Ezh1 and Ezh2 Maintain Repressive Chromatin through Different Mechanisms
Tóm tắt
Từ khóa
Tài liệu tham khảo
Abel, 1996, Characterization of EZH1, a human homolog of Drosophila Enhancer of zeste near BRCA1, Genomics, 37, 161, 10.1006/geno.1996.0537
An, 2004, Reconstitution and transcriptional analysis of chromatin in vitro, Methods Enzymol., 377, 460, 10.1016/S0076-6879(03)77030-X
Aoto, 2008, Polycomb group protein-associated chromatin is reproduced in post-mitotic G1 phase and required for S-phase progression, J. Biol. Chem., 283, 18905, 10.1074/jbc.M709322200
Bachmann, 2006, EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast, J. Clin. Oncol., 24, 268, 10.1200/JCO.2005.01.5180
Bernstein, 2006, Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin, Mol. Cell. Biol., 26, 2560, 10.1128/MCB.26.7.2560-2569.2006
Blais, 2005, An initial blueprint for myogenic differentiation, Genes Dev., 19, 553, 10.1101/gad.1281105
Boyer, 2006, Polycomb complexes repress developmental regulators in murine embryonic stem cells, Nature, 441, 349, 10.1038/nature04733
Bracken, 2003, EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer, EMBO J., 22, 5323, 10.1093/emboj/cdg542
Bracken, 2006, Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions, Genes Dev., 20, 1123, 10.1101/gad.381706
Cao, 2004, SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex, Mol. Cell, 15, 57, 10.1016/j.molcel.2004.06.020
Cao, 2002, Role of histone H3 lysine 27 methylation in Polycomb-group silencing, Science, 298, 1039, 10.1126/science.1076997
Denisenko, 1997, The product of the murine homolog of the Drosophila extra sex combs gene displays transcriptional repressor activity, Mol. Cell. Biol., 17, 4707, 10.1128/MCB.17.8.4707
Dorigo, 2004, Nucleosome arrays reveal the two-start organization of the chromatin fiber, Science, 306, 1571, 10.1126/science.1103124
Etchegaray, 2006, The polycomb group protein EZH2 is required for mammalian circadian clock function, J. Biol. Chem., 281, 21209, 10.1074/jbc.M603722200
Francis, 2004, Chromatin compaction by a polycomb group protein complex, Science, 306, 1574, 10.1126/science.1100576
Gillespie, 2007, Retinoid regulated association of transcriptional co-regulators and the polycomb group protein SUZ12 with the retinoic acid response elements of Hoxa1, RARbeta(2), and Cyp26A1 in F9 embryonal carcinoma cells, J. Mol. Biol., 372, 298, 10.1016/j.jmb.2007.06.079
Griffith, 1978, Electron microscope visualization of chromatin and other DNA-protein complexes, Annu. Rev. Biophys. Bioeng., 7, 19, 10.1146/annurev.bb.07.060178.000315
Gunster, 2001, Differential expression of human Polycomb group proteins in various tissues and cell types, J. Cell. Biochem. Suppl., 36, 129, 10.1002/jcb.1093
Han, 2007, Structural basis of EZH2 recognition by EED, Structure, 15, 1306, 10.1016/j.str.2007.08.007
Jones, 1998, The Drosophila esc and E(z) proteins are direct partners in polycomb group-mediated repression, Mol. Cell. Biol., 18, 2825, 10.1128/MCB.18.5.2825
Ketel, 2005, Subunit contributions to histone methyltransferase activities of fly and worm polycomb group complexes, Mol. Cell. Biol., 25, 6857, 10.1128/MCB.25.16.6857-6868.2005
Kirmizis, 2003, Identification of the polycomb group protein SU(Z)12 as a potential molecular target for human cancer therapy, Mol. Cancer Ther., 2, 113
Klymenko, 2006, A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities, Genes Dev., 20, 1110, 10.1101/gad.377406
Kuzmichev, 2002, Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein, Genes Dev., 16, 2893, 10.1101/gad.1035902
Kuzmichev, 2004, Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3, Mol. Cell, 14, 183, 10.1016/S1097-2765(04)00185-6
Kuzmichev, 2005, Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation, Proc. Natl. Acad. Sci. USA, 102, 1859, 10.1073/pnas.0409875102
Laible, 1997, Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres, EMBO J., 16, 3219, 10.1093/emboj/16.11.3219
Lee, 2006, Control of developmental regulators by Polycomb in human embryonic stem cells, Cell, 125, 301, 10.1016/j.cell.2006.02.043
Lee, 2007, High histone acetylation and decreased polycomb repressive complex 2 member levels regulate gene specific transcriptional changes during early embryonic stem cell differentiation induced by retinoic acid, Stem Cells, 25, 2191, 10.1634/stemcells.2007-0203
Levine, 2002, The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans, Mol. Cell. Biol., 22, 6070, 10.1128/MCB.22.17.6070-6078.2002
Metivier, 2003, Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter, Cell, 115, 751, 10.1016/S0092-8674(03)00934-6
Metsuyanim, 2008, Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes, Stem Cells, 26, 1808, 10.1634/stemcells.2007-0322
Muller, 2002, Histone methyltransferase activity of a Drosophila Polycomb group repressor complex, Cell, 111, 197, 10.1016/S0092-8674(02)00976-5
