, 93, 543, 10.1542/peds.93.4.543 Schmidt, 2001, Long-term effects of indomethacin prophylaxis in extremely-low-birth-weight infants, N Engl J Med, 344, 1966, 10.1056/NEJM200106283442602 Harding, 2007, Cognitive outcome and cyclo-oxygenase-2 gene (-765 G/C) variation in the preterm infant, Arch Dis Child Fetal Neonatal Ed, 92, F108, 10.1136/adc.2006.099499 Scheel, 2005, Quantitative analysis of gene expression in living adult neural stem cells by gene trapping, Nat Methods, 2, 363, 10.1038/nmeth755 Monje, 2003, Inflammatory blockade restores adult hippocampal neurogenesis, Science, 302, 1760, 10.1126/science.1088417 Fowlie, 2003, Prophylactic indomethacin for preterm infants: a systematic review and meta-analysis, Arch Dis Child Fetal Neonatal Ed, 88, F464, 10.1136/fn.88.6.F464 Ment, 2004, Indomethacin for the prevention of intraventricular hemorrhage is effective only in boys, J Pediatr, 145, 832, 10.1016/j.jpeds.2004.07.035 Chemtob, 1991, Differences in the effects in the newborn piglet of various nonsteroidal anti-inflamatory drugs on cerebral blood flow but not on cerebrovascular protaglandin, Pediatr Res, 30, 106, 10.1203/00006450-199107000-00021 Aranda, 2006, Systematic review: intravenous Ibuprofen in preterm newborns, Semin Perinatol, 30, 114, 10.1053/j.semperi.2006.04.003 Brinkhous, 1989, Effect of recombinant factor VIIa on the hemostatic defect in dogs with hemophilia A, hemophilia B, and von Willebrand disease, Proc Natl Acad Sci U S A, 86, 1382, 10.1073/pnas.86.4.1382 Macik, 1993, Safety and initial clinical efficacy of three dose levels of recombinant activated factor VII (rFVIIa): results of a phase I study, Blood Coagul Fibrinolysis, 4, 521, 10.1097/00001721-199308000-00001 Labattaglia, 2007, Recombinant activated factor VII: current perspectives and Epworth experience, Heart Lung Circ, 16, S96, 10.1016/j.hlc.2007.05.011 Ghorashian, 2004, “Off-license” use of recombinant activated factor VII, Blood Rev, 18, 245, 10.1016/j.blre.2003.12.003 Greisen, 2003, Recombinant factor VIIa in preterm neonates with prolonged prothrombin time, Blood Coagul Fibrinolysis, 14, 117, 10.1097/00001721-200301000-00021 Brady, 2006, Recombinant activated factor VII (rFVIIa) treatment in infants with hemorrhage, Paediatr Anaesth, 16, 1042, 10.1111/j.1460-9592.2006.02039.x Mitsiakos, 2007, Is the use of rFVIIa safe and effective in bleeding neonates? A retrospective series of 8 cases, J Pediatr Hematol Oncol, 29, 145, 10.1097/MPH.0b013e3180335bcb Robertson, 2006, Prevention of intraventricular haemorrhage: a role for recombinant activated factor VII?, J Paediatr Child Health, 42, 325, 10.1111/j.1440-1754.2006.00867.x Chiswick, 1991, Vitamin E supplementation and periventricular hemorrhage in the newborn, Am J Clin Nutr, 53, 370S, 10.1093/ajcn/53.1.370S Cools, 2005, Neuromuscular paralysis for newborn infants receiving mechanical ventilation, Cochrane Database Syst Rev, 2, 10.1002/14651858.CD002773.pub2