IRSp53: crossing the road of membrane and actin dynamics in the formation of membrane protrusions

Pollard, 2003, Cellular motility driven by assembly and disassembly of actin filaments, Cell, 112, 453, 10.1016/S0092-8674(03)00120-X Carlier, 2007, Control of actin assembly dynamics in cell motility, J. Biol. Chem., 282, 23005, 10.1074/jbc.R700020200 Bretscher, 1996, Moving membrane up to the front of migrating cells, Cell, 85, 465, 10.1016/S0092-8674(00)81246-5 Kucik, 1990, Cell migration does not produce membrane flow, J. Cell Biol., 111, 1617, 10.1083/jcb.111.4.1617 Traynor, 2007, Possible roles of the endocytic cycle in cell motility, J. Cell Sci., 120, 2318, 10.1242/jcs.007732 Jekely, 2005, Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration, Dev. Cell, 9, 197, 10.1016/j.devcel.2005.06.004 Wang, 2006, Analysis of cell migration using whole-genome expression profiling of migratory cells in the Drosophila ovary, Dev. Cell, 10, 483, 10.1016/j.devcel.2006.02.003 Minina, 2007, Control of receptor internalization, signaling level, and precise arrival at the target in guided cell migration, Curr. Biol., 17, 1164, 10.1016/j.cub.2007.05.073 Okamumoho, 1999, Cloning and characterization of cDNA for DRPLA interacting protein, Nippon Rinsho, 57, 856 Oda, 1999, Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1, Cytogenet. Cell Genet., 84, 75, 10.1159/000015219 Abbott, 1999, The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses, J. Neurosci., 19, 7300, 10.1523/JNEUROSCI.19-17-07300.1999 Lee, 2002, MIM, a potential metastasis suppressor gene in bladder cancer, Neoplasia, 4, 291, 10.1038/sj.neo.7900231 Machesky, 2007, MIM: a multifunctional scaffold protein, J. Mol. Med., 85, 569, 10.1007/s00109-007-0207-0 Mattila, 2003, Mouse MIM, a tissue-specific regulator of cytoskeletal dynamics, interacts with ATP-actin monomers through its C-terminal WH2 domain, J. Biol. Chem., 278, 8452, 10.1074/jbc.M212113200 Lee, 2007, Structural basis for the actin-binding function of missing-in-metastasis, Structure, 15, 145, 10.1016/j.str.2006.12.005 Yamagishi, 2004, A novel actin bundling/filopodium-forming domain conserved in insulin receptor tyrosine kinase substrate p53 and missing in metastasis protein, J. Biol. Chem., 279, 14929, 10.1074/jbc.M309408200 Okamura-Oho, 2001, Distinctive tissue distribution and phosphorylation of IRSp53 isoforms, Biochem. Biophys. Res. Commun., 289, 957, 10.1006/bbrc.2001.6102 Miyahara, 2003, Genomic structure and alternative splicing of the insulin receptor tyrosine kinase substrate of 53-kDa protein, J. Hum. Genet., 48, 410, 10.1007/s10038-003-0047-x Alvarez, 2002, Novel isoform of insulin receptor substrate p53/p58 is generated by alternative splicing in the CRIB/SH3-binding region, J. Biol. Chem., 277, 24728, 10.1074/jbc.M202512200 Mattila, 2007, Missing-in-metastasis and IRSp53 deform PI(4,5)P2-rich membranes by an inverse BAR domain-like mechanism, J. Cell Biol., 176, 953, 10.1083/jcb.200609176 Millard, 2005, Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53, EMBO J., 24, 240, 10.1038/sj.emboj.7600535 Suetsugu, 2006, The RAC binding domain/IRSp53-MIM homology domain of IRSp53 induces RAC-dependent membrane deformation, J. Biol. Chem., 281, 35347, 10.1074/jbc.M606814200 Miki, 2000, IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling, Nature, 408, 732, 10.1038/35047107 Choi, 2005, Regulation of dendritic spine morphogenesis by insulin receptor substrate 53, a downstream effector of Rac1 and Cdc42 small GTPases, J. Neurosci., 25, 869, 10.1523/JNEUROSCI.3212-04.2005 Bompard, 2005, Involvement of Rac in actin cytoskeleton rearrangements induced by MIM-B, J. Cell