Nikitina, 2007, Multiple modes of interaction between the methylated DNA binding protein MeCP2 and chromatin, Mol. Cell. Biol., 27, 864, 10.1128/MCB.01593-06
Nishioka, 2002, PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin, Mol. Cell, 9, 1201, 10.1016/S1097-2765(02)00548-8
O'Carroll, 2000, Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression, Mol. Cell. Biol., 20, 9423, 10.1128/MCB.20.24.9423-9433.2000
O'Carroll, 2001, The polycomb-group gene Ezh2 is required for early mouse development, Mol. Cell. Biol., 21, 4330, 10.1128/MCB.21.13.4330-4336.2001
O'Donnell, 2008, MAP kinase-mediated c-fos regulation relies on a histone acetylation relay switch, Mol. Cell, 29, 780, 10.1016/j.molcel.2008.01.019
Ogawa, 1998, Cloning and expression of a human/mouse Polycomb group gene, ENX-2/Enx-2, Biochim. Biophys. Acta, 1395, 151, 10.1016/S0167-4781(97)00156-5
Ogawa, 2003, The Polycomb-group protein ENX-2 interacts with ZAP-70, Immunol. Lett., 86, 57, 10.1016/S0165-2478(02)00293-6
Orphanides, 1998, FACT, a factor that facilitates transcript elongation through nucleosomes, Cell, 92, 105, 10.1016/S0092-8674(00)80903-4
Pasini, 2004, Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity, EMBO J., 23, 4061, 10.1038/sj.emboj.7600402
Pavri, 2006, Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II, Cell, 125, 703, 10.1016/j.cell.2006.04.029
Peters, 2001, Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability, Cell, 107, 323, 10.1016/S0092-8674(01)00542-6
Prince, 2002, Splitting pairs: the diverging fates of duplicated genes, Nat. Rev. Genet., 3, 827, 10.1038/nrg928
Ringrose, 2007, Polycomb/Trithorax response elements and epigenetic memory of cell identity, Development, 134, 223, 10.1242/dev.02723
Rinn, 2007, Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs, Cell, 129, 1311, 10.1016/j.cell.2007.05.022
Sarma, 2008, Ezh2 requires PHF1 to efficiently catalyze H3 lysine 27 trimethylation in vivo, Mol. Cell. Biol., 28, 2718, 10.1128/MCB.02017-07
Schoeftner, 2006, Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing, EMBO J., 25, 3110, 10.1038/sj.emboj.7601187
Schotta, 2004, A silencing pathway to induce H3–K9 and H4–K20 trimethylation at constitutive heterochromatin, Genes Dev., 18, 1251, 10.1101/gad.300704
Schuettengruber, 2007, Genome regulation by polycomb and trithorax proteins, Cell, 128, 735, 10.1016/j.cell.2007.02.009
Schwartz, 2006, Genome-wide analysis of Polycomb targets in Drosophila melanogaster, Nat. Genet., 38, 700, 10.1038/ng1817
Shao, 1999, Stabilization of chromatin structure by PRC1, a Polycomb complex, Cell, 98, 37, 10.1016/S0092-8674(00)80604-2
Sims, 2007, Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing, Mol. Cell, 28, 665, 10.1016/j.molcel.2007.11.010
Song, 2008, Structural basis of histone H4 recognition by p55, Genes Dev., 22, 1313, 10.1101/gad.1653308
Squazzo, 2006, Suz12 binds to silenced regions of the genome in a cell-type-specific manner, Genome Res., 16, 890, 10.1101/gr.5306606
Su, 2003, Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement, Nat. Immunol., 4, 124, 10.1038/ni876
Su, 2005, Polycomb group protein ezh2 controls actin polymerization and cell signaling, Cell, 121, 425, 10.1016/j.cell.2005.02.029
Taneja, 2005, Cell-specific regulation of androgen receptor phosphorylation in vivo, J. Biol. Chem., 280, 40916, 10.1074/jbc.M508442200
Terranova, 2008, Polycomb group proteins Ezh2 and Rnf2 direct genomic contraction and imprinted repression in early mouse embryos, Dev. Cell, 15, 10.1016/j.devcel.2008.08.015
Tie, 2007, The N terminus of Drosophila ESC binds directly to histone H3 and is required for E(Z)-dependent trimethylation of H3 lysine 27, Mol. Cell. Biol., 27, 2014, 10.1128/MCB.01822-06
Tolhuis, 2006, Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster, Nat. Genet., 38, 694, 10.1038/ng1792
Trojer, 2007, L3MBTL1, a histone-methylation-dependent chromatin lock, Cell, 129, 915, 10.1016/j.cell.2007.03.048
van Lohuizen, 1998, Interaction of mouse polycomb-group (Pc-G) proteins Enx1 and Enx2 with Eed: indication for separate Pc-G complexes, Mol. Cell. Biol., 18, 3572, 10.1128/MCB.18.6.3572
Vaquero, 2004, Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin, Mol. Cell, 16, 93, 10.1016/j.molcel.2004.08.031
Verreault, 1998, Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase, Curr. Biol., 8, 96, 10.1016/S0960-9822(98)70040-5
Wang, 2004, Role of histone H2A ubiquitination in Polycomb silencing, Nature, 431, 873, 10.1038/nature02985
Wang, 2004, Hierarchical recruitment of polycomb group silencing complexes, Mol. Cell, 14, 637, 10.1016/j.molcel.2004.05.009
Whitcomb, 2007, Polycomb Group proteins: an evolutionary perspective, Trends Genet., 23, 494, 10.1016/j.tig.2007.08.006