Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Journal of Medicinal Chemistry - Tập 45 Số 12 - Trang 2615-2623 - 2002
Daniel F. Veber1, Stephen R. Johnson1, Hung‐Yuan Cheng1, Brian R. Smith1, Keith W. Ward1, Kenneth D. Kopple1
1Departments of Medicinal Chemistry, Cheminformatics, Computational Analytical and Structural Sciences, and Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, 709 Swedeland Road, P. O. Box 1539, King of Prussia, Pennsylvania 19406-0939

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