Sci., 118, 5393, 10.1242/jcs.02640 Frost, 2007, F-BAR proteins join the BAR family fold, Structure, 15, 751, 10.1016/j.str.2007.06.006 Shimada, 2007, Curved EFC/F-BAR-domain dimers are joined end to end into a filament for membrane invagination in endocytosis, Cell, 129, 761, 10.1016/j.cell.2007.03.040 Peter, 2004, BAR domains as sensors of membrane curvature: the amphiphysin BAR structure, Science, 303, 495, 10.1126/science.1092586 Krugmann, 2001, Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex, Curr. Biol., 11, 1645, 10.1016/S0960-9822(01)00506-1 Funato, 2004, IRSp53/Eps8 complex is important for positive regulation of Rac and cancer cell motility/invasiveness, Cancer Res., 64, 5237, 10.1158/0008-5472.CAN-04-0327 Disanza, 2006, Regulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complex, Nat. Cell Biol., 8, 1337, 10.1038/ncb1502 Fujiwara, 2000, Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2, Biochem. Biophys. Res. Commun., 271, 626, 10.1006/bbrc.2000.2671 Sekerkova, 2003, Novel espin actin-bundling proteins are localized to Purkinje cell dendritic spines and bind the Src homology 3 adapter protein insulin receptor substrate p53, J. Neurosci., 23, 1310, 10.1523/JNEUROSCI.23-04-01310.2003 Okamura-Oho, 1999, Dentatorubral-pallidoluysian atrophy protein interacts through a proline-rich region near polyglutamine with the SH3 domain of an insulin receptor tyrosine kinase substrate, Hum. Mol. Genet., 8, 947, 10.1093/hmg/8.6.947 Bockmann, 2002, ProSAP/Shank postsynaptic density proteins interact with insulin receptor tyrosine kinase substrate IRSp53, J. Neurochem., 83, 1013, 10.1046/j.1471-4159.2002.01204.x Soltau, 2002, The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42, Mol. Cell. Neurosci., 21, 575, 10.1006/mcne.2002.1201 Yanagida-Asanuma, 2007, Synaptopodin protects against proteinuria by disrupting Cdc42:IRSp53:Mena signaling complexes in kidney podocytes, Am. J. Pathol., 171, 415, 10.2353/ajpath.2007.070075 Dominguez, 2007, The beta-thymosin/WH2 fold: multifunctionality and structure, Ann. N. Y. Acad. Sci., 1112, 86, 10.1196/annals.1415.011 Millard, 2007, Characterisation of IRTKS, a novel IRSp53/MIM family actin regulator with distinct filament bundling properties, J. Cell Sci., 120, 1663, 10.1242/jcs.001776 Govind, 2001, Cdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actin, J. Cell Biol., 152, 579, 10.1083/jcb.152.3.579 Suetsugu, 2006, Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP(3), and Rac, J. Cell Biol., 173, 571, 10.1083/jcb.200509067 Ranganathan, 1997, PDZ domain proteins: scaffolds for signaling complexes, Curr. Biol., 7, R770, 10.1016/S0960-9822(06)00401-5 Zimmermann, 2006, PDZ domain-phosphoinositide interactions in cell-signaling, Verh. K. Acad. Geneeskd. Belg., 68, 271 Nourry, 2003, PDZ domain proteins: plug and play!, Sci. STKE, 2003, RE7, 10.1126/stke.2003.179.re7 Kim, 2004, PDZ domain proteins of synapses, Nat. Rev. Neurosci., 5, 771, 10.1038/nrn1517 Soltau, 2004, Insulin receptor substrate of 53kDa links postsynaptic shank to PSD-95, J. Neurochem., 90, 659, 10.1111/j.1471-4159.2004.02523.x Hori, 2005, NMDA receptor-dependent synaptic translocation of insulin receptor substrate p53 via protein kinase C signaling, J. Neurosci., 25, 2670, 10.1523/JNEUROSCI.3638-04.2005 Hori, 2003, MALS is a binding partner of IRSp53 at cell-cell contacts, FEBS Lett., 554, 30, 10.1016/S0014-5793(03)01074-3 Nakagawa, 2003, IRSp53 is colocalised with WAVE2 at the tips of protruding lamellipodia and filopodia independently of Mena, J. Cell Sci., 116, 2577, 10.1242/jcs.00462 Woodings, 2003, MIM-B, a putative metastasis suppressor protein, binds to actin and to protein tyrosine phosphatase delta, Biochem. J., 371, 463, 10.1042/bj20021962 Gonzalez-Quevedo, 2005, Receptor tyrosine phosphatase-dependent cytoskeletal remodeling by the hedgehog-responsive gene MIM/BEG4, J. Cell Biol., 168, 453, 10.1083/jcb.200409078 Faix, 2006, The making of filopodia, Curr. Opin. Cell Biol., 18, 18, 10.1016/j.ceb.2005.11.002 Gupton, 2007, Filopodia: the fingers that do the walking, Sci. STKE, 2007, re5, 10.1126/stke.4002007re5 Koleske, 2003, Do filopodia enable the growth cone to find its way?, Sci. STKE, 2003, pe20, 10.1126/stke.2003.183.pe20 Svitkina, 2003, Mechanism of filopodia initiation by reorganization of a dendritic network, J. Cell Biol., 160, 409, 10.1083/jcb.200210174 Bear, 2002, Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility, Cell, 109, 509, 10.1016/S0092-8674(02)00731-6 Schirenbeck, 2005, Formins and VASPs may co-operate in the formation of filopodia, Biochem. Soc. Trans., 33, 1256, 10.1042/BST0331256 Schirenbeck, 2006, The bundling activity of vasodilator-stimulated phosphoprotein is required for filopodium formation, Proc. Natl. Acad. Sci. U. S. A., 103, 7694, 10.1073/pnas.0511243103 Croce, 2004, A novel actin barbed-end-capping activity in EPS-8 regulates apical morphogenesis in intestinal cells of Caenorhabditis elegans, Nat. Cell Biol., 6, 1173, 10.1038/ncb1198 Applewhite, 2007, Ena/VASP proteins have an anti-capping independent function in filopodia formation, Mol. Biol. Cell, 18, 2579, 10.1091/mbc.e06-11-0990 Krause, 2003, Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration, Annu. Rev. Cell Dev. Biol., 19, 541, 10.1146/annurev.cellbio.19.050103.103356 Barzik, 2005, Ena/VASP proteins enhance actin polymerization in the presence of barbed end capping proteins, J. Biol. Chem., 280, 28653, 10.1074/jbc.M503957200 Samarin, 2003, How VASP enhances actin-based motility, J. Cell Biol., 163, 131, 10.1083/jcb.200303191 Hall, 2005, Rho GTPases and the control of cell behaviour, Biochem. Soc. Trans., 33, 891, 10.1042/BST0330891 Takenawa, 2001, WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell movement, J. Cell Sci., 114, 1801, 10.1242/jcs.114.10.1801 Stradal, 2005, Protein complexes regulating Arp2/3-mediated actin assembly, Curr. Opin. Cell Biol., 18, 4, 10.1016/j.ceb.2005.12.003 Takenawa, 2007, The WASP-WAVE protein network: connecting the membrane to the cytoskeleton, Nat. Rev. Mol. Cell Biol., 8, 37, 10.1038/nrm2069 Bompard, 2004, Regulation of WASP/WAVE proteins: making a long story short, J. Cell Biol., 166, 957, 10.1083/jcb.200403127 Connolly, 2005, Tiam1-IRSp53 complex formation directs specificity of rac-mediated actin cytoskeleton regulation, Mol. Cell. Biol., 25, 4602, 10.1128/MCB.25.11.4602-4614.2005 Matus, 2000, Actin dynamics in dendritic spines: a form of regulated plasticity at excitatory synapses, Hippocampus, 10, 555, 10.1002/1098-1063(2000)10:5<555::AID-HIPO5>3.0.CO;2-Z Hering, 2001, Dendritic spines: structure, dynamics and regulation, Nat. Rev. Neurosci., 2, 880, 10.1038/35104061 Okabe, 2001, NMDA receptors and their interacting proteins in the postsynaptic density, Kaibogaku Zasshi, 76, 185 Walikonis, 2000, Identification of proteins in the postsynaptic density fraction by mass spectrometry, J. Neurosci., 20, 4069, 10.1523/JNEUROSCI.20-11-04069.2000 Sheng, 2000, The Shank family of scaffold proteins, J. Cell Sci., 113, 1851, 10.1242/jcs.113.11.1851 Sala, 2001, Regulation of dendritic spine morphology and synaptic function by Shank and Homer, Neuron, 31, 115, 10.1016/S0896-6273(01)00339-7 Tamura, 2007, MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4, 0. Mol. Biol. Evol., 24, 1596, 10.1093/molbev/msm092